Dermal Absorption and Toxicity Assessment

Dermal Absorption and Toxicity Assessment

Author: Michael S. Roberts

Publisher: CRC Press

Published: 2007-12-14

Total Pages: 704

ISBN-13: 0849375924

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The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin ab


Book Synopsis Dermal Absorption and Toxicity Assessment by : Michael S. Roberts

Download or read book Dermal Absorption and Toxicity Assessment written by Michael S. Roberts and published by CRC Press. This book was released on 2007-12-14 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin ab

Dermal Absorption and Toxicity Assessment

Dermal Absorption and Toxicity Assessment

Author: S. Roberts Michael

Publisher: CRC Press

Published: 1998-06-23

Total Pages: 808

ISBN-13: 9780824701543

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This volume examines the dermal absoption process with emphasis on determining the toxicity arising from exposure to pharmaceuticals, cosmetics, and other substances. It serves as a bench resource for scientists seeking effective and timesaving means of estimating risk. Contributors also reveal how environmental hazards such as metal compounds, contaminated soil and water, and sun sensitivity occur and are measured through the skin. Practical information is provided on specific products, from analgesics and anti-inflammatory drugs, to perfumes, sunscreens and hair dyes.


Book Synopsis Dermal Absorption and Toxicity Assessment by : S. Roberts Michael

Download or read book Dermal Absorption and Toxicity Assessment written by S. Roberts Michael and published by CRC Press. This book was released on 1998-06-23 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines the dermal absoption process with emphasis on determining the toxicity arising from exposure to pharmaceuticals, cosmetics, and other substances. It serves as a bench resource for scientists seeking effective and timesaving means of estimating risk. Contributors also reveal how environmental hazards such as metal compounds, contaminated soil and water, and sun sensitivity occur and are measured through the skin. Practical information is provided on specific products, from analgesics and anti-inflammatory drugs, to perfumes, sunscreens and hair dyes.

Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants

Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants

Author: Rhoda G.M. Wang

Publisher: CRC Press

Published: 2017-11-22

Total Pages: 930

ISBN-13: 1351361732

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Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.


Book Synopsis Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants by : Rhoda G.M. Wang

Download or read book Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants written by Rhoda G.M. Wang and published by CRC Press. This book was released on 2017-11-22 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.

Dermal Absorption

Dermal Absorption

Author: J. Kielhorn

Publisher: World Health Organization

Published: 2006

Total Pages: 217

ISBN-13: 9241572353

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Introduction and definitions -- Skin structure and function -- Skin transport mechanisms and theoretical concepts -- Metabolism in the skin -- In vitro tests for dermal absorption -- In vivo tests for dermal absorption -- Comparative studies -- Data collections -- Estimation/prediction of dermal penetration -- Use of dermal penetration studies in risk assessment -- Controversial topics in the assessment of dermal absorption -- Conclusions and recommendations.


Book Synopsis Dermal Absorption by : J. Kielhorn

Download or read book Dermal Absorption written by J. Kielhorn and published by World Health Organization. This book was released on 2006 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and definitions -- Skin structure and function -- Skin transport mechanisms and theoretical concepts -- Metabolism in the skin -- In vitro tests for dermal absorption -- In vivo tests for dermal absorption -- Comparative studies -- Data collections -- Estimation/prediction of dermal penetration -- Use of dermal penetration studies in risk assessment -- Controversial topics in the assessment of dermal absorption -- Conclusions and recommendations.

Drugs and the Pharmaceutical Sciences V.177

Drugs and the Pharmaceutical Sciences V.177

Author: Kenneth A. Walters

Publisher:

Published: 2008

Total Pages: 678

ISBN-13:

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Book Synopsis Drugs and the Pharmaceutical Sciences V.177 by : Kenneth A. Walters

Download or read book Drugs and the Pharmaceutical Sciences V.177 written by Kenneth A. Walters and published by . This book was released on 2008 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dermal Absorption and Toxicity Assessment and Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches, 2 Volume Set

Dermal Absorption and Toxicity Assessment and Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches, 2 Volume Set

Author: Michael S. Roberts

Publisher: CRC Press

Published: 2008-04-07

Total Pages: 1248

ISBN-13: 9781420085556

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The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin absorption and the various governmental and industrial programs concerned with skin permeation and toxicity. These include alternative in silico, in vitro, and in vivo strategies to conduct studies for regulatory requirements. To make room for this new expanded content, the editors are publishing a concurrent text entitled: Dermatological and Cosmetic Development with a concentration on subjects concerned with dermatological and cosmetic therapies


Book Synopsis Dermal Absorption and Toxicity Assessment and Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches, 2 Volume Set by : Michael S. Roberts

Download or read book Dermal Absorption and Toxicity Assessment and Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches, 2 Volume Set written by Michael S. Roberts and published by CRC Press. This book was released on 2008-04-07 with total page 1248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin absorption and the various governmental and industrial programs concerned with skin permeation and toxicity. These include alternative in silico, in vitro, and in vivo strategies to conduct studies for regulatory requirements. To make room for this new expanded content, the editors are publishing a concurrent text entitled: Dermatological and Cosmetic Development with a concentration on subjects concerned with dermatological and cosmetic therapies

Principles and Practice of Skin Toxicology

Principles and Practice of Skin Toxicology

Author: Robert Chilcott

Publisher: John Wiley & Sons

Published: 2008-07-31

Total Pages: 392

ISBN-13: 0470773081

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Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.


Book Synopsis Principles and Practice of Skin Toxicology by : Robert Chilcott

Download or read book Principles and Practice of Skin Toxicology written by Robert Chilcott and published by John Wiley & Sons. This book was released on 2008-07-31 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.

Summary Report for the Workshop on Issues Associated with Dermal Exposure and Uptake

Summary Report for the Workshop on Issues Associated with Dermal Exposure and Uptake

Author:

Publisher:

Published: 2000

Total Pages: 188

ISBN-13:

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Book Synopsis Summary Report for the Workshop on Issues Associated with Dermal Exposure and Uptake by :

Download or read book Summary Report for the Workshop on Issues Associated with Dermal Exposure and Uptake written by and published by . This book was released on 2000 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method

Author: OECD

Publisher: OECD Publishing

Published: 2004-11-23

Total Pages: 8

ISBN-13: 9264071067

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The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...


Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 427: Skin Absorption: In Vivo Method written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...

Wildlife Toxicity Assessments for Chemicals of Military Concern

Wildlife Toxicity Assessments for Chemicals of Military Concern

Author: Marc Williams

Publisher: Elsevier

Published: 2015-05-21

Total Pages: 725

ISBN-13: 0128004800

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Wildlife Toxicity Assessments for Chemicals of Military Concern is a compendium of chemical-specific toxicity information with discussions on the rationale and development of Wildlife Toxicity Reference Values (TRVs) intended for use on terrestrial wildlife for risk assessment applications. Substances covered include military-related chemicals including explosives, propellants, pesticides and metals. Wildlife Toxicity Assessments for Chemicals of Military Concern is a much-needed resource designed to meet the needs of those seeking toxicological information for ecological risk assessment purposes. Each chapter targets a specific chemical and considers the current knowledge of the toxicological impacts of chemicals to terrestrial wildlife including mammalian, avian, amphibian and reptilian species. Provides detailed information on how Wildlife Toxicity Values (TRVs) for military chemicals of concern are derived and evaluated. Covers wildlife toxicity assessments of explosives, metals and environmental chemicals. Compiles relevant information on the environmental effects of chemicals on wildlife in relation to public and environmental health.


Book Synopsis Wildlife Toxicity Assessments for Chemicals of Military Concern by : Marc Williams

Download or read book Wildlife Toxicity Assessments for Chemicals of Military Concern written by Marc Williams and published by Elsevier. This book was released on 2015-05-21 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wildlife Toxicity Assessments for Chemicals of Military Concern is a compendium of chemical-specific toxicity information with discussions on the rationale and development of Wildlife Toxicity Reference Values (TRVs) intended for use on terrestrial wildlife for risk assessment applications. Substances covered include military-related chemicals including explosives, propellants, pesticides and metals. Wildlife Toxicity Assessments for Chemicals of Military Concern is a much-needed resource designed to meet the needs of those seeking toxicological information for ecological risk assessment purposes. Each chapter targets a specific chemical and considers the current knowledge of the toxicological impacts of chemicals to terrestrial wildlife including mammalian, avian, amphibian and reptilian species. Provides detailed information on how Wildlife Toxicity Values (TRVs) for military chemicals of concern are derived and evaluated. Covers wildlife toxicity assessments of explosives, metals and environmental chemicals. Compiles relevant information on the environmental effects of chemicals on wildlife in relation to public and environmental health.