Bioinformatics for Comparative Proteomics

Bioinformatics for Comparative Proteomics

Author: Cathy H. Wu

Publisher: Humana Press

Published: 2010-11-19

Total Pages: 0

ISBN-13: 9781607619765

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With the rapid development of proteomic technologies in the life sciences and in clinical applications, many bioinformatics methodologies, databases, and software tools have been developed to support comparative proteomics study. In Bioinformatics for Comparative Proteomics, experts in the field highlight the current status, challenges, open problems, and future trends for developing bioinformatics tools and resources for comparative proteomics research in order to deliver a definitive reference providing both the breadth and depth needed on the subject. Structured in three major sections, this detailed volume covers basic bioinformatics frameworks relating to comparative proteomics, bioinformatics databases and tools for proteomics data analysis, and integrated bioinformatics systems and approaches for studying comparative proteomics in the systems biology context. Written for the highly successful Methods in Molecular BiologyTM series, the contributions in this book provide the meticulous, step-by-step description and implementation advice that is crucial for getting optimal results in the lab. Comprehensive and easy-to-use, Bioinformatics for Comparative Proteomics serves all readers who wish to learn about state-of-the-art bioinformatics databases and tools, novel computational methods and future trends in proteomics data analysis, and comparative proteomics in systems biology.


Book Synopsis Bioinformatics for Comparative Proteomics by : Cathy H. Wu

Download or read book Bioinformatics for Comparative Proteomics written by Cathy H. Wu and published by Humana Press. This book was released on 2010-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the rapid development of proteomic technologies in the life sciences and in clinical applications, many bioinformatics methodologies, databases, and software tools have been developed to support comparative proteomics study. In Bioinformatics for Comparative Proteomics, experts in the field highlight the current status, challenges, open problems, and future trends for developing bioinformatics tools and resources for comparative proteomics research in order to deliver a definitive reference providing both the breadth and depth needed on the subject. Structured in three major sections, this detailed volume covers basic bioinformatics frameworks relating to comparative proteomics, bioinformatics databases and tools for proteomics data analysis, and integrated bioinformatics systems and approaches for studying comparative proteomics in the systems biology context. Written for the highly successful Methods in Molecular BiologyTM series, the contributions in this book provide the meticulous, step-by-step description and implementation advice that is crucial for getting optimal results in the lab. Comprehensive and easy-to-use, Bioinformatics for Comparative Proteomics serves all readers who wish to learn about state-of-the-art bioinformatics databases and tools, novel computational methods and future trends in proteomics data analysis, and comparative proteomics in systems biology.

Proteome Bioinformatics

Proteome Bioinformatics

Author: Shivakumar Keerthikumar

Publisher: Methods in Molecular Biology

Published: 2018-12-29

Total Pages: 248

ISBN-13: 9781493982882

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Book Synopsis Proteome Bioinformatics by : Shivakumar Keerthikumar

Download or read book Proteome Bioinformatics written by Shivakumar Keerthikumar and published by Methods in Molecular Biology. This book was released on 2018-12-29 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioinformatics: Genomics and Proteomics

Bioinformatics: Genomics and Proteomics

Author: Ruchi Singh

Publisher: Vikas Publishing House

Published:

Total Pages:

ISBN-13: 9325978555

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This is an innovative textbook for undergraduates as well as postgraduates offering basic knowledge of biology. Its aim is to provide state-of-the-art information about this developing science that has the potential to replace existing biological approaches to study genes and proteins. The chapters are explained in a concise yet detailed manner, including ample cross-references, references to literature and databases, tables and illustrations. The book's sound approach to this intricately complex field makes it an exceptional resource for further exploration into biochemistry, molecular biology, genomics and drug designing fields. Abundant learning features make this book the ideal teaching and learning tool. KEY FEATURES • Illustrations to bolster understanding of complex biochemical relations • Tables for quick access to precise data • Extensive end-of-chapter exercises and references • The most basic details furnished for those who are new to biology • User-friendly, Internet-based bioinformatics tools that allow researchers to extract information from databases and analyze it • Analysis of one software tool discussed in each chapter step-by-step from entering the input till interpretation of the results This is an in-depth textbook written for the biologist who wants a thorough understanding of the popular bioinformatics programs and molecular databases currently in use. It provides a broad, application-oriented overview of this technology.


Book Synopsis Bioinformatics: Genomics and Proteomics by : Ruchi Singh

Download or read book Bioinformatics: Genomics and Proteomics written by Ruchi Singh and published by Vikas Publishing House. This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an innovative textbook for undergraduates as well as postgraduates offering basic knowledge of biology. Its aim is to provide state-of-the-art information about this developing science that has the potential to replace existing biological approaches to study genes and proteins. The chapters are explained in a concise yet detailed manner, including ample cross-references, references to literature and databases, tables and illustrations. The book's sound approach to this intricately complex field makes it an exceptional resource for further exploration into biochemistry, molecular biology, genomics and drug designing fields. Abundant learning features make this book the ideal teaching and learning tool. KEY FEATURES • Illustrations to bolster understanding of complex biochemical relations • Tables for quick access to precise data • Extensive end-of-chapter exercises and references • The most basic details furnished for those who are new to biology • User-friendly, Internet-based bioinformatics tools that allow researchers to extract information from databases and analyze it • Analysis of one software tool discussed in each chapter step-by-step from entering the input till interpretation of the results This is an in-depth textbook written for the biologist who wants a thorough understanding of the popular bioinformatics programs and molecular databases currently in use. It provides a broad, application-oriented overview of this technology.

Computing for Comparative Microbial Genomics

Computing for Comparative Microbial Genomics

Author: David Wayne Ussery

Publisher: Springer Science & Business Media

Published: 2009-02-26

Total Pages: 272

ISBN-13: 1848002548

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Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.


Book Synopsis Computing for Comparative Microbial Genomics by : David Wayne Ussery

Download or read book Computing for Comparative Microbial Genomics written by David Wayne Ussery and published by Springer Science & Business Media. This book was released on 2009-02-26 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.

Network-Based Proteomics

Network-Based Proteomics

Author: Wilson Wen Bin Goh

Publisher: Imperial College Press

Published: 2016-09-30

Total Pages: 300

ISBN-13: 9781783269013

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Proteomics, as the study of all expressed proteins within a given system, is a fast-growing field in which its importance in contemporary biological research remains understated. The study of network-based proteomics provides a wealth of direct information not inferable from indirect transcriptional measurements. This means that direct protein observations could yield deeper biological insight and the increased development of novel medical interventions.This timely book offers insights into the technological developments in proteomics and introduces the reader to the issues in proteomic data and their origins. For each issue, key instances of network-based techniques are described alongside their shortcomings and comparative performance-based analysis. Just as proteomic technologies are evolving, so too are the data challenges and possibilities that emerge.The authors are at the forefront of this rapidly evolving field, and thus present findings from a chronological perspective, allowing the readers to see that, as techniques become more difficult with each iteration, so too does the complexity of each new challenge. This specialized insight will interest practitioners and specialists actively working in proteomics and networks and those interested in developing translational research approaches utilizing cutting-edge informatics alongside high-throughput technologies.


Book Synopsis Network-Based Proteomics by : Wilson Wen Bin Goh

Download or read book Network-Based Proteomics written by Wilson Wen Bin Goh and published by Imperial College Press. This book was released on 2016-09-30 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomics, as the study of all expressed proteins within a given system, is a fast-growing field in which its importance in contemporary biological research remains understated. The study of network-based proteomics provides a wealth of direct information not inferable from indirect transcriptional measurements. This means that direct protein observations could yield deeper biological insight and the increased development of novel medical interventions.This timely book offers insights into the technological developments in proteomics and introduces the reader to the issues in proteomic data and their origins. For each issue, key instances of network-based techniques are described alongside their shortcomings and comparative performance-based analysis. Just as proteomic technologies are evolving, so too are the data challenges and possibilities that emerge.The authors are at the forefront of this rapidly evolving field, and thus present findings from a chronological perspective, allowing the readers to see that, as techniques become more difficult with each iteration, so too does the complexity of each new challenge. This specialized insight will interest practitioners and specialists actively working in proteomics and networks and those interested in developing translational research approaches utilizing cutting-edge informatics alongside high-throughput technologies.

Bioinformatics of Human Proteomics

Bioinformatics of Human Proteomics

Author: Xiangdong Wang

Publisher: Springer Science & Business Media

Published: 2013-01-26

Total Pages: 396

ISBN-13: 9400758111

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“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.


Book Synopsis Bioinformatics of Human Proteomics by : Xiangdong Wang

Download or read book Bioinformatics of Human Proteomics written by Xiangdong Wang and published by Springer Science & Business Media. This book was released on 2013-01-26 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.

Computation in BioInformatics

Computation in BioInformatics

Author: S. Balamurugan

Publisher: John Wiley & Sons

Published: 2021-10-19

Total Pages: 354

ISBN-13: 1119654718

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COMPUTATION IN BIOINFORMATICS Bioinformatics is a platform between the biology and information technology and this book provides readers with an understanding of the use of bioinformatics tools in new drug design. The discovery of new solutions to pandemics is facilitated through the use of promising bioinformatics techniques and integrated approaches. This book covers a broad spectrum of the bioinformatics field, starting with the basic principles, concepts, and application areas. Also covered is the role of bioinformatics in drug design and discovery, including aspects of molecular modeling. Some of the chapters provide detailed information on bioinformatics related topics, such as silicon design, protein modeling, DNA microarray analysis, DNA-RNA barcoding, and gene sequencing, all of which are currently needed in the industry. Also included are specialized topics, such as bioinformatics in cancer detection, genomics, and proteomics. Moreover, a few chapters explain highly advanced topics, like machine learning and covalent approaches to drug design and discovery, all of which are significant in pharma and biotech research and development. Audience Researchers and engineers in computation biology, information technology, bioinformatics, drug design, biotechnology, pharmaceutical sciences.


Book Synopsis Computation in BioInformatics by : S. Balamurugan

Download or read book Computation in BioInformatics written by S. Balamurugan and published by John Wiley & Sons. This book was released on 2021-10-19 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: COMPUTATION IN BIOINFORMATICS Bioinformatics is a platform between the biology and information technology and this book provides readers with an understanding of the use of bioinformatics tools in new drug design. The discovery of new solutions to pandemics is facilitated through the use of promising bioinformatics techniques and integrated approaches. This book covers a broad spectrum of the bioinformatics field, starting with the basic principles, concepts, and application areas. Also covered is the role of bioinformatics in drug design and discovery, including aspects of molecular modeling. Some of the chapters provide detailed information on bioinformatics related topics, such as silicon design, protein modeling, DNA microarray analysis, DNA-RNA barcoding, and gene sequencing, all of which are currently needed in the industry. Also included are specialized topics, such as bioinformatics in cancer detection, genomics, and proteomics. Moreover, a few chapters explain highly advanced topics, like machine learning and covalent approaches to drug design and discovery, all of which are significant in pharma and biotech research and development. Audience Researchers and engineers in computation biology, information technology, bioinformatics, drug design, biotechnology, pharmaceutical sciences.

Handbook of Comparative Genomics

Handbook of Comparative Genomics

Author: Cecilia Saccone

Publisher: John Wiley & Sons

Published: 2005-03-11

Total Pages: 442

ISBN-13: 0471326410

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This comprehensive reference covers the comparative methodologyinvolved in studying molecular evolution. Providing a practicalintroduction to the role of bioinformatics in comparative genomics,this publication further discusses the basic technology used ingenome sequencing projects and provides an overview of genomestorage databases currently in use. This timely and cutting-edge text also: Reviews the basic principles of genomics and gene expressionanalysis Discusses analytic methods in proteomics andtranscriptomics Includes a comprehensive list of Web resource


Book Synopsis Handbook of Comparative Genomics by : Cecilia Saccone

Download or read book Handbook of Comparative Genomics written by Cecilia Saccone and published by John Wiley & Sons. This book was released on 2005-03-11 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference covers the comparative methodologyinvolved in studying molecular evolution. Providing a practicalintroduction to the role of bioinformatics in comparative genomics,this publication further discusses the basic technology used ingenome sequencing projects and provides an overview of genomestorage databases currently in use. This timely and cutting-edge text also: Reviews the basic principles of genomics and gene expressionanalysis Discusses analytic methods in proteomics andtranscriptomics Includes a comprehensive list of Web resource

Comparative Genomics and Proteomics in Drug Discovery

Comparative Genomics and Proteomics in Drug Discovery

Author: John Parrington

Publisher: Taylor & Francis

Published: 2007

Total Pages: 208

ISBN-13:

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Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds.


Book Synopsis Comparative Genomics and Proteomics in Drug Discovery by : John Parrington

Download or read book Comparative Genomics and Proteomics in Drug Discovery written by John Parrington and published by Taylor & Francis. This book was released on 2007 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds.

Computational Methods for Mass Spectrometry Proteomics

Computational Methods for Mass Spectrometry Proteomics

Author: Ingvar Eidhammer

Publisher: John Wiley & Sons

Published: 2008-02-28

Total Pages: 296

ISBN-13: 9780470724293

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Proteomics is the study of the subsets of proteins present in different parts of an organism and how they change with time and varying conditions. Mass spectrometry is the leading technology used in proteomics, and the field relies heavily on bioinformatics to process and analyze the acquired data. Since recent years have seen tremendous developments in instrumentation and proteomics-related bioinformatics, there is clearly a need for a solid introduction to the crossroads where proteomics and bioinformatics meet. Computational Methods for Mass Spectrometry Proteomics describes the different instruments and methodologies used in proteomics in a unified manner. The authors put an emphasis on the computational methods for the different phases of a proteomics analysis, but the underlying principles in protein chemistry and instrument technology are also described. The book is illustrated by a number of figures and examples, and contains exercises for the reader. Written in an accessible yet rigorous style, it is a valuable reference for both informaticians and biologists. Computational Methods for Mass Spectrometry Proteomics is suited for advanced undergraduate and graduate students of bioinformatics and molecular biology with an interest in proteomics. It also provides a good introduction and reference source for researchers new to proteomics, and for people who come into more peripheral contact with the field.


Book Synopsis Computational Methods for Mass Spectrometry Proteomics by : Ingvar Eidhammer

Download or read book Computational Methods for Mass Spectrometry Proteomics written by Ingvar Eidhammer and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomics is the study of the subsets of proteins present in different parts of an organism and how they change with time and varying conditions. Mass spectrometry is the leading technology used in proteomics, and the field relies heavily on bioinformatics to process and analyze the acquired data. Since recent years have seen tremendous developments in instrumentation and proteomics-related bioinformatics, there is clearly a need for a solid introduction to the crossroads where proteomics and bioinformatics meet. Computational Methods for Mass Spectrometry Proteomics describes the different instruments and methodologies used in proteomics in a unified manner. The authors put an emphasis on the computational methods for the different phases of a proteomics analysis, but the underlying principles in protein chemistry and instrument technology are also described. The book is illustrated by a number of figures and examples, and contains exercises for the reader. Written in an accessible yet rigorous style, it is a valuable reference for both informaticians and biologists. Computational Methods for Mass Spectrometry Proteomics is suited for advanced undergraduate and graduate students of bioinformatics and molecular biology with an interest in proteomics. It also provides a good introduction and reference source for researchers new to proteomics, and for people who come into more peripheral contact with the field.