Animal Models for Medications Screening to Treat Addiction

Animal Models for Medications Screening to Treat Addiction

Author: Richard L Bell

Publisher: Academic Press

Published: 2016-04-04

Total Pages: 564

ISBN-13: 0128040580

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Animal Models for Medications Screening to Treat Addiction, the latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field. Brings together information on the current state of medication development for drug addiction using animal models Contains comprehensive descriptions of various models associated with many forms of drug addiction Adds new information for translational research in the field of drug addiction


Book Synopsis Animal Models for Medications Screening to Treat Addiction by : Richard L Bell

Download or read book Animal Models for Medications Screening to Treat Addiction written by Richard L Bell and published by Academic Press. This book was released on 2016-04-04 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Models for Medications Screening to Treat Addiction, the latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field. Brings together information on the current state of medication development for drug addiction using animal models Contains comprehensive descriptions of various models associated with many forms of drug addiction Adds new information for translational research in the field of drug addiction

Animal Models of Drug Addiction

Animal Models of Drug Addiction

Author: Mary C. Olmstead

Publisher: Humana Press

Published: 2010-12-10

Total Pages: 484

ISBN-13: 9781607619338

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Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.


Book Synopsis Animal Models of Drug Addiction by : Mary C. Olmstead

Download or read book Animal Models of Drug Addiction written by Mary C. Olmstead and published by Humana Press. This book was released on 2010-12-10 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.

Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease

Author: Catherine M. Davis

Publisher: Elsevier Inc. Chapters

Published: 2013-05-29

Total Pages: 68

ISBN-13: 0128072180

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Preclinical animal research has contributed greatly to our understanding of numerous human disease states and will continue to provide a method for investigating the various biochemical events, physiological processes, and behavioral implications of various diseases. For substance abuse and dependence, this research has enabled scientists to gain a greater understanding of the neurochemical events involved in the brain's response to drugs, both licit and illicit, and to provide a means by which to design and test novel pharmaco-therapeutic interventions. To enable these discoveries, scientists have developed numerous animal models that attempt to replicate human drug addiction. The current review explores two popular Pavlovian conditioning procedures, conditioned place preference and conditioned taste aversion, which are used to investigate the rewarding and aversive effects (respectively) of drugs of abuse. For each procedure, a brief history of the field is followed by the advantages of the procedures and a step-by-step explanation of each procedure's conditioning protocol.


Book Synopsis Animal Models for the Study of Human Disease by : Catherine M. Davis

Download or read book Animal Models for the Study of Human Disease written by Catherine M. Davis and published by Elsevier Inc. Chapters. This book was released on 2013-05-29 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preclinical animal research has contributed greatly to our understanding of numerous human disease states and will continue to provide a method for investigating the various biochemical events, physiological processes, and behavioral implications of various diseases. For substance abuse and dependence, this research has enabled scientists to gain a greater understanding of the neurochemical events involved in the brain's response to drugs, both licit and illicit, and to provide a means by which to design and test novel pharmaco-therapeutic interventions. To enable these discoveries, scientists have developed numerous animal models that attempt to replicate human drug addiction. The current review explores two popular Pavlovian conditioning procedures, conditioned place preference and conditioned taste aversion, which are used to investigate the rewarding and aversive effects (respectively) of drugs of abuse. For each procedure, a brief history of the field is followed by the advantages of the procedures and a step-by-step explanation of each procedure's conditioning protocol.

Methods of Behavior Analysis in Neuroscience

Methods of Behavior Analysis in Neuroscience

Author: Jerry J. Buccafusco

Publisher: CRC Press

Published: 2000-08-29

Total Pages: 341

ISBN-13: 1420041819

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Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic


Book Synopsis Methods of Behavior Analysis in Neuroscience by : Jerry J. Buccafusco

Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Neural Mechanisms of Addiction

Neural Mechanisms of Addiction

Author: Mary Torregrossa

Publisher: Academic Press

Published: 2018-08-24

Total Pages: 306

ISBN-13: 0128123311

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Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. Transcends multiple neural, neurochemical and behavioral domains Summarizes advances in the field of addiction research since the advent of optogenetics Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms


Book Synopsis Neural Mechanisms of Addiction by : Mary Torregrossa

Download or read book Neural Mechanisms of Addiction written by Mary Torregrossa and published by Academic Press. This book was released on 2018-08-24 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. Transcends multiple neural, neurochemical and behavioral domains Summarizes advances in the field of addiction research since the advent of optogenetics Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms

Pathways of Addiction

Pathways of Addiction

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1996-11-01

Total Pages: 330

ISBN-13: 0309055334

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Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.


Book Synopsis Pathways of Addiction by : Institute of Medicine

Download or read book Pathways of Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1996-11-01 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.

New Treatments for Addiction

New Treatments for Addiction

Author: National Research Council

Publisher: National Academies Press

Published: 2004-07-03

Total Pages: 321

ISBN-13: 0309091284

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New and improved therapies to treat and protect against drug dependence and abuse are urgently needed. In the United States alone about 50 million people regularly smoke tobacco and another 5 million are addicted to other drugs. In a given year, millions of these individuals attemptâ€"with or without medical assistanceâ€"to quit using drugs, though relapse remains the norm. Furthermore, each year several million teenagers start smoking and nearly as many take illicit drugs for the first time. Research is advancing on promising new means of treating drug addiction using immunotherapies and sustained-release (depot) medications. The aim of this research is to develop medications that can block or significantly attenuate the psychoactive effects of such drugs as cocaine, nicotine, heroin, phencyclidine, and methamphetamine for weeks or months at a time. This represents a fundamentally new therapeutic approach that shows promise for treating drug addiction problems that were difficult to treat in the past. Despite their potential benefits, however, several characteristics of these new methods pose distinct behavioral, ethical, legal, and social challenges that require careful scrutiny. Such issues can be considered unique aspects of safety and efficacy that are fundamentally related to the distinct nature and properties of these new types of medications.


Book Synopsis New Treatments for Addiction by : National Research Council

Download or read book New Treatments for Addiction written by National Research Council and published by National Academies Press. This book was released on 2004-07-03 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: New and improved therapies to treat and protect against drug dependence and abuse are urgently needed. In the United States alone about 50 million people regularly smoke tobacco and another 5 million are addicted to other drugs. In a given year, millions of these individuals attemptâ€"with or without medical assistanceâ€"to quit using drugs, though relapse remains the norm. Furthermore, each year several million teenagers start smoking and nearly as many take illicit drugs for the first time. Research is advancing on promising new means of treating drug addiction using immunotherapies and sustained-release (depot) medications. The aim of this research is to develop medications that can block or significantly attenuate the psychoactive effects of such drugs as cocaine, nicotine, heroin, phencyclidine, and methamphetamine for weeks or months at a time. This represents a fundamentally new therapeutic approach that shows promise for treating drug addiction problems that were difficult to treat in the past. Despite their potential benefits, however, several characteristics of these new methods pose distinct behavioral, ethical, legal, and social challenges that require careful scrutiny. Such issues can be considered unique aspects of safety and efficacy that are fundamentally related to the distinct nature and properties of these new types of medications.

Textbook of Addiction Treatment

Textbook of Addiction Treatment

Author: Nady el-Guebaly

Publisher: Springer Nature

Published: 2020-11-03

Total Pages: 1512

ISBN-13: 3030363910

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Addiction is increasingly being recognized as a major global public health issue, and an ever-growing number of medical specialties, psychological and social science training programs, and professional associations are including addiction as part of their training and continuing education curricula. The first edition of this book presented an overview of the spectrum of addiction-related problems across different cultures around the globe. Sharing the experience and wisdom of more than 260 leading experts in the field, and promoted by the International Society of Addiction Medicine, it compared and contrasted clinical practices in the field of addiction medicine on the basis of neurobiological similarities as well as epidemiological and socio-cultural differences. Building on the success of this inaugural edition, and taking into account the formal and informal comments received as well as an assessment of current need, this textbook presents general updated information while retaining the most requested sections of the first edition as demonstrated by the number of chapter downloads. It also provides a basic text for those preparing for the ISAM annual certification exam. Written by some 220 international experts, it is a valuable reference resource for anyone interested in medicine, psychology, nursing, and social science.


Book Synopsis Textbook of Addiction Treatment by : Nady el-Guebaly

Download or read book Textbook of Addiction Treatment written by Nady el-Guebaly and published by Springer Nature. This book was released on 2020-11-03 with total page 1512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addiction is increasingly being recognized as a major global public health issue, and an ever-growing number of medical specialties, psychological and social science training programs, and professional associations are including addiction as part of their training and continuing education curricula. The first edition of this book presented an overview of the spectrum of addiction-related problems across different cultures around the globe. Sharing the experience and wisdom of more than 260 leading experts in the field, and promoted by the International Society of Addiction Medicine, it compared and contrasted clinical practices in the field of addiction medicine on the basis of neurobiological similarities as well as epidemiological and socio-cultural differences. Building on the success of this inaugural edition, and taking into account the formal and informal comments received as well as an assessment of current need, this textbook presents general updated information while retaining the most requested sections of the first edition as demonstrated by the number of chapter downloads. It also provides a basic text for those preparing for the ISAM annual certification exam. Written by some 220 international experts, it is a valuable reference resource for anyone interested in medicine, psychology, nursing, and social science.

Imaging the Addicted Brain

Imaging the Addicted Brain

Author:

Publisher: Academic Press

Published: 2016-08-05

Total Pages: 250

ISBN-13: 0128039396

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Imaging the Addicted Brain, the latest volume in the International Review of Neurobiology series will appeal to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume focusses on the imaging of the brain addicted to food, gambling, tobacco, and opiates. Offers a unique perspective on how addiction affects the brain Covers a broad scope of addictions, including food, gambling, tobacco, and common psychogenic agents with a focus on their effects on the brain Focuses on the use of medical imaging methods, especially MRI, to explore and explain addiction in the brain


Book Synopsis Imaging the Addicted Brain by :

Download or read book Imaging the Addicted Brain written by and published by Academic Press. This book was released on 2016-08-05 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging the Addicted Brain, the latest volume in the International Review of Neurobiology series will appeal to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume focusses on the imaging of the brain addicted to food, gambling, tobacco, and opiates. Offers a unique perspective on how addiction affects the brain Covers a broad scope of addictions, including food, gambling, tobacco, and common psychogenic agents with a focus on their effects on the brain Focuses on the use of medical imaging methods, especially MRI, to explore and explain addiction in the brain

The Development of Medications for the Treatment of Opiate and Cocaine Addictions

The Development of Medications for the Treatment of Opiate and Cocaine Addictions

Author: Committee to Study Medication Development and Research at the National Institute on Drug Abuse

Publisher: National Academies Press

Published: 1995-02-03

Total Pages: 271

ISBN-13: 0309587913

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Pharmacotherapy, as a means of treating drug addiction in combination with other treatment modalities, has received too little attention from the research community, the pharmaceutical industry, public health officials, and the federal government. Medications to combat drug addiction could have an enormous impact on the medical consequences and socioeconomic problems associated with drug abuse, both for drug-dependent individuals and for American society as a whole. This book examines the current environment for and obstacles to the development of anti-addiction medications, specifically those for treating opiate and cocaine addictions, and proposes incentives for the pharmaceutical industry that would help overcome those obstacles and accelerate the development of anti-addiction medications.


Book Synopsis The Development of Medications for the Treatment of Opiate and Cocaine Addictions by : Committee to Study Medication Development and Research at the National Institute on Drug Abuse

Download or read book The Development of Medications for the Treatment of Opiate and Cocaine Addictions written by Committee to Study Medication Development and Research at the National Institute on Drug Abuse and published by National Academies Press. This book was released on 1995-02-03 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacotherapy, as a means of treating drug addiction in combination with other treatment modalities, has received too little attention from the research community, the pharmaceutical industry, public health officials, and the federal government. Medications to combat drug addiction could have an enormous impact on the medical consequences and socioeconomic problems associated with drug abuse, both for drug-dependent individuals and for American society as a whole. This book examines the current environment for and obstacles to the development of anti-addiction medications, specifically those for treating opiate and cocaine addictions, and proposes incentives for the pharmaceutical industry that would help overcome those obstacles and accelerate the development of anti-addiction medications.