Blood flow specific assessment of ventricular function

Blood flow specific assessment of ventricular function

Author: Alexandru Grigorescu Fredriksson

Publisher: Linköping University Electronic Press

Published: 2017-12-06

Total Pages: 95

ISBN-13: 9176854159

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The spectrum of cardiovascular diseases is the leading cause of morbidity and mortality globally. Early assessment and treatment of these conditions, acquired as well as congenital, is therefore of paramount importance. The human heart has a great ability to adapt to various hemodynamic conditions by cardiac remodeling. Pathologic cardiac remodeling can occur as a result of cardiovascular disease in an effort to maintain satisfactory cardiac function. With time, cardiac function diminishes leading to disease progression and subsequent heart failure, the end-point of many heart diseases, associated with very poor prognosis. Within the normal cardiac ventricles blood flows in highly organized patterns, and changes in cardiac configuration or function will affect these flow patterns. Conversely, altered flows and pressures can bring about cardiac remodeling. In congenital heart disease, even after corrective surgery, cardiac anatomy and thereby intracardiac blood flow patterns are inherently altered. The clinically most available imaging technique, ultrasound with Doppler, allows only for one-directional flow assessment and is limited by the need of clear examination windows, thus failing to fully assess the complex three-dimensional blood flow within the beating heart. Cardiovascular magnetic resonance imaging (CMR) with phase-contrast has the ability to acquire three-dimensional (3D), three-directional time resolved velocity data (3D + time = 4D flow data) from which visualization and quantification of blood flow patterns over the complete cardiac cycle can be performed. Four functional blood flow components have previously been defined based on the blood route and distribution through the ventricle, where the inflowing blood that passes directly to the outflow is called Direct flow. From these components, various quantitative measures can be derived, such as component volumes and kinetic energy (KE) throughout the cardiac cycle. In addition, the 4D flow technique has the ability to quantify and visualize turbulent flow with increased velocity fluctuations in the heart and vessels, turbulent kinetic energy (TKE). The technique has been developed and evaluated for assessment of left ventricular (LV) blood flow in healthy subjects and in patients with dilated dysfunctional left ventricles, showing significant changes in blood flow patterns and energetics with disease. There is however still no study addressing the gap in the spectrum from the healthy cohorts to patients with moderate to severe left ventricular remodeling. In Paper III, 4D flow CMR was utilized to assess LV blood flow in patients with subtle LV dysfunction, and a shift in blood flow component volumes and KE was seen from the Direct flow to the non-ejecting blood flow components. In patients with both left- and right-sided acquired and congenital heart disease, right ventricular (RV) function is of great prognostic significance, however this ventricle has historically been somewhat overseen. With its complex geometry, advanced physiology and retrosternal location, assessment of the RV is still challenging and the right ventricular blood flow is still incompletely described. In Paper I, the RV blood flow in healthy subjects was assessed, and the proportionally larger Direct flow component was located in the most basal region of the ventricle and possessed higher levels of KE at end-diastole than the other flow components suggesting that this portion of blood was prepared for efficient systolic ejection. In Paper II, the blood flow was assessed in the RV of patients with subtle primary LV disease, and even if conventional echocardiographic or CMR RV parameters did not show any RV dysfunction, alterations of flow patterns suggestive of RV impairment were found in the patients with the more remodeled LVs. With improvements of the cardiovascular health care, including the surgical techniques, the number of adult patients with surgically corrected complex congenital heart diseases increases, one of which is tetralogy of Fallot (ToF). Surgical repair of ToF involves widening of the pulmonary stenosis, which postoperatively may cause pulmonary insufficiency and regurgitation (PR). Disturbed or turbulent flow patterns are rare in the healthy cardiovascular system. With pathological changes, such as valvular insufficiency, increased amounts of TKE have been demonstrated. Turbulence is known to be harmful to organic tissues and could be significant in the development of ventricular remodeling, such as dilation and other complications seen in Fallot patients. In Paper IV, the RV intraventricular TKE levels were assessed in relation to conventional measures of PR. Results showed that RV TKE was increased in ToF patients with PR compared to healthy controls, and that these 4D flow-specific measures related slightly stronger to indices of RV remodeling than the conventional measures of PR. 4D flow CMR analysis of the intracardiac blood flow has the potential of adding to pathophysiological understanding, and thereby provide useful diagnostic information and contribute to optimization of treatment of heart disease at earlier stages before irreversible and clinically noticeable changes occur. The flow specific measures used in this thesis could be utilized to detect these alterations of intracardiac blood flow and could thus act as potential markers of progressing ventricular dysfunction, pathological remodeling or used for risk stratification in adults with early repair tetralogy of Fallot. Visualizations of intracardiac flow patterns could provide useful information to cardiac/thoracic surgeons pre- and post-operatively.


Book Synopsis Blood flow specific assessment of ventricular function by : Alexandru Grigorescu Fredriksson

Download or read book Blood flow specific assessment of ventricular function written by Alexandru Grigorescu Fredriksson and published by Linköping University Electronic Press. This book was released on 2017-12-06 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: The spectrum of cardiovascular diseases is the leading cause of morbidity and mortality globally. Early assessment and treatment of these conditions, acquired as well as congenital, is therefore of paramount importance. The human heart has a great ability to adapt to various hemodynamic conditions by cardiac remodeling. Pathologic cardiac remodeling can occur as a result of cardiovascular disease in an effort to maintain satisfactory cardiac function. With time, cardiac function diminishes leading to disease progression and subsequent heart failure, the end-point of many heart diseases, associated with very poor prognosis. Within the normal cardiac ventricles blood flows in highly organized patterns, and changes in cardiac configuration or function will affect these flow patterns. Conversely, altered flows and pressures can bring about cardiac remodeling. In congenital heart disease, even after corrective surgery, cardiac anatomy and thereby intracardiac blood flow patterns are inherently altered. The clinically most available imaging technique, ultrasound with Doppler, allows only for one-directional flow assessment and is limited by the need of clear examination windows, thus failing to fully assess the complex three-dimensional blood flow within the beating heart. Cardiovascular magnetic resonance imaging (CMR) with phase-contrast has the ability to acquire three-dimensional (3D), three-directional time resolved velocity data (3D + time = 4D flow data) from which visualization and quantification of blood flow patterns over the complete cardiac cycle can be performed. Four functional blood flow components have previously been defined based on the blood route and distribution through the ventricle, where the inflowing blood that passes directly to the outflow is called Direct flow. From these components, various quantitative measures can be derived, such as component volumes and kinetic energy (KE) throughout the cardiac cycle. In addition, the 4D flow technique has the ability to quantify and visualize turbulent flow with increased velocity fluctuations in the heart and vessels, turbulent kinetic energy (TKE). The technique has been developed and evaluated for assessment of left ventricular (LV) blood flow in healthy subjects and in patients with dilated dysfunctional left ventricles, showing significant changes in blood flow patterns and energetics with disease. There is however still no study addressing the gap in the spectrum from the healthy cohorts to patients with moderate to severe left ventricular remodeling. In Paper III, 4D flow CMR was utilized to assess LV blood flow in patients with subtle LV dysfunction, and a shift in blood flow component volumes and KE was seen from the Direct flow to the non-ejecting blood flow components. In patients with both left- and right-sided acquired and congenital heart disease, right ventricular (RV) function is of great prognostic significance, however this ventricle has historically been somewhat overseen. With its complex geometry, advanced physiology and retrosternal location, assessment of the RV is still challenging and the right ventricular blood flow is still incompletely described. In Paper I, the RV blood flow in healthy subjects was assessed, and the proportionally larger Direct flow component was located in the most basal region of the ventricle and possessed higher levels of KE at end-diastole than the other flow components suggesting that this portion of blood was prepared for efficient systolic ejection. In Paper II, the blood flow was assessed in the RV of patients with subtle primary LV disease, and even if conventional echocardiographic or CMR RV parameters did not show any RV dysfunction, alterations of flow patterns suggestive of RV impairment were found in the patients with the more remodeled LVs. With improvements of the cardiovascular health care, including the surgical techniques, the number of adult patients with surgically corrected complex congenital heart diseases increases, one of which is tetralogy of Fallot (ToF). Surgical repair of ToF involves widening of the pulmonary stenosis, which postoperatively may cause pulmonary insufficiency and regurgitation (PR). Disturbed or turbulent flow patterns are rare in the healthy cardiovascular system. With pathological changes, such as valvular insufficiency, increased amounts of TKE have been demonstrated. Turbulence is known to be harmful to organic tissues and could be significant in the development of ventricular remodeling, such as dilation and other complications seen in Fallot patients. In Paper IV, the RV intraventricular TKE levels were assessed in relation to conventional measures of PR. Results showed that RV TKE was increased in ToF patients with PR compared to healthy controls, and that these 4D flow-specific measures related slightly stronger to indices of RV remodeling than the conventional measures of PR. 4D flow CMR analysis of the intracardiac blood flow has the potential of adding to pathophysiological understanding, and thereby provide useful diagnostic information and contribute to optimization of treatment of heart disease at earlier stages before irreversible and clinically noticeable changes occur. The flow specific measures used in this thesis could be utilized to detect these alterations of intracardiac blood flow and could thus act as potential markers of progressing ventricular dysfunction, pathological remodeling or used for risk stratification in adults with early repair tetralogy of Fallot. Visualizations of intracardiac flow patterns could provide useful information to cardiac/thoracic surgeons pre- and post-operatively.

Blood Flow Specific Assessment of Ventricular Function

Blood Flow Specific Assessment of Ventricular Function

Author: Alexandru Grigorescu Fredriksson

Publisher:

Published: 2017

Total Pages:

ISBN-13:

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The spectrum of cardiovascular diseases is the leading cause of morbidity and mortality globally. Early assessment and treatment of these conditions, acquired as well as congenital, is therefore of paramount importance. The human heart has a great ability to adapt to various hemodynamic conditions by cardiac remodeling. Pathologic cardiac remodeling can occur as a result of cardiovascular disease in an effort to maintain satisfactory cardiac function. With time, cardiac function diminishes leading to disease progression and subsequent heart failure, the end-point of many heart diseases, associated with very poor prognosis. Within the normal cardiac ventricles blood flows in highly organized patterns, and changes in cardiac configuration or function will affect these flow patterns. Conversely, altered flows and pressures can bring about cardiac remodeling. In congenital heart disease, even after corrective surgery, cardiac anatomy and thereby intracardiac blood flow patterns are inherently altered. The clinically most available imaging technique, ultrasound with Doppler, allows only for one-directional flow assessment and is limited by the need of clear examination windows, thus failing to fully assess the complex three-dimensional blood flow within the beating heart. Cardiovascular magnetic resonance imaging (CMR) with phase-contrast has the ability to acquire three-dimensional (3D), three-directional time resolved velocity data (3D + time = 4D flow data) from which visualization and quantification of blood flow patterns over the complete cardiac cycle can be performed. Four functional blood flow components have previously been defined based on the blood route and distribution through the ventricle, where the inflowing blood that passes directly to the outflow is called Direct flow . From these components, various quantitative measures can be derived, such as component volumes and kinetic energy (KE) throughout the cardiac cycle. In addition, the 4D flow technique has the ability to quantify and visualize turbulent flow with increased velocity fluctuations in the heart and vessels, turbulent kinetic energy (TKE). The technique has been developed and evaluated for assessment of left ventricular (LV) blood flow in healthy subjects and in patients with dilated dysfunctional left ventricles, showing significant changes in blood flow patterns and energetics with disease. There is however still no study addressing the gap in the spectrum from the healthy cohorts to patients with moderate to severe left ventricular remodeling. In Paper III , 4D flow CMR was utilized to assess LV blood flow in patients with subtle LV dysfunction, and a shift in blood flow component volumes and KE was seen from the Direct flow to the non-ejecting blood flow components. In patients with both left- and right-sided acquired and congenital heart disease, right ventricular (RV) function is of great prognostic significance, however this ventricle has historically been somewhat overseen. With its complex geometry, advanced physiology and retrosternal location, assessment of the RV is still challenging and the right ventricular blood flow is still incompletely described. In Paper I , the RV blood flow in healthy subjects was assessed, and the proportionally larger Direct flow component was located in the most basal region of the ventricle and possessed higher levels of KE at end-diastole than the other flow components suggesting that this portion of blood was prepared for efficient systolic ejection. In Paper II , the blood flow was assessed in the RV of patients with subtle primary LV disease, and even if conventional echocardiographic or CMR RV parameters did not show any RV dysfunction, alterations of flow patterns suggestive of RV impairment were found in the patients with the more remodeled LVs. With improvements of the cardiovascular health care, including the surgical techniques, the number of adult patients with surgically corrected complex congenital heart diseases increases, one of which is tetralogy of Fallot (ToF). Surgical repair of ToF involves widening of the pulmonary stenosis, which postoperatively may cause pulmonary insufficiency and regurgitation (PR). Disturbed or turbulent flow patterns are rare in the healthy cardiovascular system. With pathological changes, such as valvular insufficiency, increased amounts of TKE have been demonstrated. Turbulence is known to be harmful to organic tissues and could be significant in the development of ventricular remodeling, such as dilation and other complications seen in Fallot patients. In Paper IV , the RV intraventricular TKE levels were assessed in relation to conventional measures of PR. Results showed that RV TKE was increased in ToF patients with PR compared to healthy controls, and that these 4D flow-specific measures related slightly stronger to indices of RV remodeling than the conventional measures of PR. 4D flow CMR analysis of the intracardiac blood flow has the potential of adding to pathophysiological understanding, and thereby provide useful diagnostic information and contribute to optimization of treatment of heart disease at earlier stages before irreversible and clinically noticeable changes occur. The flow specific measures used in this thesis could be utilized to detect these alterations of intracardiac blood flow and could thus act as potential markers of progressing ventricular dysfunction, pathological remodeling or used for risk stratification in adults with early repair tetralogy of Fallot. Visualizations of intracardiac flow patterns could provide useful information to cardiac/thoracic surgeons pre- and post-operatively.


Book Synopsis Blood Flow Specific Assessment of Ventricular Function by : Alexandru Grigorescu Fredriksson

Download or read book Blood Flow Specific Assessment of Ventricular Function written by Alexandru Grigorescu Fredriksson and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The spectrum of cardiovascular diseases is the leading cause of morbidity and mortality globally. Early assessment and treatment of these conditions, acquired as well as congenital, is therefore of paramount importance. The human heart has a great ability to adapt to various hemodynamic conditions by cardiac remodeling. Pathologic cardiac remodeling can occur as a result of cardiovascular disease in an effort to maintain satisfactory cardiac function. With time, cardiac function diminishes leading to disease progression and subsequent heart failure, the end-point of many heart diseases, associated with very poor prognosis. Within the normal cardiac ventricles blood flows in highly organized patterns, and changes in cardiac configuration or function will affect these flow patterns. Conversely, altered flows and pressures can bring about cardiac remodeling. In congenital heart disease, even after corrective surgery, cardiac anatomy and thereby intracardiac blood flow patterns are inherently altered. The clinically most available imaging technique, ultrasound with Doppler, allows only for one-directional flow assessment and is limited by the need of clear examination windows, thus failing to fully assess the complex three-dimensional blood flow within the beating heart. Cardiovascular magnetic resonance imaging (CMR) with phase-contrast has the ability to acquire three-dimensional (3D), three-directional time resolved velocity data (3D + time = 4D flow data) from which visualization and quantification of blood flow patterns over the complete cardiac cycle can be performed. Four functional blood flow components have previously been defined based on the blood route and distribution through the ventricle, where the inflowing blood that passes directly to the outflow is called Direct flow . From these components, various quantitative measures can be derived, such as component volumes and kinetic energy (KE) throughout the cardiac cycle. In addition, the 4D flow technique has the ability to quantify and visualize turbulent flow with increased velocity fluctuations in the heart and vessels, turbulent kinetic energy (TKE). The technique has been developed and evaluated for assessment of left ventricular (LV) blood flow in healthy subjects and in patients with dilated dysfunctional left ventricles, showing significant changes in blood flow patterns and energetics with disease. There is however still no study addressing the gap in the spectrum from the healthy cohorts to patients with moderate to severe left ventricular remodeling. In Paper III , 4D flow CMR was utilized to assess LV blood flow in patients with subtle LV dysfunction, and a shift in blood flow component volumes and KE was seen from the Direct flow to the non-ejecting blood flow components. In patients with both left- and right-sided acquired and congenital heart disease, right ventricular (RV) function is of great prognostic significance, however this ventricle has historically been somewhat overseen. With its complex geometry, advanced physiology and retrosternal location, assessment of the RV is still challenging and the right ventricular blood flow is still incompletely described. In Paper I , the RV blood flow in healthy subjects was assessed, and the proportionally larger Direct flow component was located in the most basal region of the ventricle and possessed higher levels of KE at end-diastole than the other flow components suggesting that this portion of blood was prepared for efficient systolic ejection. In Paper II , the blood flow was assessed in the RV of patients with subtle primary LV disease, and even if conventional echocardiographic or CMR RV parameters did not show any RV dysfunction, alterations of flow patterns suggestive of RV impairment were found in the patients with the more remodeled LVs. With improvements of the cardiovascular health care, including the surgical techniques, the number of adult patients with surgically corrected complex congenital heart diseases increases, one of which is tetralogy of Fallot (ToF). Surgical repair of ToF involves widening of the pulmonary stenosis, which postoperatively may cause pulmonary insufficiency and regurgitation (PR). Disturbed or turbulent flow patterns are rare in the healthy cardiovascular system. With pathological changes, such as valvular insufficiency, increased amounts of TKE have been demonstrated. Turbulence is known to be harmful to organic tissues and could be significant in the development of ventricular remodeling, such as dilation and other complications seen in Fallot patients. In Paper IV , the RV intraventricular TKE levels were assessed in relation to conventional measures of PR. Results showed that RV TKE was increased in ToF patients with PR compared to healthy controls, and that these 4D flow-specific measures related slightly stronger to indices of RV remodeling than the conventional measures of PR. 4D flow CMR analysis of the intracardiac blood flow has the potential of adding to pathophysiological understanding, and thereby provide useful diagnostic information and contribute to optimization of treatment of heart disease at earlier stages before irreversible and clinically noticeable changes occur. The flow specific measures used in this thesis could be utilized to detect these alterations of intracardiac blood flow and could thus act as potential markers of progressing ventricular dysfunction, pathological remodeling or used for risk stratification in adults with early repair tetralogy of Fallot. Visualizations of intracardiac flow patterns could provide useful information to cardiac/thoracic surgeons pre- and post-operatively.

Ventricular Function and Blood Flow in Congenital Heart Disease

Ventricular Function and Blood Flow in Congenital Heart Disease

Author: Mark A. Fogel

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 392

ISBN-13: 1405173491

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Infants, children and adolescents with congenital heart disease(CHD) are a challenge to manage and an ever-increasing number arereaching adulthood. CHD is one of the most important topics in cardiology today, yetthis book is the only clinically-orientated monograph devotedexclusively to ventricular function and blood flow as it relates toCHD. Written by a distinguished panel of cardiologists, bioengineers,physiologists, and clinical investigators, Ventricular Functionand Blood Flow in Congenital Heart Disease is an extensive andcomprehensive presentation of the key aspects of this branch ofCHD.


Book Synopsis Ventricular Function and Blood Flow in Congenital Heart Disease by : Mark A. Fogel

Download or read book Ventricular Function and Blood Flow in Congenital Heart Disease written by Mark A. Fogel and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infants, children and adolescents with congenital heart disease(CHD) are a challenge to manage and an ever-increasing number arereaching adulthood. CHD is one of the most important topics in cardiology today, yetthis book is the only clinically-orientated monograph devotedexclusively to ventricular function and blood flow as it relates toCHD. Written by a distinguished panel of cardiologists, bioengineers,physiologists, and clinical investigators, Ventricular Functionand Blood Flow in Congenital Heart Disease is an extensive andcomprehensive presentation of the key aspects of this branch ofCHD.

Analysis and Assessment of Cardiovascular Function

Analysis and Assessment of Cardiovascular Function

Author: Gary M. Drzewiecki

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 390

ISBN-13: 146121744X

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The objective of this book is to provide the researcher and clinician with the recent developments in the analysis and assessment of cardiovascular func tion. The chapters are organized into sections that correspond with the various anatomical levels of the cardiovascular system. To a large extent, recent focus on the cardiovascular system function has been directed at the molecular level to the near exclusion of the tissue and organ function. While this may be useful in developing new therapeutic drugs, it does not aid the cardiologist or surgeon, who routinely deal with patient symptoms. This book integrates the micro-level and organ-level function so that new infor mation may be assimilated into the cardiovascular system as a whole. Within each section, the chapters have been arranged to progress from recent theoretical developments, to experimental research, and finally to clinical applications. This approach facilitates the timely transfer of infor mation from basic research to the clinic. The strength of the analytical approach will be evident to the reader. The theoretical analysis offers guidance to experimental design and, in some cases, offers solutions where measurements are as yet unattainable. In moving from newly attained knowledge to clinical practice, this book emphasizes the noninvasive meth in the future as technological advances ods. Such methods are desirable occur and the trend towards early preventive diagnosis is sought. What follows are highlights of new developments covered in each section of the book.


Book Synopsis Analysis and Assessment of Cardiovascular Function by : Gary M. Drzewiecki

Download or read book Analysis and Assessment of Cardiovascular Function written by Gary M. Drzewiecki and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to provide the researcher and clinician with the recent developments in the analysis and assessment of cardiovascular func tion. The chapters are organized into sections that correspond with the various anatomical levels of the cardiovascular system. To a large extent, recent focus on the cardiovascular system function has been directed at the molecular level to the near exclusion of the tissue and organ function. While this may be useful in developing new therapeutic drugs, it does not aid the cardiologist or surgeon, who routinely deal with patient symptoms. This book integrates the micro-level and organ-level function so that new infor mation may be assimilated into the cardiovascular system as a whole. Within each section, the chapters have been arranged to progress from recent theoretical developments, to experimental research, and finally to clinical applications. This approach facilitates the timely transfer of infor mation from basic research to the clinic. The strength of the analytical approach will be evident to the reader. The theoretical analysis offers guidance to experimental design and, in some cases, offers solutions where measurements are as yet unattainable. In moving from newly attained knowledge to clinical practice, this book emphasizes the noninvasive meth in the future as technological advances ods. Such methods are desirable occur and the trend towards early preventive diagnosis is sought. What follows are highlights of new developments covered in each section of the book.

Ventricular Function

Ventricular Function

Author: David C. Warltier

Publisher: Lippincott Williams & Wilkins

Published: 1995

Total Pages: 404

ISBN-13:

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Book Synopsis Ventricular Function by : David C. Warltier

Download or read book Ventricular Function written by David C. Warltier and published by Lippincott Williams & Wilkins. This book was released on 1995 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Assessment of Ventricular Function

Assessment of Ventricular Function

Author: Angelo Raineri

Publisher: Springer Science & Business Media

Published: 2013-11-27

Total Pages: 341

ISBN-13: 1468480030

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This is the 3rd Course that has been organized at the presti gious E. Majorana Centre. The choice of the theme is not a casual one. In fact after rehabilitation and prevention which were the topics discussed in the previous courses of 1979 and 1982, this Course deals with subjects more deeply connected with the mechanisms of cardiac function and the pathological aspects that under this point of view characterize many specific diseases. The rapid development in the application of technology to the problems of Cardiological diagnosis has made it possible to study ventricular function in the evaluation of patients with apparent or suspected heart disease. Knowing that we are facing one of the most complex subjects in modern cardiology we wish to arouse the interest of researchers anrl cardiologists by comparing different experiences with the aim of giving an overall survey of the problems. The program has been divided into 4 chapters: 1. Systolic and diastolic ventricular function. 2. Specific studies of ventricular function using invasive and non invasive techniques. 3. Diseases with altered ventricular function. 4. Pharmacological manipulation of ventricular function. Our aim is not only to stimulate useful discussions in the faculty but also among the participants. I hope that we can achieve this. I should like to take this opportunity of thanking the co directors of the Course Prof. Jan Kellermann and Prof. Robert v vi PREFACE Leachman who have played an important part in the scientific organization.


Book Synopsis Assessment of Ventricular Function by : Angelo Raineri

Download or read book Assessment of Ventricular Function written by Angelo Raineri and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the 3rd Course that has been organized at the presti gious E. Majorana Centre. The choice of the theme is not a casual one. In fact after rehabilitation and prevention which were the topics discussed in the previous courses of 1979 and 1982, this Course deals with subjects more deeply connected with the mechanisms of cardiac function and the pathological aspects that under this point of view characterize many specific diseases. The rapid development in the application of technology to the problems of Cardiological diagnosis has made it possible to study ventricular function in the evaluation of patients with apparent or suspected heart disease. Knowing that we are facing one of the most complex subjects in modern cardiology we wish to arouse the interest of researchers anrl cardiologists by comparing different experiences with the aim of giving an overall survey of the problems. The program has been divided into 4 chapters: 1. Systolic and diastolic ventricular function. 2. Specific studies of ventricular function using invasive and non invasive techniques. 3. Diseases with altered ventricular function. 4. Pharmacological manipulation of ventricular function. Our aim is not only to stimulate useful discussions in the faculty but also among the participants. I hope that we can achieve this. I should like to take this opportunity of thanking the co directors of the Course Prof. Jan Kellermann and Prof. Robert v vi PREFACE Leachman who have played an important part in the scientific organization.

Ventricular Diastolic Function

Ventricular Diastolic Function

Author: Bernard Bulwer

Publisher:

Published: 2022-01-16

Total Pages: 351

ISBN-13:

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FEATURES: 351 pages, > 2,000 Illustrations and Images. Publication date: Jan 16, 2022. 1.Cardiac Structure and Diastolic Function 2.Cardiac Cycle, Atrio-Ventricular Events, and Diastolic Function 3.Blood Flow Hemodynamics, Cardiac Mechanics, and Diastolic Function 4.Echo Physics and Techniques Employed in Diastolic Function Assessment 5.Echocardiographic Measures of Ventricular Diastolic Function: ASE - EACVI 6.Left Atrial Phasic Function and Echo-Correlates 7.Left Ventricular Diastolic Function, Filling Pressures, and Echo-Correlates 8.Right Heart Function and Echo-Correlates of Right Heart and Pulmonary Artery Pressures 9.Patho-Physiology of Diastolic Function and Dysfunction 10.Key Criteria for the Diagnosis of LV Diastolic Dysfunction with Normal EF 11.Algorithm for LV Filling Pressures with Depressed EF and Myocardial Disease 12.Grades of Diastolic Dysfunction 13.Echocardiographic Perspectives in Heart Failure with Preserved and Reduced LV Ejection Fraction: HFpEF and HFrEF


Book Synopsis Ventricular Diastolic Function by : Bernard Bulwer

Download or read book Ventricular Diastolic Function written by Bernard Bulwer and published by . This book was released on 2022-01-16 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: FEATURES: 351 pages, > 2,000 Illustrations and Images. Publication date: Jan 16, 2022. 1.Cardiac Structure and Diastolic Function 2.Cardiac Cycle, Atrio-Ventricular Events, and Diastolic Function 3.Blood Flow Hemodynamics, Cardiac Mechanics, and Diastolic Function 4.Echo Physics and Techniques Employed in Diastolic Function Assessment 5.Echocardiographic Measures of Ventricular Diastolic Function: ASE - EACVI 6.Left Atrial Phasic Function and Echo-Correlates 7.Left Ventricular Diastolic Function, Filling Pressures, and Echo-Correlates 8.Right Heart Function and Echo-Correlates of Right Heart and Pulmonary Artery Pressures 9.Patho-Physiology of Diastolic Function and Dysfunction 10.Key Criteria for the Diagnosis of LV Diastolic Dysfunction with Normal EF 11.Algorithm for LV Filling Pressures with Depressed EF and Myocardial Disease 12.Grades of Diastolic Dysfunction 13.Echocardiographic Perspectives in Heart Failure with Preserved and Reduced LV Ejection Fraction: HFpEF and HFrEF

Handbook of Contrast Echocardiography

Handbook of Contrast Echocardiography

Author: Harald Becher

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 317

ISBN-13: 3642597483

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Although the technology required for the successful application of contrast echo cardiography has evolved rapidly over the past few years, the technique has not yet gained widespread clinical acceptance. One important reason for the lack of clinical acceptance is the relative complexity of the technique, particularly in respect to myocardial perfusion imaging. The interaction between micro bubbles and ultrasound is an entire field by itsel£ as is the coronary microvasculature. It is in this regard that practicing echocardiographers, cardiologists in training, radiologists, so no graphers, and students will find 'A Handbook of Contrast Echocardiography' particularly useful. Written by two leaders in the field who have presented illustrative cases not only from their own laboratories but also from others around the world, this volume is a lucid, concise, and practical guide for the day-to-day use of contrast echocardiography. Dr Peter Burns has been involved in almost all the technical advances in the imaging methods that have made it possible to detect opacification of the left ventricular cavity and myocardium from a venous injection of microbubbles. He has been responsible to a large degree for advancing our understanding of the interaction between micro bubbles and ultrasound, which he describes in clear and easy to understand terms in this book. Dr Harald Becher has been active in the clincal application of contrast echocardiography for several years and has gained considerable experience with many imaging techniques and microbubbles, which he describes in this volume in some detail.


Book Synopsis Handbook of Contrast Echocardiography by : Harald Becher

Download or read book Handbook of Contrast Echocardiography written by Harald Becher and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the technology required for the successful application of contrast echo cardiography has evolved rapidly over the past few years, the technique has not yet gained widespread clinical acceptance. One important reason for the lack of clinical acceptance is the relative complexity of the technique, particularly in respect to myocardial perfusion imaging. The interaction between micro bubbles and ultrasound is an entire field by itsel£ as is the coronary microvasculature. It is in this regard that practicing echocardiographers, cardiologists in training, radiologists, so no graphers, and students will find 'A Handbook of Contrast Echocardiography' particularly useful. Written by two leaders in the field who have presented illustrative cases not only from their own laboratories but also from others around the world, this volume is a lucid, concise, and practical guide for the day-to-day use of contrast echocardiography. Dr Peter Burns has been involved in almost all the technical advances in the imaging methods that have made it possible to detect opacification of the left ventricular cavity and myocardium from a venous injection of microbubbles. He has been responsible to a large degree for advancing our understanding of the interaction between micro bubbles and ultrasound, which he describes in clear and easy to understand terms in this book. Dr Harald Becher has been active in the clincal application of contrast echocardiography for several years and has gained considerable experience with many imaging techniques and microbubbles, which he describes in this volume in some detail.

The Breathless Heart

The Breathless Heart

Author: Michele Emdin

Publisher: Springer

Published: 2016-11-25

Total Pages: 288

ISBN-13: 3319263544

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This book systematically focuses on central sleep apneas, analyzing their relationship especially with heart failure and discussing recent research results and emerging treatment strategies based on feedback modulation. The opening chapters present historical background information on Cheyne-Stokes respiration (CSR), clarify terminology, and explain the mechanics and chemistry of respiration. Following a description of the physiology of respiration, the pathophysiology underlying central apneas in different disorders and particularly in heart failure is discussed. The similarities and differences of obstructive and central apneas are then considered. The book looks beyond the concept of sleep apnea to daytime CSR and periodic breathing during effort and contrasts the opposing views of CSR as a compensatory phenomenon or as detrimental to the failing heart. The diagnostic tools currently in use for the detection of CSR are thoroughly reviewed, with guidance on interpretation of findings. The book concludes by describing the various forms of treatment that are available for CSR and by explaining how to select patients for treatment.


Book Synopsis The Breathless Heart by : Michele Emdin

Download or read book The Breathless Heart written by Michele Emdin and published by Springer. This book was released on 2016-11-25 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systematically focuses on central sleep apneas, analyzing their relationship especially with heart failure and discussing recent research results and emerging treatment strategies based on feedback modulation. The opening chapters present historical background information on Cheyne-Stokes respiration (CSR), clarify terminology, and explain the mechanics and chemistry of respiration. Following a description of the physiology of respiration, the pathophysiology underlying central apneas in different disorders and particularly in heart failure is discussed. The similarities and differences of obstructive and central apneas are then considered. The book looks beyond the concept of sleep apnea to daytime CSR and periodic breathing during effort and contrasts the opposing views of CSR as a compensatory phenomenon or as detrimental to the failing heart. The diagnostic tools currently in use for the detection of CSR are thoroughly reviewed, with guidance on interpretation of findings. The book concludes by describing the various forms of treatment that are available for CSR and by explaining how to select patients for treatment.

Three-dimensional Echocardiography

Three-dimensional Echocardiography

Author: Navin Chandar Nanda

Publisher:

Published: 2007

Total Pages: 0

ISBN-13: 9781416042822

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Book Synopsis Three-dimensional Echocardiography by : Navin Chandar Nanda

Download or read book Three-dimensional Echocardiography written by Navin Chandar Nanda and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: