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Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.
Book Synopsis Decoding Darkness by : Rudolph E Tanzi
Download or read book Decoding Darkness written by Rudolph E Tanzi and published by Basic Books. This book was released on 2008-01-07 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.
Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown. Mind Thief is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles while situating science in its historical, social, and cultural contexts. Her chronicling of the trajectory of Alzheimer’s research deftly balances rich scientific detail with attention to the wider implications. In narrating the attempts to find a treatment, Yu also offers a critical account of research and drug development and a consideration of the philosophy of aging. Wide-ranging and accessible, Mind Thief is an important book for all readers interested in the challenge of Alzheimer’s.
Book Synopsis Mind Thief by : Han Yu
Download or read book Mind Thief written by Han Yu and published by Columbia University Press. This book was released on 2021-03-02 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown. Mind Thief is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles while situating science in its historical, social, and cultural contexts. Her chronicling of the trajectory of Alzheimer’s research deftly balances rich scientific detail with attention to the wider implications. In narrating the attempts to find a treatment, Yu also offers a critical account of research and drug development and a consideration of the philosophy of aging. Wide-ranging and accessible, Mind Thief is an important book for all readers interested in the challenge of Alzheimer’s.
I've allowed myself to be kidnapped by the person I hate most in the world... I find myself in the clutches of the monster who murdered my father. He wants something from me-something I have no intention of ever giving him. But there are men with him who I fear more, men who will take whatever they want from a woman, whether or not she agrees. Locked in a dark cell, with threats coming at me from every direction, only one thing keeps me going-that the five guys who burst into my life so unapologetically will now come to rescue me. The memory of their passionate touches and kisses warm me in my darkest moments. But I'm no damsel in distress. I might need them to get me out of here, but I have plans of my own. I'll retrieve the device they've been hunting for, and I'll fight until it's back in rightful hands.
Book Synopsis Decoding Darkness by : Marissa Farrar
Download or read book Decoding Darkness written by Marissa Farrar and published by Createspace Independent Publishing Platform. This book was released on 2018-05-08 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: I've allowed myself to be kidnapped by the person I hate most in the world... I find myself in the clutches of the monster who murdered my father. He wants something from me-something I have no intention of ever giving him. But there are men with him who I fear more, men who will take whatever they want from a woman, whether or not she agrees. Locked in a dark cell, with threats coming at me from every direction, only one thing keeps me going-that the five guys who burst into my life so unapologetically will now come to rescue me. The memory of their passionate touches and kisses warm me in my darkest moments. But I'm no damsel in distress. I might need them to get me out of here, but I have plans of my own. I'll retrieve the device they've been hunting for, and I'll fight until it's back in rightful hands.
I'm the son of ruthless criminal. She is innocence incarnate. My Catalina... The girl I grew up with. I'll sacrifice everything for her. But I've been ordered to break that innocence. To take it, and corrupt it into something else. Something darker. Dirtier. To prepare her for a world she's been sheltered from all these years. She calls me her Angel. But I'm the one who just might destroy her. Get the complete trilogy of this disturbingly dark romance as one great boxed set today!
Book Synopsis For Him: The Complete Series by : Marissa Farrar
Download or read book For Him: The Complete Series written by Marissa Farrar and published by Marissa Farrar. This book was released on 2020-11-10 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: I'm the son of ruthless criminal. She is innocence incarnate. My Catalina... The girl I grew up with. I'll sacrifice everything for her. But I've been ordered to break that innocence. To take it, and corrupt it into something else. Something darker. Dirtier. To prepare her for a world she's been sheltered from all these years. She calls me her Angel. But I'm the one who just might destroy her. Get the complete trilogy of this disturbingly dark romance as one great boxed set today!
Memory loss can be one of the most terrifying aspects of a diagnosis of dementia. Yet the fear and dread of losing our memory make the experience of the disease worse than it needs to be, according to cultural critic and playwright Anne Davis Basting. She says, Forget memory. Basting emphasizes the importance of activities that focus on the present to improve the lives of persons with Alzheimer's disease and other dementias. Based on ten years of practice and research in the field, Basting’s study includes specific examples of innovative programs that stimulate growth, humor, and emotional connection; translates into accessible language a wide range of provocative academic works on memory; and addresses how advances in medical research and clinical practice are already pushing radical changes in care for persons with dementia. Bold, optimistic, and innovative, Basting's cultural critique of dementia care offers a vision for how we can change the way we think about and care for people with memory loss.
Book Synopsis Forget Memory by : Anne Davis Basting
Download or read book Forget Memory written by Anne Davis Basting and published by JHU Press. This book was released on 2009-07-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Memory loss can be one of the most terrifying aspects of a diagnosis of dementia. Yet the fear and dread of losing our memory make the experience of the disease worse than it needs to be, according to cultural critic and playwright Anne Davis Basting. She says, Forget memory. Basting emphasizes the importance of activities that focus on the present to improve the lives of persons with Alzheimer's disease and other dementias. Based on ten years of practice and research in the field, Basting’s study includes specific examples of innovative programs that stimulate growth, humor, and emotional connection; translates into accessible language a wide range of provocative academic works on memory; and addresses how advances in medical research and clinical practice are already pushing radical changes in care for persons with dementia. Bold, optimistic, and innovative, Basting's cultural critique of dementia care offers a vision for how we can change the way we think about and care for people with memory loss.
For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects, with family members watching their loved ones disappear a little more each day until the person they used to know is gone forever. It was in 1901 that German psychologist and neurologist Alois Alzheimer began working with Auguste Deter, a 51-year-old woman suffering from dementia. When several years later upon her death he examined her brain under the microscope, he remarked on two unusual features: dark blobs he called "plaques" and the twisted remnants of neurons, or "tangles." In the century since the disease was first described, there has been a great deal of scientific inquiry into its causes, but little progress in its treatment. Jay Ingram believes we are on the threshold of important new leaps in understanding, and inThe End of Memory he explains the fascinating science of plaques and tangles, recounts the imperfect history of our efforts to understand and combat the disease, and introduces us to the passionate researchers who are now working to find a cure. In the spirit of Siddhartha Mukherjee's The Emperor of All Maladies, this is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc on the lives of millions.
Book Synopsis The End of Memory by : Jay Ingram
Download or read book The End of Memory written by Jay Ingram and published by Macmillan. This book was released on 2015-09-29 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects, with family members watching their loved ones disappear a little more each day until the person they used to know is gone forever. It was in 1901 that German psychologist and neurologist Alois Alzheimer began working with Auguste Deter, a 51-year-old woman suffering from dementia. When several years later upon her death he examined her brain under the microscope, he remarked on two unusual features: dark blobs he called "plaques" and the twisted remnants of neurons, or "tangles." In the century since the disease was first described, there has been a great deal of scientific inquiry into its causes, but little progress in its treatment. Jay Ingram believes we are on the threshold of important new leaps in understanding, and inThe End of Memory he explains the fascinating science of plaques and tangles, recounts the imperfect history of our efforts to understand and combat the disease, and introduces us to the passionate researchers who are now working to find a cure. In the spirit of Siddhartha Mukherjee's The Emperor of All Maladies, this is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc on the lives of millions.
Alzheimer's disease affects four million people in the United States alone. Although it is incurable, many promising new treatments may slow the disease's progression. This scientifically based book offers support and guidance while presenting the latest treatment options.
Book Synopsis New Hope for People with Alzheimer's and Their Caregivers by : Porter Shimer
Download or read book New Hope for People with Alzheimer's and Their Caregivers written by Porter Shimer and published by Harmony. This book was released on 2002 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease affects four million people in the United States alone. Although it is incurable, many promising new treatments may slow the disease's progression. This scientifically based book offers support and guidance while presenting the latest treatment options.
This gorgeous 150th anniversary edition of Alice's Adventures in Wonderland is also a revelatory work of scholarship. Alice's Adventures in Wonderland--published 150 years ago in 1865--is a book many of us love and feel we know well. But it turns out we have only scratched the surface. Scholar David Day has spent many years down the rabbit hole of this children's classic and has emerged with a revelatory new view of its contents. What we have here, he brilliantly and persuasively argues, is a complete classical education in coded form--Carroll's gift to his "wonder child" Alice Liddell. In two continuous commentaries, woven around the complete text of the novel for ease of cross-reference on every page, David Day reveals the many layers of teaching, concealed by manipulation of language, that are carried so lightly in the beguiling form of a fairy tale. These layers relate directly to Carroll's interest in philosophy, history, mathematics, classics, poetry, spiritualism and even to his love of music--both sacred and profane. His novel is a memory palace, given to Alice as the great gift of an education. It was delivered in coded form because in that age, it was a gift no girl would be permitted to receive in any other way. Day also shows how a large number of the characters in the book are based on real Victorians. Wonderland, he shows, is a veritable "Who's Who" of Oxford at the height of its power and influence in the Victorian Age. There is so much to be found behind the imaginary characters and creatures that inhabit the pages of Alice's Adventures in Wonderland. David Day's warm, witty and brilliantly insightful guide--beautifully designed and stunningly illustrated throughout in full colour--will make you marvel at the book as never before.
Book Synopsis Alice's Adventures in Wonderland Decoded by : David Day
Download or read book Alice's Adventures in Wonderland Decoded written by David Day and published by Doubleday Canada. This book was released on 2015-09-29 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This gorgeous 150th anniversary edition of Alice's Adventures in Wonderland is also a revelatory work of scholarship. Alice's Adventures in Wonderland--published 150 years ago in 1865--is a book many of us love and feel we know well. But it turns out we have only scratched the surface. Scholar David Day has spent many years down the rabbit hole of this children's classic and has emerged with a revelatory new view of its contents. What we have here, he brilliantly and persuasively argues, is a complete classical education in coded form--Carroll's gift to his "wonder child" Alice Liddell. In two continuous commentaries, woven around the complete text of the novel for ease of cross-reference on every page, David Day reveals the many layers of teaching, concealed by manipulation of language, that are carried so lightly in the beguiling form of a fairy tale. These layers relate directly to Carroll's interest in philosophy, history, mathematics, classics, poetry, spiritualism and even to his love of music--both sacred and profane. His novel is a memory palace, given to Alice as the great gift of an education. It was delivered in coded form because in that age, it was a gift no girl would be permitted to receive in any other way. Day also shows how a large number of the characters in the book are based on real Victorians. Wonderland, he shows, is a veritable "Who's Who" of Oxford at the height of its power and influence in the Victorian Age. There is so much to be found behind the imaginary characters and creatures that inhabit the pages of Alice's Adventures in Wonderland. David Day's warm, witty and brilliantly insightful guide--beautifully designed and stunningly illustrated throughout in full colour--will make you marvel at the book as never before.
As the Shadows gather for their ultimate victory over the galaxy, Galen, the possessor of the unstoppable Spell of Destruction, leaves the stronghold of the techno-mages to lend his assistance in the final, apocalyptic battle against the evil of the Shadows.
Book Synopsis Invoking Darkness by : Jeanne Cavelos
Download or read book Invoking Darkness written by Jeanne Cavelos and published by Random House Digital, Inc.. This book was released on 2001 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the Shadows gather for their ultimate victory over the galaxy, Galen, the possessor of the unstoppable Spell of Destruction, leaves the stronghold of the techno-mages to lend his assistance in the final, apocalyptic battle against the evil of the Shadows.
A fresh and fascinating look at the philosophies, politics, and intellectual legacy of one of the twentieth century's most influential and controversial minds Occupying a pivotal position in postwar thought, Noam Chomsky is both the founder of modern linguistics and the world's most prominent political dissident. Chris Knight adopts an anthropologist's perspective on the twin output of this intellectual giant, acclaimed as much for his denunciations of US foreign policy as for his theories about language and mind. Knight explores the social and institutional context of Chomsky's thinking, showing how the tension between military funding and his role as linchpin of the political left pressured him to establish a disconnect between science on the one hand and politics on the other, deepening a split between mind and body characteristic of Western philosophy since the Enlightenment. Provocative, fearless, and engaging, this remarkable study explains the enigma of one of the greatest intellectuals of our time.
Book Synopsis Decoding Chomsky by : Chris Knight
Download or read book Decoding Chomsky written by Chris Knight and published by Yale University Press. This book was released on 2016-01-01 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fresh and fascinating look at the philosophies, politics, and intellectual legacy of one of the twentieth century's most influential and controversial minds Occupying a pivotal position in postwar thought, Noam Chomsky is both the founder of modern linguistics and the world's most prominent political dissident. Chris Knight adopts an anthropologist's perspective on the twin output of this intellectual giant, acclaimed as much for his denunciations of US foreign policy as for his theories about language and mind. Knight explores the social and institutional context of Chomsky's thinking, showing how the tension between military funding and his role as linchpin of the political left pressured him to establish a disconnect between science on the one hand and politics on the other, deepening a split between mind and body characteristic of Western philosophy since the Enlightenment. Provocative, fearless, and engaging, this remarkable study explains the enigma of one of the greatest intellectuals of our time.
