Allogeneic Stem Cell Transplantation

Allogeneic Stem Cell Transplantation

Author: Hillard M. Lazarus

Publisher: Springer Science & Business Media

Published: 2010-03-02

Total Pages: 885

ISBN-13: 1597454788

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Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.


Book Synopsis Allogeneic Stem Cell Transplantation by : Hillard M. Lazarus

Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.


Adult T-cell Leukemia/Lymphoma

Adult T-cell Leukemia/Lymphoma

Author: Toshiki Watanabe

Publisher: Springer

Published: 2017-04-27

Total Pages: 170

ISBN-13: 443156523X

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This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.


Book Synopsis Adult T-cell Leukemia/Lymphoma by : Toshiki Watanabe

Download or read book Adult T-cell Leukemia/Lymphoma written by Toshiki Watanabe and published by Springer. This book was released on 2017-04-27 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.


The Peripheral T-Cell Lymphomas

The Peripheral T-Cell Lymphomas

Author: Owen A. O'Connor

Publisher: John Wiley & Sons

Published: 2021-06-01

Total Pages: 434

ISBN-13: 1119671310

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THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: Covers the biological basis, epidemiology, classification, and treatment of PTCL Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.


Book Synopsis The Peripheral T-Cell Lymphomas by : Owen A. O'Connor

Download or read book The Peripheral T-Cell Lymphomas written by Owen A. O'Connor and published by John Wiley & Sons. This book was released on 2021-06-01 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: Covers the biological basis, epidemiology, classification, and treatment of PTCL Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.


Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition

Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-01-09

Total Pages: 25

ISBN-13: 1464914699

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Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Adult T-Cell Leukemia-Lymphoma in a compact format. The editors have built Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adult T-Cell Leukemia-Lymphoma in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Book Synopsis Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Adult T-Cell Leukemia-Lymphoma in a compact format. The editors have built Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adult T-Cell Leukemia-Lymphoma in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adult T-Cell Leukemia-Lymphoma: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Adult T-cell Leukaemia

Adult T-cell Leukaemia

Author: Kiyoshi Takatsuki

Publisher: Oxford University Press, USA

Published: 1994

Total Pages: 346

ISBN-13:

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Advances made so far in the worldwide study of AIDS and HIV owe much to our knowledge of T-cell leukaemia, which is the first human cancer known to be caused by a retrovirus. This book records the state-of-the-art findings on ATL and related diseases, and reviews the information which has been accumalated over the past two decades. Contributions from leading experts cover haematology, neurology, virology, epidemiology, pathophysiology, animal models, and treatment of ATL. The major contribution of ATL research to the understanding of AIDS, another retrovirus-caused disease, is clearly highlighted in this book. Contents include: ATL and HTLV-I-related diseases; regulation of HTLV-I-gene expression and its roles in ATL development; epidemiology of HTLV-I and HTLV-II infection; ethnoepidemiology of ATL in Japan, with special reference to mongoloid dispersal; ATL of Caribbean origin; molecular epidemiology of HTLV-I and HTLV-II; HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP); pathophysiology of ATL cells; cell growth characteristics; animal models of HTLV-1 infection; chemotherapy of ATL, and new approaches to the treatmant of ATL.


Book Synopsis Adult T-cell Leukaemia by : Kiyoshi Takatsuki

Download or read book Adult T-cell Leukaemia written by Kiyoshi Takatsuki and published by Oxford University Press, USA. This book was released on 1994 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances made so far in the worldwide study of AIDS and HIV owe much to our knowledge of T-cell leukaemia, which is the first human cancer known to be caused by a retrovirus. This book records the state-of-the-art findings on ATL and related diseases, and reviews the information which has been accumalated over the past two decades. Contributions from leading experts cover haematology, neurology, virology, epidemiology, pathophysiology, animal models, and treatment of ATL. The major contribution of ATL research to the understanding of AIDS, another retrovirus-caused disease, is clearly highlighted in this book. Contents include: ATL and HTLV-I-related diseases; regulation of HTLV-I-gene expression and its roles in ATL development; epidemiology of HTLV-I and HTLV-II infection; ethnoepidemiology of ATL in Japan, with special reference to mongoloid dispersal; ATL of Caribbean origin; molecular epidemiology of HTLV-I and HTLV-II; HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP); pathophysiology of ATL cells; cell growth characteristics; animal models of HTLV-1 infection; chemotherapy of ATL, and new approaches to the treatmant of ATL.


Adult T Cell Leukemia and Related Diseases

Adult T Cell Leukemia and Related Diseases

Author: Takashi Uchiyama

Publisher: Springer

Published: 1995

Total Pages: 158

ISBN-13:

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Reviews research in adult T cell leukemia (ATL), one of the central disorders related to infections caused by the retrovirus human T lymphotrophic virus (HTLV-1), for researchers and clinicians. Describes clinical features of ATL and other related diseases and biological properties of cells, explains the IL-2/IL-2 receptor system in ATL and redox regulation and ATL-derived factor, and compares the relationship between AIDS and HIV to ATL and HTLV-1. Includes bandw diagrams and photos. Annotation copyright by Book News, Inc., Portland, OR


Book Synopsis Adult T Cell Leukemia and Related Diseases by : Takashi Uchiyama

Download or read book Adult T Cell Leukemia and Related Diseases written by Takashi Uchiyama and published by Springer. This book was released on 1995 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews research in adult T cell leukemia (ATL), one of the central disorders related to infections caused by the retrovirus human T lymphotrophic virus (HTLV-1), for researchers and clinicians. Describes clinical features of ATL and other related diseases and biological properties of cells, explains the IL-2/IL-2 receptor system in ATL and redox regulation and ATL-derived factor, and compares the relationship between AIDS and HIV to ATL and HTLV-1. Includes bandw diagrams and photos. Annotation copyright by Book News, Inc., Portland, OR


Novel Therapeutics for Rare Lymphomas

Novel Therapeutics for Rare Lymphomas

Author: Christopher Dittus

Publisher: Springer

Published: 2019-12-09

Total Pages: 253

ISBN-13: 9783030256098

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This comprehensive volume reviews the clinical presentation, diagnosis, and treatment approach to rare lymphomas. There is particular emphasis placed on new diagnostic approaches, novel chemotherapy combinations, and treatment modalities with novel therapeutics. It highlights research advances in a group of diseases that are often overlooked, and serves as a single repository of information on the most recent advances in targeted small molecule inhibitors, monoclonal antibodies, immunotherapy, and CAR-T therapy as they pertain to rare types of lymphoma. Written for practicing oncologists, hematologists, fellows, and residents, Novel Therapeutics for Rare Lymphomas covers rare subtypes of lymphoma, including indolent and aggressive T-cell lymphomas and B-cell lymphomas.


Book Synopsis Novel Therapeutics for Rare Lymphomas by : Christopher Dittus

Download or read book Novel Therapeutics for Rare Lymphomas written by Christopher Dittus and published by Springer. This book was released on 2019-12-09 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume reviews the clinical presentation, diagnosis, and treatment approach to rare lymphomas. There is particular emphasis placed on new diagnostic approaches, novel chemotherapy combinations, and treatment modalities with novel therapeutics. It highlights research advances in a group of diseases that are often overlooked, and serves as a single repository of information on the most recent advances in targeted small molecule inhibitors, monoclonal antibodies, immunotherapy, and CAR-T therapy as they pertain to rare types of lymphoma. Written for practicing oncologists, hematologists, fellows, and residents, Novel Therapeutics for Rare Lymphomas covers rare subtypes of lymphoma, including indolent and aggressive T-cell lymphomas and B-cell lymphomas.


Cutaneous T-Cell Lymphoma

Cutaneous T-Cell Lymphoma

Author: Herschel S. Zackheim

Publisher: CRC Press

Published: 2004-10-28

Total Pages: 152

ISBN-13: 9780849321016

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Cutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in the disease, Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome provides comprehensive coverage of the disease and presents techniques for diagnosis and state-of-the-art treatment modalities, such as ultraviolet light, steroids, and topical chemotherapeutics.


Book Synopsis Cutaneous T-Cell Lymphoma by : Herschel S. Zackheim

Download or read book Cutaneous T-Cell Lymphoma written by Herschel S. Zackheim and published by CRC Press. This book was released on 2004-10-28 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in the disease, Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome provides comprehensive coverage of the disease and presents techniques for diagnosis and state-of-the-art treatment modalities, such as ultraviolet light, steroids, and topical chemotherapeutics.


Childhood Acute Lymphoblastic Leukemia

Childhood Acute Lymphoblastic Leukemia

Author: Ajay Vora

Publisher: Springer

Published: 2017-04-21

Total Pages: 345

ISBN-13: 3319397087

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This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.


Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.


Clinical Epidemiology of Acute Lymphoblastic Leukemia

Clinical Epidemiology of Acute Lymphoblastic Leukemia

Author: Juan Manuel Mejia-Arangure

Publisher: BoD – Books on Demand

Published: 2013-04-17

Total Pages: 346

ISBN-13: 9535109901

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This book describes different perspectives of childhood acute lymphoblastic leukemia. The approach includes aspects of molecular epidemiology, particularly molecular features that influence the genesis and prognosis of the disease. Some aspects of the prognosis of lymphoblastic leukemias are very detailed, highlighting the use of molecular biology in the early identification of complications that may occur in diseased patients. The authors of the present book conform a Mexican group who identifies the causes of leukemia, and they summarize their experience in research, results and proposals for future studies. A causal model is included in which the authors hypothesized the origin of acute lymphoblastic leukemias, particularly in children. This hypothesis can be useful to better understand other cancers during childhood. This book will help the reader to identify different molecular aspects involved in leukemia, and its relation to the development and evolution of the disease.


Book Synopsis Clinical Epidemiology of Acute Lymphoblastic Leukemia by : Juan Manuel Mejia-Arangure

Download or read book Clinical Epidemiology of Acute Lymphoblastic Leukemia written by Juan Manuel Mejia-Arangure and published by BoD – Books on Demand. This book was released on 2013-04-17 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes different perspectives of childhood acute lymphoblastic leukemia. The approach includes aspects of molecular epidemiology, particularly molecular features that influence the genesis and prognosis of the disease. Some aspects of the prognosis of lymphoblastic leukemias are very detailed, highlighting the use of molecular biology in the early identification of complications that may occur in diseased patients. The authors of the present book conform a Mexican group who identifies the causes of leukemia, and they summarize their experience in research, results and proposals for future studies. A causal model is included in which the authors hypothesized the origin of acute lymphoblastic leukemias, particularly in children. This hypothesis can be useful to better understand other cancers during childhood. This book will help the reader to identify different molecular aspects involved in leukemia, and its relation to the development and evolution of the disease.