Evolutionary Computation in Gene Regulatory Network Research

Evolutionary Computation in Gene Regulatory Network Research

Author: Hitoshi Iba

Publisher: John Wiley & Sons

Published: 2016-01-21

Total Pages: 464

ISBN-13: 1119079780

DOWNLOAD EBOOK

Introducing a handbook for gene regulatory network research using evolutionary computation, with applications for computer scientists, computational and system biologists This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics. • Provides a reference for current and future research in gene regulatory networks (GRN) using evolutionary computation (EC) • Covers sub-domains of GRN research using EC, such as expression profile analysis, reverse engineering, GRN evolution, applications • Contains useful contents for courses in gene regulatory networks, systems biology, computational biology, and synthetic biology • Delivers state-of-the-art research in genetic algorithms, genetic programming, and swarm intelligence Evolutionary Computation in Gene Regulatory Network Research is a reference for researchers and professionals in computer science, systems biology, and bioinformatics, as well as upper undergraduate, graduate, and postgraduate students. Hitoshi Iba is a Professor in the Department of Information and Communication Engineering, Graduate School of Information Science and Technology, at the University of Tokyo, Toyko, Japan. He is an Associate Editor of the IEEE Transactions on Evolutionary Computation and the journal of Genetic Programming and Evolvable Machines. Nasimul Noman is a lecturer in the School of Electrical Engineering and Computer Science at the University of Newcastle, NSW, Australia. From 2002 to 2012 he was a faculty member at the University of Dhaka, Bangladesh. Noman is an Editor of the BioMed Research International journal. His research interests include computational biology, synthetic biology, and bioinformatics.


Book Synopsis Evolutionary Computation in Gene Regulatory Network Research by : Hitoshi Iba

Download or read book Evolutionary Computation in Gene Regulatory Network Research written by Hitoshi Iba and published by John Wiley & Sons. This book was released on 2016-01-21 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing a handbook for gene regulatory network research using evolutionary computation, with applications for computer scientists, computational and system biologists This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics. • Provides a reference for current and future research in gene regulatory networks (GRN) using evolutionary computation (EC) • Covers sub-domains of GRN research using EC, such as expression profile analysis, reverse engineering, GRN evolution, applications • Contains useful contents for courses in gene regulatory networks, systems biology, computational biology, and synthetic biology • Delivers state-of-the-art research in genetic algorithms, genetic programming, and swarm intelligence Evolutionary Computation in Gene Regulatory Network Research is a reference for researchers and professionals in computer science, systems biology, and bioinformatics, as well as upper undergraduate, graduate, and postgraduate students. Hitoshi Iba is a Professor in the Department of Information and Communication Engineering, Graduate School of Information Science and Technology, at the University of Tokyo, Toyko, Japan. He is an Associate Editor of the IEEE Transactions on Evolutionary Computation and the journal of Genetic Programming and Evolvable Machines. Nasimul Noman is a lecturer in the School of Electrical Engineering and Computer Science at the University of Newcastle, NSW, Australia. From 2002 to 2012 he was a faculty member at the University of Dhaka, Bangladesh. Noman is an Editor of the BioMed Research International journal. His research interests include computational biology, synthetic biology, and bioinformatics.

Evolutionary Computation in Gene Regulatory Network Research

Evolutionary Computation in Gene Regulatory Network Research

Author: Andy Goodwin

Publisher: Createspace Independent Publishing Platform

Published: 2017-05-23

Total Pages: 428

ISBN-13: 9781975978105

DOWNLOAD EBOOK

This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics.


Book Synopsis Evolutionary Computation in Gene Regulatory Network Research by : Andy Goodwin

Download or read book Evolutionary Computation in Gene Regulatory Network Research written by Andy Goodwin and published by Createspace Independent Publishing Platform. This book was released on 2017-05-23 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics.

Evolutionary Approach to Machine Learning and Deep Neural Networks

Evolutionary Approach to Machine Learning and Deep Neural Networks

Author: Hitoshi Iba

Publisher: Springer

Published: 2018-06-15

Total Pages: 245

ISBN-13: 9811302006

DOWNLOAD EBOOK

This book provides theoretical and practical knowledge about a methodology for evolutionary algorithm-based search strategy with the integration of several machine learning and deep learning techniques. These include convolutional neural networks, Gröbner bases, relevance vector machines, transfer learning, bagging and boosting methods, clustering techniques (affinity propagation), and belief networks, among others. The development of such tools contributes to better optimizing methodologies. Beginning with the essentials of evolutionary algorithms and covering interdisciplinary research topics, the contents of this book are valuable for different classes of readers: novice, intermediate, and also expert readers from related fields. Following the chapters on introduction and basic methods, Chapter 3 details a new research direction, i.e., neuro-evolution, an evolutionary method for the generation of deep neural networks, and also describes how evolutionary methods are extended in combination with machine learning techniques. Chapter 4 includes novel methods such as particle swarm optimization based on affinity propagation (PSOAP), and transfer learning for differential evolution (TRADE), another machine learning approach for extending differential evolution. The last chapter is dedicated to the state of the art in gene regulatory network (GRN) research as one of the most interesting and active research fields. The author describes an evolving reaction network, which expands the neuro-evolution methodology to produce a type of genetic network suitable for biochemical systems and has succeeded in designing genetic circuits in synthetic biology. The author also presents real-world GRN application to several artificial intelligent tasks, proposing a framework of motion generation by GRNs (MONGERN), which evolves GRNs to operate a real humanoid robot.


Book Synopsis Evolutionary Approach to Machine Learning and Deep Neural Networks by : Hitoshi Iba

Download or read book Evolutionary Approach to Machine Learning and Deep Neural Networks written by Hitoshi Iba and published by Springer. This book was released on 2018-06-15 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides theoretical and practical knowledge about a methodology for evolutionary algorithm-based search strategy with the integration of several machine learning and deep learning techniques. These include convolutional neural networks, Gröbner bases, relevance vector machines, transfer learning, bagging and boosting methods, clustering techniques (affinity propagation), and belief networks, among others. The development of such tools contributes to better optimizing methodologies. Beginning with the essentials of evolutionary algorithms and covering interdisciplinary research topics, the contents of this book are valuable for different classes of readers: novice, intermediate, and also expert readers from related fields. Following the chapters on introduction and basic methods, Chapter 3 details a new research direction, i.e., neuro-evolution, an evolutionary method for the generation of deep neural networks, and also describes how evolutionary methods are extended in combination with machine learning techniques. Chapter 4 includes novel methods such as particle swarm optimization based on affinity propagation (PSOAP), and transfer learning for differential evolution (TRADE), another machine learning approach for extending differential evolution. The last chapter is dedicated to the state of the art in gene regulatory network (GRN) research as one of the most interesting and active research fields. The author describes an evolving reaction network, which expands the neuro-evolution methodology to produce a type of genetic network suitable for biochemical systems and has succeeded in designing genetic circuits in synthetic biology. The author also presents real-world GRN application to several artificial intelligent tasks, proposing a framework of motion generation by GRNs (MONGERN), which evolves GRNs to operate a real humanoid robot.

Computational Genetic Regulatory Networks: Evolvable, Self-organizing Systems

Computational Genetic Regulatory Networks: Evolvable, Self-organizing Systems

Author: Johannes F. Knabe

Publisher: Springer

Published: 2012-08-14

Total Pages: 125

ISBN-13: 3642302963

DOWNLOAD EBOOK

Genetic Regulatory Networks (GRNs) in biological organisms are primary engines for cells to enact their engagements with environments, via incessant, continually active coupling. In differentiated multicellular organisms, tremendous complexity has arisen in the course of evolution of life on earth. Engineering and science have so far achieved no working system that can compare with this complexity, depth and scope of organization. Abstracting the dynamics of genetic regulatory control to a computational framework in which artificial GRNs in artificial simulated cells differentiate while connected in a changing topology, it is possible to apply Darwinian evolution in silico to study the capacity of such developmental/differentiated GRNs to evolve. In this volume an evolutionary GRN paradigm is investigated for its evolvability and robustness in models of biological clocks, in simple differentiated multicellularity, and in evolving artificial developing 'organisms' which grow and express an ontogeny starting from a single cell interacting with its environment, eventually including a changing local neighbourhood of other cells. These methods may help us understand the genesis, organization, adaptive plasticity, and evolvability of differentiated biological systems, and may also provide a paradigm for transferring these principles of biology's success to computational and engineering challenges at a scale not previously conceivable.


Book Synopsis Computational Genetic Regulatory Networks: Evolvable, Self-organizing Systems by : Johannes F. Knabe

Download or read book Computational Genetic Regulatory Networks: Evolvable, Self-organizing Systems written by Johannes F. Knabe and published by Springer. This book was released on 2012-08-14 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Regulatory Networks (GRNs) in biological organisms are primary engines for cells to enact their engagements with environments, via incessant, continually active coupling. In differentiated multicellular organisms, tremendous complexity has arisen in the course of evolution of life on earth. Engineering and science have so far achieved no working system that can compare with this complexity, depth and scope of organization. Abstracting the dynamics of genetic regulatory control to a computational framework in which artificial GRNs in artificial simulated cells differentiate while connected in a changing topology, it is possible to apply Darwinian evolution in silico to study the capacity of such developmental/differentiated GRNs to evolve. In this volume an evolutionary GRN paradigm is investigated for its evolvability and robustness in models of biological clocks, in simple differentiated multicellularity, and in evolving artificial developing 'organisms' which grow and express an ontogeny starting from a single cell interacting with its environment, eventually including a changing local neighbourhood of other cells. These methods may help us understand the genesis, organization, adaptive plasticity, and evolvability of differentiated biological systems, and may also provide a paradigm for transferring these principles of biology's success to computational and engineering challenges at a scale not previously conceivable.

Genetic Programming

Genetic Programming

Author: Mauro Castelli

Publisher: Springer

Published: 2018-03-23

Total Pages: 331

ISBN-13: 3319775537

DOWNLOAD EBOOK

This book constitutes the refereed proceedings of the 21st European Conference on Genetic Programming, EuroGP 2018, held in Parma, Italy, in April 2018, co-located with the Evo* 2018 events, EvoCOP, EvoMUSART, and EvoApplications. The 11 revised full papers presented together with 8 poster papers were carefully reviewed and selected from 36 submissions. The wide range of topics in this volume reflects the current state of research in the field. Thus, we see topics and applications including analysis of feature importance for metabolomics, semantic methods, evolution of boolean networks, generation of redundant features, ensembles of GP models, automatic design of grammatical representations, GP and neuroevolution, visual reinforcement learning, evolution of deep neural networks, evolution of graphs, and scheduling in heterogeneous networks.


Book Synopsis Genetic Programming by : Mauro Castelli

Download or read book Genetic Programming written by Mauro Castelli and published by Springer. This book was released on 2018-03-23 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 21st European Conference on Genetic Programming, EuroGP 2018, held in Parma, Italy, in April 2018, co-located with the Evo* 2018 events, EvoCOP, EvoMUSART, and EvoApplications. The 11 revised full papers presented together with 8 poster papers were carefully reviewed and selected from 36 submissions. The wide range of topics in this volume reflects the current state of research in the field. Thus, we see topics and applications including analysis of feature importance for metabolomics, semantic methods, evolution of boolean networks, generation of redundant features, ensembles of GP models, automatic design of grammatical representations, GP and neuroevolution, visual reinforcement learning, evolution of deep neural networks, evolution of graphs, and scheduling in heterogeneous networks.

Evolutionary Computation in Gene Regulatory Network Research

Evolutionary Computation in Gene Regulatory Network Research

Author: Hitoshi Iba

Publisher: John Wiley & Sons

Published: 2016-02-23

Total Pages: 464

ISBN-13: 1118911512

DOWNLOAD EBOOK

Introducing a handbook for gene regulatory network research using evolutionary computation, with applications for computer scientists, computational and system biologists This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics. • Provides a reference for current and future research in gene regulatory networks (GRN) using evolutionary computation (EC) • Covers sub-domains of GRN research using EC, such as expression profile analysis, reverse engineering, GRN evolution, applications • Contains useful contents for courses in gene regulatory networks, systems biology, computational biology, and synthetic biology • Delivers state-of-the-art research in genetic algorithms, genetic programming, and swarm intelligence Evolutionary Computation in Gene Regulatory Network Research is a reference for researchers and professionals in computer science, systems biology, and bioinformatics, as well as upper undergraduate, graduate, and postgraduate students. Hitoshi Iba is a Professor in the Department of Information and Communication Engineering, Graduate School of Information Science and Technology, at the University of Tokyo, Toyko, Japan. He is an Associate Editor of the IEEE Transactions on Evolutionary Computation and the journal of Genetic Programming and Evolvable Machines. Nasimul Noman is a lecturer in the School of Electrical Engineering and Computer Science at the University of Newcastle, NSW, Australia. From 2002 to 2012 he was a faculty member at the University of Dhaka, Bangladesh. Noman is an Editor of the BioMed Research International journal. His research interests include computational biology, synthetic biology, and bioinformatics.


Book Synopsis Evolutionary Computation in Gene Regulatory Network Research by : Hitoshi Iba

Download or read book Evolutionary Computation in Gene Regulatory Network Research written by Hitoshi Iba and published by John Wiley & Sons. This book was released on 2016-02-23 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing a handbook for gene regulatory network research using evolutionary computation, with applications for computer scientists, computational and system biologists This book is a step-by-step guideline for research in gene regulatory networks (GRN) using evolutionary computation (EC). The book is organized into four parts that deliver materials in a way equally attractive for a reader with training in computation or biology. Each of these sections, authored by well-known researchers and experienced practitioners, provides the relevant materials for the interested readers. The first part of this book contains an introductory background to the field. The second part presents the EC approaches for analysis and reconstruction of GRN from gene expression data. The third part of this book covers the contemporary advancements in the automatic construction of gene regulatory and reaction networks and gives direction and guidelines for future research. Finally, the last part of this book focuses on applications of GRNs with EC in other fields, such as design, engineering and robotics. • Provides a reference for current and future research in gene regulatory networks (GRN) using evolutionary computation (EC) • Covers sub-domains of GRN research using EC, such as expression profile analysis, reverse engineering, GRN evolution, applications • Contains useful contents for courses in gene regulatory networks, systems biology, computational biology, and synthetic biology • Delivers state-of-the-art research in genetic algorithms, genetic programming, and swarm intelligence Evolutionary Computation in Gene Regulatory Network Research is a reference for researchers and professionals in computer science, systems biology, and bioinformatics, as well as upper undergraduate, graduate, and postgraduate students. Hitoshi Iba is a Professor in the Department of Information and Communication Engineering, Graduate School of Information Science and Technology, at the University of Tokyo, Toyko, Japan. He is an Associate Editor of the IEEE Transactions on Evolutionary Computation and the journal of Genetic Programming and Evolvable Machines. Nasimul Noman is a lecturer in the School of Electrical Engineering and Computer Science at the University of Newcastle, NSW, Australia. From 2002 to 2012 he was a faculty member at the University of Dhaka, Bangladesh. Noman is an Editor of the BioMed Research International journal. His research interests include computational biology, synthetic biology, and bioinformatics.

Handbook of Research on Computational Methodologies in Gene Regulatory Networks

Handbook of Research on Computational Methodologies in Gene Regulatory Networks

Author: Das, Sanjoy

Publisher: IGI Global

Published: 2009-10-31

Total Pages: 740

ISBN-13: 1605666866

DOWNLOAD EBOOK

"This book focuses on methods widely used in modeling gene networks including structure discovery, learning, and optimization"--Provided by publisher.


Book Synopsis Handbook of Research on Computational Methodologies in Gene Regulatory Networks by : Das, Sanjoy

Download or read book Handbook of Research on Computational Methodologies in Gene Regulatory Networks written by Das, Sanjoy and published by IGI Global. This book was released on 2009-10-31 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book focuses on methods widely used in modeling gene networks including structure discovery, learning, and optimization"--Provided by publisher.

New Frontier In Evolutionary Algorithms: Theory And Applications

New Frontier In Evolutionary Algorithms: Theory And Applications

Author: Iba Hitoshi

Publisher: Imperial College Press

Published: 2011-08-26

Total Pages: 316

ISBN-13: 1911299557

DOWNLOAD EBOOK

This book delivers theoretical and practical knowledge of Genetic Algorithms (GA) for the purpose of practical applications. It provides a methodology for a GA-based search strategy with the integration of several Artificial Life and Artificial Intelligence techniques, such as memetic concepts, swarm intelligence, and foraging strategies. The development of such tools contributes to better optimizing methodologies when addressing tasks from areas such as robotics, financial forecasting, and data mining in bioinformatics.The emphasis of this book is on applicability to the real world. Tasks from application areas - optimization of the trading rule in foreign exchange (FX) and stock prices, economic load dispatch in power system, exit/door placement for evacuation planning, and gene regulatory network inference in bioinformatics - are studied, and the resultant empirical investigations demonstrate how successful the proposed approaches are when solving real-world tasks of great importance.


Book Synopsis New Frontier In Evolutionary Algorithms: Theory And Applications by : Iba Hitoshi

Download or read book New Frontier In Evolutionary Algorithms: Theory And Applications written by Iba Hitoshi and published by Imperial College Press. This book was released on 2011-08-26 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book delivers theoretical and practical knowledge of Genetic Algorithms (GA) for the purpose of practical applications. It provides a methodology for a GA-based search strategy with the integration of several Artificial Life and Artificial Intelligence techniques, such as memetic concepts, swarm intelligence, and foraging strategies. The development of such tools contributes to better optimizing methodologies when addressing tasks from areas such as robotics, financial forecasting, and data mining in bioinformatics.The emphasis of this book is on applicability to the real world. Tasks from application areas - optimization of the trading rule in foreign exchange (FX) and stock prices, economic load dispatch in power system, exit/door placement for evacuation planning, and gene regulatory network inference in bioinformatics - are studied, and the resultant empirical investigations demonstrate how successful the proposed approaches are when solving real-world tasks of great importance.

The Regulatory Genome

The Regulatory Genome

Author: Eric H. Davidson

Publisher: Elsevier

Published: 2010-07-19

Total Pages: 304

ISBN-13: 9780080455570

DOWNLOAD EBOOK

Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams


Book Synopsis The Regulatory Genome by : Eric H. Davidson

Download or read book The Regulatory Genome written by Eric H. Davidson and published by Elsevier. This book was released on 2010-07-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams

Artificial Life and Evolutionary Computation

Artificial Life and Evolutionary Computation

Author:

Publisher:

Published:

Total Pages:

ISBN-13: 9814466743

DOWNLOAD EBOOK


Book Synopsis Artificial Life and Evolutionary Computation by :

Download or read book Artificial Life and Evolutionary Computation written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: