Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders

Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders

Author: M.M. Verbeek

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 359

ISBN-13: 9401710074

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Cerebral amyloid angiopathy (CAA) is a distinctive abnormality of small cerebral blood vessels, one that has intrigued neuroscientists for decades. The time seems right for a book which examines the phenomenon of CAA using a multifaceted approach: What does it produce clinically? How might CAA be imaged? What are the crucial biochemical/cellular events within cerebral vessel walls that lead to CAA? How can in vitro or transgenic experimental systems be used to understand the etiology of, or even potential treatments for, CAA? The editors have assembled key figures in the field of CAA research to examine these (and other) questions in a series of focused chapters that address specific issues of importance in understanding CAA and its clinical manifestations. Comprehending the biology and pathogenesis of this fascinating vascular lesion may even provide clues to less common forms of cerebral microvascular disease that have been recognized for decades (hypertensive microangiopathy) or more recently (CADASIL).


Book Synopsis Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders by : M.M. Verbeek

Download or read book Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders written by M.M. Verbeek and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral amyloid angiopathy (CAA) is a distinctive abnormality of small cerebral blood vessels, one that has intrigued neuroscientists for decades. The time seems right for a book which examines the phenomenon of CAA using a multifaceted approach: What does it produce clinically? How might CAA be imaged? What are the crucial biochemical/cellular events within cerebral vessel walls that lead to CAA? How can in vitro or transgenic experimental systems be used to understand the etiology of, or even potential treatments for, CAA? The editors have assembled key figures in the field of CAA research to examine these (and other) questions in a series of focused chapters that address specific issues of importance in understanding CAA and its clinical manifestations. Comprehending the biology and pathogenesis of this fascinating vascular lesion may even provide clues to less common forms of cerebral microvascular disease that have been recognized for decades (hypertensive microangiopathy) or more recently (CADASIL).


Cerebral Microbleeds

Cerebral Microbleeds

Author: David J. Werring

Publisher: Cambridge University Press

Published: 2011-05-26

Total Pages: 207

ISBN-13: 1139496212

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Stroke is a leading cause of death and disability throughout the world. About one in three symptomatic strokes are due to disease of small perforating arteries; however, most effective interventions are targeted at disease of large arteries. The underlying mechanisms and treatment of small vessel disease remain poorly understood. Microbleeds have emerged as a critical imaging marker of small vessel disease, being found in all types of stroke. With increasing evidence that microbleeds are caused by hypertensive arteriopathy and cerebral amyloid angiopathy, they are likely to play a strong future role in increasing our understanding of the causes of small vessel disease and the potential link between cerebrovascular disease and neurodegeneration. Cerebral Microbleeds summarizes our current knowledge, bringing together expert research from global authorities in the field. This authoritative and systematic text will be of interest to all clinical researchers and physicians in the fields of stroke and cognitive impairment.


Book Synopsis Cerebral Microbleeds by : David J. Werring

Download or read book Cerebral Microbleeds written by David J. Werring and published by Cambridge University Press. This book was released on 2011-05-26 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a leading cause of death and disability throughout the world. About one in three symptomatic strokes are due to disease of small perforating arteries; however, most effective interventions are targeted at disease of large arteries. The underlying mechanisms and treatment of small vessel disease remain poorly understood. Microbleeds have emerged as a critical imaging marker of small vessel disease, being found in all types of stroke. With increasing evidence that microbleeds are caused by hypertensive arteriopathy and cerebral amyloid angiopathy, they are likely to play a strong future role in increasing our understanding of the causes of small vessel disease and the potential link between cerebrovascular disease and neurodegeneration. Cerebral Microbleeds summarizes our current knowledge, bringing together expert research from global authorities in the field. This authoritative and systematic text will be of interest to all clinical researchers and physicians in the fields of stroke and cognitive impairment.


Alzheimer's Disease and Related Disorders

Alzheimer's Disease and Related Disorders

Author: Serge Gauthier

Publisher: CRC Press

Published: 2005-09-22

Total Pages: 226

ISBN-13: 0203931742

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A progress report on the cutting-edge research into Alzheimer‘s Disease and other forms of dementia, this important volume has particular emphasis on topics that are applicable to clinical practice.In this latest instalment, Serge Gauthier, Philip Scheltens and Jeffrey Cummings cover some of the emerging therapies for Alzheimer‘s Disease, including


Book Synopsis Alzheimer's Disease and Related Disorders by : Serge Gauthier

Download or read book Alzheimer's Disease and Related Disorders written by Serge Gauthier and published by CRC Press. This book was released on 2005-09-22 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: A progress report on the cutting-edge research into Alzheimer‘s Disease and other forms of dementia, this important volume has particular emphasis on topics that are applicable to clinical practice.In this latest instalment, Serge Gauthier, Philip Scheltens and Jeffrey Cummings cover some of the emerging therapies for Alzheimer‘s Disease, including


Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy

Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy

Author: Raffaella Valenti

Publisher: Firenze University Press

Published: 2018

Total Pages: 184

ISBN-13: 8864537783

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Book Synopsis Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy by : Raffaella Valenti

Download or read book Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy written by Raffaella Valenti and published by Firenze University Press. This book was released on 2018 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Oxford Textbook of Cognitive Neurology and Dementia

Oxford Textbook of Cognitive Neurology and Dementia

Author: Masud Husain

Publisher: Oxford University Press

Published: 2018-10-29

Total Pages: 513

ISBN-13: 0198831080

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This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.


Book Synopsis Oxford Textbook of Cognitive Neurology and Dementia by : Masud Husain

Download or read book Oxford Textbook of Cognitive Neurology and Dementia written by Masud Husain and published by Oxford University Press. This book was released on 2018-10-29 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.


Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition

Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-12-26

Total Pages: 55

ISBN-13: 1481613944

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Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cerebral Arterial Diseases in a concise format. The editors have built Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cerebral Arterial Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Book Synopsis Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition by :

Download or read book Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cerebral Arterial Diseases in a concise format. The editors have built Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cerebral Arterial Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cerebral Arterial Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Amyloid-beta clearance in Alzheimer’s disease

Amyloid-beta clearance in Alzheimer’s disease

Author: Robert Marr

Publisher: Frontiers Media SA

Published: 2015-03-24

Total Pages: 112

ISBN-13: 2889194434

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Strong evidence continues to accumulate indicating that amyloid-beta (Aß) is a central part of Alzheimer’s disease (AD) pathogenesis in spite of the negative evidence coming from failed clinical trials. Therefore, mechanisms of clearance of Aß are of great interest in understanding AD pathogenesis and the development of effective treatments. This topic focuses on the issues related to Aß clearance in AD. The topics covered include proteases that degrade Aß and their localization, regulation, and functions. This topic also covers issues related to clearance through uptake by glia and through low-density lipoprotein (LDL) receptor mediated mechanisms. Signal transduction related to AD pathology and clearance is also addressed. Finally, immunotherapy and other novel therapeutic approaches are discussed.


Book Synopsis Amyloid-beta clearance in Alzheimer’s disease by : Robert Marr

Download or read book Amyloid-beta clearance in Alzheimer’s disease written by Robert Marr and published by Frontiers Media SA. This book was released on 2015-03-24 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strong evidence continues to accumulate indicating that amyloid-beta (Aß) is a central part of Alzheimer’s disease (AD) pathogenesis in spite of the negative evidence coming from failed clinical trials. Therefore, mechanisms of clearance of Aß are of great interest in understanding AD pathogenesis and the development of effective treatments. This topic focuses on the issues related to Aß clearance in AD. The topics covered include proteases that degrade Aß and their localization, regulation, and functions. This topic also covers issues related to clearance through uptake by glia and through low-density lipoprotein (LDL) receptor mediated mechanisms. Signal transduction related to AD pathology and clearance is also addressed. Finally, immunotherapy and other novel therapeutic approaches are discussed.


Alzheimer's Disease and Related Disorders

Alzheimer's Disease and Related Disorders

Author:

Publisher:

Published: 1989

Total Pages: 1368

ISBN-13:

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Book Synopsis Alzheimer's Disease and Related Disorders by :

Download or read book Alzheimer's Disease and Related Disorders written by and published by . This book was released on 1989 with total page 1368 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition

Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-01-09

Total Pages: 43

ISBN-13: 1464941041

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Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cerebral Arterial Diseases in a concise format. The editors have built Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cerebral Arterial Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Book Synopsis Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition by :

Download or read book Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cerebral Arterial Diseases in a concise format. The editors have built Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cerebral Arterial Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cerebral Arterial Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Cerebrovascular Pathology in Alzheimer's Disease

Cerebrovascular Pathology in Alzheimer's Disease

Author: Jack C. De La Torre

Publisher:

Published: 1997

Total Pages: 548

ISBN-13: 9780801862144

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Do changes in the cerebrovascular system precede or follow clinical onset of Alzheimer's Disease? In this book a distinguished group of contributors addressES this question and explores the extent to which the pathological changes found in the brains of persons with Alzheimer's disease are related to cerebral blood flow, perfusion, and blood-brain barrier dysfunction. Other topics include the role of stroke, heart disease, diabetes, menopause, and blood pressure on the evolution of Alzheimer's disease; genetic factors affecting the cerebrovasculature; brain metabolic and chronic cerebral hypoperfusion; and the influence of the cerebromicrovasculature on neuronal function--all issues of critical importance in orienting research lines that may provide new answers to the Alzheimer puzzle.


Book Synopsis Cerebrovascular Pathology in Alzheimer's Disease by : Jack C. De La Torre

Download or read book Cerebrovascular Pathology in Alzheimer's Disease written by Jack C. De La Torre and published by . This book was released on 1997 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do changes in the cerebrovascular system precede or follow clinical onset of Alzheimer's Disease? In this book a distinguished group of contributors addressES this question and explores the extent to which the pathological changes found in the brains of persons with Alzheimer's disease are related to cerebral blood flow, perfusion, and blood-brain barrier dysfunction. Other topics include the role of stroke, heart disease, diabetes, menopause, and blood pressure on the evolution of Alzheimer's disease; genetic factors affecting the cerebrovasculature; brain metabolic and chronic cerebral hypoperfusion; and the influence of the cerebromicrovasculature on neuronal function--all issues of critical importance in orienting research lines that may provide new answers to the Alzheimer puzzle.