Biomolecular Kinetics

Biomolecular Kinetics

Author: Clive R. Bagshaw

Publisher: CRC Press

Published: 2017-10-04

Total Pages: 446

ISBN-13: 1498727247

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"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.


Book Synopsis Biomolecular Kinetics by : Clive R. Bagshaw

Download or read book Biomolecular Kinetics written by Clive R. Bagshaw and published by CRC Press. This book was released on 2017-10-04 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: "a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.

Biomolecular Kinetics

Biomolecular Kinetics

Author: Clive R. Bagshaw

Publisher: CRC Press

Published: 2017-10-04

Total Pages: 883

ISBN-13: 1351646664

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"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.


Book Synopsis Biomolecular Kinetics by : Clive R. Bagshaw

Download or read book Biomolecular Kinetics written by Clive R. Bagshaw and published by CRC Press. This book was released on 2017-10-04 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: "a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.

Biomolecular Kinetics and Cellular Dynamics

Biomolecular Kinetics and Cellular Dynamics

Author: K. Dane Wittrup

Publisher: Garland Science

Published: 2008-01

Total Pages: 550

ISBN-13: 9780815341390

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Book Synopsis Biomolecular Kinetics and Cellular Dynamics by : K. Dane Wittrup

Download or read book Biomolecular Kinetics and Cellular Dynamics written by K. Dane Wittrup and published by Garland Science. This book was released on 2008-01 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Parallel Computing Methods for Probing Biomolecular Kinetics and Thermodynamics

Parallel Computing Methods for Probing Biomolecular Kinetics and Thermodynamics

Author: Guha Jayachandran

Publisher:

Published: 2007

Total Pages: 272

ISBN-13:

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Book Synopsis Parallel Computing Methods for Probing Biomolecular Kinetics and Thermodynamics by : Guha Jayachandran

Download or read book Parallel Computing Methods for Probing Biomolecular Kinetics and Thermodynamics written by Guha Jayachandran and published by . This book was released on 2007 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms, thermodynamics and kinetics of ligand binding revealed from molecular simulations and machine learning

Mechanisms, thermodynamics and kinetics of ligand binding revealed from molecular simulations and machine learning

Author: Yinglong Miao

Publisher: Frontiers Media SA

Published: 2023-02-24

Total Pages: 179

ISBN-13: 2832515126

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Book Synopsis Mechanisms, thermodynamics and kinetics of ligand binding revealed from molecular simulations and machine learning by : Yinglong Miao

Download or read book Mechanisms, thermodynamics and kinetics of ligand binding revealed from molecular simulations and machine learning written by Yinglong Miao and published by Frontiers Media SA. This book was released on 2023-02-24 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Kinetics in Condensed Phases

Molecular Kinetics in Condensed Phases

Author: Ron Elber

Publisher: John Wiley & Sons

Published: 2019-12-06

Total Pages: 268

ISBN-13: 1119176794

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A guide to the theoretical and computational toolkits for the modern study of molecular kinetics in condensed phases Molecular Kinetics in Condensed Phases: Theory, Simulation and Analysis puts the focus on the theory, algorithms, simulations methods and analysis of molecular kinetics in condensed phases. The authors – noted experts on the topic – offer a detailed and thorough description of modern theories and simulation methods to model molecular events. They highlight the rigorous stochastic modelling of molecular processes and the use of mathematical models to reproduce experimental observations, such as rate coefficients, mean first passage times and transition path times. The book’s exploration of simulations examines atomically detailed modelling of molecules in action and the connections of these simulations to theory and experiment. The authors also explore the applications that range from simple intuitive examples of one- and two-dimensional systems to complex solvated macromolecules. This important book: Offers an introduction to the topic that combines theory, simulation and analysis Presents a guide written by authors that are well-known and highly regarded leaders in their fields Contains detailed examples and explanation of how to conduct computer simulations of kinetics. A detailed study of a two-dimensional system and of a solvated peptide are discussed. Discusses modern developments in the field and explains their connection to the more traditional concepts in chemical dynamics Written for students and academic researchers in the fields of chemical kinetics, chemistry, computational statistical mechanics, biophysics and computational biology, Molecular Kinetics in Condensed Phases is the authoritative guide to the theoretical and computational toolkits for the study of molecular kinetics in condensed phases.


Book Synopsis Molecular Kinetics in Condensed Phases by : Ron Elber

Download or read book Molecular Kinetics in Condensed Phases written by Ron Elber and published by John Wiley & Sons. This book was released on 2019-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the theoretical and computational toolkits for the modern study of molecular kinetics in condensed phases Molecular Kinetics in Condensed Phases: Theory, Simulation and Analysis puts the focus on the theory, algorithms, simulations methods and analysis of molecular kinetics in condensed phases. The authors – noted experts on the topic – offer a detailed and thorough description of modern theories and simulation methods to model molecular events. They highlight the rigorous stochastic modelling of molecular processes and the use of mathematical models to reproduce experimental observations, such as rate coefficients, mean first passage times and transition path times. The book’s exploration of simulations examines atomically detailed modelling of molecules in action and the connections of these simulations to theory and experiment. The authors also explore the applications that range from simple intuitive examples of one- and two-dimensional systems to complex solvated macromolecules. This important book: Offers an introduction to the topic that combines theory, simulation and analysis Presents a guide written by authors that are well-known and highly regarded leaders in their fields Contains detailed examples and explanation of how to conduct computer simulations of kinetics. A detailed study of a two-dimensional system and of a solvated peptide are discussed. Discusses modern developments in the field and explains their connection to the more traditional concepts in chemical dynamics Written for students and academic researchers in the fields of chemical kinetics, chemistry, computational statistical mechanics, biophysics and computational biology, Molecular Kinetics in Condensed Phases is the authoritative guide to the theoretical and computational toolkits for the study of molecular kinetics in condensed phases.

Binding and Kinetics for Molecular Biologists

Binding and Kinetics for Molecular Biologists

Author: James Andrew Goodrich

Publisher: CSHL Press

Published: 2007

Total Pages: 188

ISBN-13: 0879697369

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This handbook offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable as an introduction for students. Topics covered range from the basics — such as measuring the concentrations of macromolecules — through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis.


Book Synopsis Binding and Kinetics for Molecular Biologists by : James Andrew Goodrich

Download or read book Binding and Kinetics for Molecular Biologists written by James Andrew Goodrich and published by CSHL Press. This book was released on 2007 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable as an introduction for students. Topics covered range from the basics — such as measuring the concentrations of macromolecules — through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis.

Biochemistry

Biochemistry

Author: David E. Metzler

Publisher: Academic Press

Published: 2001-03-23

Total Pages: 968

ISBN-13: 0124925405

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Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.


Book Synopsis Biochemistry by : David E. Metzler

Download or read book Biochemistry written by David E. Metzler and published by Academic Press. This book was released on 2001-03-23 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.

Molecular Modeling and Simulation: An Interdisciplinary Guide

Molecular Modeling and Simulation: An Interdisciplinary Guide

Author: Tamar Schlick

Publisher: Springer Science & Business Media

Published: 2010-08-03

Total Pages: 757

ISBN-13: 1441963510

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Very broad overview of the field intended for an interdisciplinary audience; Lively discussion of current challenges written in a colloquial style; Author is a rising star in this discipline; Suitably accessible for beginners and suitably rigorous for experts; Features extensive four-color illustrations; Appendices featuring homework assignments and reading lists complement the material in the main text


Book Synopsis Molecular Modeling and Simulation: An Interdisciplinary Guide by : Tamar Schlick

Download or read book Molecular Modeling and Simulation: An Interdisciplinary Guide written by Tamar Schlick and published by Springer Science & Business Media. This book was released on 2010-08-03 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: Very broad overview of the field intended for an interdisciplinary audience; Lively discussion of current challenges written in a colloquial style; Author is a rising star in this discipline; Suitably accessible for beginners and suitably rigorous for experts; Features extensive four-color illustrations; Appendices featuring homework assignments and reading lists complement the material in the main text

Handbook of Biochemical Kinetics

Handbook of Biochemical Kinetics

Author: Daniel L. Purich

Publisher: Elsevier

Published: 1999-10-26

Total Pages: 788

ISBN-13: 9780080521930

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Biochemical kinetics refers to the rate at which a reaction takes place. Kinetic mechanisms have played a major role in defining the metabolic pathways, the mechanistic action of enzymes, and even the processing of genetic material. The Handbook of Biochemical Kinetics provides the "underlying scaffolding" of logic for kinetic approaches to distinguish rival models or mechanisms. The handbook also comments on techniques and their likely limitations and pitfalls, as well as derivations of fundamental rate equations that characterize biochemical processes. Key Features * Over 750 pages devoted to theory and techniques for studying enzymic and metabolic processes * Over 1,500 definitions of kinetic and mechanistic terminology, with key references * Practical advice on experimental design of kinetic experiments * Extended step-by-step methods for deriving rate equations * Over 1,000 enzymes, complete with EC numbers, reactions catalyzed, and references to reviews and/or assay methods * Over 5,000 selected references to kinetic methods appearing in the Methods in Enzymology series * 72-page Wordfinder that allows the reader to search by keywords * Summaries of mechanistic studies on key enzymes and protein systems * Over 250 diagrams, figures, tables, and structures


Book Synopsis Handbook of Biochemical Kinetics by : Daniel L. Purich

Download or read book Handbook of Biochemical Kinetics written by Daniel L. Purich and published by Elsevier. This book was released on 1999-10-26 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical kinetics refers to the rate at which a reaction takes place. Kinetic mechanisms have played a major role in defining the metabolic pathways, the mechanistic action of enzymes, and even the processing of genetic material. The Handbook of Biochemical Kinetics provides the "underlying scaffolding" of logic for kinetic approaches to distinguish rival models or mechanisms. The handbook also comments on techniques and their likely limitations and pitfalls, as well as derivations of fundamental rate equations that characterize biochemical processes. Key Features * Over 750 pages devoted to theory and techniques for studying enzymic and metabolic processes * Over 1,500 definitions of kinetic and mechanistic terminology, with key references * Practical advice on experimental design of kinetic experiments * Extended step-by-step methods for deriving rate equations * Over 1,000 enzymes, complete with EC numbers, reactions catalyzed, and references to reviews and/or assay methods * Over 5,000 selected references to kinetic methods appearing in the Methods in Enzymology series * 72-page Wordfinder that allows the reader to search by keywords * Summaries of mechanistic studies on key enzymes and protein systems * Over 250 diagrams, figures, tables, and structures