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Antioxidants and Cardiovascular Disease

Author: R Nath

Publisher: ALPHA SCIENCE INTERNATIONAL LIMITED

Published: 2004-01-01

Total Pages: 325

ISBN-13: 8184872879

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This unique book authored by leading investigators in the field of Cardiovascular research and practicing clinicians across the globe details the scientific evidence for the heath effect of vitamins, antioxidants, trace elements and functional food, specifically their role in Cardiovascular system and provides up-to-date recommendations in the area of Cardiovascular nutrition including dietary micronutrients and supplements.Genetics of coronary disease as well as racial differences and risk factors, the role of Homocystine dietary fats, importance of antioxidant trace elements, genetic and racial differences especially in relation to cardiovascular effects, Clinical relevance of trace elements and minerals such as Chromium, Copper, Fluoride, Iron, Iodine, Molybdenum, Manganese, Selenium, Zinc, Calcium, Magnesium and Phosphorous have all been covered in relation to cardiovascular disease.

Book Synopsis Antioxidants and Cardiovascular Disease by : R Nath

Download or read book Antioxidants and Cardiovascular Disease written by R Nath and published by ALPHA SCIENCE INTERNATIONAL LIMITED. This book was released on 2004-01-01 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book authored by leading investigators in the field of Cardiovascular research and practicing clinicians across the globe details the scientific evidence for the heath effect of vitamins, antioxidants, trace elements and functional food, specifically their role in Cardiovascular system and provides up-to-date recommendations in the area of Cardiovascular nutrition including dietary micronutrients and supplements.Genetics of coronary disease as well as racial differences and risk factors, the role of Homocystine dietary fats, importance of antioxidant trace elements, genetic and racial differences especially in relation to cardiovascular effects, Clinical relevance of trace elements and minerals such as Chromium, Copper, Fluoride, Iron, Iodine, Molybdenum, Manganese, Selenium, Zinc, Calcium, Magnesium and Phosphorous have all been covered in relation to cardiovascular disease.

Oxidative Stress in Heart Diseases

Author: Sajal Chakraborti

Publisher: Springer Nature

Published: 2019-11-06

Total Pages: 596

ISBN-13: 9811382735

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This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

Book Synopsis Oxidative Stress in Heart Diseases by : Sajal Chakraborti

Download or read book Oxidative Stress in Heart Diseases written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

Antioxidants and Stem Cells for Coronary Heart Disease

Author: Philip B Oliva

Publisher: World Scientific

Published: 2014-01-22

Total Pages: 632

ISBN-13: 9814602345

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This book covers two known controversial topics — antioxidants and stem cells as therapies to treat coronary heart disease. Aiming to provide college-educated but not scientifically trained readership with a wealth of information about these two cutting-edge technologies, Antioxidants and Stem Cells for Coronary Heart Disease is written with minimum scientific terminology. Basic science studies and clinical trials regarding stem cells and antioxidants are discussed and peppered with anecdotes to make them understandable and entertaining to the laymen. Contents:Part I:The French ParadoxLDL Oxidation — BrieflyAcetylation of LDLFree RadicalsThe Oxygen ParadoxRetrolental Fibroplasia from 1956 to 1972: The Quiet TimeThe Second Epidemic of Retrolental Fibroplasia: 1972–20??Cytokines and ChemokinesLDL Oxidation by Free Radicals — In DetailTwo Other Ways to Oxidize LDL: Lipoxygenase and Nitric OxideWhat is the Raison d'être for Oxidized LDL?Fatty Streaks and Foam CellsEmbryonic Stem CellsAdult Stem CellsTransgenic MicePart II:Treatment of Coronary Heart Disease with Antioxidants: An IntroductionThe Mediterranean DietAcute Myocardial Infarctions in Japan and Norway from 1910 to 1950Wine, Beer, and Spirits as AntioxidantsA Perspective on Antioxidant Vitamins for the Treatment of Coronary Heart DiseaseVitamin AThe Thalidomide SagaVitamin CVitamin EDo Combinations of Antioxidant Vitamins Work Better than Individual Vitamins in Patients with Coronary Heart Disease?A RequiemMolecular Markers, Reporter Genes and Suicide GenesStem Cells for the Heart: Hype or Hope?The PrizefightBrainbowCre/Lox: A Cut-and-Paste Method of Gene Swapping Without a Mac or PC and a New Scientific Term with Vast SignificanceBacteriophage, Transgenic Mice and Transgenic MarmosetsPhage Geometry and Soccer BallsEuler's FormulaE = mc2 and Einstein's BrainThe Manhattan Project and Its Connection with Albert EinsteinA Gadget, a Little Boy and a Fat ManCamillo Golgi and Santiago Ramón Y Cajal: Bitter Rivals to The End Readership: College-educated general public and non-scientists who are interested in the topic of antioxidants and stem cells. Key Features:The book is written in plain English and scientific jargons are explained in laymen terms“Hot topics” such as embryonic stem cells, adult stem cells and antioxidants are discussedA well-researched and colourfully illustrated book for readers of the general publicKeywords:Stem Cells;Antioxidants;Coronary Heart Disease

Book Synopsis Antioxidants and Stem Cells for Coronary Heart Disease by : Philip B Oliva

Download or read book Antioxidants and Stem Cells for Coronary Heart Disease written by Philip B Oliva and published by World Scientific. This book was released on 2014-01-22 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers two known controversial topics — antioxidants and stem cells as therapies to treat coronary heart disease. Aiming to provide college-educated but not scientifically trained readership with a wealth of information about these two cutting-edge technologies, Antioxidants and Stem Cells for Coronary Heart Disease is written with minimum scientific terminology. Basic science studies and clinical trials regarding stem cells and antioxidants are discussed and peppered with anecdotes to make them understandable and entertaining to the laymen. Contents:Part I:The French ParadoxLDL Oxidation — BrieflyAcetylation of LDLFree RadicalsThe Oxygen ParadoxRetrolental Fibroplasia from 1956 to 1972: The Quiet TimeThe Second Epidemic of Retrolental Fibroplasia: 1972–20??Cytokines and ChemokinesLDL Oxidation by Free Radicals — In DetailTwo Other Ways to Oxidize LDL: Lipoxygenase and Nitric OxideWhat is the Raison d'être for Oxidized LDL?Fatty Streaks and Foam CellsEmbryonic Stem CellsAdult Stem CellsTransgenic MicePart II:Treatment of Coronary Heart Disease with Antioxidants: An IntroductionThe Mediterranean DietAcute Myocardial Infarctions in Japan and Norway from 1910 to 1950Wine, Beer, and Spirits as AntioxidantsA Perspective on Antioxidant Vitamins for the Treatment of Coronary Heart DiseaseVitamin AThe Thalidomide SagaVitamin CVitamin EDo Combinations of Antioxidant Vitamins Work Better than Individual Vitamins in Patients with Coronary Heart Disease?A RequiemMolecular Markers, Reporter Genes and Suicide GenesStem Cells for the Heart: Hype or Hope?The PrizefightBrainbowCre/Lox: A Cut-and-Paste Method of Gene Swapping Without a Mac or PC and a New Scientific Term with Vast SignificanceBacteriophage, Transgenic Mice and Transgenic MarmosetsPhage Geometry and Soccer BallsEuler's FormulaE = mc2 and Einstein's BrainThe Manhattan Project and Its Connection with Albert EinsteinA Gadget, a Little Boy and a Fat ManCamillo Golgi and Santiago Ramón Y Cajal: Bitter Rivals to The End Readership: College-educated general public and non-scientists who are interested in the topic of antioxidants and stem cells. Key Features:The book is written in plain English and scientific jargons are explained in laymen terms“Hot topics” such as embryonic stem cells, adult stem cells and antioxidants are discussedA well-researched and colourfully illustrated book for readers of the general publicKeywords:Stem Cells;Antioxidants;Coronary Heart Disease

Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention

Author: J T Kumpulainen

Publisher: Elsevier

Published: 1996-01-01

Total Pages: 462

ISBN-13: 0857093053

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Natural antioxidants and food quality in atherosclerosis and cancer prevention provides a comprehensive and up-to-date overview of the role of natural antioxidants and lipid peroxidation in atherosclerosis and cancer. The book presents important information on the presence of various flavonoids found in berries, vegetables and fruits and their antioxidative potencies, as well as the role of antioxidative vitamins and carotenoids in cardiovascular diseases and cancer. In addition, the measurement of oxidative stress in humans is surveyed.

Book Synopsis Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention by : J T Kumpulainen

Download or read book Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention written by J T Kumpulainen and published by Elsevier. This book was released on 1996-01-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural antioxidants and food quality in atherosclerosis and cancer prevention provides a comprehensive and up-to-date overview of the role of natural antioxidants and lipid peroxidation in atherosclerosis and cancer. The book presents important information on the presence of various flavonoids found in berries, vegetables and fruits and their antioxidative potencies, as well as the role of antioxidative vitamins and carotenoids in cardiovascular diseases and cancer. In addition, the measurement of oxidative stress in humans is surveyed.

Modulation of Oxidative Stress in Heart Disease

Author: Sajal Chakraborti

Publisher: Springer Nature

Published: 2019-11-10

Total Pages: 686

ISBN-13: 9811389462

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This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.

Book Synopsis Modulation of Oxidative Stress in Heart Disease by : Sajal Chakraborti

Download or read book Modulation of Oxidative Stress in Heart Disease written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-10 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.

Oxidative Stress and Vascular Disease

Author: John F. Keaney Jr.

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 404

ISBN-13: 1461546494

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One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.

Book Synopsis Oxidative Stress and Vascular Disease by : John F. Keaney Jr.

Download or read book Oxidative Stress and Vascular Disease written by John F. Keaney Jr. and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.

Antioxidants in Health and Disease

Author: Antonis Zampelas

Publisher: CRC Press

Published: 2015-06-09

Total Pages: 387

ISBN-13: 100021902X

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Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.

Book Synopsis Antioxidants in Health and Disease by : Antonis Zampelas

Download or read book Antioxidants in Health and Disease written by Antonis Zampelas and published by CRC Press. This book was released on 2015-06-09 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.

Free Radicals in Biology and Medicine

Author: Barry Halliwell

Publisher: Oxford University Press

Published: 2015

Total Pages: 961

ISBN-13: 0198717474

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Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell

Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by Oxford University Press. This book was released on 2015 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Antioxidants and Cardiovascular Disease

Author: Jean-Claude Tardif

Publisher: Springer Science & Business Media

Published: 2000

Total Pages: 320

ISBN-13: 9780792365648

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This work addresses a complex problem in cardiovascular medicine. It is written by experts in the fields of atherosclerosis, heart failure, and antioxidants. It should be of interest not only to academicians but also to practising physicians, including postdoctoral fellows, internists, cardiologists, and general practitioners. The first three chapters review the antioxidant hypothesis and its close relationship to lipid mechanisms of action and classify the different and heterogeneous pharmacological compounds with known antioxidant properties, and describe the role of dietary nutrients and supplements as well as the potential therapeutic benefit of antioxidants in coronary artery disease prevention and risk reduction, prevention of endothelial dysfunction, and prevention of chronic heart failure. Finally, current knowledge of the use of these compounds in cardiovascular medicine is summarized.

Book Synopsis Antioxidants and Cardiovascular Disease by : Jean-Claude Tardif

Download or read book Antioxidants and Cardiovascular Disease written by Jean-Claude Tardif and published by Springer Science & Business Media. This book was released on 2000 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work addresses a complex problem in cardiovascular medicine. It is written by experts in the fields of atherosclerosis, heart failure, and antioxidants. It should be of interest not only to academicians but also to practising physicians, including postdoctoral fellows, internists, cardiologists, and general practitioners. The first three chapters review the antioxidant hypothesis and its close relationship to lipid mechanisms of action and classify the different and heterogeneous pharmacological compounds with known antioxidant properties, and describe the role of dietary nutrients and supplements as well as the potential therapeutic benefit of antioxidants in coronary artery disease prevention and risk reduction, prevention of endothelial dysfunction, and prevention of chronic heart failure. Finally, current knowledge of the use of these compounds in cardiovascular medicine is summarized.

Highway to Heart Health

Author: Ross Walker

Publisher:

Published: 2000

Total Pages: 148

ISBN-13: 9780908272624

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Diet therapy to combat heart disease.

Book Synopsis Highway to Heart Health by : Ross Walker

Download or read book Highway to Heart Health written by Ross Walker and published by . This book was released on 2000 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet therapy to combat heart disease.