Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer

Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer

Author: Che-Pei Kung

Publisher: Frontiers Media SA

Published: 2019-09-23

Total Pages: 130

ISBN-13: 2889630307

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Metabolic diseases and cancers account for half of all mortalities in the world, underscoring the significance of understanding the etiology of these diseases and developing effective therapies. Genomic research in the 21st century has brought cancer and metabolic disease, two once seemingly parallel ailments, as close to each other as they’ve ever been. Many genetic factors have been found to display functions regulating both cancer and metabolic disease. In this research topic: "Double-edged Swords: Genetic Factors That Influence The Pathogenesis of Both MetabolicDisease and Cancer", you will be introduced to individual genes, as well as genetic pathways that play important roles in influencing the progression of both metabolic disease and cancer. By no means covering an exhaustive list of genes qualified, this collection of articles rather serves as a precursor of what is yet to come in biomedical research. It paints the big picture of one of the major fields contributing to the future of “precision medicine”.


Book Synopsis Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer by : Che-Pei Kung

Download or read book Double-edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer written by Che-Pei Kung and published by Frontiers Media SA. This book was released on 2019-09-23 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic diseases and cancers account for half of all mortalities in the world, underscoring the significance of understanding the etiology of these diseases and developing effective therapies. Genomic research in the 21st century has brought cancer and metabolic disease, two once seemingly parallel ailments, as close to each other as they’ve ever been. Many genetic factors have been found to display functions regulating both cancer and metabolic disease. In this research topic: "Double-edged Swords: Genetic Factors That Influence The Pathogenesis of Both MetabolicDisease and Cancer", you will be introduced to individual genes, as well as genetic pathways that play important roles in influencing the progression of both metabolic disease and cancer. By no means covering an exhaustive list of genes qualified, this collection of articles rather serves as a precursor of what is yet to come in biomedical research. It paints the big picture of one of the major fields contributing to the future of “precision medicine”.


The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism

Author: Anne Le

Publisher: Springer

Published: 2018-06-26

Total Pages: 186

ISBN-13: 331977736X

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Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.


Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.


Double-edged swords: Important factors connecting metabolic disorders and cancer development - from basic research to translational applications

Double-edged swords: Important factors connecting metabolic disorders and cancer development - from basic research to translational applications

Author: Che-Pei Kung

Publisher: Frontiers Media SA

Published: 2023-04-04

Total Pages: 139

ISBN-13: 2832519393

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Book Synopsis Double-edged swords: Important factors connecting metabolic disorders and cancer development - from basic research to translational applications by : Che-Pei Kung

Download or read book Double-edged swords: Important factors connecting metabolic disorders and cancer development - from basic research to translational applications written by Che-Pei Kung and published by Frontiers Media SA. This book was released on 2023-04-04 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Signal Transduction in Cancer

Signal Transduction in Cancer

Author: David A. Frank

Publisher: Springer Science & Business Media

Published: 2002-12-31

Total Pages: 358

ISBN-13: 1402073402

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One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."


Book Synopsis Signal Transduction in Cancer by : David A. Frank

Download or read book Signal Transduction in Cancer written by David A. Frank and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."


Cancer Therapy: The Challenge of Handling a Double-Edged Sword

Cancer Therapy: The Challenge of Handling a Double-Edged Sword

Author: Raquel Abalo

Publisher: Frontiers Media SA

Published: 2022-10-18

Total Pages: 345

ISBN-13: 2889766446

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Book Synopsis Cancer Therapy: The Challenge of Handling a Double-Edged Sword by : Raquel Abalo

Download or read book Cancer Therapy: The Challenge of Handling a Double-Edged Sword written by Raquel Abalo and published by Frontiers Media SA. This book was released on 2022-10-18 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Nutrition in the Prevention and Treatment of Disease

Nutrition in the Prevention and Treatment of Disease

Author: Ann M. Coulston

Publisher: Academic Press

Published: 2013

Total Pages: 921

ISBN-13: 0123918847

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This comprehensive clinical nutrition textbook uniquely focuses on the clinical applications and disease prevention of nutrition, clearly linking the contributions of basic science to applied nutrition research and, in turn, to research-based patient care guidelines.


Book Synopsis Nutrition in the Prevention and Treatment of Disease by : Ann M. Coulston

Download or read book Nutrition in the Prevention and Treatment of Disease written by Ann M. Coulston and published by Academic Press. This book was released on 2013 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive clinical nutrition textbook uniquely focuses on the clinical applications and disease prevention of nutrition, clearly linking the contributions of basic science to applied nutrition research and, in turn, to research-based patient care guidelines.


Inflammation and Cancer

Inflammation and Cancer

Author: Bharat B. Aggarwal

Publisher: Springer

Published: 2014-05-12

Total Pages: 489

ISBN-13: 3034808372

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This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.


Book Synopsis Inflammation and Cancer by : Bharat B. Aggarwal

Download or read book Inflammation and Cancer written by Bharat B. Aggarwal and published by Springer. This book was released on 2014-05-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.


The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment

The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment

Author: Hiromi Wada

Publisher: Frontiers Media SA

Published: 2023-07-21

Total Pages: 164

ISBN-13: 2832526934

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Book Synopsis The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment by : Hiromi Wada

Download or read book The impact of alkalizing the acidic tumor microenvironment to improve efficacy of cancer treatment written by Hiromi Wada and published by Frontiers Media SA. This book was released on 2023-07-21 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Stress Response Signaling in Tumor Development and its Implications for Cancer Treatment

Stress Response Signaling in Tumor Development and its Implications for Cancer Treatment

Author: Shuyu Zhang

Publisher: Frontiers Media SA

Published: 2022-10-13

Total Pages: 364

ISBN-13: 2832502318

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Book Synopsis Stress Response Signaling in Tumor Development and its Implications for Cancer Treatment by : Shuyu Zhang

Download or read book Stress Response Signaling in Tumor Development and its Implications for Cancer Treatment written by Shuyu Zhang and published by Frontiers Media SA. This book was released on 2022-10-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Ovarian Cancer

Ovarian Cancer

Author: Omer Devaja

Publisher: BoD – Books on Demand

Published: 2018-10-24

Total Pages: 366

ISBN-13: 1789843332

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Ovarian cancer management is a rapidly changing field with new treatment agents available as a result of a greater understanding of the pathogenesis of this disease. In addition, both surgical and chemotherapeutic treatment strategies are evolving to maximise response in this disease. This book brings together leading specialists from around the world to discuss and outline a variety of new concepts in ovarian cancer, ranging from molecular biology and genetics through screening to both surgical and chemotherapeutic management.


Book Synopsis Ovarian Cancer by : Omer Devaja

Download or read book Ovarian Cancer written by Omer Devaja and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ovarian cancer management is a rapidly changing field with new treatment agents available as a result of a greater understanding of the pathogenesis of this disease. In addition, both surgical and chemotherapeutic treatment strategies are evolving to maximise response in this disease. This book brings together leading specialists from around the world to discuss and outline a variety of new concepts in ovarian cancer, ranging from molecular biology and genetics through screening to both surgical and chemotherapeutic management.