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Author: John E. Pike
Publisher:
Published: 1985
Total Pages: 444
ISBN-13: 9780881670875
DOWNLOAD EBOOKDownload or read book Chemistry of the Prostaglandins and Leukotrienes written by John E. Pike and published by . This book was released on 1985 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Prostaglandin and Thromboxane Research: Chemistry of the prostaglandins and leukotrienes written by Bengt Samuelsson and published by . This book was released on 1985 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Friedrich Marks
Publisher: John Wiley & Sons
Published: 2008-11-21
Total Pages: 408
ISBN-13: 3527613633
DOWNLOAD EBOOKPolyunsaturated fatty acids are essential for human cell metabolism. As precursors of a very large and extremely versatile family of signaling compounds they play a key role in intracellular communication. Eicosanoids constitute one of the most abundant and prominent subfamilies of these fatty acid derivatives which are formed primarily along oxidative pathways. Prostaglandins, leukotrienes, and related eicosanoids have a modulatory function in mammalian cells and are responsible for tissue responses such as inflammation or wound repair. Increasing activity in eicosanoid research sheds new light on today's most common diseases including atherosclerosis, cancer, Alzheimer's, allergies, and rheumatic diseases. The recent advances already have far-reaching implications in medicine. This detailed account, written by leading experts, covers the ground-breaking developments in recent eicosanoid research. The topics span eicosanoid biogenesis, new aspects of their pathophysiology, for example their influence on the cardiovascular system, as well as the clinical application of synthetic eicosanoids and their antagonists. Researchers and students working in biochemistry or in pharmaceutical, physiological, medicinal and neurochemistry will value this informative introduction to one of the most rapidly developing fields in cell biology.
Download or read book Prostaglandins, Leukotrienes and Other Eicosanoids written by Friedrich Marks and published by John Wiley & Sons. This book was released on 2008-11-21 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyunsaturated fatty acids are essential for human cell metabolism. As precursors of a very large and extremely versatile family of signaling compounds they play a key role in intracellular communication. Eicosanoids constitute one of the most abundant and prominent subfamilies of these fatty acid derivatives which are formed primarily along oxidative pathways. Prostaglandins, leukotrienes, and related eicosanoids have a modulatory function in mammalian cells and are responsible for tissue responses such as inflammation or wound repair. Increasing activity in eicosanoid research sheds new light on today's most common diseases including atherosclerosis, cancer, Alzheimer's, allergies, and rheumatic diseases. The recent advances already have far-reaching implications in medicine. This detailed account, written by leading experts, covers the ground-breaking developments in recent eicosanoid research. The topics span eicosanoid biogenesis, new aspects of their pathophysiology, for example their influence on the cardiovascular system, as well as the clinical application of synthetic eicosanoids and their antagonists. Researchers and students working in biochemistry or in pharmaceutical, physiological, medicinal and neurochemistry will value this informative introduction to one of the most rapidly developing fields in cell biology.
Author: Lawrence Chakrin
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 321
ISBN-13: 032315607X
DOWNLOAD EBOOKThe Leukotrienes, Chemistry and Biology discusses the significant scientific progress of leukotrienes, from the discovery of slow-reacting substance to the chemical identification of a mixture of leukotrienes. Composed of 11 chapters, the book presents an enormous increase in research on the chemistry and biology of these and related substances, especially as they relate to the etiology of allergic and inflammatory diseases. After briefly discussing the continuing perspectives on the leukotriene biology, the book describes the structure, synthesis, formation, and biological actions of leukotrienes. This is followed by a discussion on arachidonic metabolism for the development of therapeutic agents specifically designed to either inhibit the synthesis or antagonize the effects of the leukotrienes. The book also looks into the biochemical and pharmacologic control of the synthesis and actions of leukotrienes. The information is considered in the context of the specific enzymes in the pathway that may be affected by any given agent. The in vivo studies on the pulmonary mechanical effect of leukotrienes, the pharmacologic activity of leukotriene receptors, and the antagonistic property of peptidoleukotrienes as an approach to allergic disease treatment are considered in the concluding chapters of the book. This book will be of value to scientists and researchers interested in hypersensitivity reactions, inflammation, and allergic diseases.
Download or read book The Leukotrienes written by Lawrence Chakrin and published by Elsevier. This book was released on 2012-12-02 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Leukotrienes, Chemistry and Biology discusses the significant scientific progress of leukotrienes, from the discovery of slow-reacting substance to the chemical identification of a mixture of leukotrienes. Composed of 11 chapters, the book presents an enormous increase in research on the chemistry and biology of these and related substances, especially as they relate to the etiology of allergic and inflammatory diseases. After briefly discussing the continuing perspectives on the leukotriene biology, the book describes the structure, synthesis, formation, and biological actions of leukotrienes. This is followed by a discussion on arachidonic metabolism for the development of therapeutic agents specifically designed to either inhibit the synthesis or antagonize the effects of the leukotrienes. The book also looks into the biochemical and pharmacologic control of the synthesis and actions of leukotrienes. The information is considered in the context of the specific enzymes in the pathway that may be affected by any given agent. The in vivo studies on the pulmonary mechanical effect of leukotrienes, the pharmacologic activity of leukotriene receptors, and the antagonistic property of peptidoleukotrienes as an approach to allergic disease treatment are considered in the concluding chapters of the book. This book will be of value to scientists and researchers interested in hypersensitivity reactions, inflammation, and allergic diseases.
Author: John L. Ninnemann
Publisher: Cambridge University Press
Published: 1988-09-30
Total Pages: 236
ISBN-13: 0521334837
DOWNLOAD EBOOKThis study looks at the way the products of arachidonic acid metabolism are active both in normal and abnormal immune responses. While some of the fundamental issues such as whether lymphocytes are capable of producing prostaglandins and leukotrienes are still hotly debated, the evidence is overwhelming that many specific immunological problems and disease states are associated with alterations in the normal balance of arachidonic acid metabolism. This book provides a review of the history and chemistry of the arachidonic acid cascade as well as an exhaustive survey of the literature concerning the interaction of arachidonic acid metabolites with cells of the immune system. The author also presents and discusses the evidence demonstrating prostaglandin and leukotriene participation in response to injury and in malignancy, tissue and organ rejection, rheumatoid arthritis, autoimmunity and allergy.
Download or read book Prostaglandins, Leukotrienes, and the Immune Response written by John L. Ninnemann and published by Cambridge University Press. This book was released on 1988-09-30 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study looks at the way the products of arachidonic acid metabolism are active both in normal and abnormal immune responses. While some of the fundamental issues such as whether lymphocytes are capable of producing prostaglandins and leukotrienes are still hotly debated, the evidence is overwhelming that many specific immunological problems and disease states are associated with alterations in the normal balance of arachidonic acid metabolism. This book provides a review of the history and chemistry of the arachidonic acid cascade as well as an exhaustive survey of the literature concerning the interaction of arachidonic acid metabolites with cells of the immune system. The author also presents and discusses the evidence demonstrating prostaglandin and leukotriene participation in response to injury and in malignancy, tissue and organ rejection, rheumatoid arthritis, autoimmunity and allergy.
Author: P. B. Curtis-Prior
Publisher:
Published: 1988
Total Pages: 732
ISBN-13:
DOWNLOAD EBOOKThis work gathers together in a single source essays contributed by 75 authors from around the world on all aspects of prostaglandins and related eicosanoids, which are of growing importance in biomedical science.
Download or read book Prostaglandins written by P. B. Curtis-Prior and published by . This book was released on 1988 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work gathers together in a single source essays contributed by 75 authors from around the world on all aspects of prostaglandins and related eicosanoids, which are of growing importance in biomedical science.
Author: Roger F. Newton
Publisher: Butterworth-Heinemann
Published: 2016-01-21
Total Pages: 157
ISBN-13: 1483161099
DOWNLOAD EBOOKProstaglandins and Thromboxanes explores the two members of the prostanoid class of fatty acid. This book attempts to thoroughly discuss the topic after collecting enough information through research in physical and biological sciences. As the title suggests, the book revolves around prostaglandins and thromboxanes. The book's first chapter contains a discussion on the subject's history, stating the year of discovery and crediting the scientist who coined the names. The chapter ends talking about the possible uses of prostaglandins and thromboxanes in the clinic. The chapters that follow discuss the two lipids' basic and advanced synthesis, pharmacology, biosynthesis, biological activity, chemical interconversions, and metabolism, along with its subtopics. The book will serve as an excellent reference for undergraduate and graduate students in the related field.
Download or read book Prostaglandins and Thromboxanes written by Roger F. Newton and published by Butterworth-Heinemann. This book was released on 2016-01-21 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostaglandins and Thromboxanes explores the two members of the prostanoid class of fatty acid. This book attempts to thoroughly discuss the topic after collecting enough information through research in physical and biological sciences. As the title suggests, the book revolves around prostaglandins and thromboxanes. The book's first chapter contains a discussion on the subject's history, stating the year of discovery and crediting the scientist who coined the names. The chapter ends talking about the possible uses of prostaglandins and thromboxanes in the clinic. The chapters that follow discuss the two lipids' basic and advanced synthesis, pharmacology, biosynthesis, biological activity, chemical interconversions, and metabolism, along with its subtopics. The book will serve as an excellent reference for undergraduate and graduate students in the related field.
Author: S. M. M. Karim
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 239
ISBN-13: 9401196486
DOWNLOAD EBOOKThis is the second in a series of three books on advances in prostaglandin research. In recent years there has been an unparalleled interest in these compounds and as a result a vast amount of research data has accumulated since the publication of my earlier book in 1972. At that time it was possible to present a fairly comprehensive review of the various aspects of prosta glandin research in one volume. This is no longer possible and the contents are divided into three volumes; the first one dealing with prostaglandins and reproduction was published in October 1975; the present volume dealing with chemical and biochemical aspects of prostaglandin research, to be published in April 1976 and the third book dealing with physiological, pharmacological and pathological aspects of prostaglandin research wiII be published in May 1976. The authorship represents international scientists consisting of physiolo-. gists, pharmacologists, chemists, biochemists, veterinary scientists and obstetrician gynaecologists actively engaged in different areas of prosta glandin research. An attempt has been made to provide a total coverage of advances relating to prostaglandins. For the sake of completeness and continuity, material covered in the 1972 book is either briefly summarised or reference made to that edition. In recent years there have been notable advances in the chemical and biochemical aspects of prostaglandin research and these are discussed by various authorities in the chapters that follow.
Download or read book Prostaglandins: Chemical and Biochemical Aspects written by S. M. M. Karim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second in a series of three books on advances in prostaglandin research. In recent years there has been an unparalleled interest in these compounds and as a result a vast amount of research data has accumulated since the publication of my earlier book in 1972. At that time it was possible to present a fairly comprehensive review of the various aspects of prosta glandin research in one volume. This is no longer possible and the contents are divided into three volumes; the first one dealing with prostaglandins and reproduction was published in October 1975; the present volume dealing with chemical and biochemical aspects of prostaglandin research, to be published in April 1976 and the third book dealing with physiological, pharmacological and pathological aspects of prostaglandin research wiII be published in May 1976. The authorship represents international scientists consisting of physiolo-. gists, pharmacologists, chemists, biochemists, veterinary scientists and obstetrician gynaecologists actively engaged in different areas of prosta glandin research. An attempt has been made to provide a total coverage of advances relating to prostaglandins. For the sake of completeness and continuity, material covered in the 1972 book is either briefly summarised or reference made to that edition. In recent years there have been notable advances in the chemical and biochemical aspects of prostaglandin research and these are discussed by various authorities in the chapters that follow.
Author: Joshua Rokach
Publisher: Elsevier Publishing Company
Published: 1989
Total Pages: 560
ISBN-13:
DOWNLOAD EBOOKImportant advances have been made in the chemistry and biochemistry of the leukotrienes mainly as a result of the development of new biophysical and biochemical methodologies. The extraordinary effort of many scientists and the interactions of many scientific disciplines has created a vast amount of data and information and, with it, the need for a book addressing all aspects of this multidisciplinary field. This book has been written to respond to that need. It comprises six chapters which together provide a cohesive interdisciplinary coverage of the field, from the organic, analytical aspect to the biological sciences. Among the many subjects covered are many aspects of the leukotriene field which have not been covered in detail before, i.e. the numerous methodologies employed in the detection, localization and quantitation of lipoxygenase products; the role of leukotrienes in human disease states; leukotriene antagonists and lipoxygenase inhibitors, and potential therapeutic agents. The book brings together a wide variety of material to give a valuable overview of this important subject.
Download or read book Leukotrienes and Lipoxygenases written by Joshua Rokach and published by Elsevier Publishing Company. This book was released on 1989 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Important advances have been made in the chemistry and biochemistry of the leukotrienes mainly as a result of the development of new biophysical and biochemical methodologies. The extraordinary effort of many scientists and the interactions of many scientific disciplines has created a vast amount of data and information and, with it, the need for a book addressing all aspects of this multidisciplinary field. This book has been written to respond to that need. It comprises six chapters which together provide a cohesive interdisciplinary coverage of the field, from the organic, analytical aspect to the biological sciences. Among the many subjects covered are many aspects of the leukotriene field which have not been covered in detail before, i.e. the numerous methodologies employed in the detection, localization and quantitation of lipoxygenase products; the role of leukotrienes in human disease states; leukotriene antagonists and lipoxygenase inhibitors, and potential therapeutic agents. The book brings together a wide variety of material to give a valuable overview of this important subject.
Author: Peter Curtis-Prior
Publisher: John Wiley & Sons
Published: 2004-07-16
Total Pages: 654
ISBN-13: 047002061X
DOWNLOAD EBOOKThis comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).
Download or read book The Eicosanoids written by Peter Curtis-Prior and published by John Wiley & Sons. This book was released on 2004-07-16 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).
