Biomedical Modeling and Simulation on a PC

Biomedical Modeling and Simulation on a PC

Author: Rogier P.van Wijk van Brievingh

Publisher: Springer Science & Business Media

Published: 2013-03-12

Total Pages: 533

ISBN-13: 1461391636

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I have long had an interest in the life sciences, but have had few opportunities to indulge that interest in my professional activities. It has only been through simulation that those opportunities have arisen. Some of my most enjoyable classes were those I taught to students in the life sciences, where I attempted to show them the value of simulation to their discipline. That there is such a value cannot be questioned. Whether you are interested in population ecology, phar macokinetics, the cardiovascular system, or cell interaction, simulation can play a vital role in explaining the underlying processes and in enhancing our understanding of these processes. This book comprises an excellent collection of contributions, and clearly demonstrates the value of simulation in the particular areas of physiology and bioengineering. My main frustration when teaching these classes to people with little or no computer background was the lack of suitable simulation software. This di rectly inspired my own attempts at producing software usable by the computer novice. It is especially nice that software is available that enables readers to experience the examples in this book for themselves. I would like to congratulate and thank the editors, Rogier P. van Wijk van Brievingh and Dietmar P. P. Moller, for all of their excellent efforts. They should be proud of their achievement. This is the sixth volume in the Advances in Simulation series, and other volumes are in preparation.


Book Synopsis Biomedical Modeling and Simulation on a PC by : Rogier P.van Wijk van Brievingh

Download or read book Biomedical Modeling and Simulation on a PC written by Rogier P.van Wijk van Brievingh and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: I have long had an interest in the life sciences, but have had few opportunities to indulge that interest in my professional activities. It has only been through simulation that those opportunities have arisen. Some of my most enjoyable classes were those I taught to students in the life sciences, where I attempted to show them the value of simulation to their discipline. That there is such a value cannot be questioned. Whether you are interested in population ecology, phar macokinetics, the cardiovascular system, or cell interaction, simulation can play a vital role in explaining the underlying processes and in enhancing our understanding of these processes. This book comprises an excellent collection of contributions, and clearly demonstrates the value of simulation in the particular areas of physiology and bioengineering. My main frustration when teaching these classes to people with little or no computer background was the lack of suitable simulation software. This di rectly inspired my own attempts at producing software usable by the computer novice. It is especially nice that software is available that enables readers to experience the examples in this book for themselves. I would like to congratulate and thank the editors, Rogier P. van Wijk van Brievingh and Dietmar P. P. Moller, for all of their excellent efforts. They should be proud of their achievement. This is the sixth volume in the Advances in Simulation series, and other volumes are in preparation.


Biomedical Modeling and Simulation on a PC

Biomedical Modeling and Simulation on a PC

Author: R. P. van Wijk van Brievingh

Publisher: Springer

Published: 1993-01-01

Total Pages: 517

ISBN-13: 9783540976509

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Book Synopsis Biomedical Modeling and Simulation on a PC by : R. P. van Wijk van Brievingh

Download or read book Biomedical Modeling and Simulation on a PC written by R. P. van Wijk van Brievingh and published by Springer. This book was released on 1993-01-01 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Biomedical Modeling and Simulation on a PC

Biomedical Modeling and Simulation on a PC

Author:

Publisher:

Published: 1993

Total Pages: 0

ISBN-13:

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Book Synopsis Biomedical Modeling and Simulation on a PC by :

Download or read book Biomedical Modeling and Simulation on a PC written by and published by . This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

Author: Willem L. van Meurs

Publisher: McGraw Hill Professional

Published: 2011-08-07

Total Pages: 216

ISBN-13: 0071714464

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THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.


Book Synopsis Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology by : Willem L. van Meurs

Download or read book Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology written by Willem L. van Meurs and published by McGraw Hill Professional. This book was released on 2011-08-07 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.


Mathematical and Computational Modeling and Simulation

Mathematical and Computational Modeling and Simulation

Author: Dietmar P.F. Möller

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 438

ISBN-13: 3642187099

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This introduction and textbook familiarizes engineers with the use of mathematical and computational modeling and simulation in a way that develops their understanding of the solution characteristics of a broad class of real-world problems. The relevant basic and advanced methodologies are explained in detail, with special emphasis on ill-defined problems. Some fifteen simulation systems are presented on the language and the logical level. Moreover, the reader also can accumulate an experiential overview by studying the wide variety of case studies spanning much of science and engineering. The latter are briefly described within the book but their full versions as well as some simulation software demos are available on the Web. The book can be used for courses on various levels as well as for self-study. Advanced sections are identified and can be skipped in a first reading or in undergraduate courses.


Book Synopsis Mathematical and Computational Modeling and Simulation by : Dietmar P.F. Möller

Download or read book Mathematical and Computational Modeling and Simulation written by Dietmar P.F. Möller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introduction and textbook familiarizes engineers with the use of mathematical and computational modeling and simulation in a way that develops their understanding of the solution characteristics of a broad class of real-world problems. The relevant basic and advanced methodologies are explained in detail, with special emphasis on ill-defined problems. Some fifteen simulation systems are presented on the language and the logical level. Moreover, the reader also can accumulate an experiential overview by studying the wide variety of case studies spanning much of science and engineering. The latter are briefly described within the book but their full versions as well as some simulation software demos are available on the Web. The book can be used for courses on various levels as well as for self-study. Advanced sections are identified and can be skipped in a first reading or in undergraduate courses.


Modeling and Simulation in the Medical and Health Sciences

Modeling and Simulation in the Medical and Health Sciences

Author: John A. Sokolowski

Publisher: John Wiley & Sons

Published: 2012-01-25

Total Pages: 270

ISBN-13: 1118003195

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This edited book is divided into three parts: Fundamentals of Medical and Health Sciences Modeling and Simulation introduces modeling and simulation in the medical and health sciences; Medical and Health Sciences Models provides the theoretical underpinnings of medical and health sciences modeling; and Modeling and Simulation Applications in Medical and Health Sciences focuses on teaching, training, and research applications. The book begins with a general discussion of modeling and simulation from the modeling and simulation discipline perspective. This discussion grounds the reader in common terminology. It also relates this terminology to concepts found in the medical and health care (MHC) area to help bridge the gap between developers and MHC practitioners. Three distinct modes of modeling and simulation are described: live, constructive, and virtual. The live approach explains the concept of using real (live) people employing real equipment for training purposes. The constructive mode is a means of engaging medical modeling and simulation. In constructive simulation, simulated people and simulated equipment are developed to augment real-world conditions for training or experimentation purposes. The virtual mode is perhaps the most fascinating as virtual operating rooms and synthetic training environments are being produced for practitioners and educators at break-neck speed. In this mode, real people are employing simulated equipment to improve physical skills and decision-making ability.


Book Synopsis Modeling and Simulation in the Medical and Health Sciences by : John A. Sokolowski

Download or read book Modeling and Simulation in the Medical and Health Sciences written by John A. Sokolowski and published by John Wiley & Sons. This book was released on 2012-01-25 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book is divided into three parts: Fundamentals of Medical and Health Sciences Modeling and Simulation introduces modeling and simulation in the medical and health sciences; Medical and Health Sciences Models provides the theoretical underpinnings of medical and health sciences modeling; and Modeling and Simulation Applications in Medical and Health Sciences focuses on teaching, training, and research applications. The book begins with a general discussion of modeling and simulation from the modeling and simulation discipline perspective. This discussion grounds the reader in common terminology. It also relates this terminology to concepts found in the medical and health care (MHC) area to help bridge the gap between developers and MHC practitioners. Three distinct modes of modeling and simulation are described: live, constructive, and virtual. The live approach explains the concept of using real (live) people employing real equipment for training purposes. The constructive mode is a means of engaging medical modeling and simulation. In constructive simulation, simulated people and simulated equipment are developed to augment real-world conditions for training or experimentation purposes. The virtual mode is perhaps the most fascinating as virtual operating rooms and synthetic training environments are being produced for practitioners and educators at break-neck speed. In this mode, real people are employing simulated equipment to improve physical skills and decision-making ability.


Computer Modeling and Simulations of Complex Biological Systems, 2nd Edition

Computer Modeling and Simulations of Complex Biological Systems, 2nd Edition

Author: S. Sitharama Iyengar

Publisher: CRC Press

Published: 1997-11-20

Total Pages: 212

ISBN-13: 9780849379628

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This unique text explores the use of innovative modeling techniques in effecting a better understanding of complex diseases such as AIDS and cancer. From a way of representing the computational properties of protein-folding problems to computer simulation of bimodal neurons and networks, Computer Modeling and Simulations of Complex Biological Systems examines several modeling methodologies and integrates them across a variety of disciplines. This interdisciplinary approach suggests new ways to solve complex problems pertaining to biological systems. Written in clear and simple terms appropriate for both the novice and the experienced researcher, the book presents a step-by-step approach to the subject and includes numerous examples that explain the concepts presented in the text.


Book Synopsis Computer Modeling and Simulations of Complex Biological Systems, 2nd Edition by : S. Sitharama Iyengar

Download or read book Computer Modeling and Simulations of Complex Biological Systems, 2nd Edition written by S. Sitharama Iyengar and published by CRC Press. This book was released on 1997-11-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique text explores the use of innovative modeling techniques in effecting a better understanding of complex diseases such as AIDS and cancer. From a way of representing the computational properties of protein-folding problems to computer simulation of bimodal neurons and networks, Computer Modeling and Simulations of Complex Biological Systems examines several modeling methodologies and integrates them across a variety of disciplines. This interdisciplinary approach suggests new ways to solve complex problems pertaining to biological systems. Written in clear and simple terms appropriate for both the novice and the experienced researcher, the book presents a step-by-step approach to the subject and includes numerous examples that explain the concepts presented in the text.


Biomedical Applications of Computer Modeling

Biomedical Applications of Computer Modeling

Author: Arthur Christopoulos

Publisher: CRC Press

Published: 2000-09-19

Total Pages: 260

ISBN-13: 1420041878

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Up to the last decade or so, most general modeling approaches to the study of molecular components of biological responses have required significant amount of computer time, expertise, and resources, as well as highly specialized and often custom-written programs. With Biomedical Applications of Computer Modeling you don't have to be a computer sci


Book Synopsis Biomedical Applications of Computer Modeling by : Arthur Christopoulos

Download or read book Biomedical Applications of Computer Modeling written by Arthur Christopoulos and published by CRC Press. This book was released on 2000-09-19 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up to the last decade or so, most general modeling approaches to the study of molecular components of biological responses have required significant amount of computer time, expertise, and resources, as well as highly specialized and often custom-written programs. With Biomedical Applications of Computer Modeling you don't have to be a computer sci


Biological Modeling and Simulation

Biological Modeling and Simulation

Author: Russell Schwartz

Publisher: MIT Press

Published: 2008-07-25

Total Pages: 403

ISBN-13: 0262195844

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A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.


Book Synopsis Biological Modeling and Simulation by : Russell Schwartz

Download or read book Biological Modeling and Simulation written by Russell Schwartz and published by MIT Press. This book was released on 2008-07-25 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.


Modeling and Computer Simulation

Modeling and Computer Simulation

Author: Dragan Cvetković

Publisher: BoD – Books on Demand

Published: 2019-04-10

Total Pages: 88

ISBN-13: 1789857953

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Computer simulation or a computer model has the task of simulating the behaviour of an abstract model of a particular system. Computer simulations have become a useful part of mathematical modeling of many natural systems in physics, quantum mechanics, chemistry, biology, economic systems, psychology, and social sciences, as well as in the engineering process of new technologies. The authors of the five chapters have presented various applications of computer simulations as well as their advantages and disadvantages. They describe the process of modeling and its simulation of heat recovery steam generators, the chronometer detent escapement mechanism, relevant sociotechnical processes with regard to new housing and building law and regional management trends in the European Union, and the agent-based model for biological systems.


Book Synopsis Modeling and Computer Simulation by : Dragan Cvetković

Download or read book Modeling and Computer Simulation written by Dragan Cvetković and published by BoD – Books on Demand. This book was released on 2019-04-10 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer simulation or a computer model has the task of simulating the behaviour of an abstract model of a particular system. Computer simulations have become a useful part of mathematical modeling of many natural systems in physics, quantum mechanics, chemistry, biology, economic systems, psychology, and social sciences, as well as in the engineering process of new technologies. The authors of the five chapters have presented various applications of computer simulations as well as their advantages and disadvantages. They describe the process of modeling and its simulation of heat recovery steam generators, the chronometer detent escapement mechanism, relevant sociotechnical processes with regard to new housing and building law and regional management trends in the European Union, and the agent-based model for biological systems.