Formulation of Disperse Systems

Formulation of Disperse Systems

Author: Tharwat F. Tadros

Publisher: John Wiley & Sons

Published: 2014-05-14

Total Pages: 506

ISBN-13: 3527678301

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This book presents comprehensively the science and technology behind the formulation of disperse systems like emulsions, suspensions, foams and others. Starting with a general introduction, the book covers a broad range of topics like the role of different classes of surfactants, stability of disperse systems, formulation of different dispersions, evaluation of formulations and many more. Many examples are included, too. Written by the experienced author and editor Tharwart Tadros, this book is indispensable for every scientist working in the field.


Book Synopsis Formulation of Disperse Systems by : Tharwat F. Tadros

Download or read book Formulation of Disperse Systems written by Tharwat F. Tadros and published by John Wiley & Sons. This book was released on 2014-05-14 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents comprehensively the science and technology behind the formulation of disperse systems like emulsions, suspensions, foams and others. Starting with a general introduction, the book covers a broad range of topics like the role of different classes of surfactants, stability of disperse systems, formulation of different dispersions, evaluation of formulations and many more. Many examples are included, too. Written by the experienced author and editor Tharwart Tadros, this book is indispensable for every scientist working in the field.

Formulation of Disperse Systems

Formulation of Disperse Systems

Author: Tharwat F. Tadros

Publisher: John Wiley & Sons

Published: 2014-08-25

Total Pages: 506

ISBN-13: 3527336826

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This book presents comprehensively the science and technology behind the formulation of disperse systems like emulsions, suspensions, foams and others. Starting with a general introduction, the book covers a broad range of topics like the role of different classes of surfactants, stability of disperse systems, formulation of different dispersions, evaluation of formulations and many more. Many examples are included, too. Written by the experienced author and editor Tharwart Tadros, this book is indispensable for every scientist working in the field.


Book Synopsis Formulation of Disperse Systems by : Tharwat F. Tadros

Download or read book Formulation of Disperse Systems written by Tharwat F. Tadros and published by John Wiley & Sons. This book was released on 2014-08-25 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents comprehensively the science and technology behind the formulation of disperse systems like emulsions, suspensions, foams and others. Starting with a general introduction, the book covers a broad range of topics like the role of different classes of surfactants, stability of disperse systems, formulation of different dispersions, evaluation of formulations and many more. Many examples are included, too. Written by the experienced author and editor Tharwart Tadros, this book is indispensable for every scientist working in the field.

Product Design and Engineering

Product Design and Engineering

Author: Ulrich Bröckel

Publisher: John Wiley & Sons

Published: 2013-08-02

Total Pages: 367

ISBN-13: 3527654763

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Covering the whole value chain - from product requirements and properties via process technologies and equipment to real-world applications - this reference represents a comprehensive overview of the topic. The editors and majority of the authors are members of the European Federation of Chemical Engineering, with backgrounds from academia as well as industry. Therefore, this multifaceted area is highlighted from different angles: essential physico-chemical background, latest measurement and prediction techniques, and numerous applications from cosmetic up to food industry. Recommended reading for process, pharma and chemical engineers, chemists in industry, and those working in the pharmaceutical, food, cosmetics, dyes and pigments industries.


Book Synopsis Product Design and Engineering by : Ulrich Bröckel

Download or read book Product Design and Engineering written by Ulrich Bröckel and published by John Wiley & Sons. This book was released on 2013-08-02 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the whole value chain - from product requirements and properties via process technologies and equipment to real-world applications - this reference represents a comprehensive overview of the topic. The editors and majority of the authors are members of the European Federation of Chemical Engineering, with backgrounds from academia as well as industry. Therefore, this multifaceted area is highlighted from different angles: essential physico-chemical background, latest measurement and prediction techniques, and numerous applications from cosmetic up to food industry. Recommended reading for process, pharma and chemical engineers, chemists in industry, and those working in the pharmaceutical, food, cosmetics, dyes and pigments industries.

Pharmaceutical Dosage Forms

Pharmaceutical Dosage Forms

Author: Herbert Lieberman

Publisher: CRC Press

Published: 2020-08-26

Total Pages: 558

ISBN-13: 1000148416

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Stressing the theory involved in formulating suspensions, emulsions, and colloidal drug products, this Second Edition of a well-received reference test highlights typical formulations, the avoidance of formulation pitfalls, and compliance with established regulatory principles.


Book Synopsis Pharmaceutical Dosage Forms by : Herbert Lieberman

Download or read book Pharmaceutical Dosage Forms written by Herbert Lieberman and published by CRC Press. This book was released on 2020-08-26 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stressing the theory involved in formulating suspensions, emulsions, and colloidal drug products, this Second Edition of a well-received reference test highlights typical formulations, the avoidance of formulation pitfalls, and compliance with established regulatory principles.

Essential Pharmaceutics

Essential Pharmaceutics

Author: Ashlee D. Brunaugh

Publisher: Springer Nature

Published: 2019-11-05

Total Pages: 193

ISBN-13: 3030317455

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Particularly in healthcare fields, there is growing movement away from traditional lecture style course towards active learning and team-based activities to improve learning and build higher level thinking through application of complex problems with a strong foundation of facts and data. Essential Pharmaceutics is suited to this modern teaching style, and is the first book of its kind to provide the resources and skills needed for successful implementation of an active learning pharmaceutics course.This text offers a format that is specifically suited for integration in an active learning, team-based classroom setting. It is ideal for self-learning for the beginning pharmaceutics student, based upon the extensive utilization of figures, tables, and its overview of essential topics in pharmaceutics. Also unique to this text is the integration of case studies based upon modern pharmaceutical products which are designed to reinforce importance pharmaceutical concepts and teach essential skills in literature review and patent searching. Case studies covering all topics covered in the text have been developed by the authors that allow application of the content in the flipped-classroom pharmaceutical course.


Book Synopsis Essential Pharmaceutics by : Ashlee D. Brunaugh

Download or read book Essential Pharmaceutics written by Ashlee D. Brunaugh and published by Springer Nature. This book was released on 2019-11-05 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Particularly in healthcare fields, there is growing movement away from traditional lecture style course towards active learning and team-based activities to improve learning and build higher level thinking through application of complex problems with a strong foundation of facts and data. Essential Pharmaceutics is suited to this modern teaching style, and is the first book of its kind to provide the resources and skills needed for successful implementation of an active learning pharmaceutics course.This text offers a format that is specifically suited for integration in an active learning, team-based classroom setting. It is ideal for self-learning for the beginning pharmaceutics student, based upon the extensive utilization of figures, tables, and its overview of essential topics in pharmaceutics. Also unique to this text is the integration of case studies based upon modern pharmaceutical products which are designed to reinforce importance pharmaceutical concepts and teach essential skills in literature review and patent searching. Case studies covering all topics covered in the text have been developed by the authors that allow application of the content in the flipped-classroom pharmaceutical course.

Formulation Technology

Formulation Technology

Author: Hans Mollet

Publisher: John Wiley & Sons

Published: 2008-11-21

Total Pages: 445

ISBN-13: 3527612939

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Many chemical substances or compounds - organic or inorganic, natural or synthetic - are not used in their pure form. In order for the active ingredient to be most effective or to obtain the ideal delivery form for the market, the actual synthesis and purification steps are followed by formulation to give end products that range from powders, agglomerates, and granules to suspensions, emulsions, microemulsions, microcapsules, instant preparations, liposomes, and tablets. Formulation combines colloid and surface chemistry with chemical process engineering; sometimes it consists of a simple mixing operation, sometimes it requires an entire series of rather complicated engineering procedures such as comminution, dispersion, emulsification, agglomeration or drying. This book covers basic physico-chemical theory as well as its applications in the chemical industry for the production of pharmaceuticals, agrochemicals, pigments and dyes, food, detergents, cosmetics and many other products; it also provides chemists and chemical engineers with the necessary practical tools for the understanding of the structure/ activity relationship.


Book Synopsis Formulation Technology by : Hans Mollet

Download or read book Formulation Technology written by Hans Mollet and published by John Wiley & Sons. This book was released on 2008-11-21 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many chemical substances or compounds - organic or inorganic, natural or synthetic - are not used in their pure form. In order for the active ingredient to be most effective or to obtain the ideal delivery form for the market, the actual synthesis and purification steps are followed by formulation to give end products that range from powders, agglomerates, and granules to suspensions, emulsions, microemulsions, microcapsules, instant preparations, liposomes, and tablets. Formulation combines colloid and surface chemistry with chemical process engineering; sometimes it consists of a simple mixing operation, sometimes it requires an entire series of rather complicated engineering procedures such as comminution, dispersion, emulsification, agglomeration or drying. This book covers basic physico-chemical theory as well as its applications in the chemical industry for the production of pharmaceuticals, agrochemicals, pigments and dyes, food, detergents, cosmetics and many other products; it also provides chemists and chemical engineers with the necessary practical tools for the understanding of the structure/ activity relationship.

Pharmaceutical Suspensions

Pharmaceutical Suspensions

Author: Alok K. Kulshreshtha

Publisher: Springer Science & Business Media

Published: 2009-11-05

Total Pages: 337

ISBN-13: 1441910875

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The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.


Book Synopsis Pharmaceutical Suspensions by : Alok K. Kulshreshtha

Download or read book Pharmaceutical Suspensions written by Alok K. Kulshreshtha and published by Springer Science & Business Media. This book was released on 2009-11-05 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.

Characterization of Nanomaterials in Liquid Disperse Systems

Characterization of Nanomaterials in Liquid Disperse Systems

Author: R. R. Retamal Marín

Publisher: Springer Nature

Published: 2022-04-22

Total Pages: 256

ISBN-13: 3030998819

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This book describes different aspects of characterization and detection of nanomaterials in liquid disperse systems, such as suspensions, emulsions and suspoemulsions. Natural and technical particulate nanomaterials (NMs) are often present in formulations and products consisting of several disperse phases and complex dispersion media. Specific interfacial properties of the particles, their interactions with each other and with the dispersion medium, have to be considered. For example, the interfacial properties determine whether the particles tend to be arranged in aqueous or lipid phases or at their phase boundaries. The interfacial properties are significantly influenced by the adsorption of dissolved species, i.e., they depend on the composition of the dispersion medium. This poses great challenges for the characterization of these nanoparticle systems and requires adequate preparation methods. The nanoparticle measurement techniques aim at a deep physico-chemical understanding of the dispersity state of nanoparticle systems. Since the dispersity state of nanoparticle systems in an application usually does not correspond to their original manufacturing process, the formulation of new or improved product properties is of decisive importance. The characterization of nanoparticles in complex formulations or matrices requires an adequate sample preparation based on an existing or yet to be developed Standard Operating Procedure (SOP). The structure of the SOPs includes the dispersion regulations, which are of essential importance for comparing reproducible results of nanoparticle measurement with respect to comparability and transferability worldwide. The aim is to separate and isolate relevant NMs with knowledge of the interrelationships.


Book Synopsis Characterization of Nanomaterials in Liquid Disperse Systems by : R. R. Retamal Marín

Download or read book Characterization of Nanomaterials in Liquid Disperse Systems written by R. R. Retamal Marín and published by Springer Nature. This book was released on 2022-04-22 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes different aspects of characterization and detection of nanomaterials in liquid disperse systems, such as suspensions, emulsions and suspoemulsions. Natural and technical particulate nanomaterials (NMs) are often present in formulations and products consisting of several disperse phases and complex dispersion media. Specific interfacial properties of the particles, their interactions with each other and with the dispersion medium, have to be considered. For example, the interfacial properties determine whether the particles tend to be arranged in aqueous or lipid phases or at their phase boundaries. The interfacial properties are significantly influenced by the adsorption of dissolved species, i.e., they depend on the composition of the dispersion medium. This poses great challenges for the characterization of these nanoparticle systems and requires adequate preparation methods. The nanoparticle measurement techniques aim at a deep physico-chemical understanding of the dispersity state of nanoparticle systems. Since the dispersity state of nanoparticle systems in an application usually does not correspond to their original manufacturing process, the formulation of new or improved product properties is of decisive importance. The characterization of nanoparticles in complex formulations or matrices requires an adequate sample preparation based on an existing or yet to be developed Standard Operating Procedure (SOP). The structure of the SOPs includes the dispersion regulations, which are of essential importance for comparing reproducible results of nanoparticle measurement with respect to comparability and transferability worldwide. The aim is to separate and isolate relevant NMs with knowledge of the interrelationships.

Pharmaceutical, Cosmetic and Personal Care Formulations

Pharmaceutical, Cosmetic and Personal Care Formulations

Author: Tharwat F. Tadros

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2018-05-22

Total Pages: 362

ISBN-13: 311058798X

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Volume 3 of Formulation Science and Technology is a survey of the applications of formulations in a variety of fields, based on the theories presented in Volumes 1 and 2. It offers in-depth explanations and a wealth of real-world examples for research scientists, universities, and industry practitioners in the fields of Pharmaceuticals, Cosmetics and Personal Care.


Book Synopsis Pharmaceutical, Cosmetic and Personal Care Formulations by : Tharwat F. Tadros

Download or read book Pharmaceutical, Cosmetic and Personal Care Formulations written by Tharwat F. Tadros and published by Walter de Gruyter GmbH & Co KG. This book was released on 2018-05-22 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 3 of Formulation Science and Technology is a survey of the applications of formulations in a variety of fields, based on the theories presented in Volumes 1 and 2. It offers in-depth explanations and a wealth of real-world examples for research scientists, universities, and industry practitioners in the fields of Pharmaceuticals, Cosmetics and Personal Care.

Medical Applications of Colloids

Medical Applications of Colloids

Author: Egon Matijevic

Publisher: Springer Science & Business Media

Published: 2008-12-05

Total Pages: 323

ISBN-13: 0387769218

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The important role of ?nely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Speci?cally, ?ne particles (solid or liquid) in the size range of several nanometers to several micrometers have a tremendous effect on our lives, because they can be bene?cial or detrimental to our well-being. Such particles are present in living bodies as red blood cells or cholesterol crystals in the gall bladder. They are ubiquitous in the environment, where they can cause many diseases, such as asbestosis, silicosis, and black lung disease, but they are also used in diagnostic tests, drug delivery, and numerous other applications. More recently, evidence has become available that drug formulations with active components in a ?nely dispersed state may signi?cantly affect their functionality. Furthermore, with miniaturization of medical instrumentation, the size of the components is necess- ily reduced to colloid or even smaller range. This volume is a collection of several chapters dealing with diverse topics of colloids and surfaces relevant to medical applications. Thus, Siiman describes the use of optical properties of uniform colloidal particles as probes in ?ow cytometry. Giesche focuses on the preparations and properties of exceedingly uniform silica spheres for different uses, such as in chromatography. In modi?ed forms, silica p- ticles with incorporated dyes are employed in diagnostics and those combined with tiny magnetic entities in drug delivery.


Book Synopsis Medical Applications of Colloids by : Egon Matijevic

Download or read book Medical Applications of Colloids written by Egon Matijevic and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The important role of ?nely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Speci?cally, ?ne particles (solid or liquid) in the size range of several nanometers to several micrometers have a tremendous effect on our lives, because they can be bene?cial or detrimental to our well-being. Such particles are present in living bodies as red blood cells or cholesterol crystals in the gall bladder. They are ubiquitous in the environment, where they can cause many diseases, such as asbestosis, silicosis, and black lung disease, but they are also used in diagnostic tests, drug delivery, and numerous other applications. More recently, evidence has become available that drug formulations with active components in a ?nely dispersed state may signi?cantly affect their functionality. Furthermore, with miniaturization of medical instrumentation, the size of the components is necess- ily reduced to colloid or even smaller range. This volume is a collection of several chapters dealing with diverse topics of colloids and surfaces relevant to medical applications. Thus, Siiman describes the use of optical properties of uniform colloidal particles as probes in ?ow cytometry. Giesche focuses on the preparations and properties of exceedingly uniform silica spheres for different uses, such as in chromatography. In modi?ed forms, silica p- ticles with incorporated dyes are employed in diagnostics and those combined with tiny magnetic entities in drug delivery.