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A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.
Book Synopsis Introduction to Cancer Biology by : Robin Hesketh
Download or read book Introduction to Cancer Biology written by Robin Hesketh and published by Cambridge University Press. This book was released on 2013 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.
Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.
Book Synopsis The Biology of Cancer by : Weinberg, Robert A.
Download or read book The Biology of Cancer written by Weinberg, Robert A. and published by W.W. Norton & Company. This book was released on 2013-05-24 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.
The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.
Book Synopsis Oxford Textbook of Cancer Biology by : Francesco Pezzella
Download or read book Oxford Textbook of Cancer Biology written by Francesco Pezzella and published by Oxford University Press. This book was released on 2019-05-02 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.
Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
Book Synopsis Molecular Biology of Cancer by : Lauren Pecorino
Download or read book Molecular Biology of Cancer written by Lauren Pecorino and published by Oxford University Press. This book was released on 2012-04-26 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
Book Synopsis Cancer Biology: How Science Works by : Carsten Carlberg
Download or read book Cancer Biology: How Science Works written by Carsten Carlberg and published by Springer Nature. This book was released on 2021-07-05 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
Principles of Cancer Biology, is an engaging book focused on providing students with a big picture view of cancer. Author Lewis Kleinsmith has written an instructional text focusing on key concepts for both students and a general audience. For those instructors who wish to delve into particular aspects of cancer biology in greater depth, each chapter contains a list of suggested readings that expand the detail as needed. The text also emphasizes the scientific evidence that underlies cancer biology, and teaches students to think critically about this evidence- as there are constantly new breakthroughs and reports in this field. For students who need the review, there are brief reviews of several topics related to DNA replication and repair, cell division, cell signaling, and inheritance patterns in chapters where these subjects are relevant. By including these reviews, the text is both accessible and engaging to a broad audience of readers who are studying cancer biology for the first time, as well as an interested general audience.
Book Synopsis Principles of Cancer Biology by : Lewis J. Kleinsmith
Download or read book Principles of Cancer Biology written by Lewis J. Kleinsmith and published by . This book was released on 2013-11-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Cancer Biology, is an engaging book focused on providing students with a big picture view of cancer. Author Lewis Kleinsmith has written an instructional text focusing on key concepts for both students and a general audience. For those instructors who wish to delve into particular aspects of cancer biology in greater depth, each chapter contains a list of suggested readings that expand the detail as needed. The text also emphasizes the scientific evidence that underlies cancer biology, and teaches students to think critically about this evidence- as there are constantly new breakthroughs and reports in this field. For students who need the review, there are brief reviews of several topics related to DNA replication and repair, cell division, cell signaling, and inheritance patterns in chapters where these subjects are relevant. By including these reviews, the text is both accessible and engaging to a broad audience of readers who are studying cancer biology for the first time, as well as an interested general audience.
The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discov
Book Synopsis Cancer Systems Biology by : Edwin Wang
Download or read book Cancer Systems Biology written by Edwin Wang and published by CRC Press. This book was released on 2010-05-04 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discov
The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models—integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencing. Offering promising insights on how to defeat cancer, the emerging field of systems biology captures the complexity of biological phenomena using mathematical and computational tools. Novel Approaches to Fighting Cancer Drawn from the authors’ decade-long work in the cancer computational systems biology laboratory at Institut Curie (Paris, France), Computational Systems Biology of Cancer explains how to apply computational systems biology approaches to cancer research. The authors provide proven techniques and tools for cancer bioinformatics and systems biology research. Effectively Use Algorithmic Methods and Bioinformatics Tools in Real Biological Applications Suitable for readers in both the computational and life sciences, this self-contained guide assumes very limited background in biology, mathematics, and computer science. It explores how computational systems biology can help fight cancer in three essential aspects: Categorising tumours Finding new targets Designing improved and tailored therapeutic strategies Each chapter introduces a problem, presents applicable concepts and state-of-the-art methods, describes existing tools, illustrates applications using real cases, lists publically available data and software, and includes references to further reading. Some chapters also contain exercises. Figures from the text and scripts/data for reproducing a breast cancer data analysis are available at www.cancer-systems-biology.net.
Book Synopsis Computational Systems Biology of Cancer by : Emmanuel Barillot
Download or read book Computational Systems Biology of Cancer written by Emmanuel Barillot and published by CRC Press. This book was released on 2012-08-25 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models—integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencing. Offering promising insights on how to defeat cancer, the emerging field of systems biology captures the complexity of biological phenomena using mathematical and computational tools. Novel Approaches to Fighting Cancer Drawn from the authors’ decade-long work in the cancer computational systems biology laboratory at Institut Curie (Paris, France), Computational Systems Biology of Cancer explains how to apply computational systems biology approaches to cancer research. The authors provide proven techniques and tools for cancer bioinformatics and systems biology research. Effectively Use Algorithmic Methods and Bioinformatics Tools in Real Biological Applications Suitable for readers in both the computational and life sciences, this self-contained guide assumes very limited background in biology, mathematics, and computer science. It explores how computational systems biology can help fight cancer in three essential aspects: Categorising tumours Finding new targets Designing improved and tailored therapeutic strategies Each chapter introduces a problem, presents applicable concepts and state-of-the-art methods, describes existing tools, illustrates applications using real cases, lists publically available data and software, and includes references to further reading. Some chapters also contain exercises. Figures from the text and scripts/data for reproducing a breast cancer data analysis are available at www.cancer-systems-biology.net.
This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease
Book Synopsis Molecular and Cell Biology of Cancer by : Rita Fior
Download or read book Molecular and Cell Biology of Cancer written by Rita Fior and published by Springer. This book was released on 2019-06-27 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease
The fourth edition of this classic text provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It defines the fundamental pathophysiologic changes that occur in tumor tissue and in the host animal or patient. Each chapter discusses the historical development of a field, citing the key experimental advances to the present day, and evaluates the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well written and well illustrated, with schematic diagrams and actual research data to demonstrate points made in the text. There is also an extensive, up-to-date bibliography, making the book valuable to scientists, and to physicians, students, and nurses interested in the field of cancer biology. The topics covered include pathologic characterization of human tumors, epidemiology of human cancer, regulation of cell proliferation and differentiation, cellular and molecular phenotypic characteristics of the cancer cell, mechanisms of carcinogenesis, tumor initiation and promotion, viral carcinogenesis, oncogenes and oncogene products, growth factors, chromosomal alterations in cancer, mechanisms of tumor metastasis, host-tumor interactions, fundamental aspects of tumor immunology, and the advances in cancer cell biology that will lead to improved diagnosis and treatment of cancer in the future.
Book Synopsis Cancer Biology by : Raymond W. Ruddon
Download or read book Cancer Biology written by Raymond W. Ruddon and published by Oxford University Press. This book was released on 2007-04-05 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of this classic text provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It defines the fundamental pathophysiologic changes that occur in tumor tissue and in the host animal or patient. Each chapter discusses the historical development of a field, citing the key experimental advances to the present day, and evaluates the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well written and well illustrated, with schematic diagrams and actual research data to demonstrate points made in the text. There is also an extensive, up-to-date bibliography, making the book valuable to scientists, and to physicians, students, and nurses interested in the field of cancer biology. The topics covered include pathologic characterization of human tumors, epidemiology of human cancer, regulation of cell proliferation and differentiation, cellular and molecular phenotypic characteristics of the cancer cell, mechanisms of carcinogenesis, tumor initiation and promotion, viral carcinogenesis, oncogenes and oncogene products, growth factors, chromosomal alterations in cancer, mechanisms of tumor metastasis, host-tumor interactions, fundamental aspects of tumor immunology, and the advances in cancer cell biology that will lead to improved diagnosis and treatment of cancer in the future.
