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Extracellular Matrix Influences on Gene Expression

Author: Harold Slavkin

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 876

ISBN-13: 0323142141

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Extracellular Matrix Influences on Gene Expression emerged from the Second international Santa Catalina Island Colloquium that deals with the discussion on the advances in the molecular biology of extracellular matrices and the epigenetic influences on cell function. Topics discussed include morphological descriptions, genetics, teratology, collagen heterogeneity, and mineralization. The book's 12 chapters discuss the chromosomal and extrachromosomal influences upon transcription, translational and post-translational regulations during development, and regulation of extracellular matrix molecular biosynthesis. The book describes the regulation of tissue-specific collagen biosynthesis and the extracellular matrix macromolecules. It contains papers that explain the outer cell surface specificity and cell interactions. Because there are advances as well in other specific topics, such as the epithelial-masenchymal interactions and extracellular matrix influences on gene expression, this book contains papers that deal with these subject matters. Furthermore, it explains the matrix-cell and cell-matrix interactions and mineralization processes, as well as the aberrations in developmental processes. This book will be useful to those individuals who study the scientific advances in developmental biology.

Book Synopsis Extracellular Matrix Influences on Gene Expression by : Harold Slavkin

Download or read book Extracellular Matrix Influences on Gene Expression written by Harold Slavkin and published by Elsevier. This book was released on 2012-12-02 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular Matrix Influences on Gene Expression emerged from the Second international Santa Catalina Island Colloquium that deals with the discussion on the advances in the molecular biology of extracellular matrices and the epigenetic influences on cell function. Topics discussed include morphological descriptions, genetics, teratology, collagen heterogeneity, and mineralization. The book's 12 chapters discuss the chromosomal and extrachromosomal influences upon transcription, translational and post-translational regulations during development, and regulation of extracellular matrix molecular biosynthesis. The book describes the regulation of tissue-specific collagen biosynthesis and the extracellular matrix macromolecules. It contains papers that explain the outer cell surface specificity and cell interactions. Because there are advances as well in other specific topics, such as the epithelial-masenchymal interactions and extracellular matrix influences on gene expression, this book contains papers that deal with these subject matters. Furthermore, it explains the matrix-cell and cell-matrix interactions and mineralization processes, as well as the aberrations in developmental processes. This book will be useful to those individuals who study the scientific advances in developmental biology.

Extracellular Matrix in Development

Author: Douglas W. DeSimone

Publisher: Springer Science & Business Media

Published: 2013-03-15

Total Pages: 260

ISBN-13: 3642359353

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Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

Book Synopsis Extracellular Matrix in Development by : Douglas W. DeSimone

Download or read book Extracellular Matrix in Development written by Douglas W. DeSimone and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

Molecular Biology of The Cell

Author: Bruce Alberts

Publisher:

Published: 2002

Total Pages: 0

ISBN-13: 9780815332183

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Effects of Extracellular Matrix Components on Chondrocyte Gene Expression

Author: John Terrig Thomas

Publisher:

Published: 1988

Total Pages:

ISBN-13:

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Book Synopsis The Effects of Extracellular Matrix Components on Chondrocyte Gene Expression by : John Terrig Thomas

Download or read book The Effects of Extracellular Matrix Components on Chondrocyte Gene Expression written by John Terrig Thomas and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Extracellular Matrix: an Overview

Author: Robert Mecham

Publisher: Springer Science & Business Media

Published: 2011-02-16

Total Pages: 429

ISBN-13: 3642165559

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Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Book Synopsis The Extracellular Matrix: an Overview by : Robert Mecham

Download or read book The Extracellular Matrix: an Overview written by Robert Mecham and published by Springer Science & Business Media. This book was released on 2011-02-16 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Gene Expression in the Third Dimension

Author:

Publisher:

Published: 2009

Total Pages:

ISBN-13:

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Decades ago, we and others proposed that the dynamic interplay between a cell and its surrounding environment dictates cell phenotype and tissue structure. Whereas much has been discovered about the effects of extracellular matrix molecules on cell growth and tissue specific gene expression, the nuclear mechanisms through which these molecules promote these physiological events remain unknown. Using mammary epithelial cells as a model, the purpose of this review is to discuss how the extracellular matrix influences nuclear structure and function in a three-dimensional context to promote epithelial morphogenesis and function in the mammary gland.

Book Synopsis Gene Expression in the Third Dimension by :

Download or read book Gene Expression in the Third Dimension written by and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Decades ago, we and others proposed that the dynamic interplay between a cell and its surrounding environment dictates cell phenotype and tissue structure. Whereas much has been discovered about the effects of extracellular matrix molecules on cell growth and tissue specific gene expression, the nuclear mechanisms through which these molecules promote these physiological events remain unknown. Using mammary epithelial cells as a model, the purpose of this review is to discuss how the extracellular matrix influences nuclear structure and function in a three-dimensional context to promote epithelial morphogenesis and function in the mammary gland.

Effects of Substratum Surface Chemistry and Topography on Extracellular Matrix Gene Expression

Author: Laisheng Chou

Publisher:

Published: 1997

Total Pages: 172

ISBN-13:

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Book Synopsis Effects of Substratum Surface Chemistry and Topography on Extracellular Matrix Gene Expression by : Laisheng Chou

Download or read book Effects of Substratum Surface Chemistry and Topography on Extracellular Matrix Gene Expression written by Laisheng Chou and published by . This book was released on 1997 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Effects of the Extracellular Matrix on Hepatocyte Gene Expression and Its Regulation of the Low Density Lipoprotein Receptor-related Protein

Author:

Publisher:

Published: 2000

Total Pages:

ISBN-13:

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Book Synopsis Effects of the Extracellular Matrix on Hepatocyte Gene Expression and Its Regulation of the Low Density Lipoprotein Receptor-related Protein by :

Download or read book Effects of the Extracellular Matrix on Hepatocyte Gene Expression and Its Regulation of the Low Density Lipoprotein Receptor-related Protein written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Extracellular Matrix Influence in Streptococcus Mutans Gene Expression in a Cariogenic Biofilm

Author:

Publisher:

Published: 2018

Total Pages:

ISBN-13:

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Book Synopsis Extracellular Matrix Influence in Streptococcus Mutans Gene Expression in a Cariogenic Biofilm by :

Download or read book Extracellular Matrix Influence in Streptococcus Mutans Gene Expression in a Cariogenic Biofilm written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Of Extracellular Matrix, Scaffolds, and Signaling

Author:

Publisher:

Published: 2006

Total Pages:

ISBN-13:

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The microenvironment surrounding cells influences gene expression, such that a cell's behavior is largely determined by its interactions with the extracellular matrix, neighboring cells, and soluble cues released locally or by distant tissues. We describe the essential role of context and organ structure in directing mammary gland development and differentiated function, and in determining response to oncogenic insults including mutations. We expand on the concept of 'dynamic reciprocity' to present an integrated view of development, cancer, and aging, and posit that genes are like piano keys: while essential, it is the context that makes the music.

Book Synopsis Of Extracellular Matrix, Scaffolds, and Signaling by :

Download or read book Of Extracellular Matrix, Scaffolds, and Signaling written by and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The microenvironment surrounding cells influences gene expression, such that a cell's behavior is largely determined by its interactions with the extracellular matrix, neighboring cells, and soluble cues released locally or by distant tissues. We describe the essential role of context and organ structure in directing mammary gland development and differentiated function, and in determining response to oncogenic insults including mutations. We expand on the concept of 'dynamic reciprocity' to present an integrated view of development, cancer, and aging, and posit that genes are like piano keys: while essential, it is the context that makes the music.