CellBlockistry 101

CellBlockistry 101

Author: Vinod Shidham

Publisher:

Published: 2021-05-15

Total Pages:

ISBN-13: 9781955571005

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Cancer is a lethal disease with increasing numbers. Early diagnosis with minimally invasive modality is an important step in management. Cytopathology is commonly used for early diagnosis to follow-up at various stages during the treatment of cancer.In addition to the study of cellular details in cytology preparations, the cytology specimens may have to be processed similar to the surgical biopsies for some special studies. Cell blocks of cytology specimens are comparable to the formalin fixed paraffin embedded (FFPE) tissue from surgical pathology specimens. They allow various elective ancillary studies on a variety of specimens through enhanced cytopathologic interpretation, including opportunity to perform immunohistochemistry, special stains, molecular tests, and other recently evolving studies such as proteomics. CellBlockistry is the science studying chemistry and the art of achieving quantitatively and qualitatively improved cell blocks from different types of specimens. In addition to the role of CellBlockistry in clinical medicine in the field of cancer, it has a significant role in other non-cancer areas including infection and storage disorders such amyloidis. it has an increasing role in veterinary sciences and various basic science research. This pioneering book addresses the cell block making process and "cell blocking" related challenges with recent advances in improved interdisciplinary coordination for maximally optimal outcome with ongoing research in the field.Potential readers:Pathologists, cytopathologists, cytotechnologists, cytoprep technologists, and other fields associated with cell-blocks directly or indirectly including radiologists, laboratory personnel, histotechnologists, immunohistochemistry technologists, veternary sciences, basic science researchers.


Book Synopsis CellBlockistry 101 by : Vinod Shidham

Download or read book CellBlockistry 101 written by Vinod Shidham and published by . This book was released on 2021-05-15 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a lethal disease with increasing numbers. Early diagnosis with minimally invasive modality is an important step in management. Cytopathology is commonly used for early diagnosis to follow-up at various stages during the treatment of cancer.In addition to the study of cellular details in cytology preparations, the cytology specimens may have to be processed similar to the surgical biopsies for some special studies. Cell blocks of cytology specimens are comparable to the formalin fixed paraffin embedded (FFPE) tissue from surgical pathology specimens. They allow various elective ancillary studies on a variety of specimens through enhanced cytopathologic interpretation, including opportunity to perform immunohistochemistry, special stains, molecular tests, and other recently evolving studies such as proteomics. CellBlockistry is the science studying chemistry and the art of achieving quantitatively and qualitatively improved cell blocks from different types of specimens. In addition to the role of CellBlockistry in clinical medicine in the field of cancer, it has a significant role in other non-cancer areas including infection and storage disorders such amyloidis. it has an increasing role in veterinary sciences and various basic science research. This pioneering book addresses the cell block making process and "cell blocking" related challenges with recent advances in improved interdisciplinary coordination for maximally optimal outcome with ongoing research in the field.Potential readers:Pathologists, cytopathologists, cytotechnologists, cytoprep technologists, and other fields associated with cell-blocks directly or indirectly including radiologists, laboratory personnel, histotechnologists, immunohistochemistry technologists, veternary sciences, basic science researchers.

Diagnostic Pathology: Cytopathology - E-Book

Diagnostic Pathology: Cytopathology - E-Book

Author: Dina R Mody

Publisher: Elsevier Health Sciences

Published: 2022-11-30

Total Pages: 810

ISBN-13: 0323879012

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This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cytopathology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. Covers all areas of cytopathology, including clinical, radiologic, and immunohistochemical as well as cytopathologic features and molecular correlates where applicable Contains new chapters on ancillary molecular tests specific to thyroid, prognostic/therapy-related immunomarkers in cell blocks, and small biopsies Provides new immunohistochemical and molecular coverage, including new immunostains and genomic targets Incorporates new reporting terminology (such as serous fluid and effusions) and updates to existing reporting terminologies Reflects the expanded use of fine-needle aspiration for small biopsies (FNA-B) with many more images added and updated throughout Keeps you up-to-date with current and emerging reporting systems on pancreaticobiliary, salivary, breast, and soft tissue cytology Features more than 3,000 print and online images, including carefully annotated histology and gross pathology photos, full-color illustrations, clinical photographs, and radiologic images to help practicing and in-training pathologists reach a confident diagnosis Includes new videos on such topics as the cytoprepratory process, cell transfer cell block and smears, collodion bag cell block, and more Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert cytopathology reference at the point of care


Book Synopsis Diagnostic Pathology: Cytopathology - E-Book by : Dina R Mody

Download or read book Diagnostic Pathology: Cytopathology - E-Book written by Dina R Mody and published by Elsevier Health Sciences. This book was released on 2022-11-30 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cytopathology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. Covers all areas of cytopathology, including clinical, radiologic, and immunohistochemical as well as cytopathologic features and molecular correlates where applicable Contains new chapters on ancillary molecular tests specific to thyroid, prognostic/therapy-related immunomarkers in cell blocks, and small biopsies Provides new immunohistochemical and molecular coverage, including new immunostains and genomic targets Incorporates new reporting terminology (such as serous fluid and effusions) and updates to existing reporting terminologies Reflects the expanded use of fine-needle aspiration for small biopsies (FNA-B) with many more images added and updated throughout Keeps you up-to-date with current and emerging reporting systems on pancreaticobiliary, salivary, breast, and soft tissue cytology Features more than 3,000 print and online images, including carefully annotated histology and gross pathology photos, full-color illustrations, clinical photographs, and radiologic images to help practicing and in-training pathologists reach a confident diagnosis Includes new videos on such topics as the cytoprepratory process, cell transfer cell block and smears, collodion bag cell block, and more Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert cytopathology reference at the point of care

Cytopathologic Diagnosis of Serous Fluids E-Book

Cytopathologic Diagnosis of Serous Fluids E-Book

Author: Vinod B. Shidham

Publisher: Elsevier Health Sciences

Published: 2007-09-26

Total Pages: 287

ISBN-13: 1437720862

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This new reference examines specimen processing of effusion fluids, detailing the steps needed to obtain more accurate diagnoses while avoiding common pitfalls. A methodical, algorithmic approach to the evaluation and interpretation of specimens enables you to establish a definitive diagnosis in these often difficult cases. User-friendly features - combined with extensive tables and algorithms - facilitate ease of interpretation, and highlighted information makes the most essential concepts easy to reference quickly. Avoid potential errors in diagnosis with a full chapter that offers expert approaches to specimen collection and processing. Arrive at more accurate diagnoses with the aid of step-by-step algorithms plus hundreds of illustrations - including multiple images for each phenomenon representing a broad range of stains and magnifications. Achieve optimal diagnostic certainty by viewing correlations between Pap, Diff-Quick (Romanowsky), and immunocytochemical stain for every type of serous effusion. Recognize the difference in cell samples yielded after washing the serous cavity with saline or balanced salt solution versus effusion fluid. Understand the advantages and disadvantages of Pap stains versus Diff-Quick stains in FNA evaluations. Remain up to date with the latest technologies such as liquid based cytology (SurePathTM) and ThinPrepTM. Easily apply principles to real-life practice by reviewing detailed histories. Quickly locate the guidance you need with a color-coded chapter system. Focus on the most important points with user-friendly highlighted boxes.


Book Synopsis Cytopathologic Diagnosis of Serous Fluids E-Book by : Vinod B. Shidham

Download or read book Cytopathologic Diagnosis of Serous Fluids E-Book written by Vinod B. Shidham and published by Elsevier Health Sciences. This book was released on 2007-09-26 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new reference examines specimen processing of effusion fluids, detailing the steps needed to obtain more accurate diagnoses while avoiding common pitfalls. A methodical, algorithmic approach to the evaluation and interpretation of specimens enables you to establish a definitive diagnosis in these often difficult cases. User-friendly features - combined with extensive tables and algorithms - facilitate ease of interpretation, and highlighted information makes the most essential concepts easy to reference quickly. Avoid potential errors in diagnosis with a full chapter that offers expert approaches to specimen collection and processing. Arrive at more accurate diagnoses with the aid of step-by-step algorithms plus hundreds of illustrations - including multiple images for each phenomenon representing a broad range of stains and magnifications. Achieve optimal diagnostic certainty by viewing correlations between Pap, Diff-Quick (Romanowsky), and immunocytochemical stain for every type of serous effusion. Recognize the difference in cell samples yielded after washing the serous cavity with saline or balanced salt solution versus effusion fluid. Understand the advantages and disadvantages of Pap stains versus Diff-Quick stains in FNA evaluations. Remain up to date with the latest technologies such as liquid based cytology (SurePathTM) and ThinPrepTM. Easily apply principles to real-life practice by reviewing detailed histories. Quickly locate the guidance you need with a color-coded chapter system. Focus on the most important points with user-friendly highlighted boxes.

The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology

The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology

Author: Martha Bishop Pitman

Publisher: Springer

Published: 2015-05-30

Total Pages: 107

ISBN-13: 3319165895

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This text and the terminology developed by the Papanicolaou Society of Cytopathology (P.S.C.) represents an important advance in the field of pancreaticobiliary cytopathology. This textbook/atlas is designed to present a comprehensive and state of the art approach to the cytologic diagnosis and reporting of pancreaticobiliary lesions. Chapters address each of the diagnostic categories defined by the P.S.C. The definition of each category along with the clinical pathologic entities contained within the category are discussed along with specific cytologic criteria for inclusion of a cytologic specimen within the category. Each chapter is lavishly illustrated demonstrating diagnostic criteria and examples of lesions contained within the category. Additionally, appropriate ancillary testing is discussed and where appropriate illustrated. Each chapter concludes with a discussion of appropriate management as well as estimates of malignancy risk for the category. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: Definitions, Criteria, Ancillary Testing and Management will provide the reader with a unified approach to diagnosing and reporting interpretations of cytologic specimens obtained from the pancreaticobiliary tract. This text/atlas will serve as a reference guide for pathologists, surgeons, endoscopists and radiologists.


Book Synopsis The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology by : Martha Bishop Pitman

Download or read book The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology written by Martha Bishop Pitman and published by Springer. This book was released on 2015-05-30 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text and the terminology developed by the Papanicolaou Society of Cytopathology (P.S.C.) represents an important advance in the field of pancreaticobiliary cytopathology. This textbook/atlas is designed to present a comprehensive and state of the art approach to the cytologic diagnosis and reporting of pancreaticobiliary lesions. Chapters address each of the diagnostic categories defined by the P.S.C. The definition of each category along with the clinical pathologic entities contained within the category are discussed along with specific cytologic criteria for inclusion of a cytologic specimen within the category. Each chapter is lavishly illustrated demonstrating diagnostic criteria and examples of lesions contained within the category. Additionally, appropriate ancillary testing is discussed and where appropriate illustrated. Each chapter concludes with a discussion of appropriate management as well as estimates of malignancy risk for the category. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: Definitions, Criteria, Ancillary Testing and Management will provide the reader with a unified approach to diagnosing and reporting interpretations of cytologic specimens obtained from the pancreaticobiliary tract. This text/atlas will serve as a reference guide for pathologists, surgeons, endoscopists and radiologists.

Pediatric Cytopathology

Pediatric Cytopathology

Author: Sara E. Monaco

Publisher: Springer

Published: 2017-06-27

Total Pages: 253

ISBN-13: 366253441X

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This text presents serious challenges for trainees, clinicians, and practicing pathologists and cytopathologists due to the wide spectrum of diagnoses that may be seen in children and the lack of familiarity with these entities. This reference book has been designed as a practical, high-yield review of pediatric cytopathology. Key findings are highlighted and up-to-date information is provided on the diagnosis of pediatric lesions by cytology, with extensive guidance on differential diagnosis. The book includes tables and full-color images of the cytomorphology and ancillary studies, as well as pertinent histological correlation and guidance on technical issues. Pediatric Cytopathology: A Practical Guide will be an essential reference for anyone interested in the cytomorphological findings in childhood diseases.


Book Synopsis Pediatric Cytopathology by : Sara E. Monaco

Download or read book Pediatric Cytopathology written by Sara E. Monaco and published by Springer. This book was released on 2017-06-27 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents serious challenges for trainees, clinicians, and practicing pathologists and cytopathologists due to the wide spectrum of diagnoses that may be seen in children and the lack of familiarity with these entities. This reference book has been designed as a practical, high-yield review of pediatric cytopathology. Key findings are highlighted and up-to-date information is provided on the diagnosis of pediatric lesions by cytology, with extensive guidance on differential diagnosis. The book includes tables and full-color images of the cytomorphology and ancillary studies, as well as pertinent histological correlation and guidance on technical issues. Pediatric Cytopathology: A Practical Guide will be an essential reference for anyone interested in the cytomorphological findings in childhood diseases.

The International System for Serous Fluid Cytopathology

The International System for Serous Fluid Cytopathology

Author: Ashish Chandra

Publisher: Springer Nature

Published: 2020-11-05

Total Pages: 315

ISBN-13: 3030539083

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This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How specific should a report be regarding the origin and subtyping of tumors found in serous fluids? What are the appropriate quality monitors for this specimen type? Special chapters on considerations for peritoneal washings, cytopreparatory techniques, mesothelioma and quality management are included to address these issues. The text contains literature reviews that elucidate existing evidence in support of current practices and recommendations. Expert opinions on where evidence was lacking, the most common practices were adopted by consensus, and where there was no commonality, are employed. Written by experts in the field, The International System for Serous Fluid Cytopathology serves as a collaborative effort between the International Academy of Cytology and the American Society for Cytopathology and calls upon participation of the international cytopathology and oncology communities to contribute to the development of a truly international system for reporting serous fluid cytology


Book Synopsis The International System for Serous Fluid Cytopathology by : Ashish Chandra

Download or read book The International System for Serous Fluid Cytopathology written by Ashish Chandra and published by Springer Nature. This book was released on 2020-11-05 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How specific should a report be regarding the origin and subtyping of tumors found in serous fluids? What are the appropriate quality monitors for this specimen type? Special chapters on considerations for peritoneal washings, cytopreparatory techniques, mesothelioma and quality management are included to address these issues. The text contains literature reviews that elucidate existing evidence in support of current practices and recommendations. Expert opinions on where evidence was lacking, the most common practices were adopted by consensus, and where there was no commonality, are employed. Written by experts in the field, The International System for Serous Fluid Cytopathology serves as a collaborative effort between the International Academy of Cytology and the American Society for Cytopathology and calls upon participation of the international cytopathology and oncology communities to contribute to the development of a truly international system for reporting serous fluid cytology

Diagnostic Cytopathology

Diagnostic Cytopathology

Author: Winifred Gray

Publisher:

Published: 2003

Total Pages: 1064

ISBN-13:

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Diagnostic Cytopathology provides the clinician with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and will cover the recognised normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is heavily illustrated to ensure that it will be a practical resource for daily reference in the laboratory. A uniformity of basic chapter structure will expedite the clinician's search for answers to any query. in-depth bench book that covers everyday diagnostic work. Provides the clinician with an accessible guide to diagnostic investigation and screening. Cytologic findings closely related to histology. Provides the general diagnostic pathologist in the interpretation and recognition of tissue samples. Each chapter provides a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Enables the clinician to use cytology services more effectively. Major revisions of the following chapters: Mesotheliomas, Malignant Breast Tumours, Lymph Nodes, The Pathogenesis of Cervical Neoplasia, Cervical intraepithelial neoplasia and Squamous Carcinoma of the Cervix. Brand new chapter on Automation which is increasingly important in cervical screening. Additional material on Thin Core Biopsy technique which is increasingly used in Breast Screening Program. Inclusion of new genetic markers in immunohistochemistry increasingly important in non-gynaecological areas. With 47 additional contributors.


Book Synopsis Diagnostic Cytopathology by : Winifred Gray

Download or read book Diagnostic Cytopathology written by Winifred Gray and published by . This book was released on 2003 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Cytopathology provides the clinician with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and will cover the recognised normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is heavily illustrated to ensure that it will be a practical resource for daily reference in the laboratory. A uniformity of basic chapter structure will expedite the clinician's search for answers to any query. in-depth bench book that covers everyday diagnostic work. Provides the clinician with an accessible guide to diagnostic investigation and screening. Cytologic findings closely related to histology. Provides the general diagnostic pathologist in the interpretation and recognition of tissue samples. Each chapter provides a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Enables the clinician to use cytology services more effectively. Major revisions of the following chapters: Mesotheliomas, Malignant Breast Tumours, Lymph Nodes, The Pathogenesis of Cervical Neoplasia, Cervical intraepithelial neoplasia and Squamous Carcinoma of the Cervix. Brand new chapter on Automation which is increasingly important in cervical screening. Additional material on Thin Core Biopsy technique which is increasingly used in Breast Screening Program. Inclusion of new genetic markers in immunohistochemistry increasingly important in non-gynaecological areas. With 47 additional contributors.

Collection of Diagnostic Capillary Blood Specimens

Collection of Diagnostic Capillary Blood Specimens

Author:

Publisher:

Published: 2008

Total Pages: 52

ISBN-13: 9781684400904

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Book Synopsis Collection of Diagnostic Capillary Blood Specimens by :

Download or read book Collection of Diagnostic Capillary Blood Specimens written by and published by . This book was released on 2008 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Text-Book of Psychology

A Text-Book of Psychology

Author: Edward Bradford Titchener

Publisher: Legare Street Press

Published: 2023-07-18

Total Pages: 0

ISBN-13: 9781021643407

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This classic textbook offers a comprehensive overview of the field of psychology, drawing on Titchener's vast knowledge of experimental methods and statistical analysis. The book is an essential resource for students and researchers seeking a deep understanding of the principles and practices of psychology. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.


Book Synopsis A Text-Book of Psychology by : Edward Bradford Titchener

Download or read book A Text-Book of Psychology written by Edward Bradford Titchener and published by Legare Street Press. This book was released on 2023-07-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic textbook offers a comprehensive overview of the field of psychology, drawing on Titchener's vast knowledge of experimental methods and statistical analysis. The book is an essential resource for students and researchers seeking a deep understanding of the principles and practices of psychology. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

The Papanicolaou Society of Cytopathology System for Reporting Respiratory Cytology

The Papanicolaou Society of Cytopathology System for Reporting Respiratory Cytology

Author: Lester J. Layfield

Publisher: Springer

Published: 2018-11-22

Total Pages: 151

ISBN-13: 3319972359

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This text presents comprehensive review of the recommendations of the Papanicolaou Society of Cytopathology for reporting results of respiratory cytology specimens along with advances in diagnostic, prognostic, and predictive immunohistochemical and molecular techniques which can be performed on cytology specimens.The majority of the text focuses on the standardized terminology and nomenclature for respiratory cytology as recommended by the Papanicolaou Society of Cytopathology. Each of the diagnostic categories are described in depth and formal definitions for each category are given along with cytologic criteria. Explanatory notes are given discussing limitations of the category as well as its malignancy risk and reproducibility. Management recommendations are supplied for each category. Sample reports documenting the preferred reporting format are also given. Each category is associated with a reference list establishing the evidence based nature of the categories. An in depth discussion of ancillary testing is provided, including the utilization of microbiologic culture, immunohistochemistry, and molecular techniques. Substantial emphasis is placed on molecular diagnostics necessary for optimization of personalized testing and the appropriate use of targeted therapies. The text represents a comprehensive resource for the state of the science of the cytologic diagnosis of respiratory lesions.


Book Synopsis The Papanicolaou Society of Cytopathology System for Reporting Respiratory Cytology by : Lester J. Layfield

Download or read book The Papanicolaou Society of Cytopathology System for Reporting Respiratory Cytology written by Lester J. Layfield and published by Springer. This book was released on 2018-11-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents comprehensive review of the recommendations of the Papanicolaou Society of Cytopathology for reporting results of respiratory cytology specimens along with advances in diagnostic, prognostic, and predictive immunohistochemical and molecular techniques which can be performed on cytology specimens.The majority of the text focuses on the standardized terminology and nomenclature for respiratory cytology as recommended by the Papanicolaou Society of Cytopathology. Each of the diagnostic categories are described in depth and formal definitions for each category are given along with cytologic criteria. Explanatory notes are given discussing limitations of the category as well as its malignancy risk and reproducibility. Management recommendations are supplied for each category. Sample reports documenting the preferred reporting format are also given. Each category is associated with a reference list establishing the evidence based nature of the categories. An in depth discussion of ancillary testing is provided, including the utilization of microbiologic culture, immunohistochemistry, and molecular techniques. Substantial emphasis is placed on molecular diagnostics necessary for optimization of personalized testing and the appropriate use of targeted therapies. The text represents a comprehensive resource for the state of the science of the cytologic diagnosis of respiratory lesions.