Focus on Atherosclerosis Research

Focus on Atherosclerosis Research

Author: Leon V. Clark

Publisher: Nova Publishers

Published: 2004

Total Pages: 274

ISBN-13: 9781594540448

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Atherosclerosis is a degenerative condition in which arteries build up deposits called plaques (atheromas) which consist of lipids (mainly cholesterol), connective tissue and smooth muscle cells originating from the arterial wall. Plaques develop quietly over a period of years and are unnoticeable until there is an interruption in the normal flow of blood. Plaques may partially or totally block the blood's flow through an artery. Two things that can happen where plaques occur are: bleeding (hemorrhage) into the plaque; and formation of a blood clot (thrombus) on the plaque's surface. Atherosclerosis affects large and medium-sized arteries. The type of artery and where the plaque develops varies with each person. Atherosclerosis research has witnessed startling progress in recent years, partially due to new drugs as well as to new breakthroughs in molecular medicine.


Book Synopsis Focus on Atherosclerosis Research by : Leon V. Clark

Download or read book Focus on Atherosclerosis Research written by Leon V. Clark and published by Nova Publishers. This book was released on 2004 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis is a degenerative condition in which arteries build up deposits called plaques (atheromas) which consist of lipids (mainly cholesterol), connective tissue and smooth muscle cells originating from the arterial wall. Plaques develop quietly over a period of years and are unnoticeable until there is an interruption in the normal flow of blood. Plaques may partially or totally block the blood's flow through an artery. Two things that can happen where plaques occur are: bleeding (hemorrhage) into the plaque; and formation of a blood clot (thrombus) on the plaque's surface. Atherosclerosis affects large and medium-sized arteries. The type of artery and where the plaque develops varies with each person. Atherosclerosis research has witnessed startling progress in recent years, partially due to new drugs as well as to new breakthroughs in molecular medicine.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease

Author: Robert Fitridge

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 589

ISBN-13: 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.


Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Textbook of Vascular Medicine

Textbook of Vascular Medicine

Author: Rhian M. Touyz

Publisher: Springer

Published: 2019-08-02

Total Pages: 503

ISBN-13: 3030164810

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This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.


Book Synopsis Textbook of Vascular Medicine by : Rhian M. Touyz

Download or read book Textbook of Vascular Medicine written by Rhian M. Touyz and published by Springer. This book was released on 2019-08-02 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.

Recent Progress in Atherosclerosis Research

Recent Progress in Atherosclerosis Research

Author: E. Vollmer

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 261

ISBN-13: 3642768490

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This monograph on recent progress in atherosclerosis research presents state-of-the art morphological investigations on the cells and their metabolism in the atherosclerotic plaque in situ. The spectrum of methods includes immunohistologic and immunoelectron microscopic investigations on the localization of apolipoproteins in the cells of the arterial intima, presenting new data on the lipoprotein metabolism in plaque. The collagen metabolism is analysed by in situ hybridization techniques for demonstrating the synthesis of different collagen types on the messenger RNA level. Concentrating on in situ investigations with sophisticated morpholocial methods, the widespread discussion on atherogenesis is focused on the arterial wall and its morphological alterations. As morphology remains the basis for understanding the pathogenesis of disease, the results presented here could be of interest not only to pathologists, but also to clinicians and researchers working in the field of biology of atherosclerosis.


Book Synopsis Recent Progress in Atherosclerosis Research by : E. Vollmer

Download or read book Recent Progress in Atherosclerosis Research written by E. Vollmer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph on recent progress in atherosclerosis research presents state-of-the art morphological investigations on the cells and their metabolism in the atherosclerotic plaque in situ. The spectrum of methods includes immunohistologic and immunoelectron microscopic investigations on the localization of apolipoproteins in the cells of the arterial intima, presenting new data on the lipoprotein metabolism in plaque. The collagen metabolism is analysed by in situ hybridization techniques for demonstrating the synthesis of different collagen types on the messenger RNA level. Concentrating on in situ investigations with sophisticated morpholocial methods, the widespread discussion on atherogenesis is focused on the arterial wall and its morphological alterations. As morphology remains the basis for understanding the pathogenesis of disease, the results presented here could be of interest not only to pathologists, but also to clinicians and researchers working in the field of biology of atherosclerosis.

Atlas of Atherosclerosis

Atlas of Atherosclerosis

Author: Peter W.F. Wilson

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 285

ISBN-13: 1461564840

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We are in the early years of a new millen Tremendous interest is now focused on nium and atherosclerotic disease is now the characteristics of atherosclerotic thought to underlie more adult deaths plaques, as we recognize that many clinical than any other disease on the planet. The coronary events are attributable to unstable lifetime burden of risk is high, and lesions that do not cause severe stenoses but Framingham data suggest that approxi are prone to rupture and precipitate angina mately 50% of men and 30% of women pectoris or a myocardial infarction. A vari will experience coronary heart disease ety of factors are under study to help deter during their lifetime. This process begins mine what affects the balance between at a young age, and autopsies of casualties plaque stability and instability. Some of this from the Korean and Vietnam wars as well research is fueled by the fact that therapy for as accident victims in more recent times dyslipidemia often has effects that are not have shown that fatty streak lesions are related to the lipoprotein cholesterol alter very common in young adults. Recent ations, but stem from the pleiotropic effects research has extended these pathologic of such medications on hematologic and studies to investigate the dynamics and inflammatory mechanisms. milieu that foster the creation of these The current volume focuses on the early lesions.


Book Synopsis Atlas of Atherosclerosis by : Peter W.F. Wilson

Download or read book Atlas of Atherosclerosis written by Peter W.F. Wilson and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are in the early years of a new millen Tremendous interest is now focused on nium and atherosclerotic disease is now the characteristics of atherosclerotic thought to underlie more adult deaths plaques, as we recognize that many clinical than any other disease on the planet. The coronary events are attributable to unstable lifetime burden of risk is high, and lesions that do not cause severe stenoses but Framingham data suggest that approxi are prone to rupture and precipitate angina mately 50% of men and 30% of women pectoris or a myocardial infarction. A vari will experience coronary heart disease ety of factors are under study to help deter during their lifetime. This process begins mine what affects the balance between at a young age, and autopsies of casualties plaque stability and instability. Some of this from the Korean and Vietnam wars as well research is fueled by the fact that therapy for as accident victims in more recent times dyslipidemia often has effects that are not have shown that fatty streak lesions are related to the lipoprotein cholesterol alter very common in young adults. Recent ations, but stem from the pleiotropic effects research has extended these pathologic of such medications on hematologic and studies to investigate the dynamics and inflammatory mechanisms. milieu that foster the creation of these The current volume focuses on the early lesions.

Fundamentals of Vascular Biology

Fundamentals of Vascular Biology

Author: Margarethe Geiger

Publisher: Springer

Published: 2019-05-08

Total Pages: 392

ISBN-13: 3030122700

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This well-structured textbook offers essential knowledge on the vascular system. The reader will learn the properties, basic cellular mechanisms and development of the different parts of the vascular system (including the heart), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, in animal models, and ex vivo. This book is based on a PhD Course for students from various bioscientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master ́s Students in vascular biology and biomedicine in general and a helpful tool for young researchers world-wide wishing to gain or refresh their knowledge in this field.


Book Synopsis Fundamentals of Vascular Biology by : Margarethe Geiger

Download or read book Fundamentals of Vascular Biology written by Margarethe Geiger and published by Springer. This book was released on 2019-05-08 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-structured textbook offers essential knowledge on the vascular system. The reader will learn the properties, basic cellular mechanisms and development of the different parts of the vascular system (including the heart), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, in animal models, and ex vivo. This book is based on a PhD Course for students from various bioscientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master ́s Students in vascular biology and biomedicine in general and a helpful tool for young researchers world-wide wishing to gain or refresh their knowledge in this field.

Studies on Atherosclerosis

Studies on Atherosclerosis

Author: Martin Rodriguez-Porcel

Publisher: Springer

Published: 2016-12-22

Total Pages: 138

ISBN-13: 1489976930

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This volume explores the role free radicals and antioxidants within the development of vascular disease, examining fundamental research and translating preclinical knowledge to clinical trials. The expertly authored chapters describe the relationship of oxidative stress to atherosclerosis and the cardiovascular system, exploring its role in cardiac fibrosis, renovascular disease, hypertension, and regulation of blood pressure and cerebral vascular tone. The concluding chapter discusses the current state of clinical research, contextualizing clinical trials within the existing theoretical framework and analyzing attempts to preserve oxidant stress under various conditions. With its concise and authoritative analysis of pre-clinical research and clinical results, Studies in Atherosclerosis – part of the bestselling Oxidative Stress in Basic Research and Clinical Practice series – is essential for researchers and clinicians focusing in cardiology, nephrology, or oxidative stress.


Book Synopsis Studies on Atherosclerosis by : Martin Rodriguez-Porcel

Download or read book Studies on Atherosclerosis written by Martin Rodriguez-Porcel and published by Springer. This book was released on 2016-12-22 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the role free radicals and antioxidants within the development of vascular disease, examining fundamental research and translating preclinical knowledge to clinical trials. The expertly authored chapters describe the relationship of oxidative stress to atherosclerosis and the cardiovascular system, exploring its role in cardiac fibrosis, renovascular disease, hypertension, and regulation of blood pressure and cerebral vascular tone. The concluding chapter discusses the current state of clinical research, contextualizing clinical trials within the existing theoretical framework and analyzing attempts to preserve oxidant stress under various conditions. With its concise and authoritative analysis of pre-clinical research and clinical results, Studies in Atherosclerosis – part of the bestselling Oxidative Stress in Basic Research and Clinical Practice series – is essential for researchers and clinicians focusing in cardiology, nephrology, or oxidative stress.

Cellular and Molecular Biology of Atherosclerosis

Cellular and Molecular Biology of Atherosclerosis

Author: Antonio M. Jr. Gotto

Publisher: Springer

Published: 2011-11-23

Total Pages: 180

ISBN-13: 9781447119111

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Atherosclerotic cardiovascular disease remains the major cause of death and disability in Western society. The field of atherosclerosis research has grown tremendously over the last forty years, shedding a great deal of light on the contributing factors and natural history of the disorder and enabling strategies for its treatment and prevention. Some of the greatest strides in this field in recent years have derived from advances in molecular biology techniques. These strides were chosen for emphasis in the most recent Princess Lilian symposium, whose proceedings this volume represents. Historically, the Princess Lilian meetings have been small ones aimed at bringing together investigators from diverse specialties to discuss a particular subject. The most recent meeting was no exception and included clinicians, clinical investigators, and research ers in basic science. The symposium began with an extensive review of coronary morphopathological findings in patients who died of coronary heart disease. Any rational hypothesis of atherogenesis must take into account clinical findings, and any attempt to bridge the gap between experimental laboratory findings and studies in man is highly desirable. Three chapters focus on endothelial injury: one on the nitric oxide pathway in physiology and pathology, a second on the activation of endothelial cells, and a third on the monocyte and endothelial injury. Still another chapter examines growth factors, in particular the fibroblast growth factor in atherogenesis.


Book Synopsis Cellular and Molecular Biology of Atherosclerosis by : Antonio M. Jr. Gotto

Download or read book Cellular and Molecular Biology of Atherosclerosis written by Antonio M. Jr. Gotto and published by Springer. This book was released on 2011-11-23 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerotic cardiovascular disease remains the major cause of death and disability in Western society. The field of atherosclerosis research has grown tremendously over the last forty years, shedding a great deal of light on the contributing factors and natural history of the disorder and enabling strategies for its treatment and prevention. Some of the greatest strides in this field in recent years have derived from advances in molecular biology techniques. These strides were chosen for emphasis in the most recent Princess Lilian symposium, whose proceedings this volume represents. Historically, the Princess Lilian meetings have been small ones aimed at bringing together investigators from diverse specialties to discuss a particular subject. The most recent meeting was no exception and included clinicians, clinical investigators, and research ers in basic science. The symposium began with an extensive review of coronary morphopathological findings in patients who died of coronary heart disease. Any rational hypothesis of atherogenesis must take into account clinical findings, and any attempt to bridge the gap between experimental laboratory findings and studies in man is highly desirable. Three chapters focus on endothelial injury: one on the nitric oxide pathway in physiology and pathology, a second on the activation of endothelial cells, and a third on the monocyte and endothelial injury. Still another chapter examines growth factors, in particular the fibroblast growth factor in atherogenesis.

Inflammatory Atherosclerosis

Inflammatory Atherosclerosis

Author: Richard James Frink

Publisher: Heart Research Foundation Sacrament

Published: 2002

Total Pages: 136

ISBN-13:

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Book Synopsis Inflammatory Atherosclerosis by : Richard James Frink

Download or read book Inflammatory Atherosclerosis written by Richard James Frink and published by Heart Research Foundation Sacrament. This book was released on 2002 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biochemistry of Atherosclerosis

Biochemistry of Atherosclerosis

Author: Sukhinder C. Kaur

Publisher: Springer Science & Business Media

Published: 2006-08-31

Total Pages: 580

ISBN-13: 0387362797

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This book covers many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. It includes all aspects of the regulation of cholesterol homeostasis and the importance of each pathway. Also explored are the roles of nuclear hormone receptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis. The book further discusses how genetic studies can help understand the complexities that mediate these aspects of atherogenesis.


Book Synopsis Biochemistry of Atherosclerosis by : Sukhinder C. Kaur

Download or read book Biochemistry of Atherosclerosis written by Sukhinder C. Kaur and published by Springer Science & Business Media. This book was released on 2006-08-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. It includes all aspects of the regulation of cholesterol homeostasis and the importance of each pathway. Also explored are the roles of nuclear hormone receptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis. The book further discusses how genetic studies can help understand the complexities that mediate these aspects of atherogenesis.