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Dictyostelium

Author: Richard H. Kessin

Publisher: Cambridge University Press

Published: 2001-01-11

Total Pages: 318

ISBN-13: 0521583640

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Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.

Book Synopsis Dictyostelium by : Richard H. Kessin

Download or read book Dictyostelium written by Richard H. Kessin and published by Cambridge University Press. This book was released on 2001-01-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.

Dictyostelium discoideum Protocols

Author: Ludwig Eichinger

Publisher: Springer Science & Business Media

Published: 2008-02-02

Total Pages: 556

ISBN-13: 1597451444

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Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.

Book Synopsis Dictyostelium discoideum Protocols by : Ludwig Eichinger

Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.

Inanimate Life

Author: George M. Briggs

Publisher:

Published: 2021-07-16

Total Pages:

ISBN-13: 9781942341826

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Book Synopsis Inanimate Life by : George M. Briggs

Download or read book Inanimate Life written by George M. Briggs and published by . This book was released on 2021-07-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Development Of Dictyostelium Discoideum

Author: William Loomis

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 570

ISBN-13: 0323145663

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The Development of Dictyostelium discoideum consists of 11 chapters representing the 11 major aspects at which continuous progress are made in the study of Dictyostelium discoideum. This book begins with the discovery, classification, ecology, and development of Dictyostelium discoideum. It then outlines the advances in genetic manipulation and mutant isolation of the organism. Much of the advances in cell biology have been related to a better understanding of the composition and function of the cell membrane. Hence, analyses of Dictyostelium plasma membranes are collated. This reference material also describes the role of chemoattractants in organizing cell movements and the intracellular events triggered by occupancy of chemoreceptors. It also explains the understanding of the macromolecular components of the chemosensory system of Dictyostelium discoideum. It further discusses the cell motility, cell adhesion, morphogenetic signaling, cytodifferentiation, and gene expression in the species. Finally, the phenomenon of cell-type specification and regulation in this organism is addressed. This book will be valuable for those already familiar with the general outlines of Dictyostelium biology.

Book Synopsis The Development Of Dictyostelium Discoideum by : William Loomis

Download or read book The Development Of Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development of Dictyostelium discoideum consists of 11 chapters representing the 11 major aspects at which continuous progress are made in the study of Dictyostelium discoideum. This book begins with the discovery, classification, ecology, and development of Dictyostelium discoideum. It then outlines the advances in genetic manipulation and mutant isolation of the organism. Much of the advances in cell biology have been related to a better understanding of the composition and function of the cell membrane. Hence, analyses of Dictyostelium plasma membranes are collated. This reference material also describes the role of chemoattractants in organizing cell movements and the intracellular events triggered by occupancy of chemoreceptors. It also explains the understanding of the macromolecular components of the chemosensory system of Dictyostelium discoideum. It further discusses the cell motility, cell adhesion, morphogenetic signaling, cytodifferentiation, and gene expression in the species. Finally, the phenomenon of cell-type specification and regulation in this organism is addressed. This book will be valuable for those already familiar with the general outlines of Dictyostelium biology.

Dictyostelium Discoideum

Author: William Loomis

Publisher: Academic Press

Published: 1975

Total Pages: 224

ISBN-13:

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Dictyostelium Discoideum: A Developmental System presents D. discoideum as a model eukaryotic system to study a variety of developmental problems. The book describes the life cycle of the organism D. discoideum which exists in nature as a soil amoeba in forest detritus. The nuclei of D. discoideum contain DNA, RNA, and proteins which have properties similar to those of histones present in calf thymus nuclei. The unique sequences of the genome of the organism code for the gene products synthesize during its growth and development. One approach in genetic analyses to understanding the developmental processes of the organism is to isolate a large number of morphological mutants. The isolation process will indicate the number of variations that are open to the developing system, and will point to causal connections between stages. The text also explains that the number of cells which differentiate into stalk cells is the result of timing and mechanics of the process of culmination. Ashworth (1971) suggests that cells in pseudoplasmodia of D. discoideum adjust their positions in relation to the chemical structure of the sheath itself. A model shows how cells communicate their response to the sheath in an axial fashion. The book can prove beneficial for biochemists, micro-biologists, cellular researchers, and investigators involved in the study of cellular biology.

Book Synopsis Dictyostelium Discoideum by : William Loomis

Download or read book Dictyostelium Discoideum written by William Loomis and published by Academic Press. This book was released on 1975 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium Discoideum: A Developmental System presents D. discoideum as a model eukaryotic system to study a variety of developmental problems. The book describes the life cycle of the organism D. discoideum which exists in nature as a soil amoeba in forest detritus. The nuclei of D. discoideum contain DNA, RNA, and proteins which have properties similar to those of histones present in calf thymus nuclei. The unique sequences of the genome of the organism code for the gene products synthesize during its growth and development. One approach in genetic analyses to understanding the developmental processes of the organism is to isolate a large number of morphological mutants. The isolation process will indicate the number of variations that are open to the developing system, and will point to causal connections between stages. The text also explains that the number of cells which differentiate into stalk cells is the result of timing and mechanics of the process of culmination. Ashworth (1971) suggests that cells in pseudoplasmodia of D. discoideum adjust their positions in relation to the chemical structure of the sheath itself. A model shows how cells communicate their response to the sheath in an axial fashion. The book can prove beneficial for biochemists, micro-biologists, cellular researchers, and investigators involved in the study of cellular biology.

The Social Amoebae

Author: John Tyler Bonner

Publisher: Princeton University Press

Published: 2009-01-18

Total Pages: 164

ISBN-13: 9780691139395

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Noted biologist and author John Tyler Bonner has experimented with cellular slime molds for more than sixty years, and he has done more than anyone else to raise these peculiar collections of amoebae from a minor biological curiosity to a major model organism--one that is widely studied for clues to the development and evolution of all living things. Now, five decades after he published his first pioneering book on cellular slime molds, Bonner steps back from the proliferating and increasingly specialized knowledge about the organism to provide a broad, nontechnical picture of its whole biology, including its evolution, sociobiology, ecology, behavior, and development. The Social Amoebae draws the big lessons from decades of research, and shows how slime molds fit into and illuminate biology as a whole. Slime molds are very different from other organisms; they feed as individual amoebae before coming together to form a multicellular organism that has a remarkable ability to move and orient itself in its environment. Furthermore, these social amoebae display a sophisticated division of labor; within each organism, some cells form the stalk and others become the spores that will seed the next generation. In The Social Amoebae, Bonner examines all these parts together, giving a balanced, concise, and clear overview of slime mold biology, from molecules to cells to multicells, as he advances some unconventional and unexpected insights.

Book Synopsis The Social Amoebae by : John Tyler Bonner

Download or read book The Social Amoebae written by John Tyler Bonner and published by Princeton University Press. This book was released on 2009-01-18 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Noted biologist and author John Tyler Bonner has experimented with cellular slime molds for more than sixty years, and he has done more than anyone else to raise these peculiar collections of amoebae from a minor biological curiosity to a major model organism--one that is widely studied for clues to the development and evolution of all living things. Now, five decades after he published his first pioneering book on cellular slime molds, Bonner steps back from the proliferating and increasingly specialized knowledge about the organism to provide a broad, nontechnical picture of its whole biology, including its evolution, sociobiology, ecology, behavior, and development. The Social Amoebae draws the big lessons from decades of research, and shows how slime molds fit into and illuminate biology as a whole. Slime molds are very different from other organisms; they feed as individual amoebae before coming together to form a multicellular organism that has a remarkable ability to move and orient itself in its environment. Furthermore, these social amoebae display a sophisticated division of labor; within each organism, some cells form the stalk and others become the spores that will seed the next generation. In The Social Amoebae, Bonner examines all these parts together, giving a balanced, concise, and clear overview of slime mold biology, from molecules to cells to multicells, as he advances some unconventional and unexpected insights.

Cellular Slime Molds

Author: John Tyler Bonner

Publisher: Princeton University Press

Published: 2015-12-08

Total Pages: 224

ISBN-13: 1400876885

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Professor Bonner has rewritten more than half of this standard treatise to take account of the great amount of recent research on the cellular slime molds. He has included a larger selection of material, more figures and new plates. The bibliography has been greatly enlarged. Originally published in 1967. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Book Synopsis Cellular Slime Molds by : John Tyler Bonner

Download or read book Cellular Slime Molds written by John Tyler Bonner and published by Princeton University Press. This book was released on 2015-12-08 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Bonner has rewritten more than half of this standard treatise to take account of the great amount of recent research on the cellular slime molds. He has included a larger selection of material, more figures and new plates. The bibliography has been greatly enlarged. Originally published in 1967. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Author: Robert T. Gerlai

Publisher: Academic Press

Published: 2018-04-24

Total Pages: 710

ISBN-13: 0128041161

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Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts

Book Synopsis Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research by : Robert T. Gerlai

Download or read book Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research written by Robert T. Gerlai and published by Academic Press. This book was released on 2018-04-24 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts

The Dictyostelids

Author: Kenneth Bryan Raper

Publisher: Princeton University Press

Published: 2014-07-14

Total Pages: 467

ISBN-13: 1400856566

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Kenneth Raper tells how dictyostelids are isolated, cultivated, and conserved in the laboratory; how myxamoebae aggregate to form multicellular pseudoplasmodia; how fructifications arise by transformation of amoeboid cells into stalk cells and spores; and how similar cells can, under certain conditions, enter a sexual phase. For each known dictyostelid Professor Raper includes a complete description and photographic illustrations; one new species is described. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Book Synopsis The Dictyostelids by : Kenneth Bryan Raper

Download or read book The Dictyostelids written by Kenneth Bryan Raper and published by Princeton University Press. This book was released on 2014-07-14 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kenneth Raper tells how dictyostelids are isolated, cultivated, and conserved in the laboratory; how myxamoebae aggregate to form multicellular pseudoplasmodia; how fructifications arise by transformation of amoeboid cells into stalk cells and spores; and how similar cells can, under certain conditions, enter a sexual phase. For each known dictyostelid Professor Raper includes a complete description and photographic illustrations; one new species is described. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Dictyostelids

Author: Maria Romeralo

Publisher: Springer

Published: 2013-07-30

Total Pages: 0

ISBN-13: 9783642384868

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Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.

Book Synopsis Dictyostelids by : Maria Romeralo

Download or read book Dictyostelids written by Maria Romeralo and published by Springer. This book was released on 2013-07-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.