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Blood Clotting Enzymology

Author: Walter H. Seegers

Publisher: Academic Press

Published: 2013-10-22

Total Pages: 641

ISBN-13: 1483225453

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Blood Clotting Enzymology covers the mechanisms of blood clotting and their role in thrombosis, hemostasis, and many associated ramifications. This book is composed of 12 chapters that consider the integration of knowledge on blood clotting enzymology with hemostasis physiology. The opening chapter deals with the enzymology of the sol-gel transformation was studied in terms of proteins, fats, carbohydrates, surface physics, immunology, biophysical mechanisms, structural architecture, vitamin K and its antagonists, and the rheology of the blood. The subsequent chapters review the biophysical properties and composition of active substance in blood coagulation, as well as the concepts of prothrombin activation. These topics are followed by discussions on the chemical and physicochemical properties of fibrinogen and fibrin; the application of immulogical methods to delineate important properties of plasma constituents; and the mechanisms of antithrombin activity. Other chapters tackle the importance of hirudin and cobra venom for certain experimental laboratory work in the study of the physiology of blood coagulation. The final chapters survey the role of platelets in hemostasis, bleeding disorders, and the chemistry and function of vitamin K in blood coagulation. This book will prove useful to hematologists, enzyme scientist, immunologists, and research workers who are interested in blood coagulation mechanisms.

Book Synopsis Blood Clotting Enzymology by : Walter H. Seegers

Download or read book Blood Clotting Enzymology written by Walter H. Seegers and published by Academic Press. This book was released on 2013-10-22 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood Clotting Enzymology covers the mechanisms of blood clotting and their role in thrombosis, hemostasis, and many associated ramifications. This book is composed of 12 chapters that consider the integration of knowledge on blood clotting enzymology with hemostasis physiology. The opening chapter deals with the enzymology of the sol-gel transformation was studied in terms of proteins, fats, carbohydrates, surface physics, immunology, biophysical mechanisms, structural architecture, vitamin K and its antagonists, and the rheology of the blood. The subsequent chapters review the biophysical properties and composition of active substance in blood coagulation, as well as the concepts of prothrombin activation. These topics are followed by discussions on the chemical and physicochemical properties of fibrinogen and fibrin; the application of immulogical methods to delineate important properties of plasma constituents; and the mechanisms of antithrombin activity. Other chapters tackle the importance of hirudin and cobra venom for certain experimental laboratory work in the study of the physiology of blood coagulation. The final chapters survey the role of platelets in hemostasis, bleeding disorders, and the chemistry and function of vitamin K in blood coagulation. This book will prove useful to hematologists, enzyme scientist, immunologists, and research workers who are interested in blood coagulation mechanisms.

Blood Clotting Enzymology, Edited by Walter H. Seegers. List of Contributors

Author: Walter Henry Seegers

Publisher:

Published: 1967

Total Pages: 628

ISBN-13:

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Book Synopsis Blood Clotting Enzymology, Edited by Walter H. Seegers. List of Contributors by : Walter Henry Seegers

Download or read book Blood Clotting Enzymology, Edited by Walter H. Seegers. List of Contributors written by Walter Henry Seegers and published by . This book was released on 1967 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Blood Coagulation

Author: R.F.A. Zwaal

Publisher: Elsevier

Published: 1986-01-01

Total Pages: 320

ISBN-13: 9780080860725

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This is the first book to give complete insight into the biochemistry of blood coagulation, and demonstrates how this field provides important contributions to fundamental biochemistry, such as enzyme kinetics, lipid-protein interactions, oxidative carboxylation, and cell receptors. The book will be of interest both to biochemists and molecular biologists who want to gain insight into the process of blood coagulation, as well as to those already working in the field of blood coagulation who desire to broaden their insight into its molecular aspects.

Book Synopsis Blood Coagulation by : R.F.A. Zwaal

Download or read book Blood Coagulation written by R.F.A. Zwaal and published by Elsevier. This book was released on 1986-01-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to give complete insight into the biochemistry of blood coagulation, and demonstrates how this field provides important contributions to fundamental biochemistry, such as enzyme kinetics, lipid-protein interactions, oxidative carboxylation, and cell receptors. The book will be of interest both to biochemists and molecular biologists who want to gain insight into the process of blood coagulation, as well as to those already working in the field of blood coagulation who desire to broaden their insight into its molecular aspects.

Fibrinolytic Bacterial Enzymes with Thrombolytic Activity

Author: Essam Kotb

Publisher: Springer Science & Business Media

Published: 2012-01-04

Total Pages: 85

ISBN-13: 3642249809

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Stress, high blood pressure, smoking, pollution, fast foods, overweight, excessive travelling, surgery, less movement are common features in our modern life. These features are risky for blood clotting disorders. According to WHO, over 29% of the total mortalities worldwide are due to thrombosis. By the year, 2020 cardiovascular diseases (CVDs) may cause an estimated 25 million deaths per year, thus antithrombotic therapy is of great interest. The available thrombolytic agents such as urokinase are highly expensive, antigenic, quite unspecific, pyretogenic and hemorrhagenic. Therefore, the production of fibrinolysing enzymes, which rapidly dissolute thrombi within the vascular tree, without the detriments by microorganisms, as described in this book, is the desirable aim of today’s research.

Book Synopsis Fibrinolytic Bacterial Enzymes with Thrombolytic Activity by : Essam Kotb

Download or read book Fibrinolytic Bacterial Enzymes with Thrombolytic Activity written by Essam Kotb and published by Springer Science & Business Media. This book was released on 2012-01-04 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress, high blood pressure, smoking, pollution, fast foods, overweight, excessive travelling, surgery, less movement are common features in our modern life. These features are risky for blood clotting disorders. According to WHO, over 29% of the total mortalities worldwide are due to thrombosis. By the year, 2020 cardiovascular diseases (CVDs) may cause an estimated 25 million deaths per year, thus antithrombotic therapy is of great interest. The available thrombolytic agents such as urokinase are highly expensive, antigenic, quite unspecific, pyretogenic and hemorrhagenic. Therefore, the production of fibrinolysing enzymes, which rapidly dissolute thrombi within the vascular tree, without the detriments by microorganisms, as described in this book, is the desirable aim of today’s research.

Hemostasis and Coagulation

Author: Jarrell D. Bairrington

Publisher:

Published: 1966

Total Pages: 40

ISBN-13:

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The review cites leading articles which deal directly with the formation of theories of coagulation as they exist today. Many of the papers cited were written because of a search for the cause and cure of hemophilia; therefore, this subject is dealt with in some length. (Author).

Book Synopsis Hemostasis and Coagulation by : Jarrell D. Bairrington

Download or read book Hemostasis and Coagulation written by Jarrell D. Bairrington and published by . This book was released on 1966 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: The review cites leading articles which deal directly with the formation of theories of coagulation as they exist today. Many of the papers cited were written because of a search for the cause and cure of hemophilia; therefore, this subject is dealt with in some length. (Author).

Chemistry of Thrombolysis

Author: Kurt Nikolai Kaulla

Publisher:

Published: 1963

Total Pages: 362

ISBN-13:

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Book Synopsis Chemistry of Thrombolysis by : Kurt Nikolai Kaulla

Download or read book Chemistry of Thrombolysis written by Kurt Nikolai Kaulla and published by . This book was released on 1963 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Blood Coagulation

Author: R. F. A. Zwaal

Publisher:

Published: 1986

Total Pages: 0

ISBN-13: 9780444803030

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Book Synopsis Blood Coagulation by : R. F. A. Zwaal

Download or read book Blood Coagulation written by R. F. A. Zwaal and published by . This book was released on 1986 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hemostasis in Dentistry

Author: Richard P. Szumita

Publisher: Springer

Published: 2018-08-06

Total Pages: 204

ISBN-13: 3319712403

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This book offers a thorough, clinically oriented review of hemostasis and its impact on the practice of dentistry. Readers will gain a sound understanding of the pathophysiology of hemostasis and the pharmacology of antithrombotic and prothrombotic medications. Perioperative dental management strategies of value in patients with different congenital and acquired disorders of hemostasis are carefully explained, and the role of surgical techniques and local and topical agents in helping to minimize and control bleeding is described. Helpful instruction is also provided on the indications for antithrombotic medications and the management of patients receiving such therapy, including the risks of altering medications. As the number of available oral antithrombotic agents continues to increase, dentists will encounter significantly more patients receiving treatments that affect hemostasis. In presenting comprehensive, up-to-date information on hemostasis, hemostatic disorders, antithrombotic therapy, and safe dental management, this book will serve as a rich source of information and a useful guide for practitioners and students alike.

Book Synopsis Hemostasis in Dentistry by : Richard P. Szumita

Download or read book Hemostasis in Dentistry written by Richard P. Szumita and published by Springer. This book was released on 2018-08-06 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a thorough, clinically oriented review of hemostasis and its impact on the practice of dentistry. Readers will gain a sound understanding of the pathophysiology of hemostasis and the pharmacology of antithrombotic and prothrombotic medications. Perioperative dental management strategies of value in patients with different congenital and acquired disorders of hemostasis are carefully explained, and the role of surgical techniques and local and topical agents in helping to minimize and control bleeding is described. Helpful instruction is also provided on the indications for antithrombotic medications and the management of patients receiving such therapy, including the risks of altering medications. As the number of available oral antithrombotic agents continues to increase, dentists will encounter significantly more patients receiving treatments that affect hemostasis. In presenting comprehensive, up-to-date information on hemostasis, hemostatic disorders, antithrombotic therapy, and safe dental management, this book will serve as a rich source of information and a useful guide for practitioners and students alike.

Enzyme Activation in Blood-Perfused Artificial Organs

Author: Holger Schmid-Schönbein

Publisher: Springer Science & Business Media

Published: 1984-12-31

Total Pages: 254

ISBN-13: 9780898387049

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Proceedings of an interdisciplinary meeting, sponsored by the Commission of the European Communities, as advised by the Committee on Medical and Public Health Research

Book Synopsis Enzyme Activation in Blood-Perfused Artificial Organs by : Holger Schmid-Schönbein

Download or read book Enzyme Activation in Blood-Perfused Artificial Organs written by Holger Schmid-Schönbein and published by Springer Science & Business Media. This book was released on 1984-12-31 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an interdisciplinary meeting, sponsored by the Commission of the European Communities, as advised by the Committee on Medical and Public Health Research

Structural Biology in Drug Discovery

Author: Jean-Paul Renaud

Publisher: John Wiley & Sons

Published: 2020-01-09

Total Pages: 1367

ISBN-13: 1118900502

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With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins

Book Synopsis Structural Biology in Drug Discovery by : Jean-Paul Renaud

Download or read book Structural Biology in Drug Discovery written by Jean-Paul Renaud and published by John Wiley & Sons. This book was released on 2020-01-09 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins