Advanced Basic Meta-analysis

Advanced Basic Meta-analysis

Author: Brian Mullen

Publisher: Psychology Press

Published: 2013-05-13

Total Pages: 184

ISBN-13: 1134751451

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In response to the growing emphasis on precision in the summarization and integration of research literature, Advanced BASIC Meta-Analysis presents an overview of strategies, techniques, and procedures used in meta-analysis. The book and software provide an integrated and comprehensive combination of meta-analytic tools for the statistical integration of independent study results. Advanced BASIC Meta-Analysis has three distinct goals: * to provide a clear and user-friendly introduction to the procedures and rules of effective meta-analytic integration; * to present the implicit assumptions and strategies that guide successful meta-analytic integrations; and * to develop a meta-analytic database management system that allows users to create, modify, and update a database, including the relevant statistical information and predictors, for a given research domain. The companion software system allows users to perform a full complement of meta-analytic statistical functions with the speed and flexibility of a database management system. It can also construct a wide array of meta-analytic graphic displays. This text and software package serves as a useful introduction to the quantitative assessment of research domains for those new to meta-analyses. It is also a valuable sourcebook for those who have already conducted meta-analyses.


Book Synopsis Advanced Basic Meta-analysis by : Brian Mullen

Download or read book Advanced Basic Meta-analysis written by Brian Mullen and published by Psychology Press. This book was released on 2013-05-13 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the growing emphasis on precision in the summarization and integration of research literature, Advanced BASIC Meta-Analysis presents an overview of strategies, techniques, and procedures used in meta-analysis. The book and software provide an integrated and comprehensive combination of meta-analytic tools for the statistical integration of independent study results. Advanced BASIC Meta-Analysis has three distinct goals: * to provide a clear and user-friendly introduction to the procedures and rules of effective meta-analytic integration; * to present the implicit assumptions and strategies that guide successful meta-analytic integrations; and * to develop a meta-analytic database management system that allows users to create, modify, and update a database, including the relevant statistical information and predictors, for a given research domain. The companion software system allows users to perform a full complement of meta-analytic statistical functions with the speed and flexibility of a database management system. It can also construct a wide array of meta-analytic graphic displays. This text and software package serves as a useful introduction to the quantitative assessment of research domains for those new to meta-analyses. It is also a valuable sourcebook for those who have already conducted meta-analyses.

Advanced Basic Meta-Analysis

Advanced Basic Meta-Analysis

Author: Brian Mullen

Publisher: Lawrence Erlbaum Assoc Incorporated

Published: 1989-11-01

Total Pages: 169

ISBN-13: 9781563211331

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In response to the growing emphasis on precision in the summarization and integration of research literature, "Advanced BASIC Meta-Analysis" presents an overview of strategies, techniques, and procedures used in meta-analysis. The book and software provide an integrated and comprehensive combination of meta-analytic tools for the statistical integration of independent study results. "Advanced BASIC Meta-Analysis" has three distinct goals: * to provide a clear and user-friendly introduction to the procedures and rules of effective meta-analytic integration; * to present the implicit assumptions and strategies that guide successful meta-analytic integrations; and * to develop a meta-analytic database management system that allows users to create, modify, and update a database, including the relevant statistical information and predictors, for a given research domain. The companion software system allows users to perform a full complement of meta-analytic statistical functions with the speed and flexibility of a database management system. It can also construct a wide array of meta-analytic graphic displays. This text and software package serves as a useful introduction to the quantitative assessment of research domains for those new to meta-analyses. It is also a valuable sourcebook for those who have already conducted meta-analyses.


Book Synopsis Advanced Basic Meta-Analysis by : Brian Mullen

Download or read book Advanced Basic Meta-Analysis written by Brian Mullen and published by Lawrence Erlbaum Assoc Incorporated. This book was released on 1989-11-01 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the growing emphasis on precision in the summarization and integration of research literature, "Advanced BASIC Meta-Analysis" presents an overview of strategies, techniques, and procedures used in meta-analysis. The book and software provide an integrated and comprehensive combination of meta-analytic tools for the statistical integration of independent study results. "Advanced BASIC Meta-Analysis" has three distinct goals: * to provide a clear and user-friendly introduction to the procedures and rules of effective meta-analytic integration; * to present the implicit assumptions and strategies that guide successful meta-analytic integrations; and * to develop a meta-analytic database management system that allows users to create, modify, and update a database, including the relevant statistical information and predictors, for a given research domain. The companion software system allows users to perform a full complement of meta-analytic statistical functions with the speed and flexibility of a database management system. It can also construct a wide array of meta-analytic graphic displays. This text and software package serves as a useful introduction to the quantitative assessment of research domains for those new to meta-analyses. It is also a valuable sourcebook for those who have already conducted meta-analyses.

Advances in Meta-Analysis

Advances in Meta-Analysis

Author: Terri Pigott

Publisher: Springer Science & Business Media

Published: 2012-01-31

Total Pages: 166

ISBN-13: 1461422779

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The subject of the book is advanced statistical analyses for quantitative research synthesis (meta-analysis), and selected practical issues relating to research synthesis that are not covered in detail in the many existing introductory books on research synthesis (or meta-analysis). Complex statistical issues are arising more frequently as the primary research that is summarized in quantitative syntheses itself becomes more complex, and as researchers who are conducting meta-analyses become more ambitious in the questions they wish to address. Also as researchers have gained more experience in conducting research syntheses, several key issues have persisted and now appear fundamental to the enterprise of summarizing research. Specifically the book describes multivariate analyses for several indices commonly used in meta-analysis (e.g., correlations, effect sizes, proportions and/or odds ratios), will outline how to do power analysis for meta-analysis (again for each of the different kinds of study outcome indices), and examines issues around research quality and research design and their roles in synthesis. For each of the statistical topics we will examine the different possible statistical models (i.e., fixed, random, and mixed models) that could be adopted by a researcher. In dealing with the issues of study quality and research design it covers a number of specific topics that are of broad concern to research synthesists. In many fields a current issue is how to make sense of results when studies using several different designs appear in a research literature (e.g., Morris & Deshon, 1997, 2002). In education and other social sciences a critical aspect of this issue is how one might incorporate qualitative (e.g., case study) research within a synthesis. In medicine, related issues concern whether and how to summarize observational studies, and whether they should be combined with randomized controlled trials (or even if they should be combined at all). For each topic, included is a worked example (e.g., for the statistical analyses) and/or a detailed description of a published research synthesis that deals with the practical (non-statistical) issues covered.


Book Synopsis Advances in Meta-Analysis by : Terri Pigott

Download or read book Advances in Meta-Analysis written by Terri Pigott and published by Springer Science & Business Media. This book was released on 2012-01-31 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of the book is advanced statistical analyses for quantitative research synthesis (meta-analysis), and selected practical issues relating to research synthesis that are not covered in detail in the many existing introductory books on research synthesis (or meta-analysis). Complex statistical issues are arising more frequently as the primary research that is summarized in quantitative syntheses itself becomes more complex, and as researchers who are conducting meta-analyses become more ambitious in the questions they wish to address. Also as researchers have gained more experience in conducting research syntheses, several key issues have persisted and now appear fundamental to the enterprise of summarizing research. Specifically the book describes multivariate analyses for several indices commonly used in meta-analysis (e.g., correlations, effect sizes, proportions and/or odds ratios), will outline how to do power analysis for meta-analysis (again for each of the different kinds of study outcome indices), and examines issues around research quality and research design and their roles in synthesis. For each of the statistical topics we will examine the different possible statistical models (i.e., fixed, random, and mixed models) that could be adopted by a researcher. In dealing with the issues of study quality and research design it covers a number of specific topics that are of broad concern to research synthesists. In many fields a current issue is how to make sense of results when studies using several different designs appear in a research literature (e.g., Morris & Deshon, 1997, 2002). In education and other social sciences a critical aspect of this issue is how one might incorporate qualitative (e.g., case study) research within a synthesis. In medicine, related issues concern whether and how to summarize observational studies, and whether they should be combined with randomized controlled trials (or even if they should be combined at all). For each topic, included is a worked example (e.g., for the statistical analyses) and/or a detailed description of a published research synthesis that deals with the practical (non-statistical) issues covered.

Doing Meta-Analysis with R

Doing Meta-Analysis with R

Author: Mathias Harrer

Publisher: CRC Press

Published: 2021-09-15

Total Pages: 500

ISBN-13: 1000435636

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Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book


Book Synopsis Doing Meta-Analysis with R by : Mathias Harrer

Download or read book Doing Meta-Analysis with R written by Mathias Harrer and published by CRC Press. This book was released on 2021-09-15 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book

Introduction to Meta-Analysis

Introduction to Meta-Analysis

Author: Michael Borenstein

Publisher: John Wiley & Sons

Published: 2011-08-24

Total Pages: 350

ISBN-13: 1119964377

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This book provides a clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies. Meta-analysis has become a critically important tool in fields as diverse as medicine, pharmacology, epidemiology, education, psychology, business, and ecology. Introduction to Meta-Analysis: Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Clarifies concepts using text and figures, followed by formulas and examples Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Features a web site with additional material and exercises A superb combination of lucid prose and informative graphics, written by four of the world’s leading experts on all aspects of meta-analysis. Borenstein, Hedges, Higgins, and Rothstein provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students, who used pre-publication versions of some of the chapters, raved about the clarity of the explanations and examples. David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics. The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice. Jesse A. Berlin, ScD Introduction to Meta-Analysis is an excellent resource for novices and experts alike. The book provides a clear and comprehensive presentation of all basic and most advanced approaches to meta-analysis. This book will be referenced for decades. Michael A. McDaniel, Professor of Human Resources and Organizational Behavior, Virginia Commonwealth University


Book Synopsis Introduction to Meta-Analysis by : Michael Borenstein

Download or read book Introduction to Meta-Analysis written by Michael Borenstein and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies. Meta-analysis has become a critically important tool in fields as diverse as medicine, pharmacology, epidemiology, education, psychology, business, and ecology. Introduction to Meta-Analysis: Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Clarifies concepts using text and figures, followed by formulas and examples Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Features a web site with additional material and exercises A superb combination of lucid prose and informative graphics, written by four of the world’s leading experts on all aspects of meta-analysis. Borenstein, Hedges, Higgins, and Rothstein provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students, who used pre-publication versions of some of the chapters, raved about the clarity of the explanations and examples. David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics. The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice. Jesse A. Berlin, ScD Introduction to Meta-Analysis is an excellent resource for novices and experts alike. The book provides a clear and comprehensive presentation of all basic and most advanced approaches to meta-analysis. This book will be referenced for decades. Michael A. McDaniel, Professor of Human Resources and Organizational Behavior, Virginia Commonwealth University

Cochrane Handbook for Systematic Reviews of Interventions

Cochrane Handbook for Systematic Reviews of Interventions

Author: Julian P. T. Higgins

Publisher: Wiley

Published: 2008-11-24

Total Pages: 672

ISBN-13: 9780470699515

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Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.


Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Meta-Analysis

Meta-Analysis

Author: Mike W.-L. Cheung

Publisher: John Wiley & Sons

Published: 2015-05-06

Total Pages: 401

ISBN-13: 1119993431

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Presents a novel approach to conducting meta-analysis using structural equation modeling. Structural equation modeling (SEM) and meta-analysis are two powerful statistical methods in the educational, social, behavioral, and medical sciences. They are often treated as two unrelated topics in the literature. This book presents a unified framework on analyzing meta-analytic data within the SEM framework, and illustrates how to conduct meta-analysis using the metaSEM package in the R statistical environment. Meta-Analysis: A Structural Equation Modeling Approach begins by introducing the importance of SEM and meta-analysis in answering research questions. Key ideas in meta-analysis and SEM are briefly reviewed, and various meta-analytic models are then introduced and linked to the SEM framework. Fixed-, random-, and mixed-effects models in univariate and multivariate meta-analyses, three-level meta-analysis, and meta-analytic structural equation modeling, are introduced. Advanced topics, such as using restricted maximum likelihood estimation method and handling missing covariates, are also covered. Readers will learn a single framework to apply both meta-analysis and SEM. Examples in R and in Mplus are included. This book will be a valuable resource for statistical and academic researchers and graduate students carrying out meta-analyses, and will also be useful to researchers and statisticians using SEM in biostatistics. Basic knowledge of either SEM or meta-analysis will be helpful in understanding the materials in this book.


Book Synopsis Meta-Analysis by : Mike W.-L. Cheung

Download or read book Meta-Analysis written by Mike W.-L. Cheung and published by John Wiley & Sons. This book was released on 2015-05-06 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a novel approach to conducting meta-analysis using structural equation modeling. Structural equation modeling (SEM) and meta-analysis are two powerful statistical methods in the educational, social, behavioral, and medical sciences. They are often treated as two unrelated topics in the literature. This book presents a unified framework on analyzing meta-analytic data within the SEM framework, and illustrates how to conduct meta-analysis using the metaSEM package in the R statistical environment. Meta-Analysis: A Structural Equation Modeling Approach begins by introducing the importance of SEM and meta-analysis in answering research questions. Key ideas in meta-analysis and SEM are briefly reviewed, and various meta-analytic models are then introduced and linked to the SEM framework. Fixed-, random-, and mixed-effects models in univariate and multivariate meta-analyses, three-level meta-analysis, and meta-analytic structural equation modeling, are introduced. Advanced topics, such as using restricted maximum likelihood estimation method and handling missing covariates, are also covered. Readers will learn a single framework to apply both meta-analysis and SEM. Examples in R and in Mplus are included. This book will be a valuable resource for statistical and academic researchers and graduate students carrying out meta-analyses, and will also be useful to researchers and statisticians using SEM in biostatistics. Basic knowledge of either SEM or meta-analysis will be helpful in understanding the materials in this book.

Advances in Meta-Analysis

Advances in Meta-Analysis

Author: Terri Pigott

Publisher: Springer Science & Business Media

Published: 2012-02-01

Total Pages: 166

ISBN-13: 1461422787

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The subject of the book is advanced statistical analyses for quantitative research synthesis (meta-analysis), and selected practical issues relating to research synthesis that are not covered in detail in the many existing introductory books on research synthesis (or meta-analysis). Complex statistical issues are arising more frequently as the primary research that is summarized in quantitative syntheses itself becomes more complex, and as researchers who are conducting meta-analyses become more ambitious in the questions they wish to address. Also as researchers have gained more experience in conducting research syntheses, several key issues have persisted and now appear fundamental to the enterprise of summarizing research. Specifically the book describes multivariate analyses for several indices commonly used in meta-analysis (e.g., correlations, effect sizes, proportions and/or odds ratios), will outline how to do power analysis for meta-analysis (again for each of the different kinds of study outcome indices), and examines issues around research quality and research design and their roles in synthesis. For each of the statistical topics we will examine the different possible statistical models (i.e., fixed, random, and mixed models) that could be adopted by a researcher. In dealing with the issues of study quality and research design it covers a number of specific topics that are of broad concern to research synthesists. In many fields a current issue is how to make sense of results when studies using several different designs appear in a research literature (e.g., Morris & Deshon, 1997, 2002). In education and other social sciences a critical aspect of this issue is how one might incorporate qualitative (e.g., case study) research within a synthesis. In medicine, related issues concern whether and how to summarize observational studies, and whether they should be combined with randomized controlled trials (or even if they should be combined at all). For each topic, included is a worked example (e.g., for the statistical analyses) and/or a detailed description of a published research synthesis that deals with the practical (non-statistical) issues covered.


Book Synopsis Advances in Meta-Analysis by : Terri Pigott

Download or read book Advances in Meta-Analysis written by Terri Pigott and published by Springer Science & Business Media. This book was released on 2012-02-01 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of the book is advanced statistical analyses for quantitative research synthesis (meta-analysis), and selected practical issues relating to research synthesis that are not covered in detail in the many existing introductory books on research synthesis (or meta-analysis). Complex statistical issues are arising more frequently as the primary research that is summarized in quantitative syntheses itself becomes more complex, and as researchers who are conducting meta-analyses become more ambitious in the questions they wish to address. Also as researchers have gained more experience in conducting research syntheses, several key issues have persisted and now appear fundamental to the enterprise of summarizing research. Specifically the book describes multivariate analyses for several indices commonly used in meta-analysis (e.g., correlations, effect sizes, proportions and/or odds ratios), will outline how to do power analysis for meta-analysis (again for each of the different kinds of study outcome indices), and examines issues around research quality and research design and their roles in synthesis. For each of the statistical topics we will examine the different possible statistical models (i.e., fixed, random, and mixed models) that could be adopted by a researcher. In dealing with the issues of study quality and research design it covers a number of specific topics that are of broad concern to research synthesists. In many fields a current issue is how to make sense of results when studies using several different designs appear in a research literature (e.g., Morris & Deshon, 1997, 2002). In education and other social sciences a critical aspect of this issue is how one might incorporate qualitative (e.g., case study) research within a synthesis. In medicine, related issues concern whether and how to summarize observational studies, and whether they should be combined with randomized controlled trials (or even if they should be combined at all). For each topic, included is a worked example (e.g., for the statistical analyses) and/or a detailed description of a published research synthesis that deals with the practical (non-statistical) issues covered.

Network Meta-Analysis for Decision-Making

Network Meta-Analysis for Decision-Making

Author: Sofia Dias

Publisher: John Wiley & Sons

Published: 2018-03-19

Total Pages: 484

ISBN-13: 1118647505

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A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is 'best'?" A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.


Book Synopsis Network Meta-Analysis for Decision-Making by : Sofia Dias

Download or read book Network Meta-Analysis for Decision-Making written by Sofia Dias and published by John Wiley & Sons. This book was released on 2018-03-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is 'best'?" A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.

Methods for Meta-Analysis in Medical Research

Methods for Meta-Analysis in Medical Research

Author: A. J. Sutton

Publisher: John Wiley & Sons

Published: 2000-12-19

Total Pages: 360

ISBN-13:

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With meta-analysis methods playing a crucial role in health research in recent years, this important and clearly-written book provides a much-needed survey of the field. Meta-analysis provides a framework for combining the results of several clinical trials and drawing inferences about the effectiveness of medical treatments. The move towards evidence-based health care and practice is underpinned by the use of meta-analysis. This book: * Provides a thorough criticism and an up-to-date survey of meta-analysis methods * Emphasises the practical approach, and illustrates the methods by numerous examples * Describes the use of Bayesian methods in meta-analysis * Includes discussion of appropriate software for each analysis * Includes numerous references to more advanced treatment of specialist topics * Refers to software code used in the examples available on the authors' Web site Practising statisticians, statistically-minded clinicians and health research professionals will benefit greatly from the clear presentation and numerous examples. Medical researchers will grasp the basic principles of meta-analysis, and learn how to apply the various methods.


Book Synopsis Methods for Meta-Analysis in Medical Research by : A. J. Sutton

Download or read book Methods for Meta-Analysis in Medical Research written by A. J. Sutton and published by John Wiley & Sons. This book was released on 2000-12-19 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: With meta-analysis methods playing a crucial role in health research in recent years, this important and clearly-written book provides a much-needed survey of the field. Meta-analysis provides a framework for combining the results of several clinical trials and drawing inferences about the effectiveness of medical treatments. The move towards evidence-based health care and practice is underpinned by the use of meta-analysis. This book: * Provides a thorough criticism and an up-to-date survey of meta-analysis methods * Emphasises the practical approach, and illustrates the methods by numerous examples * Describes the use of Bayesian methods in meta-analysis * Includes discussion of appropriate software for each analysis * Includes numerous references to more advanced treatment of specialist topics * Refers to software code used in the examples available on the authors' Web site Practising statisticians, statistically-minded clinicians and health research professionals will benefit greatly from the clear presentation and numerous examples. Medical researchers will grasp the basic principles of meta-analysis, and learn how to apply the various methods.