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Antimicrobials in Pharmaceutical and Medicinal Research

Author: Arti Gupta

Publisher: CRC Press

Published: 2023-04-03

Total Pages: 378

ISBN-13: 1000845559

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The need for state-of-the-art antimicrobial agents is greater than ever because of the development of multidrug resistance in communal pathogens, the rapid rise of new infections, and the potential for use of multidrug-resistant agents in biological protection. Although the need for novel antimicrobials is increasing, the development of such agents faces significant obstacles. Pharmaceutical research and development costs are estimated to be $400–$800 million per approved agent. The most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites. With collected contributions from international subject experts, this volume focuses primarily on antimicrobials. This book deliberates recent developments in microbial science in combating infectious diseases and explores advances in antimicrobial constituents and their applications in the fight against bacteria. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. The novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. We describe the concerted efforts undertaken by global communities to combat antimicrobial resistance in detail. The most efficient strategy could be a behavioural change towards indiscriminate consumption, usage, and prescription of antibiotics. Students, research scientists, academicians and policy makers can benefit from Antimicrobials in Pharmaceutical and Medicinal Research as a resource that addresses biotechnology, applied microbiology, healthcare/pharmaceutical products, medicinal plant products, and all disciplines related to antimicrobial research. Features of the book: Covers development in plant-based antimicrobials for sepsis management and progress Describes modern approaches for phyto-nanoconjugates in combating multidrug resistance in biomedicine Details methods to improve antimicrobial properties to have a longer service life in combating infection Describe bacteriocins and plant metabolites as biotechnological tools in food, pharmaceuticals and therapeutics applications Highlights natural antimicrobial therapeutic peptides Offers current and future applications of emerging antimicrobial technologies

Book Synopsis Antimicrobials in Pharmaceutical and Medicinal Research by : Arti Gupta

Download or read book Antimicrobials in Pharmaceutical and Medicinal Research written by Arti Gupta and published by CRC Press. This book was released on 2023-04-03 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for state-of-the-art antimicrobial agents is greater than ever because of the development of multidrug resistance in communal pathogens, the rapid rise of new infections, and the potential for use of multidrug-resistant agents in biological protection. Although the need for novel antimicrobials is increasing, the development of such agents faces significant obstacles. Pharmaceutical research and development costs are estimated to be $400–$800 million per approved agent. The most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites. With collected contributions from international subject experts, this volume focuses primarily on antimicrobials. This book deliberates recent developments in microbial science in combating infectious diseases and explores advances in antimicrobial constituents and their applications in the fight against bacteria. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. The novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. We describe the concerted efforts undertaken by global communities to combat antimicrobial resistance in detail. The most efficient strategy could be a behavioural change towards indiscriminate consumption, usage, and prescription of antibiotics. Students, research scientists, academicians and policy makers can benefit from Antimicrobials in Pharmaceutical and Medicinal Research as a resource that addresses biotechnology, applied microbiology, healthcare/pharmaceutical products, medicinal plant products, and all disciplines related to antimicrobial research. Features of the book: Covers development in plant-based antimicrobials for sepsis management and progress Describes modern approaches for phyto-nanoconjugates in combating multidrug resistance in biomedicine Details methods to improve antimicrobial properties to have a longer service life in combating infection Describe bacteriocins and plant metabolites as biotechnological tools in food, pharmaceuticals and therapeutics applications Highlights natural antimicrobial therapeutic peptides Offers current and future applications of emerging antimicrobial technologies

Medicinal Chemistry of Neglected and Tropical Diseases

Author: Venkatesan Jayaprakash

Publisher: CRC Press

Published: 2019-08-15

Total Pages: 374

ISBN-13: 1351011642

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Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.

Book Synopsis Medicinal Chemistry of Neglected and Tropical Diseases by : Venkatesan Jayaprakash

Download or read book Medicinal Chemistry of Neglected and Tropical Diseases written by Venkatesan Jayaprakash and published by CRC Press. This book was released on 2019-08-15 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.

Promising Antimicrobials from Natural Products

Author: Mahendra Rai

Publisher: Springer Nature

Published: 2022-02-03

Total Pages: 454

ISBN-13: 3030835049

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Given novel infectious diseases such as COVID-19 and antibiotic resistance new antimicrobial discovery is an important research area. Considering that nature is a vast source of bioactive molecules with antimicrobial activity, the main aim of this book is to present a comprehensive outlook of current research in the field of natural antimicrobials. It discusses the antimicrobial activity of medicinal plants, beehives, and mushrooms with a global coverage of antimicrobial agents from rich forests of Brazil (Amazon), North-Eastern forests of Peru, Argentina, Colombia, India, Bangladesh, Nepal, Middle East, Turkey, Croatia, Greece, Germany and Russia. The book covers the results of the in vitro screening of antimicrobial activities of extracts and isolated compounds from natural origins. It is divided into three sections: i) Section I, includes natural antimicrobials from plants; ii) Section II incorporates antimicrobial agents/secondary metabolites from plants, and (iii) Section III focuses on antimicrobials from mushrooms, beehive and delivery systems for different types of antimicrobials. Promising Antimicrobials From Natural Products is immensely useful for post graduate students, researchers in plant science, microbiology, biotechnology, pharmacology, pharma companies and those who are interested in herbal, eco-friendly, cost-effective and sustainable antimicrobials

Book Synopsis Promising Antimicrobials from Natural Products by : Mahendra Rai

Download or read book Promising Antimicrobials from Natural Products written by Mahendra Rai and published by Springer Nature. This book was released on 2022-02-03 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given novel infectious diseases such as COVID-19 and antibiotic resistance new antimicrobial discovery is an important research area. Considering that nature is a vast source of bioactive molecules with antimicrobial activity, the main aim of this book is to present a comprehensive outlook of current research in the field of natural antimicrobials. It discusses the antimicrobial activity of medicinal plants, beehives, and mushrooms with a global coverage of antimicrobial agents from rich forests of Brazil (Amazon), North-Eastern forests of Peru, Argentina, Colombia, India, Bangladesh, Nepal, Middle East, Turkey, Croatia, Greece, Germany and Russia. The book covers the results of the in vitro screening of antimicrobial activities of extracts and isolated compounds from natural origins. It is divided into three sections: i) Section I, includes natural antimicrobials from plants; ii) Section II incorporates antimicrobial agents/secondary metabolites from plants, and (iii) Section III focuses on antimicrobials from mushrooms, beehive and delivery systems for different types of antimicrobials. Promising Antimicrobials From Natural Products is immensely useful for post graduate students, researchers in plant science, microbiology, biotechnology, pharmacology, pharma companies and those who are interested in herbal, eco-friendly, cost-effective and sustainable antimicrobials

Antimicrobial Drug Discovery

Author: G. Tegos

Publisher: CABI

Published: 2012

Total Pages: 369

ISBN-13: 9781780640310

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Drug resistance is increasing among a variety of human pathogenic microorganisms such as Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumaniii, Pseudomonas aeruginosa and Enterobacter spp. (currently dubbed the 'ESKAPE' pathogens), and has emerged as one of the most important clinical challenges of this century. Increased general awareness and fear of these pathogens means there is a growing demand for research to tackle the threat of multidrug resistance. Documenting the latest research in the field, this book discusses current and promising activities to discover new antimicrobials in five key areas: molecular genetics and systems microbiology; synthetic, computational chemistry and chemoinformatics; High Throughput Screening (HTS); non-vertebrate model hosts; and light- and nano-based technologies.

Book Synopsis Antimicrobial Drug Discovery by : G. Tegos

Download or read book Antimicrobial Drug Discovery written by G. Tegos and published by CABI. This book was released on 2012 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug resistance is increasing among a variety of human pathogenic microorganisms such as Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumaniii, Pseudomonas aeruginosa and Enterobacter spp. (currently dubbed the 'ESKAPE' pathogens), and has emerged as one of the most important clinical challenges of this century. Increased general awareness and fear of these pathogens means there is a growing demand for research to tackle the threat of multidrug resistance. Documenting the latest research in the field, this book discusses current and promising activities to discover new antimicrobials in five key areas: molecular genetics and systems microbiology; synthetic, computational chemistry and chemoinformatics; High Throughput Screening (HTS); non-vertebrate model hosts; and light- and nano-based technologies.

Biochemistry and Molecular Biology of Antimicrobial Drug Action

Author: T. J. Franklin

Publisher: Springer Science & Business Media

Published: 2013-11-21

Total Pages: 173

ISBN-13: 1475745990

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The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Book Synopsis Biochemistry and Molecular Biology of Antimicrobial Drug Action by : T. J. Franklin

Download or read book Biochemistry and Molecular Biology of Antimicrobial Drug Action written by T. J. Franklin and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Antibacterial Drug Discovery to Combat MDR

Author: Iqbal Ahmad

Publisher: Springer Nature

Published: 2019-11-09

Total Pages: 680

ISBN-13: 9811398712

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This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.

Book Synopsis Antibacterial Drug Discovery to Combat MDR by : Iqbal Ahmad

Download or read book Antibacterial Drug Discovery to Combat MDR written by Iqbal Ahmad and published by Springer Nature. This book was released on 2019-11-09 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.

Antimicrobial Agents

Author: Varaprasad Bobbarala

Publisher: BoD – Books on Demand

Published: 2012-09-12

Total Pages: 436

ISBN-13: 9535107232

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This book contains precisely referenced chapters, emphasizing antibacterial agents with clinical practicality and alternatives to synthetic antibacterial agents through detailed reviews of diseases and their control using alternative approaches. The book aims at explaining bacterial diseases and their control via synthetic drugs replaced by chemicals obtained from different natural resources which present a future direction in the pharmaceutical industry. The book attempts to present emerging low cost and environmentally friendly drugs that are free from side effects studied in the overlapping disciplines of medicinal chemistry, biochemistry, microbiology and pharmacology.

Book Synopsis Antimicrobial Agents by : Varaprasad Bobbarala

Download or read book Antimicrobial Agents written by Varaprasad Bobbarala and published by BoD – Books on Demand. This book was released on 2012-09-12 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains precisely referenced chapters, emphasizing antibacterial agents with clinical practicality and alternatives to synthetic antibacterial agents through detailed reviews of diseases and their control using alternative approaches. The book aims at explaining bacterial diseases and their control via synthetic drugs replaced by chemicals obtained from different natural resources which present a future direction in the pharmaceutical industry. The book attempts to present emerging low cost and environmentally friendly drugs that are free from side effects studied in the overlapping disciplines of medicinal chemistry, biochemistry, microbiology and pharmacology.

Novel Antimicrobial Agents and Strategies

Author: David A. Phoenix

Publisher: John Wiley & Sons

Published: 2014-08-25

Total Pages: 522

ISBN-13: 3527676155

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By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broad spectrum of current and potential antimicrobial medications and treatments. The result is a comprehensive survey ranging from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, from metallic nanoparticles to photo- and sonosensitizers and to phage therapy. In each case, the therapeutic approaches are compared in terms of their mechanisms, likelihood to induce resistance, and their efficiency in a global healthcare context. Unrivaled knowledge for professionals in fundamental research, pharmaceutical development and clinical practice.

Book Synopsis Novel Antimicrobial Agents and Strategies by : David A. Phoenix

Download or read book Novel Antimicrobial Agents and Strategies written by David A. Phoenix and published by John Wiley & Sons. This book was released on 2014-08-25 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broad spectrum of current and potential antimicrobial medications and treatments. The result is a comprehensive survey ranging from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, from metallic nanoparticles to photo- and sonosensitizers and to phage therapy. In each case, the therapeutic approaches are compared in terms of their mechanisms, likelihood to induce resistance, and their efficiency in a global healthcare context. Unrivaled knowledge for professionals in fundamental research, pharmaceutical development and clinical practice.

Contemporary Approaches to Mitigating Antibacterial Drug Resistance

Author: Grewal, Ajmer Singh

Publisher: IGI Global

Published: 2024-04-01

Total Pages: 384

ISBN-13:

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In infectious disease management, antibacterial agents have long been viewed as pivotal tools in the relentless battle against microorganisms. However, the escalating threat of antibacterial drug resistance has emerged as a formidable challenge to global health. Contemporary Approaches to Mitigating Antibacterial Drug Resistance delves into the heart of this critical issue, exploring the mechanisms, consequences, and innovative strategies to counteract the surge of resistance, a phenomenon becoming increasingly pervasive and threatening worldwide. Antibacterial drug resistance, a pressing public health concern, transcends geographical boundaries. In regions where antibiotic accessibility and overuse prevail, resistance rates soar, giving rise to the ominous "superbugs." This book unravels the intricacies of drug resistance, examining its impact on infectious disease management, healthcare economics, and societal well-being. The exploration begins with a foundational understanding of antibacterial drug resistance, navigating through the intricate mechanisms that drive its rapid proliferation. Environmental and genetic factors, often overlooked, are dissected for their roles in fostering resistance. The book explores the interplay of antibacterial drugs with micro-biodiversity, shedding light on the indirect repercussions on human and environmental ecosystems. The primary audience, encompassing undergraduate and postgraduate students, medical practitioners, academicians, and researchers, will find in-depth insights into emerging therapeutic targets and recent advances in drug development. The secondary audience, including authorities in antibacterial drug resistance and institutional libraries, will discover a valuable resource addressing the multifaceted dimensions of this global menace.

Book Synopsis Contemporary Approaches to Mitigating Antibacterial Drug Resistance by : Grewal, Ajmer Singh

Download or read book Contemporary Approaches to Mitigating Antibacterial Drug Resistance written by Grewal, Ajmer Singh and published by IGI Global. This book was released on 2024-04-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: In infectious disease management, antibacterial agents have long been viewed as pivotal tools in the relentless battle against microorganisms. However, the escalating threat of antibacterial drug resistance has emerged as a formidable challenge to global health. Contemporary Approaches to Mitigating Antibacterial Drug Resistance delves into the heart of this critical issue, exploring the mechanisms, consequences, and innovative strategies to counteract the surge of resistance, a phenomenon becoming increasingly pervasive and threatening worldwide. Antibacterial drug resistance, a pressing public health concern, transcends geographical boundaries. In regions where antibiotic accessibility and overuse prevail, resistance rates soar, giving rise to the ominous "superbugs." This book unravels the intricacies of drug resistance, examining its impact on infectious disease management, healthcare economics, and societal well-being. The exploration begins with a foundational understanding of antibacterial drug resistance, navigating through the intricate mechanisms that drive its rapid proliferation. Environmental and genetic factors, often overlooked, are dissected for their roles in fostering resistance. The book explores the interplay of antibacterial drugs with micro-biodiversity, shedding light on the indirect repercussions on human and environmental ecosystems. The primary audience, encompassing undergraduate and postgraduate students, medical practitioners, academicians, and researchers, will find in-depth insights into emerging therapeutic targets and recent advances in drug development. The secondary audience, including authorities in antibacterial drug resistance and institutional libraries, will discover a valuable resource addressing the multifaceted dimensions of this global menace.

Biochemistry and Molecular Biology of Antimicrobial Drug Action

Author: Trevor J. Franklin

Publisher: Springer Science & Business Media

Published: 2005-03-03

Total Pages: 188

ISBN-13: 0387225544

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The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Book Synopsis Biochemistry and Molecular Biology of Antimicrobial Drug Action by : Trevor J. Franklin

Download or read book Biochemistry and Molecular Biology of Antimicrobial Drug Action written by Trevor J. Franklin and published by Springer Science & Business Media. This book was released on 2005-03-03 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.