Biodegradable Polymers in Pharmacy and Medicine. Classification, Chemical Structure, Principles of Biodegradation and Use

Biodegradable Polymers in Pharmacy and Medicine. Classification, Chemical Structure, Principles of Biodegradation and Use

Author: Jan Gajdziok

Publisher: GRIN Verlag

Published: 2016-09-13

Total Pages: 116

ISBN-13: 3668297754

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Document from the year 2016 in the subject Medicine - Pharmacology, Pharmacy, , course: Pharmaceutical technology, language: English, abstract: The aim of this book is to provide a brief but comprehensive overview on the issue of biodegradable polymers. The introduction chapter is followed by a description of the general characteristics of biodegradable polymers and pathways of their degradation in the human body. Particular pitfalls and specifics of their various biomedical and pharmaceutical applications, especially in the field of pharmaceutical technology, are described in order to define the ideal carrier polymer system for specific types of therapy. Finally, the work presents the classification of these polymers based on the type of degradation mechanism. This section also includes the chemical structure of particular polymer molecules, their chemical or bio-synthesis and the description of their uses in specific biomedical and pharmaceutical applications. The book could be used as a textbook for students of medical and pharmaceutical sciences as well as by researchers in this field or industrial area. In the past few decades, biodegradable polymers have reached significant importance in fields of biomedical and pharmaceutical applications. They have become preferred candidates for the manufacture of therapeutic forms, for instance, orthopaedics devices, temporary bone screws and spins, three-dimensional scaffolds for tissue engineering or drug delivery systems for sustained and targeted release. Each of these applications requires material with specific physical, biological, and chemical properties, as well as specific degradation profile. These polymers (natural or synthetic) undergo hydrolytic or enzymatic degradation, which both have some advantages and disadvantages. Most widely used polymer materials in biomedical applications are listed, including their structure and degradation pathways.


Book Synopsis Biodegradable Polymers in Pharmacy and Medicine. Classification, Chemical Structure, Principles of Biodegradation and Use by : Jan Gajdziok

Download or read book Biodegradable Polymers in Pharmacy and Medicine. Classification, Chemical Structure, Principles of Biodegradation and Use written by Jan Gajdziok and published by GRIN Verlag. This book was released on 2016-09-13 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Document from the year 2016 in the subject Medicine - Pharmacology, Pharmacy, , course: Pharmaceutical technology, language: English, abstract: The aim of this book is to provide a brief but comprehensive overview on the issue of biodegradable polymers. The introduction chapter is followed by a description of the general characteristics of biodegradable polymers and pathways of their degradation in the human body. Particular pitfalls and specifics of their various biomedical and pharmaceutical applications, especially in the field of pharmaceutical technology, are described in order to define the ideal carrier polymer system for specific types of therapy. Finally, the work presents the classification of these polymers based on the type of degradation mechanism. This section also includes the chemical structure of particular polymer molecules, their chemical or bio-synthesis and the description of their uses in specific biomedical and pharmaceutical applications. The book could be used as a textbook for students of medical and pharmaceutical sciences as well as by researchers in this field or industrial area. In the past few decades, biodegradable polymers have reached significant importance in fields of biomedical and pharmaceutical applications. They have become preferred candidates for the manufacture of therapeutic forms, for instance, orthopaedics devices, temporary bone screws and spins, three-dimensional scaffolds for tissue engineering or drug delivery systems for sustained and targeted release. Each of these applications requires material with specific physical, biological, and chemical properties, as well as specific degradation profile. These polymers (natural or synthetic) undergo hydrolytic or enzymatic degradation, which both have some advantages and disadvantages. Most widely used polymer materials in biomedical applications are listed, including their structure and degradation pathways.

Biodegradable Polymers in Clinical Use and Clinical Development

Biodegradable Polymers in Clinical Use and Clinical Development

Author: Abraham J. Domb

Publisher: John Wiley & Sons

Published: 2011-05-12

Total Pages: 594

ISBN-13: 1118015800

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This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.


Book Synopsis Biodegradable Polymers in Clinical Use and Clinical Development by : Abraham J. Domb

Download or read book Biodegradable Polymers in Clinical Use and Clinical Development written by Abraham J. Domb and published by John Wiley & Sons. This book was released on 2011-05-12 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

Handbook of Biodegradable Polymers

Handbook of Biodegradable Polymers

Author: Abraham J. Domb

Publisher: CRC Press

Published: 1998-02-04

Total Pages: 548

ISBN-13: 9781420049367

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Handbook of Biodegradable Polymers, the seventh volume in the Drug Delivery and Targeting book series, provides a source manual for synthetic procedures, properties and applications of bioerodible polymers. The authors describe widely available materials such as polyactides, collagen and gelatin, as well as polymers of emerging importance, such as the genetically-engineered and elastin-based polymers which are either proprietary or in early stages of development. Section I addresses synthetic absorbable polymers, and Section 2 profiles natural, semi-synthetic and biosynthetic polymers. Section 3 discusses the surface characterization of degradable polymers, the modeling of biodegradation and non-medical polymers. This book is ideal for researchers from academia and industry as well as chemists, pharmacists and physicians who deal with biopolymers, drug delivery and targeting, bioengineering and implantable devices.


Book Synopsis Handbook of Biodegradable Polymers by : Abraham J. Domb

Download or read book Handbook of Biodegradable Polymers written by Abraham J. Domb and published by CRC Press. This book was released on 1998-02-04 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Biodegradable Polymers, the seventh volume in the Drug Delivery and Targeting book series, provides a source manual for synthetic procedures, properties and applications of bioerodible polymers. The authors describe widely available materials such as polyactides, collagen and gelatin, as well as polymers of emerging importance, such as the genetically-engineered and elastin-based polymers which are either proprietary or in early stages of development. Section I addresses synthetic absorbable polymers, and Section 2 profiles natural, semi-synthetic and biosynthetic polymers. Section 3 discusses the surface characterization of degradable polymers, the modeling of biodegradation and non-medical polymers. This book is ideal for researchers from academia and industry as well as chemists, pharmacists and physicians who deal with biopolymers, drug delivery and targeting, bioengineering and implantable devices.

Degradable Polymers

Degradable Polymers

Author: G. Scott

Publisher: Springer Science & Business Media

Published: 2002

Total Pages: 500

ISBN-13: 9781402007903

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The emphasis in degradable polymers has changed since the first edition of this book. Biomedical and agricultural applications remain important topics of scientific and commercial interest in the second edition. However, an increased emphasis on composting as a means of recovering value from wastes has led to a new impetus to understand how plastics degrade in the environment and the implication of this for international standards. Polymers based on renewable resources are also a major topic in this edition but the debate continues about their long-term sustainability and ecological advantages over degradable man-made polymers. Degradable Polymers will be of interest not only to academic and industrial scientists working on packaging, agricultural and medical applications of plastics but also to students of environmental science and legislators concerned with the effects of man-made materials in the environment.


Book Synopsis Degradable Polymers by : G. Scott

Download or read book Degradable Polymers written by G. Scott and published by Springer Science & Business Media. This book was released on 2002 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emphasis in degradable polymers has changed since the first edition of this book. Biomedical and agricultural applications remain important topics of scientific and commercial interest in the second edition. However, an increased emphasis on composting as a means of recovering value from wastes has led to a new impetus to understand how plastics degrade in the environment and the implication of this for international standards. Polymers based on renewable resources are also a major topic in this edition but the debate continues about their long-term sustainability and ecological advantages over degradable man-made polymers. Degradable Polymers will be of interest not only to academic and industrial scientists working on packaging, agricultural and medical applications of plastics but also to students of environmental science and legislators concerned with the effects of man-made materials in the environment.

Handbook of Polymers for Pharmaceutical Technologies, Biodegradable Polymers

Handbook of Polymers for Pharmaceutical Technologies, Biodegradable Polymers

Author: Vijay Kumar Thakur

Publisher: John Wiley & Sons

Published: 2015-09-22

Total Pages: 610

ISBN-13: 1119041449

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Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers


Book Synopsis Handbook of Polymers for Pharmaceutical Technologies, Biodegradable Polymers by : Vijay Kumar Thakur

Download or read book Handbook of Polymers for Pharmaceutical Technologies, Biodegradable Polymers written by Vijay Kumar Thakur and published by John Wiley & Sons. This book was released on 2015-09-22 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers

Science and Principles of Biodegradable and Bioresorbable Medical Polymers

Science and Principles of Biodegradable and Bioresorbable Medical Polymers

Author: Xiang Cheng Zhang

Publisher: Woodhead Publishing

Published: 2016-09-22

Total Pages: 478

ISBN-13: 0081003935

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Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry


Book Synopsis Science and Principles of Biodegradable and Bioresorbable Medical Polymers by : Xiang Cheng Zhang

Download or read book Science and Principles of Biodegradable and Bioresorbable Medical Polymers written by Xiang Cheng Zhang and published by Woodhead Publishing. This book was released on 2016-09-22 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

Biodegradable polymers for industrial applications

Biodegradable polymers for industrial applications

Author: Ray Smith

Publisher: CRC Press

Published: 2005-05-17

Total Pages: 556

ISBN-13: 9780849334665

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The vast majority of plastic products are made from petroleum-based synthetic polymers that do not degrade in a landfill or in a compost-like environment. Therefore, the disposal of these products poses a serious environmental problem. An environmentally-conscious alternative is to design/synthesize polymers that are biodegradable. Biodegradable polymers for industrial applications introduces the subject in part one by outlining the classification and development of biodegradable polymers with individual chapters on polyhydroxyalkanoates, polyesteramides and thermoplastic starch biodegradable polymers and others. The second part explores the materials available for the production of biodegradable polymers. Polymers derived from sugars, natural fibres, renewable forest resources, poly(lactic acid) and protein-nanoparticle composites will be looked at in detail in this section. Part three looks at the properties and mechanisms of degradation, prefacing the subject with a chapter on current standards. The final part explores opportunities for industrial applications, with chapters on packing, agriculture and biodegradable polycaprolactone foams in supercritical carbon dioxide. Biodegradable polymers for industrial applications explores the fundamental concepts concerning the development of biodegradable polymers, degradable polymers from sustainable sources, degradation and properties and industrial applications. It is an authoritative book that will be invaluable for academics, researchers and policy makers in the industry.


Book Synopsis Biodegradable polymers for industrial applications by : Ray Smith

Download or read book Biodegradable polymers for industrial applications written by Ray Smith and published by CRC Press. This book was released on 2005-05-17 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vast majority of plastic products are made from petroleum-based synthetic polymers that do not degrade in a landfill or in a compost-like environment. Therefore, the disposal of these products poses a serious environmental problem. An environmentally-conscious alternative is to design/synthesize polymers that are biodegradable. Biodegradable polymers for industrial applications introduces the subject in part one by outlining the classification and development of biodegradable polymers with individual chapters on polyhydroxyalkanoates, polyesteramides and thermoplastic starch biodegradable polymers and others. The second part explores the materials available for the production of biodegradable polymers. Polymers derived from sugars, natural fibres, renewable forest resources, poly(lactic acid) and protein-nanoparticle composites will be looked at in detail in this section. Part three looks at the properties and mechanisms of degradation, prefacing the subject with a chapter on current standards. The final part explores opportunities for industrial applications, with chapters on packing, agriculture and biodegradable polycaprolactone foams in supercritical carbon dioxide. Biodegradable polymers for industrial applications explores the fundamental concepts concerning the development of biodegradable polymers, degradable polymers from sustainable sources, degradation and properties and industrial applications. It is an authoritative book that will be invaluable for academics, researchers and policy makers in the industry.

Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry

Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry

Author: Vijay Kumar Thakur

Publisher: John Wiley & Sons

Published: 2015-06-19

Total Pages: 530

ISBN-13: 111904135X

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Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers


Book Synopsis Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry by : Vijay Kumar Thakur

Download or read book Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry written by Vijay Kumar Thakur and published by John Wiley & Sons. This book was released on 2015-06-19 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers

Biodegradable Polymers

Biodegradable Polymers

Author: Manjari Sharma

Publisher: CRC Press

Published: 2021-04-15

Total Pages: 244

ISBN-13: 1000385183

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This book is about development of biodegradable polymers alternatives, which are required to save our reserves of fossil fuels and to save our mother earth from further environmental degradation. This book deals with the family of biodegradable polymers which have to be prepared with a novel idea of studying polymers with a “Cradle to Grave” approach. It touches upon basic materials, which can be potential materials to prepare biodegradable polymers with their basic structures, properties, behaviour and limitations known till date. This book will help students in understanding various characterization techniques which can be used for the study of identification of functional group, structural properties, thermal behaviour, crystallographic nature, mechanical properties and morphological properties through FTIR–ATR for physico chemical properties, DSC & TGA for thermal studies, XRD for crystallographic studies & SEM for morphological studies. It also provides an overview of various testing methods to analyse biodegradability including standard guideline for evaluation of biodegradation and compostability of polymer material through ASTM/ISO/EN standard methods. Note: T&F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.


Book Synopsis Biodegradable Polymers by : Manjari Sharma

Download or read book Biodegradable Polymers written by Manjari Sharma and published by CRC Press. This book was released on 2021-04-15 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about development of biodegradable polymers alternatives, which are required to save our reserves of fossil fuels and to save our mother earth from further environmental degradation. This book deals with the family of biodegradable polymers which have to be prepared with a novel idea of studying polymers with a “Cradle to Grave” approach. It touches upon basic materials, which can be potential materials to prepare biodegradable polymers with their basic structures, properties, behaviour and limitations known till date. This book will help students in understanding various characterization techniques which can be used for the study of identification of functional group, structural properties, thermal behaviour, crystallographic nature, mechanical properties and morphological properties through FTIR–ATR for physico chemical properties, DSC & TGA for thermal studies, XRD for crystallographic studies & SEM for morphological studies. It also provides an overview of various testing methods to analyse biodegradability including standard guideline for evaluation of biodegradation and compostability of polymer material through ASTM/ISO/EN standard methods. Note: T&F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices

Author: Zheng Zhang

Publisher: Elsevier Inc. Chapters

Published: 2013-12-05

Total Pages: 72

ISBN-13: 0128076755

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The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.


Book Synopsis Handbook of Polymer Applications in Medicine and Medical Devices by : Zheng Zhang

Download or read book Handbook of Polymer Applications in Medicine and Medical Devices written by Zheng Zhang and published by Elsevier Inc. Chapters. This book was released on 2013-12-05 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.