Emerging molecular mechanisms and therapeutics of autoimmune liver or kidney diseases

Emerging molecular mechanisms and therapeutics of autoimmune liver or kidney diseases

Author: Jiabo Wang

Publisher: Frontiers Media SA

Published: 2024-03-27

Total Pages: 130

ISBN-13: 2832547001

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Book Synopsis Emerging molecular mechanisms and therapeutics of autoimmune liver or kidney diseases by : Jiabo Wang

Download or read book Emerging molecular mechanisms and therapeutics of autoimmune liver or kidney diseases written by Jiabo Wang and published by Frontiers Media SA. This book was released on 2024-03-27 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Drug-Induced Liver Injury

Drug-Induced Liver Injury

Author:

Publisher: Academic Press

Published: 2019-07-13

Total Pages: 288

ISBN-13: 0128173173

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Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series


Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series


Defects in Regulation: How, Where and When The Immune System Can Go Wrong

Defects in Regulation: How, Where and When The Immune System Can Go Wrong

Author: Ger Rijkers

Publisher: Frontiers Media SA

Published: 2022-02-03

Total Pages: 117

ISBN-13: 2889714462

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Book Synopsis Defects in Regulation: How, Where and When The Immune System Can Go Wrong by : Ger Rijkers

Download or read book Defects in Regulation: How, Where and When The Immune System Can Go Wrong written by Ger Rijkers and published by Frontiers Media SA. This book was released on 2022-02-03 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Biomarkers in Liver Disease

Biomarkers in Liver Disease

Author: Victor R. Preedy

Publisher: Springer

Published: 2017-07-14

Total Pages: 0

ISBN-13: 9789400776746

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In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.


Book Synopsis Biomarkers in Liver Disease by : Victor R. Preedy

Download or read book Biomarkers in Liver Disease written by Victor R. Preedy and published by Springer. This book was released on 2017-07-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.


Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment

Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment

Author: Zhangqun Ye

Publisher: Frontiers Media SA

Published: 2023-12-29

Total Pages: 156

ISBN-13: 283254181X

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It is well known that the immune microenvironment is critical to the progression of genitourinary malignancies and benign diseases. A variety of cellular and molecular properties of the immune microenvironment may influence disease outcome by altering the balance of suppressive versus inflammatory or cytotoxic responses. Emerging evidence suggests that immunoediting is a key factor of phenotypic change, immunological alterations caused by physical activity or drug treatments could promote antitumor or anti-inflammatory activity. Conversely, microenvironment deficits or dysregulation can instigate or worsen pathological progression, thereby contributing to urinary disease development and progression. Thus, understanding how immune microenvironments react and maintain appropriate antitumor or anti-inflammatory responses is important for identifying actionable therapies to improve genitourinary health. Recent technological developments, particularly in the areas of genetic modification and redox indicators, provide hopeful new treatments not only in urinary cancer, kidney cancer, bladder cancer, relatively rare adrenocortical cancer, and penile cancer but also in begin diseases like kidney stones and kidney injuries. The purpose of this topic is to provide up-to-date reviews and original articles that highlight research on immunological mediators of tumor progression and inflammatory-related genitourinary diseases, which we hope will not only integrate our current understanding but crystallize nascent questions that will help move the field forward. This research topic aims to inspire novel insights into the immunity mechanisms, novel therapeutic targets, and effective combinational strategies of urinary immunotherapies.


Book Synopsis Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment by : Zhangqun Ye

Download or read book Emerging Molecular Signaling Pathways and Therapeutic Targets in the Genitourinary Immune Microenvironment written by Zhangqun Ye and published by Frontiers Media SA. This book was released on 2023-12-29 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well known that the immune microenvironment is critical to the progression of genitourinary malignancies and benign diseases. A variety of cellular and molecular properties of the immune microenvironment may influence disease outcome by altering the balance of suppressive versus inflammatory or cytotoxic responses. Emerging evidence suggests that immunoediting is a key factor of phenotypic change, immunological alterations caused by physical activity or drug treatments could promote antitumor or anti-inflammatory activity. Conversely, microenvironment deficits or dysregulation can instigate or worsen pathological progression, thereby contributing to urinary disease development and progression. Thus, understanding how immune microenvironments react and maintain appropriate antitumor or anti-inflammatory responses is important for identifying actionable therapies to improve genitourinary health. Recent technological developments, particularly in the areas of genetic modification and redox indicators, provide hopeful new treatments not only in urinary cancer, kidney cancer, bladder cancer, relatively rare adrenocortical cancer, and penile cancer but also in begin diseases like kidney stones and kidney injuries. The purpose of this topic is to provide up-to-date reviews and original articles that highlight research on immunological mediators of tumor progression and inflammatory-related genitourinary diseases, which we hope will not only integrate our current understanding but crystallize nascent questions that will help move the field forward. This research topic aims to inspire novel insights into the immunity mechanisms, novel therapeutic targets, and effective combinational strategies of urinary immunotherapies.


Advances in Pathogenesis, Etiology, and Therapies for Ankylosing Spondylitis

Advances in Pathogenesis, Etiology, and Therapies for Ankylosing Spondylitis

Author: Jieruo Gu

Publisher: Frontiers Media SA

Published: 2022-02-10

Total Pages: 106

ISBN-13: 2889743209

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Book Synopsis Advances in Pathogenesis, Etiology, and Therapies for Ankylosing Spondylitis by : Jieruo Gu

Download or read book Advances in Pathogenesis, Etiology, and Therapies for Ankylosing Spondylitis written by Jieruo Gu and published by Frontiers Media SA. This book was released on 2022-02-10 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Immune-Related Non-Communicable Diseases in Africa

Immune-Related Non-Communicable Diseases in Africa

Author: Mohamed-Ridha Barbouche

Publisher: Frontiers Media SA

Published: 2022-02-17

Total Pages: 116

ISBN-13: 2889744191

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Book Synopsis Immune-Related Non-Communicable Diseases in Africa by : Mohamed-Ridha Barbouche

Download or read book Immune-Related Non-Communicable Diseases in Africa written by Mohamed-Ridha Barbouche and published by Frontiers Media SA. This book was released on 2022-02-17 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Emerging Talents in Frontiers in Pharmacology: Gastrointestinal and Hepatic Pharmacology 2022

Emerging Talents in Frontiers in Pharmacology: Gastrointestinal and Hepatic Pharmacology 2022

Author: Laura Grasa

Publisher: Frontiers Media SA

Published: 2022-11-25

Total Pages: 135

ISBN-13: 2832507077

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Book Synopsis Emerging Talents in Frontiers in Pharmacology: Gastrointestinal and Hepatic Pharmacology 2022 by : Laura Grasa

Download or read book Emerging Talents in Frontiers in Pharmacology: Gastrointestinal and Hepatic Pharmacology 2022 written by Laura Grasa and published by Frontiers Media SA. This book was released on 2022-11-25 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis

Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis

Author: Cecilia Battistelli

Publisher: Frontiers Media SA

Published: 2020-02-10

Total Pages: 219

ISBN-13: 2889635023

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Book Synopsis Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis by : Cecilia Battistelli

Download or read book Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis written by Cecilia Battistelli and published by Frontiers Media SA. This book was released on 2020-02-10 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Hepatotoxicity

Hepatotoxicity

Author: Hyman J. Zimmerman

Publisher: Lippincott Williams & Wilkins

Published: 1999

Total Pages: 848

ISBN-13: 9780781719520

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Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.


Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.