Platform Technologies in Drug Discovery and Validation

Platform Technologies in Drug Discovery and Validation

Author:

Publisher: Academic Press

Published: 2017-11-21

Total Pages: 690

ISBN-13: 0128130709

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Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. Unique for its treatment of platform technologies for medicinal chemistry and target validation Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field Presents state-of-the-art summaries of platform technologies


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Download or read book Platform Technologies in Drug Discovery and Validation written by and published by Academic Press. This book was released on 2017-11-21 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. Unique for its treatment of platform technologies for medicinal chemistry and target validation Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field Presents state-of-the-art summaries of platform technologies


The Law Times Reports

The Law Times Reports

Author:

Publisher:

Published: 1926

Total Pages: 804

ISBN-13:

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Download or read book The Law Times Reports written by and published by . This book was released on 1926 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Rose's Notes on the United States Supreme Court Reports

Rose's Notes on the United States Supreme Court Reports

Author: Walter Malins Rose

Publisher:

Published: 1917

Total Pages: 1296

ISBN-13:

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Book Synopsis Rose's Notes on the United States Supreme Court Reports by : Walter Malins Rose

Download or read book Rose's Notes on the United States Supreme Court Reports written by Walter Malins Rose and published by . This book was released on 1917 with total page 1296 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Reports on the Discovery of Peru

Reports on the Discovery of Peru

Author: Clements Robert Markham

Publisher:

Published: 1872

Total Pages: 178

ISBN-13:

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Book Synopsis Reports on the Discovery of Peru by : Clements Robert Markham

Download or read book Reports on the Discovery of Peru written by Clements Robert Markham and published by . This book was released on 1872 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The English Reports

The English Reports

Author:

Publisher:

Published: 1914

Total Pages: 1372

ISBN-13:

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Download or read book The English Reports written by and published by . This book was released on 1914 with total page 1372 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Annual Reprint of the Reports of the Council on Pharmacy and Chemistry of the American Medical Association

Annual Reprint of the Reports of the Council on Pharmacy and Chemistry of the American Medical Association

Author:

Publisher:

Published: 1920

Total Pages: 108

ISBN-13:

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Download or read book Annual Reprint of the Reports of the Council on Pharmacy and Chemistry of the American Medical Association written by and published by . This book was released on 1920 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The Journals of Captain James Cook on his Voyages of Discovery

The Journals of Captain James Cook on his Voyages of Discovery

Author: J.C. Beaglehole

Publisher: Routledge

Published: 2017-07-05

Total Pages: 1711

ISBN-13: 1351543245

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Captain James Cook’s first two voyages of exploration, in 1768-71 and 1772-75, had drawn the modern map of the South Pacific Ocean and had opened the door on the discovery of Antarctica. These expeditions were the subject of Volumes I and II of Dr J.C. Beaglehole’s edition of Cook’s Journals. The third voyage, on which Cook sailed in 1776, was directed to the Northern Hemisphere. Its objective was the discovery of ’a Northern Passage by sea from the Pacific to the Atlantic Ocean’ - the North-west Passage, sought since the 16th century, which would have transformed the pattern of world trade. The search was to take Cook into high latitudes where, as in the Antarctic, his skill in ice navigation was tested. Sailing north from Tahiti in 1778, Cook made the first recorded discovery of the Hawaiian Islands. On March 7 he sighted the Oregon coast in 44° N. The remarkable voyage which he made northward along the Canadian and Alaskan coasts and through Bering Strait to his farthest north in 70° nearly disproved the existence of a navigable passage towards the Atlantic and produced charts of impressive accuracy. Returning to Hawaii to refit, Cook met his death in a clash with the natives as tragic as it seems unnecessary. Dr Beaglehole discusses, with sympathy and insight, the tensions which led Cook, by then a tired man, into miscalculations alien to his own nature and habits. The volume and vitality of the records, both textual and graphic, for this voyage surpass those even for Cook’s second voyage. The surgeons William Anderson and David Samwell, both admirable observers, left journals which are also here printed in full for the first time. The documentation is completed, as in the previous volumes, by appendixes of documents and correspondence and by reproductions of original drawings and paintings mainly by John Webber, the artist of the expedition. In Dr Beaglehole’s words, ’no one can study attentively the records of Cook’s third, and last, v


Book Synopsis The Journals of Captain James Cook on his Voyages of Discovery by : J.C. Beaglehole

Download or read book The Journals of Captain James Cook on his Voyages of Discovery written by J.C. Beaglehole and published by Routledge. This book was released on 2017-07-05 with total page 1711 pages. Available in PDF, EPUB and Kindle. Book excerpt: Captain James Cook’s first two voyages of exploration, in 1768-71 and 1772-75, had drawn the modern map of the South Pacific Ocean and had opened the door on the discovery of Antarctica. These expeditions were the subject of Volumes I and II of Dr J.C. Beaglehole’s edition of Cook’s Journals. The third voyage, on which Cook sailed in 1776, was directed to the Northern Hemisphere. Its objective was the discovery of ’a Northern Passage by sea from the Pacific to the Atlantic Ocean’ - the North-west Passage, sought since the 16th century, which would have transformed the pattern of world trade. The search was to take Cook into high latitudes where, as in the Antarctic, his skill in ice navigation was tested. Sailing north from Tahiti in 1778, Cook made the first recorded discovery of the Hawaiian Islands. On March 7 he sighted the Oregon coast in 44° N. The remarkable voyage which he made northward along the Canadian and Alaskan coasts and through Bering Strait to his farthest north in 70° nearly disproved the existence of a navigable passage towards the Atlantic and produced charts of impressive accuracy. Returning to Hawaii to refit, Cook met his death in a clash with the natives as tragic as it seems unnecessary. Dr Beaglehole discusses, with sympathy and insight, the tensions which led Cook, by then a tired man, into miscalculations alien to his own nature and habits. The volume and vitality of the records, both textual and graphic, for this voyage surpass those even for Cook’s second voyage. The surgeons William Anderson and David Samwell, both admirable observers, left journals which are also here printed in full for the first time. The documentation is completed, as in the previous volumes, by appendixes of documents and correspondence and by reproductions of original drawings and paintings mainly by John Webber, the artist of the expedition. In Dr Beaglehole’s words, ’no one can study attentively the records of Cook’s third, and last, v


The Discovery of the Baltic

The Discovery of the Baltic

Author: Nils Blomkvist

Publisher: BRILL

Published: 2004-11-01

Total Pages: 784

ISBN-13: 9047406443

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Nils Blomkvist discusses how the Baltic Rim was initially Europeanized between 1075 and 1225 AD. He compares the indigenous civilisations to the prevailing western European one. After the expansive Viking period, European penetration became a process of discovery. The importance of the Catholic Reform movement and its unintentional ties to the formation of an endurable commodity market are outlined. Clashes and compromises are investigated in case studies of the Kalmarsund region, Gotland and the Daugava valley. Dissimilar cases of state formation are compared: those of Sweden and Livonia. Many classical scholarly problems are revisited. A new approach to the period's narrative sources brings to life Scandinavian, German, Russian, Finno-Ugrian and Baltic attitudes and day-to-day concern in the midst of a change of epic dimensions.


Book Synopsis The Discovery of the Baltic by : Nils Blomkvist

Download or read book The Discovery of the Baltic written by Nils Blomkvist and published by BRILL. This book was released on 2004-11-01 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nils Blomkvist discusses how the Baltic Rim was initially Europeanized between 1075 and 1225 AD. He compares the indigenous civilisations to the prevailing western European one. After the expansive Viking period, European penetration became a process of discovery. The importance of the Catholic Reform movement and its unintentional ties to the formation of an endurable commodity market are outlined. Clashes and compromises are investigated in case studies of the Kalmarsund region, Gotland and the Daugava valley. Dissimilar cases of state formation are compared: those of Sweden and Livonia. Many classical scholarly problems are revisited. A new approach to the period's narrative sources brings to life Scandinavian, German, Russian, Finno-Ugrian and Baltic attitudes and day-to-day concern in the midst of a change of epic dimensions.


Index-Based Discovery Services

Index-Based Discovery Services

Author: Marshall Breeding

Publisher: ALA TechSource

Published: 2018-11-01

Total Pages: 33

ISBN-13: 9780838916179

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This report shares data describing the use of the following discovery services among colleges and universities in the United States: WorldCat Discovery Service and its predecessor WorldCat Local from OCLC, Summon and Primo from Ex Libris, and EBSCO Discovery Service from EBSCO Information Services.


Book Synopsis Index-Based Discovery Services by : Marshall Breeding

Download or read book Index-Based Discovery Services written by Marshall Breeding and published by ALA TechSource. This book was released on 2018-11-01 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report shares data describing the use of the following discovery services among colleges and universities in the United States: WorldCat Discovery Service and its predecessor WorldCat Local from OCLC, Summon and Primo from Ex Libris, and EBSCO Discovery Service from EBSCO Information Services.


Reports of Cases Argued and Determined in the English Courts of Common Law

Reports of Cases Argued and Determined in the English Courts of Common Law

Author: Great Britain. Courts

Publisher:

Published: 1873

Total Pages: 550

ISBN-13:

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Book Synopsis Reports of Cases Argued and Determined in the English Courts of Common Law by : Great Britain. Courts

Download or read book Reports of Cases Argued and Determined in the English Courts of Common Law written by Great Britain. Courts and published by . This book was released on 1873 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: