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Advances in Rapid Sex-Steroid Action

Author: Gabriella Castoria

Publisher: Springer Science & Business Media

Published: 2011-12-15

Total Pages: 271

ISBN-13: 1461417643

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Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.

Book Synopsis Advances in Rapid Sex-Steroid Action by : Gabriella Castoria

Download or read book Advances in Rapid Sex-Steroid Action written by Gabriella Castoria and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.

Advances in Rapid Sex-Steroid Action

Author: Gabriella Castoria

Publisher: Springer

Published: 2011-12-14

Total Pages: 270

ISBN-13: 9781461417651

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Book Synopsis Advances in Rapid Sex-Steroid Action by : Gabriella Castoria

Download or read book Advances in Rapid Sex-Steroid Action written by Gabriella Castoria and published by Springer. This book was released on 2011-12-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.

Neurobiological Effects of Sex Steroid Hormones

Author: Paul E. Micevych

Publisher: Cambridge University Press

Published: 1995-05-26

Total Pages: 468

ISBN-13: 0521454301

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Neurobiological Effects of Sex Steroid Hormones describes the neurobiological basis for the understanding of how sex steroid hormones, oestrogen and testosterone, interact with parts of the brain. The contributors have all made significant advances in the understanding of how these steroids regulate neural function, and how this activity is translated into reproductive behaviours necessary for the propagation of the species. This book covers a broad range of topics, extending from the molecular and cellular processes, through the action of steroids on neurotransmission, all the way to defining the brain circuitry involved in both male and female behaviour. This volume presents a snapshot of the rapidly advancing field of reproductive neuroendocrinology by the investigators who are most intimately involved with the discoveries.

Book Synopsis Neurobiological Effects of Sex Steroid Hormones by : Paul E. Micevych

Download or read book Neurobiological Effects of Sex Steroid Hormones written by Paul E. Micevych and published by Cambridge University Press. This book was released on 1995-05-26 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiological Effects of Sex Steroid Hormones describes the neurobiological basis for the understanding of how sex steroid hormones, oestrogen and testosterone, interact with parts of the brain. The contributors have all made significant advances in the understanding of how these steroids regulate neural function, and how this activity is translated into reproductive behaviours necessary for the propagation of the species. This book covers a broad range of topics, extending from the molecular and cellular processes, through the action of steroids on neurotransmission, all the way to defining the brain circuitry involved in both male and female behaviour. This volume presents a snapshot of the rapidly advancing field of reproductive neuroendocrinology by the investigators who are most intimately involved with the discoveries.

Sex Steroids

Author: Scott M. Kahn

Publisher: BoD – Books on Demand

Published: 2012-01-27

Total Pages: 346

ISBN-13: 953307857X

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This book, entitled "Sex Steroids", features a valuable collection of reviews and research articles written by experts in signal transduction, cellular biology, diseases and disorders. "Sex Steroids" is comprised of four sections, "The Biology of Sex Steroids", "Sex Steroids, Memory, and the Brain", "Sex Steroids and the Immune Response", and "Therapy"; individual chapters address a broad range of recognized and predicted functions and applications of sex steroids. "Sex Steroids" is intended to provide seasoned veterans as well as newcomers to this area of research with informative, resourceful, and provocative insights. Readers of "Sex Steroids" should emerge with an appreciation and understanding of the multitude and complexity of biologic processes attributed to these important hormones, and possible future directions of research in this fascinating and ever evolving field.

Book Synopsis Sex Steroids by : Scott M. Kahn

Download or read book Sex Steroids written by Scott M. Kahn and published by BoD – Books on Demand. This book was released on 2012-01-27 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, entitled "Sex Steroids", features a valuable collection of reviews and research articles written by experts in signal transduction, cellular biology, diseases and disorders. "Sex Steroids" is comprised of four sections, "The Biology of Sex Steroids", "Sex Steroids, Memory, and the Brain", "Sex Steroids and the Immune Response", and "Therapy"; individual chapters address a broad range of recognized and predicted functions and applications of sex steroids. "Sex Steroids" is intended to provide seasoned veterans as well as newcomers to this area of research with informative, resourceful, and provocative insights. Readers of "Sex Steroids" should emerge with an appreciation and understanding of the multitude and complexity of biologic processes attributed to these important hormones, and possible future directions of research in this fascinating and ever evolving field.

Advanced Exercise Endocrinology

Author: Katarina T. Borer

Publisher: Human Kinetics

Published: 2013

Total Pages: 274

ISBN-13: 073607516X

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Advanced Exercise Endocrinology provides a comprehensive examination of the relationship between physical activity and hormone function. It is an essential reference for exercise physiologists and physiotherapists researching the connections between exercise, hormone function, and health.

Book Synopsis Advanced Exercise Endocrinology by : Katarina T. Borer

Download or read book Advanced Exercise Endocrinology written by Katarina T. Borer and published by Human Kinetics. This book was released on 2013 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Exercise Endocrinology provides a comprehensive examination of the relationship between physical activity and hormone function. It is an essential reference for exercise physiologists and physiotherapists researching the connections between exercise, hormone function, and health.

Sex Hormones in Neurodegenerative Processes and Diseases

Author: Gorazd Drevensek

Publisher: BoD – Books on Demand

Published: 2018-05-02

Total Pages: 360

ISBN-13: 1789230144

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The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.

Book Synopsis Sex Hormones in Neurodegenerative Processes and Diseases by : Gorazd Drevensek

Download or read book Sex Hormones in Neurodegenerative Processes and Diseases written by Gorazd Drevensek and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.

Progress in the Management of the Menopause: Proceedings of the 8th International Congress on the Menopause, Sydney, Australia

Author: B.G. Wren

Publisher: CRC Press

Published: 2020-07-26

Total Pages: 508

ISBN-13: 1000102211

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This is a comprehensive, up-to-date, authoritative research text and clinical reference work the menopause. It contains over 90 contributions covering every conceivable topic in the management of the menopause in women and related issues in the aging male. The book contains many illustrations and a wealth of references.

Book Synopsis Progress in the Management of the Menopause: Proceedings of the 8th International Congress on the Menopause, Sydney, Australia by : B.G. Wren

Download or read book Progress in the Management of the Menopause: Proceedings of the 8th International Congress on the Menopause, Sydney, Australia written by B.G. Wren and published by CRC Press. This book was released on 2020-07-26 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive, up-to-date, authoritative research text and clinical reference work the menopause. It contains over 90 contributions covering every conceivable topic in the management of the menopause in women and related issues in the aging male. The book contains many illustrations and a wealth of references.

Steroid Hormone Action

Author: Malcolm G. Parker

Publisher: IRL Press

Published: 1993

Total Pages: 242

ISBN-13:

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This volume provides a detailed overview of the mechanisms by which steroid hormones regulate gene activity in target cells. It should be of interest to molecular biologists, endocrinologists, pharmacologists and clinicians interested in gene regulation hormones and steroid antagonists.

Book Synopsis Steroid Hormone Action by : Malcolm G. Parker

Download or read book Steroid Hormone Action written by Malcolm G. Parker and published by IRL Press. This book was released on 1993 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a detailed overview of the mechanisms by which steroid hormones regulate gene activity in target cells. It should be of interest to molecular biologists, endocrinologists, pharmacologists and clinicians interested in gene regulation hormones and steroid antagonists.

Progress in Molecular Biology and Translational Science

Author:

Publisher: Academic Press

Published: 2018-11-20

Total Pages: 188

ISBN-13: 0128162384

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Progress in Molecular Biology and Translational Science, Volume 160 provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Clinical Drugs in the Environment, Group I Intron Trans-Splicing, Adult Stem Cells on Regenerative Therapy, CRISPR in Animals and Animal Models, The Role of 3’–5’Exoribonucleases in RNA Degradation, and more. Comprises 15-20 chapters, which allows substantial coverage on a given topic Contains ample use of tables, diagrams, schemata, and color figures to enhance the reader's ability to rapidly grasp the information provided in each chapter Provides a comprehensive guide to the latest information available on prions, viruses, bacteria, and eukaryotes

Book Synopsis Progress in Molecular Biology and Translational Science by :

Download or read book Progress in Molecular Biology and Translational Science written by and published by Academic Press. This book was released on 2018-11-20 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Molecular Biology and Translational Science, Volume 160 provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Clinical Drugs in the Environment, Group I Intron Trans-Splicing, Adult Stem Cells on Regenerative Therapy, CRISPR in Animals and Animal Models, The Role of 3’–5’Exoribonucleases in RNA Degradation, and more. Comprises 15-20 chapters, which allows substantial coverage on a given topic Contains ample use of tables, diagrams, schemata, and color figures to enhance the reader's ability to rapidly grasp the information provided in each chapter Provides a comprehensive guide to the latest information available on prions, viruses, bacteria, and eukaryotes

Diagnosis and Management of Ovarian Disorders

Author: Albert Altchek

Publisher: Elsevier

Published: 2003-09-04

Total Pages: 595

ISBN-13: 008049451X

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This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine

Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine