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Volume 2 of Formulation Science and Technology is a survey of the different types of formulations used in the chemical industry and offers numerous real-world examples of foams, gels, latexes etc. It offers in-depth explanations for research scientists, universities, and industry practitioners looking for a complete understanding of which type formulation works best for a certain application and why.
Book Synopsis Basic Principles of Formulation Types by : Tharwat F. Tadros
Download or read book Basic Principles of Formulation Types written by Tharwat F. Tadros and published by Walter de Gruyter GmbH & Co KG. This book was released on 2018-05-22 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 2 of Formulation Science and Technology is a survey of the different types of formulations used in the chemical industry and offers numerous real-world examples of foams, gels, latexes etc. It offers in-depth explanations for research scientists, universities, and industry practitioners looking for a complete understanding of which type formulation works best for a certain application and why.
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
Book Synopsis Pharmaceutical Formulation by : Geoffrey D Tovey
Download or read book Pharmaceutical Formulation written by Geoffrey D Tovey and published by Royal Society of Chemistry. This book was released on 2018-06-25 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
Volume 1 of Formulation Science and Technology is a survey of the theory of formulations in a variety of fields, as well as their rheological characterization. It offers in-depth explanations for research scientists, universities, and industry practitioners looking for a complete understanding of how different formulations behave and how to influence their performance.
Book Synopsis Basic Theory of Interfacial Phenomena and Colloid Stability by : Tharwat F. Tadros
Download or read book Basic Theory of Interfacial Phenomena and Colloid Stability written by Tharwat F. Tadros and published by Walter de Gruyter GmbH & Co KG. This book was released on 2018-05-22 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 1 of Formulation Science and Technology is a survey of the theory of formulations in a variety of fields, as well as their rheological characterization. It offers in-depth explanations for research scientists, universities, and industry practitioners looking for a complete understanding of how different formulations behave and how to influence their performance.
Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry
Book Synopsis Basic Principles of Drug Discovery and Development by : Benjamin E. Blass
Download or read book Basic Principles of Drug Discovery and Development written by Benjamin E. Blass and published by Academic Press. This book was released on 2021-03-30 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry
Surfactants... today you have probably eaten some, or rubbed others on your body. Plants, animals (including you) and microorganisms make them, and many everyday products (e.g. detergents, cosmetics, foodstuffs) contain them. Surfactant molecules have one part which is soluble in water and another which is not. This gives surfactant molecules two valuable properties: 1) they adsorb at surfaces (e.g. of an oil droplet in water), and 2) they stick together (aggregate) in water. The aggregates (micelles) are able to dissolve materials not soluble in water alone, and adsorbed surfactant layers, at the surfaces of particles or (say) oil droplets in water, stop the particles or drops sticking together. This is why stable emulsions such as milk do not separate into layers. This book treats the basic physical chemistry and physics underlying the behaviour of surfactant systems. In this book, you will first learn about some background material including hydrophobic hydration, interfacial tension and capillarity (Section I). Discussion of surfactant adsorption at liquid/fluid and solid/liquid interfaces is given in Section II, and includes thermodynamics of adsorption, dynamic and rheological aspects of liquid interfaces and the direct characterisation of surfactant monolayers. In Section III, a description is given of surfactant aggregation to give micelles, lyotropic liquid crystals, microemulsions and Winsor systems. There follows a discussion of surface forces and the way they confer stability on lyophobic colloids and thin liquid films (Section IV). Various dispersions stabilised by adsorbed surfactant or polymer (including solid in liquid dispersions, emulsions and foams) are considered in Section V. The wetting of solids and liquids is explored in Section VI. Like surfactants, small solid particles can adsorb at liquid/fluid interfaces, form monolayers and stabilise emulsions and foams. Such behaviour is covered in Section VII. It is assumed the reader has a knowledge of undergraduate physical chemistry, particularly chemical thermodynamics, and of simple physics. Mathematics (elementary algebra and calculus) is kept at a level consistent with the straightforward derivation of many of the equations presented.
Book Synopsis Surfactants by : Bob Aveyard
Download or read book Surfactants written by Bob Aveyard and published by Oxford University Press. This book was released on 2019-10-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surfactants... today you have probably eaten some, or rubbed others on your body. Plants, animals (including you) and microorganisms make them, and many everyday products (e.g. detergents, cosmetics, foodstuffs) contain them. Surfactant molecules have one part which is soluble in water and another which is not. This gives surfactant molecules two valuable properties: 1) they adsorb at surfaces (e.g. of an oil droplet in water), and 2) they stick together (aggregate) in water. The aggregates (micelles) are able to dissolve materials not soluble in water alone, and adsorbed surfactant layers, at the surfaces of particles or (say) oil droplets in water, stop the particles or drops sticking together. This is why stable emulsions such as milk do not separate into layers. This book treats the basic physical chemistry and physics underlying the behaviour of surfactant systems. In this book, you will first learn about some background material including hydrophobic hydration, interfacial tension and capillarity (Section I). Discussion of surfactant adsorption at liquid/fluid and solid/liquid interfaces is given in Section II, and includes thermodynamics of adsorption, dynamic and rheological aspects of liquid interfaces and the direct characterisation of surfactant monolayers. In Section III, a description is given of surfactant aggregation to give micelles, lyotropic liquid crystals, microemulsions and Winsor systems. There follows a discussion of surface forces and the way they confer stability on lyophobic colloids and thin liquid films (Section IV). Various dispersions stabilised by adsorbed surfactant or polymer (including solid in liquid dispersions, emulsions and foams) are considered in Section V. The wetting of solids and liquids is explored in Section VI. Like surfactants, small solid particles can adsorb at liquid/fluid interfaces, form monolayers and stabilise emulsions and foams. Such behaviour is covered in Section VII. It is assumed the reader has a knowledge of undergraduate physical chemistry, particularly chemical thermodynamics, and of simple physics. Mathematics (elementary algebra and calculus) is kept at a level consistent with the straightforward derivation of many of the equations presented.
This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book.
Book Synopsis Solubility in Pharmaceutical Chemistry by : Christoph Saal
Download or read book Solubility in Pharmaceutical Chemistry written by Christoph Saal and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-01-20 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book.
Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies
Book Synopsis Developing Solid Oral Dosage Forms by : Yihong Qiu
Download or read book Developing Solid Oral Dosage Forms written by Yihong Qiu and published by Academic Press. This book was released on 2009-03-10 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies
Sound formulation is a vital aspect of microbial products used to protect plants from pests and diseases and to improve plant performance. Formulation of Microbial Biopesticides is an in-depth treatment of this vitally important subject. Written by experts and carefully edited, this important title brings together a huge wealth of information for the first time within the covers of one book. The book is broadly divided into five sections, covering principles of formulation, organisms with peroral and contact modes of action, organisms with the power of search, and future trends. Each section contains comprehensive chapters written by internationally acknowledged experts in the areas covered; the book also includes three very useful appendices, cataloguing formulation additives, spray application criteria and terminology. This outstanding book is a vitally important reference work for anyone involved in the formulation of microbial biopesticides and should find a place on the shelves of agriculture and plant scientists, microbiologists and entomologists working in academic and commercial agrochemical situations, and in the libraries of all research establishments and companies where this exciting subject is researched, studied or taught.
Book Synopsis Formulation of Microbial Biopesticides by : H.D. Burges
Download or read book Formulation of Microbial Biopesticides written by H.D. Burges and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sound formulation is a vital aspect of microbial products used to protect plants from pests and diseases and to improve plant performance. Formulation of Microbial Biopesticides is an in-depth treatment of this vitally important subject. Written by experts and carefully edited, this important title brings together a huge wealth of information for the first time within the covers of one book. The book is broadly divided into five sections, covering principles of formulation, organisms with peroral and contact modes of action, organisms with the power of search, and future trends. Each section contains comprehensive chapters written by internationally acknowledged experts in the areas covered; the book also includes three very useful appendices, cataloguing formulation additives, spray application criteria and terminology. This outstanding book is a vitally important reference work for anyone involved in the formulation of microbial biopesticides and should find a place on the shelves of agriculture and plant scientists, microbiologists and entomologists working in academic and commercial agrochemical situations, and in the libraries of all research establishments and companies where this exciting subject is researched, studied or taught.
A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations. Unique coverage of the underlying chemistry that makes possible stable dosages Quality content written by experienced experts from the drug development industry Valuable information for academic and industrial scientists developing topical and liquid dosage formulations for pharmaceutical as well as skin care and cosmetic products
Book Synopsis Essential Chemistry for Formulators of Semisolid and Liquid Dosages by : Vitthal S. Kulkarni
Download or read book Essential Chemistry for Formulators of Semisolid and Liquid Dosages written by Vitthal S. Kulkarni and published by Academic Press. This book was released on 2015-10-15 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations. Unique coverage of the underlying chemistry that makes possible stable dosages Quality content written by experienced experts from the drug development industry Valuable information for academic and industrial scientists developing topical and liquid dosage formulations for pharmaceutical as well as skin care and cosmetic products
Book Synopsis Industrial Production and Formulation of Pesticides in Developing Countries: General principles and formulation of pesticides by : United Nations Industrial Development Organization
Download or read book Industrial Production and Formulation of Pesticides in Developing Countries: General principles and formulation of pesticides written by United Nations Industrial Development Organization and published by New York : United Nations. This book was released on 1972 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:
