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This book consists of 11 chapters, divided into four parts. The chapters are written by experts in the field of aflatoxins. Select topics are presented here to provide a snapshot of current understanding of the occurrence and metabolism of aflatoxin B1, the contamination, exposure, and detection of aflatoxin B1, and the toxicological effects and detoxification of aflatoxin. The book is intended for students and scientists working in the field of aflatoxins.
Book Synopsis Aflatoxin B1 Occurrence, Detection and Toxicological Effects by :
Download or read book Aflatoxin B1 Occurrence, Detection and Toxicological Effects written by and published by BoD – Books on Demand. This book was released on 2020-06-03 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of 11 chapters, divided into four parts. The chapters are written by experts in the field of aflatoxins. Select topics are presented here to provide a snapshot of current understanding of the occurrence and metabolism of aflatoxin B1, the contamination, exposure, and detection of aflatoxin B1, and the toxicological effects and detoxification of aflatoxin. The book is intended for students and scientists working in the field of aflatoxins.
Aflatoxins are a group of highly toxic and carcinogenic substances that occur naturally and can be found in food substances. Aflatoxins are secondary metabolites of certain strains of fungi Aspergillus flavus and Aspergillus parasiticus as well as the less common Aspergillus nomius. Aflatoxins B1, B2, G1, and G2 are the most important members, which can be categorized into two groups according to chemical structure. As a result of the adverse health effects of mycotoxins, their levels have been strictly regulated, especially in food and feed samples. Therefore, their accurate identification and determination remain a herculean task due to their presence in the complex food matrix. The great public concern and the strict legislation incited the development of sensitive analytical methods that are discussed in this book.
Book Synopsis Aflatoxins by : Lukman Abdulra`uf
Download or read book Aflatoxins written by Lukman Abdulra`uf and published by BoD – Books on Demand. This book was released on 2022-02-09 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aflatoxins are a group of highly toxic and carcinogenic substances that occur naturally and can be found in food substances. Aflatoxins are secondary metabolites of certain strains of fungi Aspergillus flavus and Aspergillus parasiticus as well as the less common Aspergillus nomius. Aflatoxins B1, B2, G1, and G2 are the most important members, which can be categorized into two groups according to chemical structure. As a result of the adverse health effects of mycotoxins, their levels have been strictly regulated, especially in food and feed samples. Therefore, their accurate identification and determination remain a herculean task due to their presence in the complex food matrix. The great public concern and the strict legislation incited the development of sensitive analytical methods that are discussed in this book.
Progress in understanding the biology of Aspergillus has greatly improved with the new techniques in genome sequencing and the developed molecular tools that enable rapid genetic analysis of individual genes. Particularly, the genetics of aflatoxin synthesis is regarded as a model to gain insight into fungal secondary metabolism. This compilation discusses topics that include the prevalence of aflatoxin B1 in cereals; contamination exposure, toxicology and control of aflatoxins in food and feed; immunosuppressive actions of aflatoxin; hazards and regulations; toxicological effects, risk assessment and legislation for aflatoxins; and the threat aflatoxins have on the economy and health.
Book Synopsis Aflatoxins by : Adina G. Faulkner
Download or read book Aflatoxins written by Adina G. Faulkner and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in understanding the biology of Aspergillus has greatly improved with the new techniques in genome sequencing and the developed molecular tools that enable rapid genetic analysis of individual genes. Particularly, the genetics of aflatoxin synthesis is regarded as a model to gain insight into fungal secondary metabolism. This compilation discusses topics that include the prevalence of aflatoxin B1 in cereals; contamination exposure, toxicology and control of aflatoxins in food and feed; immunosuppressive actions of aflatoxin; hazards and regulations; toxicological effects, risk assessment and legislation for aflatoxins; and the threat aflatoxins have on the economy and health.
Aflatoxins are a group of highly toxic and carcinogenic substances, which occur naturally, and can be found in food substances. Aflatoxins are secondary metabolites of certain strains of the fungi Aspergillus flavus and A. parasiticus and the less common A. nomius. Aflatoxins B1, B2, G1, and G2 are the most important members, which can be categorized into two groups according to the chemical structure. As a result of the adverse health effects of mycotoxins, their levels have been strictly regulated especially in food and feed samples. Therefore, their accurate identification and determination remain a Herculean task due to their presence in complex food matrices. The great public concern and the strict legislation incited the development of reliable, specific, selective, and sensitive analytical methods for pesticide monitoring that are discussed in this book.
Book Synopsis Aflatoxin by : Lukman Abdulra'Uf
Download or read book Aflatoxin written by Lukman Abdulra'Uf and published by BoD – Books on Demand. This book was released on 2017-08-30 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aflatoxins are a group of highly toxic and carcinogenic substances, which occur naturally, and can be found in food substances. Aflatoxins are secondary metabolites of certain strains of the fungi Aspergillus flavus and A. parasiticus and the less common A. nomius. Aflatoxins B1, B2, G1, and G2 are the most important members, which can be categorized into two groups according to the chemical structure. As a result of the adverse health effects of mycotoxins, their levels have been strictly regulated especially in food and feed samples. Therefore, their accurate identification and determination remain a Herculean task due to their presence in complex food matrices. The great public concern and the strict legislation incited the development of reliable, specific, selective, and sensitive analytical methods for pesticide monitoring that are discussed in this book.
This Edited Volume Mycotoxins - Impact and Management Strategies is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of Mycotoxicology. The book comprises of single chapters authored by various researchers and edited by an expert active in this research area. This book is divided into three sections. Section 1 consists of one chapter that gives an overview of the socioeconomic impact of mycotoxins. Section 2 has five chapters that address the prevention and control of aflatoxins both at pre- and post-harvest stages. Section 3 has two chapters that deal with health impact and control in the poultry industry. This publication aims at providing a thorough overview of the latest research efforts in the field and opens new possible research paths for further novel developments in addressing the problem of mycotoxins.
Book Synopsis Mycotoxins by : Patrick Berka Njobeh
Download or read book Mycotoxins written by Patrick Berka Njobeh and published by BoD – Books on Demand. This book was released on 2019-08-28 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Edited Volume Mycotoxins - Impact and Management Strategies is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of Mycotoxicology. The book comprises of single chapters authored by various researchers and edited by an expert active in this research area. This book is divided into three sections. Section 1 consists of one chapter that gives an overview of the socioeconomic impact of mycotoxins. Section 2 has five chapters that address the prevention and control of aflatoxins both at pre- and post-harvest stages. Section 3 has two chapters that deal with health impact and control in the poultry industry. This publication aims at providing a thorough overview of the latest research efforts in the field and opens new possible research paths for further novel developments in addressing the problem of mycotoxins.
This book is broadly divided into five sections and 17 chapters, highlighting recent advances in aflatoxin research from epidemiology to molecular genomics and control measures, biocontrol approaches, modern analytical techniques, economic concerns and underlying mechanisms of contamination processes. This book will update readers on several cutting-edge aspects of aflatoxins research with useful up-to-date information for mycologists, toxicologists, microbiologists, agriculture scientists, plant pathologists and pharmacologists, who may be interest to understanding of the impact, significance and recent advances within the field of of aflatoxins with a focus on control strategy.
Book Synopsis Aflatoxins by : Mehdi Razzaghi-Abyaneh
Download or read book Aflatoxins written by Mehdi Razzaghi-Abyaneh and published by BoD – Books on Demand. This book was released on 2013-01-23 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is broadly divided into five sections and 17 chapters, highlighting recent advances in aflatoxin research from epidemiology to molecular genomics and control measures, biocontrol approaches, modern analytical techniques, economic concerns and underlying mechanisms of contamination processes. This book will update readers on several cutting-edge aspects of aflatoxins research with useful up-to-date information for mycologists, toxicologists, microbiologists, agriculture scientists, plant pathologists and pharmacologists, who may be interest to understanding of the impact, significance and recent advances within the field of of aflatoxins with a focus on control strategy.
Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.
Book Synopsis Biological Toxins and Bioterrorism by : P. Gopalakrishnakone
Download or read book Biological Toxins and Bioterrorism written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-01-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.
Mycotoxins are the metabolites of fungus and are reported to contaminate nearly 25% of the food produced worldwide. The mycotoxins of most significance are the aflatoxins due to their severe health implications and their prevalence in food commodities on a larger scale. Aflatoxins are produced by certain species of fungi the most prominent among which are Aspergillus flavus, A. parasiticus and A. nominous. Food commodities of African and South Asian countries are especially reported to have aflatoxins well beyond the allowable limits but due to the global trade of food commodities developed countries are also prone towards the perils of aflatoxins. Moreover, climate changes may have a substantial impact on the distribution and global prevalence of aflatoxins in the near future. The International Agency for Research on Cancer (IARC) has classified the aflatoxins as group 1 category carcinogen. Aflatoxins are also reported as teratogenic, mutagenic, growth retardant, immunosuppressant and may also cause nervous system and reproductive system disorders. Preventive approaches involving good manufacturing from “farm to fork” are the major focus of the current food industry. The aim of our book is to provide readers with the most recent data and up-to-date studies from aflatoxins research, with specific focuses on (i) the impact of aflatoxins on human health, (ii) new approaches by the researchers from different parts of the world to degrade aflatoxins and (iii) potential preventive approaches that can significantly lessen the burden of aflatoxins in food products
Book Synopsis Aflatoxins in Food by : Khalid Rehman Hakeem
Download or read book Aflatoxins in Food written by Khalid Rehman Hakeem and published by Springer Nature. This book was released on 2022-01-13 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins are the metabolites of fungus and are reported to contaminate nearly 25% of the food produced worldwide. The mycotoxins of most significance are the aflatoxins due to their severe health implications and their prevalence in food commodities on a larger scale. Aflatoxins are produced by certain species of fungi the most prominent among which are Aspergillus flavus, A. parasiticus and A. nominous. Food commodities of African and South Asian countries are especially reported to have aflatoxins well beyond the allowable limits but due to the global trade of food commodities developed countries are also prone towards the perils of aflatoxins. Moreover, climate changes may have a substantial impact on the distribution and global prevalence of aflatoxins in the near future. The International Agency for Research on Cancer (IARC) has classified the aflatoxins as group 1 category carcinogen. Aflatoxins are also reported as teratogenic, mutagenic, growth retardant, immunosuppressant and may also cause nervous system and reproductive system disorders. Preventive approaches involving good manufacturing from “farm to fork” are the major focus of the current food industry. The aim of our book is to provide readers with the most recent data and up-to-date studies from aflatoxins research, with specific focuses on (i) the impact of aflatoxins on human health, (ii) new approaches by the researchers from different parts of the world to degrade aflatoxins and (iii) potential preventive approaches that can significantly lessen the burden of aflatoxins in food products
Abstract: Mycotoxins are natural toxins produced by fungus. These toxins are food and feed contaminants inducing diverse toxicological effects on human and animal health that may affect different organs. These adverse effects may be hepatotoxic, nephrotoxic and neurotoxic; these effects may be acute or chronic implying that even traces amount of mycotoxins, may accumulate over time and become problematic. The occurrence of mycotoxins in food and feed are thus an issue of critical importance and is of main concern worldwide. Among the efforts that are being made to limits mycotoxins occurrence in food are the laws and regulations on their permissible limits. For instance, the permissible limits of Aflatoxins in peanuts are 4 ng/g for total aflatoxins and 2 ng/g for aflatoxin B1. These limits and regulations are based on human risk assessment studies, data about the occurrence of mycotoxins in various commodities, and the availability of sensitive and accurate analytical methods for their determination. In this work we developed a rapid, selective, sensitive, accurate and validated method for the simultaneous quantification of aflatoxins using LC-ESI-MS/MS. The developed method was applied on different sample matrices; peanuts (n = 45), lentils (n = 10), beans (n = 3), and wheat (n =2). The first ever reported data on the occurrence and levels of aflatoxins in peanuts in Greater Cairo are presented. The results presented here show that the investigated peanuts samples from 5 different regions in Greater Cairo contain mean concentrations of total aflatoxin ranging from 16.69 to 101.93 ng/g which are 4 to 25.5 times higher than the permissible limits set by the European Union and FDA.
Book Synopsis Mycotoxins Detection in Grains and Nuts Using LC – MS/MS by : Rahma Ali Hassan Abubakr
Download or read book Mycotoxins Detection in Grains and Nuts Using LC – MS/MS written by Rahma Ali Hassan Abubakr and published by . This book was released on 2017 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Mycotoxins are natural toxins produced by fungus. These toxins are food and feed contaminants inducing diverse toxicological effects on human and animal health that may affect different organs. These adverse effects may be hepatotoxic, nephrotoxic and neurotoxic; these effects may be acute or chronic implying that even traces amount of mycotoxins, may accumulate over time and become problematic. The occurrence of mycotoxins in food and feed are thus an issue of critical importance and is of main concern worldwide. Among the efforts that are being made to limits mycotoxins occurrence in food are the laws and regulations on their permissible limits. For instance, the permissible limits of Aflatoxins in peanuts are 4 ng/g for total aflatoxins and 2 ng/g for aflatoxin B1. These limits and regulations are based on human risk assessment studies, data about the occurrence of mycotoxins in various commodities, and the availability of sensitive and accurate analytical methods for their determination. In this work we developed a rapid, selective, sensitive, accurate and validated method for the simultaneous quantification of aflatoxins using LC-ESI-MS/MS. The developed method was applied on different sample matrices; peanuts (n = 45), lentils (n = 10), beans (n = 3), and wheat (n =2). The first ever reported data on the occurrence and levels of aflatoxins in peanuts in Greater Cairo are presented. The results presented here show that the investigated peanuts samples from 5 different regions in Greater Cairo contain mean concentrations of total aflatoxin ranging from 16.69 to 101.93 ng/g which are 4 to 25.5 times higher than the permissible limits set by the European Union and FDA.
Aflatoxins, natural fungal toxins found in foods and animal feeds, have great public health significance. This book presents the basic and applied toxicology of aflatoxins, including analytical identification, agricultural and veterinary implications, toxicology and carcinogenesis in humans, and economic and regulatory problems associated with aflatoxin contamination and control. Molecular mechanisms of aflatoxin toxicity Analytical issues in sampling and analysis Regulatory and economic issues associated with aflatoxin contamination of food and feed Presentation of human and animal toxicology, veterinary, and agricultural issues related to aflatoxin contamination
Book Synopsis The Toxicology of Aflatoxins by : David L. Eaton
Download or read book The Toxicology of Aflatoxins written by David L. Eaton and published by Elsevier. This book was released on 2013-10-22 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aflatoxins, natural fungal toxins found in foods and animal feeds, have great public health significance. This book presents the basic and applied toxicology of aflatoxins, including analytical identification, agricultural and veterinary implications, toxicology and carcinogenesis in humans, and economic and regulatory problems associated with aflatoxin contamination and control. Molecular mechanisms of aflatoxin toxicity Analytical issues in sampling and analysis Regulatory and economic issues associated with aflatoxin contamination of food and feed Presentation of human and animal toxicology, veterinary, and agricultural issues related to aflatoxin contamination
