Adverse Cutaneous Drug Reactions to Cardiovascular Drugs

Adverse Cutaneous Drug Reactions to Cardiovascular Drugs

Author: Esen Özkaya

Publisher: Springer

Published: 2014-11-15

Total Pages: 268

ISBN-13: 1447165365

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Adverse cutaneous drug reactions (ACDR) are among the most frequent events in patients receiving drug therapy. Cardiovascular (CV) drugs are an important group of drugs with potential risk of developing ACDR especially in elderly as marketing of more new drugs and their prescription continue to increase. However, like with most other drugs the exact incidence of cutaneous side effects from CV drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable designation of a certain drug as the cause of a certain type of reaction can rarely be made. Apart from the well-known angioedema/urticaria from ACE inhibitors, lichen planus / lichenoid reaction from beta adrenergic blockers and photosensitivity from thiazid diuretics, ACDR from CV drugs might be seen in a wide spectrum extending to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis or drug hypersensitivity syndrome. In this comprehensive review, the reported types of ACDR to CV drugs will be discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis.


Book Synopsis Adverse Cutaneous Drug Reactions to Cardiovascular Drugs by : Esen Özkaya

Download or read book Adverse Cutaneous Drug Reactions to Cardiovascular Drugs written by Esen Özkaya and published by Springer. This book was released on 2014-11-15 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse cutaneous drug reactions (ACDR) are among the most frequent events in patients receiving drug therapy. Cardiovascular (CV) drugs are an important group of drugs with potential risk of developing ACDR especially in elderly as marketing of more new drugs and their prescription continue to increase. However, like with most other drugs the exact incidence of cutaneous side effects from CV drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable designation of a certain drug as the cause of a certain type of reaction can rarely be made. Apart from the well-known angioedema/urticaria from ACE inhibitors, lichen planus / lichenoid reaction from beta adrenergic blockers and photosensitivity from thiazid diuretics, ACDR from CV drugs might be seen in a wide spectrum extending to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis or drug hypersensitivity syndrome. In this comprehensive review, the reported types of ACDR to CV drugs will be discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis.

Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions

Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions

Author: Neil H. Shear

Publisher: Springer

Published: 2018-10-19

Total Pages: 314

ISBN-13: 9811314896

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This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.


Book Synopsis Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions by : Neil H. Shear

Download or read book Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions written by Neil H. Shear and published by Springer. This book was released on 2018-10-19 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.

Adverse Cutaneous Drug Eruptions

Adverse Cutaneous Drug Eruptions

Author: Lars E. French

Publisher: Karger Medical and Scientific Publishers

Published: 2012

Total Pages: 255

ISBN-13: 3805599706

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An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.


Book Synopsis Adverse Cutaneous Drug Eruptions by : Lars E. French

Download or read book Adverse Cutaneous Drug Eruptions written by Lars E. French and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.

Adverse Drug Reactions and the Skin

Adverse Drug Reactions and the Skin

Author: Stephen Breathnach

Publisher: Wiley-Blackwell

Published: 1992-11-10

Total Pages: 408

ISBN-13: 9780632033492

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Adverse Drug Reactions and the Skin is a thoroughly modern and comprehensive text/atlas covering the side effects to the skin, from medications, and the dermatological and other internal adverse manifestations of medications used by dermatologists. Illustrated in full color, this major new work will enjoy wide use across a broad cross-section of the medical profession. This volume is divided into three major sections. The first deals with the incidence and mechanisms of drug adverse reactions. The second section discusses reaction patterns that are recognized as characteristic of cutaneous drug reactions to particular medications. The reaction patterns are fully discussed and the text is fully supported by wide use of full-color illustrations. Lists of the drugs most commonly implicated in the causation of these reactions are also included. The final section includes the drugs reported to have caused skin side-effects, in a systematic listing by therapeutic groups. This listing includes dermatological preparations. Thus, the reader is able to research information on skin changes potentially caused by a given drug, and also to determine which drugs cause a given clinical reaction pattern.


Book Synopsis Adverse Drug Reactions and the Skin by : Stephen Breathnach

Download or read book Adverse Drug Reactions and the Skin written by Stephen Breathnach and published by Wiley-Blackwell. This book was released on 1992-11-10 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Drug Reactions and the Skin is a thoroughly modern and comprehensive text/atlas covering the side effects to the skin, from medications, and the dermatological and other internal adverse manifestations of medications used by dermatologists. Illustrated in full color, this major new work will enjoy wide use across a broad cross-section of the medical profession. This volume is divided into three major sections. The first deals with the incidence and mechanisms of drug adverse reactions. The second section discusses reaction patterns that are recognized as characteristic of cutaneous drug reactions to particular medications. The reaction patterns are fully discussed and the text is fully supported by wide use of full-color illustrations. Lists of the drugs most commonly implicated in the causation of these reactions are also included. The final section includes the drugs reported to have caused skin side-effects, in a systematic listing by therapeutic groups. This listing includes dermatological preparations. Thus, the reader is able to research information on skin changes potentially caused by a given drug, and also to determine which drugs cause a given clinical reaction pattern.

Adverse Cutaneous Reactions to Medication

Adverse Cutaneous Reactions to Medication

Author: Sanford M. Goldstein

Publisher: Lippincott Williams & Wilkins

Published: 1996

Total Pages: 164

ISBN-13:

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Book Synopsis Adverse Cutaneous Reactions to Medication by : Sanford M. Goldstein

Download or read book Adverse Cutaneous Reactions to Medication written by Sanford M. Goldstein and published by Lippincott Williams & Wilkins. This book was released on 1996 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cutaneous Drug Eruptions

Cutaneous Drug Eruptions

Author: John C. Hall

Publisher: Springer

Published: 2015-08-21

Total Pages: 463

ISBN-13: 1447167295

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​The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings, and can result in morbidity and even mortality. This book is unique in its approach to this problem. This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist. Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy. True incidences of drug reactions are not available. For general discussion, the rule of 3% can be applied with reasonable assuredness. Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction. Approximately 3% of these reactions are considered severe. Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction. Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.


Book Synopsis Cutaneous Drug Eruptions by : John C. Hall

Download or read book Cutaneous Drug Eruptions written by John C. Hall and published by Springer. This book was released on 2015-08-21 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings, and can result in morbidity and even mortality. This book is unique in its approach to this problem. This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist. Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy. True incidences of drug reactions are not available. For general discussion, the rule of 3% can be applied with reasonable assuredness. Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction. Approximately 3% of these reactions are considered severe. Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction. Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.

Skin Reactions to Drugs

Skin Reactions to Drugs

Author: Kirsti Kauppinen

Publisher: CRC-Press

Published: 1998-06-01

Total Pages: 178

ISBN-13: 9780849383762

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Emphasising the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions, this book discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world. 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers.


Book Synopsis Skin Reactions to Drugs by : Kirsti Kauppinen

Download or read book Skin Reactions to Drugs written by Kirsti Kauppinen and published by CRC-Press. This book was released on 1998-06-01 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasising the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions, this book discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world. 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers.

Skin and the Heart

Skin and the Heart

Author: Carmen Salavastru

Publisher: Springer Nature

Published: 2021-03-10

Total Pages: 494

ISBN-13: 3030547795

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This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment. Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa. Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.


Book Synopsis Skin and the Heart by : Carmen Salavastru

Download or read book Skin and the Heart written by Carmen Salavastru and published by Springer Nature. This book was released on 2021-03-10 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment. Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa. Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.

Cutaneous Adverse Drug Reactions

Cutaneous Adverse Drug Reactions

Author: Heng Leong Chan

Publisher:

Published: 2000

Total Pages: 140

ISBN-13: 9789814045513

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Book Synopsis Cutaneous Adverse Drug Reactions by : Heng Leong Chan

Download or read book Cutaneous Adverse Drug Reactions written by Heng Leong Chan and published by . This book was released on 2000 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacogenetics to Avoid Adverse Drug Reactions

Pharmacogenetics to Avoid Adverse Drug Reactions

Author: Luis A. Fernandez

Publisher:

Published: 2022-02-22

Total Pages: 220

ISBN-13: 9783036533445

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Book Synopsis Pharmacogenetics to Avoid Adverse Drug Reactions by : Luis A. Fernandez

Download or read book Pharmacogenetics to Avoid Adverse Drug Reactions written by Luis A. Fernandez and published by . This book was released on 2022-02-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: