Chromosome identification: Medicine and Natural Sciences

Chromosome identification: Medicine and Natural Sciences

Author: Torbjoern Caspersson

Publisher: Elsevier

Published: 1973-01-01

Total Pages: 357

ISBN-13: 0323162673

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Chromosome Identification—Technique and Applications in Biology and Medicine contains the proceedings of the Twenty-Third Nobel Symposium held at the Royal Swedish Academy of Sciences in Stockholm, Sweden, on September 25-27,1972. The papers review advances in chromosome banding techniques and their applications in biology and medicine. Techniques for the study of pattern constancy and for rapid karyotype analysis are discussed, along with cytological procedures; karyotypes in different organisms; somatic cell hybridization; and chemical composition of chromosomes. This book is comprised of 51 chapters divided into nine sections and begins with a survey of the cytological procedures, including fluorescence banding techniques, constitutive heterochromatin (C-band) technique, and Giemsa banding technique. The following chapters explore computerized statistical analysis of banding pattern; the use of distribution functions to describe integrated profiles of human chromosomes; the uniqueness of the human karyotype; and the application of somatic cell hybridization to the study of gene linkage and complementation. The mechanisms for certain chromosome aberration are also analyzed, together with fluorescent banding agents and differential staining of human chromosomes after oxidation treatment. This monograph will be of interest to practitioners in the fields of biology and medicine.


Book Synopsis Chromosome identification: Medicine and Natural Sciences by : Torbjoern Caspersson

Download or read book Chromosome identification: Medicine and Natural Sciences written by Torbjoern Caspersson and published by Elsevier. This book was released on 1973-01-01 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosome Identification—Technique and Applications in Biology and Medicine contains the proceedings of the Twenty-Third Nobel Symposium held at the Royal Swedish Academy of Sciences in Stockholm, Sweden, on September 25-27,1972. The papers review advances in chromosome banding techniques and their applications in biology and medicine. Techniques for the study of pattern constancy and for rapid karyotype analysis are discussed, along with cytological procedures; karyotypes in different organisms; somatic cell hybridization; and chemical composition of chromosomes. This book is comprised of 51 chapters divided into nine sections and begins with a survey of the cytological procedures, including fluorescence banding techniques, constitutive heterochromatin (C-band) technique, and Giemsa banding technique. The following chapters explore computerized statistical analysis of banding pattern; the use of distribution functions to describe integrated profiles of human chromosomes; the uniqueness of the human karyotype; and the application of somatic cell hybridization to the study of gene linkage and complementation. The mechanisms for certain chromosome aberration are also analyzed, together with fluorescent banding agents and differential staining of human chromosomes after oxidation treatment. This monograph will be of interest to practitioners in the fields of biology and medicine.

Chromosome Identification--

Chromosome Identification--

Author: Torbjörn Oskar Caspersson

Publisher:

Published: 1973

Total Pages: 0

ISBN-13:

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Book Synopsis Chromosome Identification-- by : Torbjörn Oskar Caspersson

Download or read book Chromosome Identification-- written by Torbjörn Oskar Caspersson and published by . This book was released on 1973 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment

Author: Jessica Wapner

Publisher: The Experiment, LLC

Published: 2014-04-08

Total Pages: 345

ISBN-13: 1615191658

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One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.


Book Synopsis The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment by : Jessica Wapner

Download or read book The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment written by Jessica Wapner and published by The Experiment, LLC. This book was released on 2014-04-08 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

Atlas of Human Chromosome Heteromorphisms

Atlas of Human Chromosome Heteromorphisms

Author: H.E. Wyandt

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 314

ISBN-13: 9401704333

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Critical to the accurate diagnosis of human illness is the need to distinguish clinical features that fall within the normal range from those that do not. That distinction is often challenging and not infrequently requires considerable experience at the bedside. It is not surprising that accurate cytogenetic diagnosis is also often a challenge, especially when chromosome study reveals morphologic findings that raise the question of normality. Given the realization that modern human cytogenetics is just over five decades old, it is noteworthy that thorough documentation of normal chromosome var- tion has not yet been accomplished. One key diagnostic consequence of the inability to distinguish a “normal” variation in chromosome structure from a pathologic change is a missed or inaccurate diagnosis. Clinical cytogeneticists have not, however, been idle. Rather, progressive biotechnological advances coupled with virtual completion of the human genome project have yielded increasingly better microscopic resolution of chromosome structure. Witness the progress from the early short condensed chromosomes to the later visualization of chromosomes through banding techniques, hi- resolution analysis in prophase, and more recently to analysis by fluorescent in situ hybridization (FISH).


Book Synopsis Atlas of Human Chromosome Heteromorphisms by : H.E. Wyandt

Download or read book Atlas of Human Chromosome Heteromorphisms written by H.E. Wyandt and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical to the accurate diagnosis of human illness is the need to distinguish clinical features that fall within the normal range from those that do not. That distinction is often challenging and not infrequently requires considerable experience at the bedside. It is not surprising that accurate cytogenetic diagnosis is also often a challenge, especially when chromosome study reveals morphologic findings that raise the question of normality. Given the realization that modern human cytogenetics is just over five decades old, it is noteworthy that thorough documentation of normal chromosome var- tion has not yet been accomplished. One key diagnostic consequence of the inability to distinguish a “normal” variation in chromosome structure from a pathologic change is a missed or inaccurate diagnosis. Clinical cytogeneticists have not, however, been idle. Rather, progressive biotechnological advances coupled with virtual completion of the human genome project have yielded increasingly better microscopic resolution of chromosome structure. Witness the progress from the early short condensed chromosomes to the later visualization of chromosomes through banding techniques, hi- resolution analysis in prophase, and more recently to analysis by fluorescent in situ hybridization (FISH).

Chemistry in Botanical Classification: Medicine and Natural Sciences

Chemistry in Botanical Classification: Medicine and Natural Sciences

Author: Gerd Bendz

Publisher: Elsevier

Published: 2013-10-14

Total Pages: 322

ISBN-13: 0323162517

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Medicine and Natural Sciences: Chemistry in Botanical Classification contains the proceedings of the Twenty-Fifth Nobel Symposium held in Sodergarn, Sweden, on August 20-25, 1973. The papers explore the chemical approach to plant classification and cover topics ranging from chemosystematics and applications of special classes of compounds to insects and plant chemotaxonomy. Biosynthetic pathways in chemical phylogeny and some aspects of organic geochemistry are also discussed. This book is comprised of 32 chapters divided into five sections. The first chapter provides an overview of the chemical approach to botanical classification, with special reference to the higher taxa of Magnoliophyta. The reader is then introduced to chemosystematics and the construction of phylogenetic schemes, as well as the use of a chemical character for the classification of living organisms. The following chapters focus on The chemistry of disjunct taxa; homology of biosynthetic routes; and applications of special classes of compounds such as flavonoids. The systematic distribution of ellagitannins in relation to the phylogeny and classification of the angiosperms is also considered. The final chapter describes phytochemical and biological procedures for screening of plant materials. This monograph will be of value to botanists, plant taxonomists, and chemists.


Book Synopsis Chemistry in Botanical Classification: Medicine and Natural Sciences by : Gerd Bendz

Download or read book Chemistry in Botanical Classification: Medicine and Natural Sciences written by Gerd Bendz and published by Elsevier. This book was released on 2013-10-14 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine and Natural Sciences: Chemistry in Botanical Classification contains the proceedings of the Twenty-Fifth Nobel Symposium held in Sodergarn, Sweden, on August 20-25, 1973. The papers explore the chemical approach to plant classification and cover topics ranging from chemosystematics and applications of special classes of compounds to insects and plant chemotaxonomy. Biosynthetic pathways in chemical phylogeny and some aspects of organic geochemistry are also discussed. This book is comprised of 32 chapters divided into five sections. The first chapter provides an overview of the chemical approach to botanical classification, with special reference to the higher taxa of Magnoliophyta. The reader is then introduced to chemosystematics and the construction of phylogenetic schemes, as well as the use of a chemical character for the classification of living organisms. The following chapters focus on The chemistry of disjunct taxa; homology of biosynthetic routes; and applications of special classes of compounds such as flavonoids. The systematic distribution of ellagitannins in relation to the phylogeny and classification of the angiosperms is also considered. The final chapter describes phytochemical and biological procedures for screening of plant materials. This monograph will be of value to botanists, plant taxonomists, and chemists.

Evolutionary Biology

Evolutionary Biology

Author: Max Hecht

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 470

ISBN-13: 1461569508

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The ninth volume of Evolutionary Biology represents a turning point in the history of this series. The death of Theodosius Dobzhansky was a blow to the whole field of evolutionary biology in general, and to his friends and colleagues, including the other two Editors. He played a central role in the selection of areas that were "ripe" for review papers, and his circle of friends, colleagues, and students was so wide that he could always find exactly the most appropriate author and then convince him that he should prepare the paper. Evolutionary Biology was founded in 1966 and the first volume published in 1967. Ten years-and several vicissitudes-later, it seems advisable to restate the original concept of this serial publication. The Preface of Volume 1 says, simply, We have conceived this serial as a forum in which critical reviews and com mentaries, as well as original papers and even controversial views, can be brought together to cover a broad range of interest with provocative discussion. Evolutionary Biology will provide research workers and students with an excep tional opportunity to read expert presentations of developments in areas of their field in which they are not specialists, and as specialists they will see how others assess these developments. An important feature is that contributions are not necessarily limited in length, subject, and other restrictions that usually prevail in basic research journals.


Book Synopsis Evolutionary Biology by : Max Hecht

Download or read book Evolutionary Biology written by Max Hecht and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ninth volume of Evolutionary Biology represents a turning point in the history of this series. The death of Theodosius Dobzhansky was a blow to the whole field of evolutionary biology in general, and to his friends and colleagues, including the other two Editors. He played a central role in the selection of areas that were "ripe" for review papers, and his circle of friends, colleagues, and students was so wide that he could always find exactly the most appropriate author and then convince him that he should prepare the paper. Evolutionary Biology was founded in 1966 and the first volume published in 1967. Ten years-and several vicissitudes-later, it seems advisable to restate the original concept of this serial publication. The Preface of Volume 1 says, simply, We have conceived this serial as a forum in which critical reviews and com mentaries, as well as original papers and even controversial views, can be brought together to cover a broad range of interest with provocative discussion. Evolutionary Biology will provide research workers and students with an excep tional opportunity to read expert presentations of developments in areas of their field in which they are not specialists, and as specialists they will see how others assess these developments. An important feature is that contributions are not necessarily limited in length, subject, and other restrictions that usually prevail in basic research journals.

Flow Cytogenetics

Flow Cytogenetics

Author:

Publisher: Academic Press

Published: 2012-12-02

Total Pages: 331

ISBN-13: 0080984525

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This is the first book to be devoted entirely to the application and development of flow techniques in cytogenetics. It provides comprehensive information on the use of flow cytometry and sorting for chromosome classification and purification. Cytogenetics and molecular biologists will find this book an invaluable reference source. Practical details for the preparation and analysis of chromosomes using flow cytometry Flow karyotyping for sensitive rapid analysis of chromosome normality and the detection of aberrant chromosomes Flow sorting as a source of chromosome-specific DNA for gene mapping and recombinant DNA libraries Construction and current status of chromosome-specific recombinant DNA libraries


Book Synopsis Flow Cytogenetics by :

Download or read book Flow Cytogenetics written by and published by Academic Press. This book was released on 2012-12-02 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to be devoted entirely to the application and development of flow techniques in cytogenetics. It provides comprehensive information on the use of flow cytometry and sorting for chromosome classification and purification. Cytogenetics and molecular biologists will find this book an invaluable reference source. Practical details for the preparation and analysis of chromosomes using flow cytometry Flow karyotyping for sensitive rapid analysis of chromosome normality and the detection of aberrant chromosomes Flow sorting as a source of chromosome-specific DNA for gene mapping and recombinant DNA libraries Construction and current status of chromosome-specific recombinant DNA libraries

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-07-02

Total Pages: 287

ISBN-13: 0309132975

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It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.


Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine

Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Plant Genome Diversity Volume 2

Plant Genome Diversity Volume 2

Author: Johann Greilhuber

Publisher: Springer Science & Business Media

Published: 2012-11-13

Total Pages: 360

ISBN-13: 3709111609

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This second of two volumes on Plant Genome Diversity provides, in 20 chapters, insights into the structural evolution of plant genomes with all its variations. Starting with an outline of plant phylogeny and its reconstruction, the second part of the volume describes the architecture and dynamics of the plant cell nucleus, the third examines the evolution and diversity of the karyotype in various lineages, including angiosperms, gymnosperms and monilophytes. The fourth part presents the mechanisms of polyploidization and its biological consequences and significance for land plant evolution. The fifth part deals with genome size evolution and its biological significance. Together with Volume I, this comprehensive book on the plant genome is intended for students and professionals in all fields of plant science, offering as it does a convenient entry into a burgeoning literature in a fast-moving field.


Book Synopsis Plant Genome Diversity Volume 2 by : Johann Greilhuber

Download or read book Plant Genome Diversity Volume 2 written by Johann Greilhuber and published by Springer Science & Business Media. This book was released on 2012-11-13 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second of two volumes on Plant Genome Diversity provides, in 20 chapters, insights into the structural evolution of plant genomes with all its variations. Starting with an outline of plant phylogeny and its reconstruction, the second part of the volume describes the architecture and dynamics of the plant cell nucleus, the third examines the evolution and diversity of the karyotype in various lineages, including angiosperms, gymnosperms and monilophytes. The fourth part presents the mechanisms of polyploidization and its biological consequences and significance for land plant evolution. The fifth part deals with genome size evolution and its biological significance. Together with Volume I, this comprehensive book on the plant genome is intended for students and professionals in all fields of plant science, offering as it does a convenient entry into a burgeoning literature in a fast-moving field.

Problems and Solutions for Strachan and Read's Human Molecular Genetics 2

Problems and Solutions for Strachan and Read's Human Molecular Genetics 2

Author: David James Matthes

Publisher:

Published: 2001

Total Pages: 151

ISBN-13: 9781859962022

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Book Synopsis Problems and Solutions for Strachan and Read's Human Molecular Genetics 2 by : David James Matthes

Download or read book Problems and Solutions for Strachan and Read's Human Molecular Genetics 2 written by David James Matthes and published by . This book was released on 2001 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: