Calcium Signalling in Alzheimer’s Disease

Calcium Signalling in Alzheimer’s Disease

Author: Mounia Chami

Publisher: MDPI

Published: 2021-04-22

Total Pages: 162

ISBN-13: 3036504982

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Alzheimer’s disease (AD) is the most well-known neurodegenerative disorder, causing dementia. In recent decades, several studies have reported calcium dysregulation in AD occurring through the intervention of several calcium receptors and channels, and affecting different cellular compartments, such as mitochondria, the endoplasmic reticulum, lysosomes, and microdomains within the plasma membrane. Calcium signalling dysregulation is now considered a common proximal cause of dysfunctional neurons and glial supporting cells. This book gathers the newest results and advances in calcium signaling deregulation mechanisms in AD, how they are linked to other players involved in AD, and the potential therapies targeting calcium alterations to treat AD.


Book Synopsis Calcium Signalling in Alzheimer’s Disease by : Mounia Chami

Download or read book Calcium Signalling in Alzheimer’s Disease written by Mounia Chami and published by MDPI. This book was released on 2021-04-22 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease (AD) is the most well-known neurodegenerative disorder, causing dementia. In recent decades, several studies have reported calcium dysregulation in AD occurring through the intervention of several calcium receptors and channels, and affecting different cellular compartments, such as mitochondria, the endoplasmic reticulum, lysosomes, and microdomains within the plasma membrane. Calcium signalling dysregulation is now considered a common proximal cause of dysfunctional neurons and glial supporting cells. This book gathers the newest results and advances in calcium signaling deregulation mechanisms in AD, how they are linked to other players involved in AD, and the potential therapies targeting calcium alterations to treat AD.


Calcium Signalling and Disease

Calcium Signalling and Disease

Author: Ernesto Carafoli

Publisher: Springer

Published: 2010-11-20

Total Pages: 0

ISBN-13: 9789048175604

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Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.


Book Synopsis Calcium Signalling and Disease by : Ernesto Carafoli

Download or read book Calcium Signalling and Disease written by Ernesto Carafoli and published by Springer. This book was released on 2010-11-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.


Calcium Signaling: From Physiology to Diseases

Calcium Signaling: From Physiology to Diseases

Author: Senthilkumar Rajagopal

Publisher: Springer

Published: 2017-09-28

Total Pages: 91

ISBN-13: 9811051607

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This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities. In particular, it discusses the role of various natural products and their attributes in preventing problems associated with calcium imbalances. In addition, the book analyzes trends in the processing of natural products using nanotechnology and their implications in calcium-related disorders. Lastly, it explores some of the most promising aspects of research into calcium signalling disorders – which is especially important, given the wide variety of cellular processes that are controlled by calcium ions – and provides a trustworthy source of up-to-date information in this area of research.


Book Synopsis Calcium Signaling: From Physiology to Diseases by : Senthilkumar Rajagopal

Download or read book Calcium Signaling: From Physiology to Diseases written by Senthilkumar Rajagopal and published by Springer. This book was released on 2017-09-28 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities. In particular, it discusses the role of various natural products and their attributes in preventing problems associated with calcium imbalances. In addition, the book analyzes trends in the processing of natural products using nanotechnology and their implications in calcium-related disorders. Lastly, it explores some of the most promising aspects of research into calcium signalling disorders – which is especially important, given the wide variety of cellular processes that are controlled by calcium ions – and provides a trustworthy source of up-to-date information in this area of research.


Calcium Homeostasis and Signaling in Aging

Calcium Homeostasis and Signaling in Aging

Author: M.P. Mattson

Publisher:

Published: 2002-10

Total Pages: 222

ISBN-13:

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This volume of Advances in Cell Aging and Gerontology reviews the mechanisms that regulate cellular calcium homeostasis in various tissues throughout the body and how these systems change during aging. Normal functions of calcium in regulating various physiological processes are considered and the evidence supporting roles for perturbed calcium regulation in the pathogenesis of several prominent age-related disorders are detailed. The cross-disciplinary approach used to organize this book should provide readers interested in a specific area of calcium regulation with a broader perspective and a framework for which to shape future studies in their laboratories.


Book Synopsis Calcium Homeostasis and Signaling in Aging by : M.P. Mattson

Download or read book Calcium Homeostasis and Signaling in Aging written by M.P. Mattson and published by . This book was released on 2002-10 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Advances in Cell Aging and Gerontology reviews the mechanisms that regulate cellular calcium homeostasis in various tissues throughout the body and how these systems change during aging. Normal functions of calcium in regulating various physiological processes are considered and the evidence supporting roles for perturbed calcium regulation in the pathogenesis of several prominent age-related disorders are detailed. The cross-disciplinary approach used to organize this book should provide readers interested in a specific area of calcium regulation with a broader perspective and a framework for which to shape future studies in their laboratories.


Capacitative Calcium Entry

Capacitative Calcium Entry

Author: James W. Putney

Publisher: Springer

Published: 1997-06-15

Total Pages: 238

ISBN-13:

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Book Synopsis Capacitative Calcium Entry by : James W. Putney

Download or read book Capacitative Calcium Entry written by James W. Putney and published by Springer. This book was released on 1997-06-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167

Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167

Author: Bernd Nilius

Publisher: Springer

Published: 2014-11-18

Total Pages: 143

ISBN-13: 3319119214

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The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.


Book Synopsis Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167 by : Bernd Nilius

Download or read book Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167 written by Bernd Nilius and published by Springer. This book was released on 2014-11-18 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.


Calcium Signalling in Cancer

Calcium Signalling in Cancer

Author: G. V. Sherbet

Publisher: CRC Press

Published: 2000-11-29

Total Pages: 384

ISBN-13: 9780849309427

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Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an important feature of cell adhesion and motility; the integrity of the calcium binding proteins themselves is a basic requirement of normal biological function. In fact, the deregulation of calcium signaling is now regarded as the primary event in the pathogenesis, growth, invasion, and secondary spread of cancer. Calcium Signalling in Cancer is a concise up-to-date treatise on the transduction signals induced by calcium that considers how alterations in this calcium-dependent signal transduction pathway are related to a number of human diseases, especially neoplastic transformation. This authoritative text examines a broad range of topics-from mechanisms and significance of calcium homeostasis for normal cell function to calcium signalling pathways and the transduction of the calcium signal, especially in proliferation, cell motility, cancer invasion,, and metastasis. Clearly organized, it covers all aspects of the subject including specific sections on the regulation of the genes whose products are required for signal transduction by calcium, such as Alzheimer's disease, Darier's disease, Duchenne and limb girdle dystrophies, psoriasis and some forms of ichthyosis, and cancer associated retinopathy. With an extensive bibliography and over 2,500 references, Calcium Signalling in Cancer is an invaluable reference source.


Book Synopsis Calcium Signalling in Cancer by : G. V. Sherbet

Download or read book Calcium Signalling in Cancer written by G. V. Sherbet and published by CRC Press. This book was released on 2000-11-29 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an important feature of cell adhesion and motility; the integrity of the calcium binding proteins themselves is a basic requirement of normal biological function. In fact, the deregulation of calcium signaling is now regarded as the primary event in the pathogenesis, growth, invasion, and secondary spread of cancer. Calcium Signalling in Cancer is a concise up-to-date treatise on the transduction signals induced by calcium that considers how alterations in this calcium-dependent signal transduction pathway are related to a number of human diseases, especially neoplastic transformation. This authoritative text examines a broad range of topics-from mechanisms and significance of calcium homeostasis for normal cell function to calcium signalling pathways and the transduction of the calcium signal, especially in proliferation, cell motility, cancer invasion,, and metastasis. Clearly organized, it covers all aspects of the subject including specific sections on the regulation of the genes whose products are required for signal transduction by calcium, such as Alzheimer's disease, Darier's disease, Duchenne and limb girdle dystrophies, psoriasis and some forms of ichthyosis, and cancer associated retinopathy. With an extensive bibliography and over 2,500 references, Calcium Signalling in Cancer is an invaluable reference source.


Calcium Signaling in Biology and Medicine

Calcium Signaling in Biology and Medicine

Author: Mylo Sanders

Publisher: American Medical Publishers

Published: 2023-09-26

Total Pages: 0

ISBN-13: 9781639276110

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The process that increases low cytoplasmic concentrations in order to activate specific, essential events required by the cell is defined as calcium signaling. It uses calcium ions (Ca2+) to communicate and carry out intracellular processes often as a step in signal transduction. Calcium signaling plays a crucial role in the regulation of a diverse set of essential functions within the human body. The management of various neurodegenerative disorders such as Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease (PD) requires calcium signaling. It has been observed that disruption in calcium signaling may lead to synaptic deficits which further leads to accumulation of Aβ plaques and neurofibrillary tangles. Calcium plays an important role in various biological processes and calcium signaling has been linked to various diseases. Therefore, it is currently being explored as a therapeutic target for various types of cancer. This book elucidates the concepts and innovative models around prospective developments with respect to the importance of calcium signaling in biology and medicine. It will serve as a valuable source of reference for those interested in this field of study.


Book Synopsis Calcium Signaling in Biology and Medicine by : Mylo Sanders

Download or read book Calcium Signaling in Biology and Medicine written by Mylo Sanders and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The process that increases low cytoplasmic concentrations in order to activate specific, essential events required by the cell is defined as calcium signaling. It uses calcium ions (Ca2+) to communicate and carry out intracellular processes often as a step in signal transduction. Calcium signaling plays a crucial role in the regulation of a diverse set of essential functions within the human body. The management of various neurodegenerative disorders such as Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease (PD) requires calcium signaling. It has been observed that disruption in calcium signaling may lead to synaptic deficits which further leads to accumulation of Aβ plaques and neurofibrillary tangles. Calcium plays an important role in various biological processes and calcium signaling has been linked to various diseases. Therefore, it is currently being explored as a therapeutic target for various types of cancer. This book elucidates the concepts and innovative models around prospective developments with respect to the importance of calcium signaling in biology and medicine. It will serve as a valuable source of reference for those interested in this field of study.


Calcium Signaling

Calcium Signaling

Author: Geert Bultynck

Publisher:

Published: 2019

Total Pages:

ISBN-13: 9781621823889

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"Calcium ions play a critical role in signaling in a wide variety of cells and tissues, including muscle, immune cells, neurons, the liver, and oocytes. This new volume explores the channels and pumps that transport calcium, calcium buffers and sensors, and how these produce distinct spatiotemporal signals in different circumstances. It covers calcium signaling during development and normal physiology, as well as perturbed signaling in diseases such as diabetes, neurodegeneration, and atherosclerosis"--


Book Synopsis Calcium Signaling by : Geert Bultynck

Download or read book Calcium Signaling written by Geert Bultynck and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Calcium ions play a critical role in signaling in a wide variety of cells and tissues, including muscle, immune cells, neurons, the liver, and oocytes. This new volume explores the channels and pumps that transport calcium, calcium buffers and sensors, and how these produce distinct spatiotemporal signals in different circumstances. It covers calcium signaling during development and normal physiology, as well as perturbed signaling in diseases such as diabetes, neurodegeneration, and atherosclerosis"--


Brain Aging

Brain Aging

Author: David R. Riddle

Publisher: CRC Press

Published: 2007-04-19

Total Pages: 408

ISBN-13: 9781420005523

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Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur


Book Synopsis Brain Aging by : David R. Riddle

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur