Diabetic Cardiomyopathy

Diabetic Cardiomyopathy

Author: Belma Turan

Publisher: Springer Science & Business Media

Published: 2014-01-08

Total Pages: 423

ISBN-13: 146149317X

DOWNLOAD EBOOK

Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double within the next 20 years. Among the 3.8 million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy. Twenty five articles in this book are organized in three sections. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural alterations in heart. In the second section, several cellular and molecular mechanisms are discussed indicating that diabetic cardiomyopathy is a multifactorial and complex problem. The third section discusses the prevention and treatment of diabetes using appropriate diet, proper supplements including antioxidants, angiotensin inhibitors and some other drugs. All in all, this book discusses the diverse mechanisms of diabetic cardiomyopathy with some information on new therapeutic approaches for finding solutions to prevent or reverse the development of cardiac dysfunction.


Book Synopsis Diabetic Cardiomyopathy by : Belma Turan

Download or read book Diabetic Cardiomyopathy written by Belma Turan and published by Springer Science & Business Media. This book was released on 2014-01-08 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double within the next 20 years. Among the 3.8 million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy. Twenty five articles in this book are organized in three sections. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural alterations in heart. In the second section, several cellular and molecular mechanisms are discussed indicating that diabetic cardiomyopathy is a multifactorial and complex problem. The third section discusses the prevention and treatment of diabetes using appropriate diet, proper supplements including antioxidants, angiotensin inhibitors and some other drugs. All in all, this book discusses the diverse mechanisms of diabetic cardiomyopathy with some information on new therapeutic approaches for finding solutions to prevent or reverse the development of cardiac dysfunction.


Diabetic Cardiomyopathy

Diabetic Cardiomyopathy

Author: Slavica Mitrovska

Publisher:

Published: 2020-04-14

Total Pages:

ISBN-13: 9781536169577

DOWNLOAD EBOOK

Diabetic cardiomyopathy is defined as heart failure independent of the coronary artery, valve disease and hypertension. It has multifactorial aetiology but the pathogenesis is incompletely understood. Hyperglycemia, hyperlipidemia and inflammation with high oxidative stress lead to structural and functional alterations of the left ventricle (LV) and promote diabetic cardiomyopathy. Diastolic dysfunction is an early sign of diabetic cardiomyopathy. It has a long asymptomatic period, but with time leads to loss of contractile function. Hence, the identification of subclinical diabetic cardiomyopathy and correction of potentially modified risk factors are very important to delay the onset of heart failure. The aim: We aimed to assess the LV function in asymptomatic diabetic patients and its correlation with clinical and biochemical parameters. Study design: Cross-sectional study that includes a total number of 137 subjects. The target group consists of 72 asymptomatic normotensive patients with diabetes mellitus type 2, without coronary artery and valve disease. The control group is composed of 65 healthy subjects. Methods: All patients were subject to echocardiography (conventional 2D, M-mode, PW Doppler analysis and contemporary techniques-TDI and 2D-Speckle-Tracking Echocardiography). We evaluate LV diastolic and systolic function and its correlation with basic clinical characteristics (age, gender, BMI, BSA, waist to hip ratio, duration of diabetes) and biochemical analyses (glucose profile, lipid profile, CRP). The correlation between clinical, biochemical and echocardiographic parameters was assessed by the Pearson Product Moment of Correlation. A p-value of


Book Synopsis Diabetic Cardiomyopathy by : Slavica Mitrovska

Download or read book Diabetic Cardiomyopathy written by Slavica Mitrovska and published by . This book was released on 2020-04-14 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetic cardiomyopathy is defined as heart failure independent of the coronary artery, valve disease and hypertension. It has multifactorial aetiology but the pathogenesis is incompletely understood. Hyperglycemia, hyperlipidemia and inflammation with high oxidative stress lead to structural and functional alterations of the left ventricle (LV) and promote diabetic cardiomyopathy. Diastolic dysfunction is an early sign of diabetic cardiomyopathy. It has a long asymptomatic period, but with time leads to loss of contractile function. Hence, the identification of subclinical diabetic cardiomyopathy and correction of potentially modified risk factors are very important to delay the onset of heart failure. The aim: We aimed to assess the LV function in asymptomatic diabetic patients and its correlation with clinical and biochemical parameters. Study design: Cross-sectional study that includes a total number of 137 subjects. The target group consists of 72 asymptomatic normotensive patients with diabetes mellitus type 2, without coronary artery and valve disease. The control group is composed of 65 healthy subjects. Methods: All patients were subject to echocardiography (conventional 2D, M-mode, PW Doppler analysis and contemporary techniques-TDI and 2D-Speckle-Tracking Echocardiography). We evaluate LV diastolic and systolic function and its correlation with basic clinical characteristics (age, gender, BMI, BSA, waist to hip ratio, duration of diabetes) and biochemical analyses (glucose profile, lipid profile, CRP). The correlation between clinical, biochemical and echocardiographic parameters was assessed by the Pearson Product Moment of Correlation. A p-value of


Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?

Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?

Author: Maximilian Hölscher

Publisher:

Published: 2016

Total Pages:

ISBN-13:

DOWNLOAD EBOOK


Book Synopsis Diabetic Cardiomyopathy: Does the Type of Diabetes Matter? by : Maximilian Hölscher

Download or read book Diabetic Cardiomyopathy: Does the Type of Diabetes Matter? written by Maximilian Hölscher and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches

Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches

Author: Celestino Sardu

Publisher: Frontiers Media SA

Published: 2019-05-15

Total Pages: 122

ISBN-13: 2889458512

DOWNLOAD EBOOK


Book Synopsis Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches by : Celestino Sardu

Download or read book Diabetes and Heart Failure: Pathogenesis and Novel Therapeutic Approaches written by Celestino Sardu and published by Frontiers Media SA. This book was released on 2019-05-15 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The Heart in Diabetes

The Heart in Diabetes

Author: J.C. Chatham

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 281

ISBN-13: 1461312698

DOWNLOAD EBOOK

Diabetes is a major public health problem which is expected to affect 160 million people worldwide by the year 2000. Clearly an understanding of the effects of diabetes on the heart is an important step in the development of strategies to reduce the incidence of heart disease for diabetic patients, thus increasing their overall life-expectancy and quality of life. In this book, the editors bring together the different lines of evidence supportive of the idea of a diabetic cardiomyopathy. The first chapter provides an overview of the impact of cardiac dysfunction on the mortality and morbidity of the diabetic population in general, as well as a presentation of clinical aspects of heart disease in diabetes. This is followed by chapters concerned with the pathological and functional changes that occur in the heart as a result of diabetes and a description of the various therapeutic interventions that are available to reverse the effects of diabetes on the heart. Subsequent chapters focus on changes in protein synthesis, membrane function and intermediary metabolism that take place following the onset of diabetes. Since these alterations precede many of the functional and pathological changes, it may be that the processes responsible for the functional decline and tissue injury are initiated by diabetes-induced changes at the cellular and/or biochemical level.


Book Synopsis The Heart in Diabetes by : J.C. Chatham

Download or read book The Heart in Diabetes written by J.C. Chatham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a major public health problem which is expected to affect 160 million people worldwide by the year 2000. Clearly an understanding of the effects of diabetes on the heart is an important step in the development of strategies to reduce the incidence of heart disease for diabetic patients, thus increasing their overall life-expectancy and quality of life. In this book, the editors bring together the different lines of evidence supportive of the idea of a diabetic cardiomyopathy. The first chapter provides an overview of the impact of cardiac dysfunction on the mortality and morbidity of the diabetic population in general, as well as a presentation of clinical aspects of heart disease in diabetes. This is followed by chapters concerned with the pathological and functional changes that occur in the heart as a result of diabetes and a description of the various therapeutic interventions that are available to reverse the effects of diabetes on the heart. Subsequent chapters focus on changes in protein synthesis, membrane function and intermediary metabolism that take place following the onset of diabetes. Since these alterations precede many of the functional and pathological changes, it may be that the processes responsible for the functional decline and tissue injury are initiated by diabetes-induced changes at the cellular and/or biochemical level.


Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM)

Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM)

Author: VijayaKumar Sukumaran

Publisher: Frontiers Media SA

Published: 2022-08-03

Total Pages: 185

ISBN-13: 2889764974

DOWNLOAD EBOOK


Book Synopsis Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM) by : VijayaKumar Sukumaran

Download or read book Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM) written by VijayaKumar Sukumaran and published by Frontiers Media SA. This book was released on 2022-08-03 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Metabolic Cardiomyopathy

Metabolic Cardiomyopathy

Author: H. Böhles

Publisher: CRC Press

Published: 2004

Total Pages: 188

ISBN-13: 9783887631048

DOWNLOAD EBOOK

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.


Book Synopsis Metabolic Cardiomyopathy by : H. Böhles

Download or read book Metabolic Cardiomyopathy written by H. Böhles and published by CRC Press. This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.


Myocardial Metabolism

Myocardial Metabolism

Author: V. N. Smirnov

Publisher: CRC Press

Published: 1987

Total Pages: 700

ISBN-13: 9783718603114

DOWNLOAD EBOOK


Book Synopsis Myocardial Metabolism by : V. N. Smirnov

Download or read book Myocardial Metabolism written by V. N. Smirnov and published by CRC Press. This book was released on 1987 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Cardiomyopathies

Cardiomyopathies

Author: Kaan Kırali

Publisher: BoD – Books on Demand

Published: 2017-04-12

Total Pages: 472

ISBN-13: 9535130390

DOWNLOAD EBOOK

Cardiomyopathies are the most featured cardiac pathologies in the twenty-first century, that threaten public health and burden healthcare budgets. This book is composed of the main topics on pathophysiology, general forms and specific types of cardiomyopathies and it also introduces new research in the field. Specific forms with or without genetic inheritance are discussed separately to attract the readers' attention on these topics. Well-known medical follow-up strategies occur ineffective at the end-stage heart failure, however, new surgical approaches can be an alternative for these patients to get a chance at the last crossroad and to improve their life quality and survival and also to gain or prolong time until possible heart transplantation.


Book Synopsis Cardiomyopathies by : Kaan Kırali

Download or read book Cardiomyopathies written by Kaan Kırali and published by BoD – Books on Demand. This book was released on 2017-04-12 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiomyopathies are the most featured cardiac pathologies in the twenty-first century, that threaten public health and burden healthcare budgets. This book is composed of the main topics on pathophysiology, general forms and specific types of cardiomyopathies and it also introduces new research in the field. Specific forms with or without genetic inheritance are discussed separately to attract the readers' attention on these topics. Well-known medical follow-up strategies occur ineffective at the end-stage heart failure, however, new surgical approaches can be an alternative for these patients to get a chance at the last crossroad and to improve their life quality and survival and also to gain or prolong time until possible heart transplantation.


Medical Management of Diabetes and Heart Disease

Medical Management of Diabetes and Heart Disease

Author: Burton E. Sobel

Publisher: CRC Press

Published: 2002-03-06

Total Pages: 306

ISBN-13: 0824744519

DOWNLOAD EBOOK

This state-of-the-art reference details current and effective symptom-specific strategies for the diagnosis and management of diabetic patients-emphasizing the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes. Addresses the pathophysiology underlying advanced heart


Book Synopsis Medical Management of Diabetes and Heart Disease by : Burton E. Sobel

Download or read book Medical Management of Diabetes and Heart Disease written by Burton E. Sobel and published by CRC Press. This book was released on 2002-03-06 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art reference details current and effective symptom-specific strategies for the diagnosis and management of diabetic patients-emphasizing the exploration of therapeutic options available for the treatment of accelerated coronary complications associated with diabetes. Addresses the pathophysiology underlying advanced heart