Diseases at the Wildlife - Livestock Interface

Diseases at the Wildlife - Livestock Interface

Author: Joaquín Vicente

Publisher: Springer Nature

Published: 2021-04-29

Total Pages: 425

ISBN-13: 303065365X

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Shared diseases among wildlife, livestock and humans, often transboundary, are relevant to public health and global economy, as being highlighted currently relative to the global COVID19 pandemic. Diseases at these interfaces also impact the conservation of biodiversity and must be considered when managing wildlife. While wildlife and domestic livestock have coexisted in dynamic systems for thousands of years, spillover disease risks are higher today than in the past due to global patterns of increasing close contact and interactions among wildlife, livestock and humans in the context of complex, diverse and numerous circumstances. Multidisciplinary studies of animal interfaces, especially those involving wildlife, therefore, must be brought to the forefront so that knowledge gaps can be realized and filled to inform managers and policy makers. In the first part of the book authors illustrate and discuss ecological and epidemiological concepts related to the interfaces, with a vision towards socio-ecological system health. In addition, the history of past animal interfaces provides the necessary perspective to focus current questions, better understand present situations, and informs how we can best approach the future. The second part discusses the myriad of similar and differing wildlife- livestock interfaces found around the world from a regional point of view. The third part focuses on how to assess the spatial and temporal overlap between livestock and wildlife, and authors present new technical innovations about how inter-transmissions between wild and domestic populations can be quantified. An overview of main modeling approaches available to quantify multi-host disease transmission at the wildlife/livestock interface, illustrated with specific-case studies, is also presented. Finally, the need for interdisciplinary approaches and a dedicated thematic field to approach the wildlife/livestock interfaces and create opportunities to promote wildlife–livestock coexistence is emphasized. The concluding chapter presents perspectives and directions to better understanding disease dynamics at the wildlife/livestock interface, global change and implications for the future. The changing distribution of interfaces, ongoing human and environmental changes (e. g. climate warming, changes in animal production systems, etc.) and their likely impacts and consequences for the interfaces and disease transmission processes are all discussed.


Book Synopsis Diseases at the Wildlife - Livestock Interface by : Joaquín Vicente

Download or read book Diseases at the Wildlife - Livestock Interface written by Joaquín Vicente and published by Springer Nature. This book was released on 2021-04-29 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shared diseases among wildlife, livestock and humans, often transboundary, are relevant to public health and global economy, as being highlighted currently relative to the global COVID19 pandemic. Diseases at these interfaces also impact the conservation of biodiversity and must be considered when managing wildlife. While wildlife and domestic livestock have coexisted in dynamic systems for thousands of years, spillover disease risks are higher today than in the past due to global patterns of increasing close contact and interactions among wildlife, livestock and humans in the context of complex, diverse and numerous circumstances. Multidisciplinary studies of animal interfaces, especially those involving wildlife, therefore, must be brought to the forefront so that knowledge gaps can be realized and filled to inform managers and policy makers. In the first part of the book authors illustrate and discuss ecological and epidemiological concepts related to the interfaces, with a vision towards socio-ecological system health. In addition, the history of past animal interfaces provides the necessary perspective to focus current questions, better understand present situations, and informs how we can best approach the future. The second part discusses the myriad of similar and differing wildlife- livestock interfaces found around the world from a regional point of view. The third part focuses on how to assess the spatial and temporal overlap between livestock and wildlife, and authors present new technical innovations about how inter-transmissions between wild and domestic populations can be quantified. An overview of main modeling approaches available to quantify multi-host disease transmission at the wildlife/livestock interface, illustrated with specific-case studies, is also presented. Finally, the need for interdisciplinary approaches and a dedicated thematic field to approach the wildlife/livestock interfaces and create opportunities to promote wildlife–livestock coexistence is emphasized. The concluding chapter presents perspectives and directions to better understanding disease dynamics at the wildlife/livestock interface, global change and implications for the future. The changing distribution of interfaces, ongoing human and environmental changes (e. g. climate warming, changes in animal production systems, etc.) and their likely impacts and consequences for the interfaces and disease transmission processes are all discussed.


One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases

One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases

Author: John S. Mackenzie

Publisher: Springer Science & Business Media

Published: 2013-11-22

Total Pages: 238

ISBN-13: 3642358462

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One Health is an emerging concept that aims to bring together human, animal, and environmental health. Achieving harmonized approaches for disease detection and prevention is difficult because traditional boundaries of medical and veterinary practice must be crossed. In the 19th and early 20th centuries this was not the case—then researchers like Louis Pasteur and Robert Koch and physicians like William Osler and Rudolph Virchow crossed the boundaries between animal and human health. More recently Calvin Schwabe revised the concept of One Medicine. This was critical for the advancement of the field of epidemiology, especially as applied to zoonotic diseases. The future of One Health is at a crossroads with a need to more clearly define its boundaries and demonstrate its benefits. Interestingly the greatest acceptance of One Health is seen in the developing world where it is having significant impacts on control of infectious diseases.


Book Synopsis One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases by : John S. Mackenzie

Download or read book One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases written by John S. Mackenzie and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: One Health is an emerging concept that aims to bring together human, animal, and environmental health. Achieving harmonized approaches for disease detection and prevention is difficult because traditional boundaries of medical and veterinary practice must be crossed. In the 19th and early 20th centuries this was not the case—then researchers like Louis Pasteur and Robert Koch and physicians like William Osler and Rudolph Virchow crossed the boundaries between animal and human health. More recently Calvin Schwabe revised the concept of One Medicine. This was critical for the advancement of the field of epidemiology, especially as applied to zoonotic diseases. The future of One Health is at a crossroads with a need to more clearly define its boundaries and demonstrate its benefits. Interestingly the greatest acceptance of One Health is seen in the developing world where it is having significant impacts on control of infectious diseases.


Management of Disease in Wild Mammals

Management of Disease in Wild Mammals

Author: Richard Delahay

Publisher: Springer Science & Business Media

Published: 2008-12-11

Total Pages: 291

ISBN-13: 4431771344

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In recent years nobody could have failed to notice the frequent and often sensati- alist media headlines warning of the latest global disease threat to humankind. But behind all the hyperbole lie real challenges related to dealing with the increasing incidence of emerging zoonotic disease events, the majority of which are thought to originate in wildlife (Jones et al. 2008). There are also many important diseases of domestic livestock which also occur in wildlife (e. g. foot and mouth disease and classical swine fever in wild boar, bovine tuberculosis in deer, badgers or possums), some of which can have a devastating impact on the farming industry, the wider rural economy and ultimately the public purse. But we should also not forget that wildlife diseases may have serious implications for the conservation of biodiversity. For some of the rarest, most endangered species (such as the Ethiopian wolf) d- ease may pose the greatest threat to their survival. If we are to avoid or reduce these impacts then we must improve our ability to detect and manage the risks associated with disease in wildlife populations. This is a challenge that will require expertise from many different disciplines: veterinary, ecological, medical, economic, poli- cal and zoological. In such an interdisciplinary field it is difficult to stay up to date with contemporary ideas and with techniques that may be rapidly evolving.


Book Synopsis Management of Disease in Wild Mammals by : Richard Delahay

Download or read book Management of Disease in Wild Mammals written by Richard Delahay and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years nobody could have failed to notice the frequent and often sensati- alist media headlines warning of the latest global disease threat to humankind. But behind all the hyperbole lie real challenges related to dealing with the increasing incidence of emerging zoonotic disease events, the majority of which are thought to originate in wildlife (Jones et al. 2008). There are also many important diseases of domestic livestock which also occur in wildlife (e. g. foot and mouth disease and classical swine fever in wild boar, bovine tuberculosis in deer, badgers or possums), some of which can have a devastating impact on the farming industry, the wider rural economy and ultimately the public purse. But we should also not forget that wildlife diseases may have serious implications for the conservation of biodiversity. For some of the rarest, most endangered species (such as the Ethiopian wolf) d- ease may pose the greatest threat to their survival. If we are to avoid or reduce these impacts then we must improve our ability to detect and manage the risks associated with disease in wildlife populations. This is a challenge that will require expertise from many different disciplines: veterinary, ecological, medical, economic, poli- cal and zoological. In such an interdisciplinary field it is difficult to stay up to date with contemporary ideas and with techniques that may be rapidly evolving.


Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross-Species Transmission

Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross-Species Transmission

Author: James E. Childs

Publisher: Springer

Published: 2010-11-30

Total Pages: 0

ISBN-13: 9783642089961

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This volume offers an overview of the processes of zoonotic viral emergence, the intricacies of host/virus interactions, and the role of biological transitions and modifying factors. The themes introduced here are amplified and explored in detail by the contributing authors, who explore the mechanisms and unique circumstances by which evolution, biology, history, and current context have contrived to drive the emergence of different zoonotic agents by a series of related events.


Book Synopsis Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross-Species Transmission by : James E. Childs

Download or read book Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross-Species Transmission written by James E. Childs and published by Springer. This book was released on 2010-11-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers an overview of the processes of zoonotic viral emergence, the intricacies of host/virus interactions, and the role of biological transitions and modifying factors. The themes introduced here are amplified and explored in detail by the contributing authors, who explore the mechanisms and unique circumstances by which evolution, biology, history, and current context have contrived to drive the emergence of different zoonotic agents by a series of related events.


Animal Health at the Crossroads

Animal Health at the Crossroads

Author: National Research Council

Publisher: National Academies Press

Published: 2005-12-17

Total Pages: 287

ISBN-13: 0309092590

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The confirmed case of "mad cow" disease (BSE) in June 2005 illustrates the economic impact of disease outbreaks, as additional countries closed their markets to U.S. beef and beef products. Emerging diseases also threaten public health-11 out of 12 of the major global disease outbreaks over the last decade were from zoonotic agents (that spread from animals to humans). Animal Health at the Crossroads: Preventing, Detecting, and Diagnosing Animal Diseases finds that, in general, the U.S. animal health framework has been slow to take advantage of state-of-the-art technologies being used now to protect public health; better diagnostic tests for identifying all animal diseases should be made a priority. The report also recommends that the nation establish a high-level, authoritative, and accountable coordinating mechanism to engage and enhance partnerships among local, state, and federal agencies, and the private sector.


Book Synopsis Animal Health at the Crossroads by : National Research Council

Download or read book Animal Health at the Crossroads written by National Research Council and published by National Academies Press. This book was released on 2005-12-17 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The confirmed case of "mad cow" disease (BSE) in June 2005 illustrates the economic impact of disease outbreaks, as additional countries closed their markets to U.S. beef and beef products. Emerging diseases also threaten public health-11 out of 12 of the major global disease outbreaks over the last decade were from zoonotic agents (that spread from animals to humans). Animal Health at the Crossroads: Preventing, Detecting, and Diagnosing Animal Diseases finds that, in general, the U.S. animal health framework has been slow to take advantage of state-of-the-art technologies being used now to protect public health; better diagnostic tests for identifying all animal diseases should be made a priority. The report also recommends that the nation establish a high-level, authoritative, and accountable coordinating mechanism to engage and enhance partnerships among local, state, and federal agencies, and the private sector.


Improving Food Safety Through a One Health Approach

Improving Food Safety Through a One Health Approach

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-09-10

Total Pages: 418

ISBN-13: 0309259363

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Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.


Book Synopsis Improving Food Safety Through a One Health Approach by : Institute of Medicine

Download or read book Improving Food Safety Through a One Health Approach written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-10 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.


Investigation and Management of Disease in Wild Animals

Investigation and Management of Disease in Wild Animals

Author: G.A. Wobeser

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 257

ISBN-13: 1475756097

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- A hypothesis is a proposition, set forth as an explanation for the occurrence of a phenomenon, that can be tested. - The basis for scientific investigation is the collection of information to formulate and test hypotheses. - Experimental methods measure the effect of manipulations caused by the investigator; observational methods collect information about naturally occurring events. - There are three sub-types of experimental techniques that differ in the way subjects are chosen for inclusion in the study, in the amount of control that the investigator has over variables, and in the method used to assess changes in other variables. - Descriptive observational studies dominate the early phase of most investigations and involve the description of disease-related events in the population. Associations among factors may be observed but the strength of the associations is not measured. - Analytical observation al techniques are of three basic types: prevalence surveys, case:control studies, and incidence or cohort studies. All attempt to explain the nature of relationships among various factors and to measure the strength of associations. - Prevalence surveys and case:control studies deal with disease existing at the time of the study; incidence studies are concerned with the development of disease over time. - Observational studies may be retrospective, using existing data, or prospective with collection of new information.


Book Synopsis Investigation and Management of Disease in Wild Animals by : G.A. Wobeser

Download or read book Investigation and Management of Disease in Wild Animals written by G.A. Wobeser and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: - A hypothesis is a proposition, set forth as an explanation for the occurrence of a phenomenon, that can be tested. - The basis for scientific investigation is the collection of information to formulate and test hypotheses. - Experimental methods measure the effect of manipulations caused by the investigator; observational methods collect information about naturally occurring events. - There are three sub-types of experimental techniques that differ in the way subjects are chosen for inclusion in the study, in the amount of control that the investigator has over variables, and in the method used to assess changes in other variables. - Descriptive observational studies dominate the early phase of most investigations and involve the description of disease-related events in the population. Associations among factors may be observed but the strength of the associations is not measured. - Analytical observation al techniques are of three basic types: prevalence surveys, case:control studies, and incidence or cohort studies. All attempt to explain the nature of relationships among various factors and to measure the strength of associations. - Prevalence surveys and case:control studies deal with disease existing at the time of the study; incidence studies are concerned with the development of disease over time. - Observational studies may be retrospective, using existing data, or prospective with collection of new information.


World Livestock 2013

World Livestock 2013

Author: Food and Agriculture Organization of the United Nations

Publisher: Food & Agriculture Org.

Published: 2018-08-22

Total Pages: 130

ISBN-13: 9251079277

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The World Livestock 2013: Changing disease landscapes looks at the evidence of changing disease dynamics involving livestock and explores three key areas: the Pressure, including drivers and risk factors that contribute to disease emergence, spread and persistence; the State, describing the disease dynamics that result from the Pressure and their subsequent impact; and the Response, required both to adapt and improve the State and to mitigate the Pressure. The report argues that a comprehensive approach for the promotion of global health is needed to face the complexities of the changing disease landscapes, giving greater emphasis on agro-ecological resilience, protection of biodiversity and efficient use of natural resources to ensure safer food supply chains, particularly in areas worst afflicted by poverty and animal diseases. Speeding up response times by early detection and reaction – including improved policies that address disease drivers – is key. Forging a safer, healthier world requires engagement in the One Health approach, which involves all relevant actors and disciplines spanning animal, human and environmental health sectors.


Book Synopsis World Livestock 2013 by : Food and Agriculture Organization of the United Nations

Download or read book World Livestock 2013 written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2018-08-22 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Livestock 2013: Changing disease landscapes looks at the evidence of changing disease dynamics involving livestock and explores three key areas: the Pressure, including drivers and risk factors that contribute to disease emergence, spread and persistence; the State, describing the disease dynamics that result from the Pressure and their subsequent impact; and the Response, required both to adapt and improve the State and to mitigate the Pressure. The report argues that a comprehensive approach for the promotion of global health is needed to face the complexities of the changing disease landscapes, giving greater emphasis on agro-ecological resilience, protection of biodiversity and efficient use of natural resources to ensure safer food supply chains, particularly in areas worst afflicted by poverty and animal diseases. Speeding up response times by early detection and reaction – including improved policies that address disease drivers – is key. Forging a safer, healthier world requires engagement in the One Health approach, which involves all relevant actors and disciplines spanning animal, human and environmental health sectors.


Achieving Sustainable Global Capacity for Surveillance and Response to Emerging Diseases of Zoonotic Origin

Achieving Sustainable Global Capacity for Surveillance and Response to Emerging Diseases of Zoonotic Origin

Author: National Research Council

Publisher: National Academies Press

Published: 2009-01-22

Total Pages: 152

ISBN-13: 0309128188

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One of the biggest threats today is the uncertainty surrounding the emergence of a novel pathogen or the re-emergence of a known infectious disease that might result in disease outbreaks with great losses of human life and immense global economic consequences. Over the past six decades, most of the emerging infectious disease events in humans have been caused by zoonotic pathogens-those infectious agents that are transmitted from animals to humans. In June 2008, the Institute of Medicine's and National Research Council's Committee on Achieving Sustainable Global Capacity for Surveillance and Response to Emerging Diseases of Zoonotic Origin convened a workshop. This workshop addressed the reasons for the transmission of zoonotic disease and explored the current global capacity for zoonotic disease surveillance.


Book Synopsis Achieving Sustainable Global Capacity for Surveillance and Response to Emerging Diseases of Zoonotic Origin by : National Research Council

Download or read book Achieving Sustainable Global Capacity for Surveillance and Response to Emerging Diseases of Zoonotic Origin written by National Research Council and published by National Academies Press. This book was released on 2009-01-22 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the biggest threats today is the uncertainty surrounding the emergence of a novel pathogen or the re-emergence of a known infectious disease that might result in disease outbreaks with great losses of human life and immense global economic consequences. Over the past six decades, most of the emerging infectious disease events in humans have been caused by zoonotic pathogens-those infectious agents that are transmitted from animals to humans. In June 2008, the Institute of Medicine's and National Research Council's Committee on Achieving Sustainable Global Capacity for Surveillance and Response to Emerging Diseases of Zoonotic Origin convened a workshop. This workshop addressed the reasons for the transmission of zoonotic disease and explored the current global capacity for zoonotic disease surveillance.


Workforce Needs in Veterinary Medicine

Workforce Needs in Veterinary Medicine

Author: National Research Council

Publisher: National Academies Press

Published: 2013-11-17

Total Pages: 322

ISBN-13: 0309257441

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The U.S. veterinary medical profession contributes to society in diverse ways, from developing drugs and protecting the food supply to treating companion animals and investigating animal diseases in the wild. In a study of the issues related to the veterinary medical workforce, including demographics, workforce supply, trends affecting job availability, and capacity of the educational system to fill future demands, a National Research Council committee found that the profession faces important challenges in maintaining the economic sustainability of veterinary practice and education, building its scholarly foundations, and evolving veterinary service to meet changing societal needs. Many concerns about the profession came into focus following the outbreak of West Nile fever in 1999, and the subsequent outbreaks of SARS, monkeypox, bovine spongiform encephalopathy, highly pathogenic avian influenza, H1N1 influenza, and a variety of food safety and environmental issues heightened public concerns. They also raised further questions about the directions of veterinary medicine and the capacity of public health service the profession provides both in the United States and abroad. To address some of the problems facing the veterinary profession, greater public and private support for education and research in veterinary medicine is needed. The public, policymakers, and even medical professionals are frequently unaware of how veterinary medicine fundamentally supports both animal and human health and well-being. This report seeks to broaden the public's understanding and attempts to anticipate some of the needs and measures that are essential for the profession to fulfill given its changing roles in the 21st century.


Book Synopsis Workforce Needs in Veterinary Medicine by : National Research Council

Download or read book Workforce Needs in Veterinary Medicine written by National Research Council and published by National Academies Press. This book was released on 2013-11-17 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. veterinary medical profession contributes to society in diverse ways, from developing drugs and protecting the food supply to treating companion animals and investigating animal diseases in the wild. In a study of the issues related to the veterinary medical workforce, including demographics, workforce supply, trends affecting job availability, and capacity of the educational system to fill future demands, a National Research Council committee found that the profession faces important challenges in maintaining the economic sustainability of veterinary practice and education, building its scholarly foundations, and evolving veterinary service to meet changing societal needs. Many concerns about the profession came into focus following the outbreak of West Nile fever in 1999, and the subsequent outbreaks of SARS, monkeypox, bovine spongiform encephalopathy, highly pathogenic avian influenza, H1N1 influenza, and a variety of food safety and environmental issues heightened public concerns. They also raised further questions about the directions of veterinary medicine and the capacity of public health service the profession provides both in the United States and abroad. To address some of the problems facing the veterinary profession, greater public and private support for education and research in veterinary medicine is needed. The public, policymakers, and even medical professionals are frequently unaware of how veterinary medicine fundamentally supports both animal and human health and well-being. This report seeks to broaden the public's understanding and attempts to anticipate some of the needs and measures that are essential for the profession to fulfill given its changing roles in the 21st century.