Evolutionary Genetics

Evolutionary Genetics

Author: Glenn-Peter Sætre

Publisher: Oxford University Press, USA

Published: 2019-05

Total Pages: 327

ISBN-13: 0198830912

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Evolutionary genetics is the study of how genetic variation leads to evolutionary change. With the recent explosion in the availability of whole genome sequence data, vast quantities of genetic data are being generated at an ever-increasing pace with the result that programming has become an essential tool for researchers. Most importantly, a thorough understanding of evolutionary principles is essential for making sense of this genetic data. This up-to-date textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation, together with their consequences. The book also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Furthermore, at the end of each chapter, study questions are provided to motivate the reader to think and reflect on the concepts introduced. Practical experience is essential when it comes to developing an understanding of how to use genetic and genomic data to analyze and address interesting questions in the life sciences and how to interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and the analysis of evolutionary genetic data. The R environment stands out as an ideal all-purpose, open source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduce readers to the plethora of molecular and analytical methods that have only recently become available.


Book Synopsis Evolutionary Genetics by : Glenn-Peter Sætre

Download or read book Evolutionary Genetics written by Glenn-Peter Sætre and published by Oxford University Press, USA. This book was released on 2019-05 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary genetics is the study of how genetic variation leads to evolutionary change. With the recent explosion in the availability of whole genome sequence data, vast quantities of genetic data are being generated at an ever-increasing pace with the result that programming has become an essential tool for researchers. Most importantly, a thorough understanding of evolutionary principles is essential for making sense of this genetic data. This up-to-date textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation, together with their consequences. The book also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Furthermore, at the end of each chapter, study questions are provided to motivate the reader to think and reflect on the concepts introduced. Practical experience is essential when it comes to developing an understanding of how to use genetic and genomic data to analyze and address interesting questions in the life sciences and how to interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and the analysis of evolutionary genetic data. The R environment stands out as an ideal all-purpose, open source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduce readers to the plethora of molecular and analytical methods that have only recently become available.

Human Evolutionary Genetics

Human Evolutionary Genetics

Author: Mark Jobling

Publisher: Garland Science

Published: 2013-06-25

Total Pages: 1557

ISBN-13: 1317952251

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Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h


Book Synopsis Human Evolutionary Genetics by : Mark Jobling

Download or read book Human Evolutionary Genetics written by Mark Jobling and published by Garland Science. This book was released on 2013-06-25 with total page 1557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h

Elements of Evolutionary Genetics

Elements of Evolutionary Genetics

Author: Brian Charlesworth

Publisher: Roberts

Published: 2010-02-03

Total Pages: 776

ISBN-13:

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This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure.


Book Synopsis Elements of Evolutionary Genetics by : Brian Charlesworth

Download or read book Elements of Evolutionary Genetics written by Brian Charlesworth and published by Roberts. This book was released on 2010-02-03 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure.

Molecular Evolutionary Genetics

Molecular Evolutionary Genetics

Author: Masatoshi Nei

Publisher: Columbia University Press

Published: 1987

Total Pages: 526

ISBN-13: 9780231063210

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-- "The Scientist"


Book Synopsis Molecular Evolutionary Genetics by : Masatoshi Nei

Download or read book Molecular Evolutionary Genetics written by Masatoshi Nei and published by Columbia University Press. This book was released on 1987 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: -- "The Scientist"

Molecular Methods for Evolutionary Genetics

Molecular Methods for Evolutionary Genetics

Author: Virginie Orgogozo

Publisher: Humana Press

Published: 2011-03-15

Total Pages: 503

ISBN-13: 9781617792274

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We are entering a particularly fruitful period in evolutionary genetics, as rapid technological progress transforms the investigation of genetic variation within and between species. Molecular Methods for Evolutionary Genetics is a collection of advanced molecular biology protocols and general overviews intended to represent the essential methods currently bringing evolutionary genetics to fruition. Divided into six thematic sections, this volume covers methods for characterizing genomes, diverse approaches to enrich DNA for subsets of the genome prior to sequencing, and state-of-the-art protocols for sampling genetic variation for genetic mapping studies and population genetic studies (RAD sequencing, Sequenom, microarrays, etc.). The volume concludes by focusing on methods to study candidate genes, from obtaining their sequences and analyzing their transcripts to experimentally manipulating their activities in vivo. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Molecular Methods for Evolutionary Genetics serves as a rich resource to biologists interested in evolution, whether they be specialists or beginners in molecular biology.


Book Synopsis Molecular Methods for Evolutionary Genetics by : Virginie Orgogozo

Download or read book Molecular Methods for Evolutionary Genetics written by Virginie Orgogozo and published by Humana Press. This book was released on 2011-03-15 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are entering a particularly fruitful period in evolutionary genetics, as rapid technological progress transforms the investigation of genetic variation within and between species. Molecular Methods for Evolutionary Genetics is a collection of advanced molecular biology protocols and general overviews intended to represent the essential methods currently bringing evolutionary genetics to fruition. Divided into six thematic sections, this volume covers methods for characterizing genomes, diverse approaches to enrich DNA for subsets of the genome prior to sequencing, and state-of-the-art protocols for sampling genetic variation for genetic mapping studies and population genetic studies (RAD sequencing, Sequenom, microarrays, etc.). The volume concludes by focusing on methods to study candidate genes, from obtaining their sequences and analyzing their transcripts to experimentally manipulating their activities in vivo. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Molecular Methods for Evolutionary Genetics serves as a rich resource to biologists interested in evolution, whether they be specialists or beginners in molecular biology.

Introduction to Evolutionary Genomics

Introduction to Evolutionary Genomics

Author: Naruya Saitou

Publisher: Springer Science & Business Media

Published: 2014-01-22

Total Pages: 476

ISBN-13: 1447153049

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This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.


Book Synopsis Introduction to Evolutionary Genomics by : Naruya Saitou

Download or read book Introduction to Evolutionary Genomics written by Naruya Saitou and published by Springer Science & Business Media. This book was released on 2014-01-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

Population and Evolutionary Genetics

Population and Evolutionary Genetics

Author: Francisco José Ayala

Publisher: Benjamin-Cummings Publishing Company

Published: 1982

Total Pages: 298

ISBN-13:

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Book Synopsis Population and Evolutionary Genetics by : Francisco José Ayala

Download or read book Population and Evolutionary Genetics written by Francisco José Ayala and published by Benjamin-Cummings Publishing Company. This book was released on 1982 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Founders of Evolutionary Genetics

The Founders of Evolutionary Genetics

Author: S. Sarkar

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 306

ISBN-13: 9401128561

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genetics. " It is simply the appropriation of that term, very likely with insufficient knowledge and respect for its past usage. For that, the Editor alone is responsible and requests tolerance. He has, as far as he can tell, no intention or desire to use it for any historiographical purposes other than that just mentioned. Even more important, the decision to consider Muller together with Fisher, Haldane and Wright is also not original. Crow (1984) has already done so, arguing persua sively that Muller was "keenly interested in evolution and made sub stantial contributions to the development of the neo-Darwinian view. " Crow's reasons for considering these four figures together and the reasons discussed above are complementary. This book continues a historiographical choice he initiated; others will have to judge whether it is appropriate. The foregoing considerations were intended to show why Fisher, Haldane, Muller and Wright should be considered together in the history of theoretical evolutionary genetics. I By a welcome stroke of luck, from the point of view of the Editor, all four of these figures were born almost together, between 1889 and 1892, and almost exactly a century ago. It therefore seemed appropriate to use their birth cente naries to consider their work together. A conference was held at Boston University, on March 6, 1990, under the auspices of the Boston Center for the Philosophy and History of Science, to discuss their work. This book has emerged mainly from that conference.


Book Synopsis The Founders of Evolutionary Genetics by : S. Sarkar

Download or read book The Founders of Evolutionary Genetics written by S. Sarkar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: genetics. " It is simply the appropriation of that term, very likely with insufficient knowledge and respect for its past usage. For that, the Editor alone is responsible and requests tolerance. He has, as far as he can tell, no intention or desire to use it for any historiographical purposes other than that just mentioned. Even more important, the decision to consider Muller together with Fisher, Haldane and Wright is also not original. Crow (1984) has already done so, arguing persua sively that Muller was "keenly interested in evolution and made sub stantial contributions to the development of the neo-Darwinian view. " Crow's reasons for considering these four figures together and the reasons discussed above are complementary. This book continues a historiographical choice he initiated; others will have to judge whether it is appropriate. The foregoing considerations were intended to show why Fisher, Haldane, Muller and Wright should be considered together in the history of theoretical evolutionary genetics. I By a welcome stroke of luck, from the point of view of the Editor, all four of these figures were born almost together, between 1889 and 1892, and almost exactly a century ago. It therefore seemed appropriate to use their birth cente naries to consider their work together. A conference was held at Boston University, on March 6, 1990, under the auspices of the Boston Center for the Philosophy and History of Science, to discuss their work. This book has emerged mainly from that conference.

Evolution and Genetics in Life Histories

Evolution and Genetics in Life Histories

Author: H. Dingle

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 249

ISBN-13: 1468462709

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This volume is the result of a symposium entitled "Variation in Life Histories: Genetics and Evolutionary Processes" sponsored by the Program in Evolutionary Ecology and Behavior of the University of Iowa and held in Iowa City on October 13 and 14, 1980. Prompted by a recent upsurge of interest in the evolution of life histories, we chose this topic because of the obvious association between life history traits and Darwinian fit ness. If such an association were to be fruitfully investigated, it would require the closer cooperation of population and evolutionary ecologists and quantitative and population geneticists. To encourage such an association, our symposium had four major aims: first, to facilitate intellectual exchange across disciplines among an array of biologists studying life histories; second, to encourage exploration of genetic variance and covari ance for life history traits; third, to consider the ecological background for genetic vari ability; and finally, to facilitate a comparative overview both within and among species. Obviously such broad aims cannot be met totally in a single volume, but we think we have succeeded reasonably well in providing a representative and nourishing intel lectual feast. We see this book as a stimulus to the coordination of future efforts in an important and expanding area of inquiry. We have divided the book into six sections.


Book Synopsis Evolution and Genetics in Life Histories by : H. Dingle

Download or read book Evolution and Genetics in Life Histories written by H. Dingle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the result of a symposium entitled "Variation in Life Histories: Genetics and Evolutionary Processes" sponsored by the Program in Evolutionary Ecology and Behavior of the University of Iowa and held in Iowa City on October 13 and 14, 1980. Prompted by a recent upsurge of interest in the evolution of life histories, we chose this topic because of the obvious association between life history traits and Darwinian fit ness. If such an association were to be fruitfully investigated, it would require the closer cooperation of population and evolutionary ecologists and quantitative and population geneticists. To encourage such an association, our symposium had four major aims: first, to facilitate intellectual exchange across disciplines among an array of biologists studying life histories; second, to encourage exploration of genetic variance and covari ance for life history traits; third, to consider the ecological background for genetic vari ability; and finally, to facilitate a comparative overview both within and among species. Obviously such broad aims cannot be met totally in a single volume, but we think we have succeeded reasonably well in providing a representative and nourishing intel lectual feast. We see this book as a stimulus to the coordination of future efforts in an important and expanding area of inquiry. We have divided the book into six sections.

Evolutionary Quantitative Genetics

Evolutionary Quantitative Genetics

Author: Derek A. Roff

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 503

ISBN-13: 1461540801

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The impetus for this book arose out of my previous book, The Evolution of Life Histories (Roff, 1992). In that book I presented a single chapter on quanti tative genetic theory. However, as the book was concerned with the evolution of life histories and traits connected to this, the presence of quantitative genetic variation was an underlying theme throughout. Much of the focus was placed on optimality theory, for it is this approach that has proven to be extremely successful in the analysis of life history variation. But quantitative genetics cannot be ig nored, because there are some questions for which optimality approaches are inappropriate; for example, although optimality modeling can address the ques tion of the maintenance of phenotypic variation, it cannot say anything about genetic variation, on which further evolution clearly depends. The present book is, thus, a natural extension of the first. I have approached the problem not from the point of view of an animal or plant breeder but from that of one interested in understanding the evolution of quantitative traits in wild populations. The subject is large with a considerable body of theory: I generally present the assumptions underlying the analysis and the results, giving the relevant references for those interested in the intervening mathematics. My interest is in what quantitative genetics tells me about evolutionary processes; therefore, I have concentrated on areas of research most relevant to field studies.


Book Synopsis Evolutionary Quantitative Genetics by : Derek A. Roff

Download or read book Evolutionary Quantitative Genetics written by Derek A. Roff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impetus for this book arose out of my previous book, The Evolution of Life Histories (Roff, 1992). In that book I presented a single chapter on quanti tative genetic theory. However, as the book was concerned with the evolution of life histories and traits connected to this, the presence of quantitative genetic variation was an underlying theme throughout. Much of the focus was placed on optimality theory, for it is this approach that has proven to be extremely successful in the analysis of life history variation. But quantitative genetics cannot be ig nored, because there are some questions for which optimality approaches are inappropriate; for example, although optimality modeling can address the ques tion of the maintenance of phenotypic variation, it cannot say anything about genetic variation, on which further evolution clearly depends. The present book is, thus, a natural extension of the first. I have approached the problem not from the point of view of an animal or plant breeder but from that of one interested in understanding the evolution of quantitative traits in wild populations. The subject is large with a considerable body of theory: I generally present the assumptions underlying the analysis and the results, giving the relevant references for those interested in the intervening mathematics. My interest is in what quantitative genetics tells me about evolutionary processes; therefore, I have concentrated on areas of research most relevant to field studies.