Gastric Cancer: the 25-year R-Evolution

Gastric Cancer: the 25-year R-Evolution

Author: Giovanni de Manzoni

Publisher: Springer Nature

Published: 2021-10-15

Total Pages: 276

ISBN-13: 3030731588

DOWNLOAD EBOOK

Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the aim of providing a valuable synopsis for clinicians. The book not only reviews what has changed in the field of gastric cancer over the past quarter century but also offers the reader a glimpse of the future by describing the ongoing surgical and oncological trials which focus on new treatment frontiers such as immunotherapy and target therapy. It also seeks to incorporate the latest discoveries based on molecular classifications. Further, the book reflects the findings and experiences of Italian experts belonging to the GIRCG (Italian Research Group for Gastric Cancer) and will offer an excellent guide for oncological surgeons in their daily practice of caring for patients affected by gastric cancer.


Book Synopsis Gastric Cancer: the 25-year R-Evolution by : Giovanni de Manzoni

Download or read book Gastric Cancer: the 25-year R-Evolution written by Giovanni de Manzoni and published by Springer Nature. This book was released on 2021-10-15 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the aim of providing a valuable synopsis for clinicians. The book not only reviews what has changed in the field of gastric cancer over the past quarter century but also offers the reader a glimpse of the future by describing the ongoing surgical and oncological trials which focus on new treatment frontiers such as immunotherapy and target therapy. It also seeks to incorporate the latest discoveries based on molecular classifications. Further, the book reflects the findings and experiences of Italian experts belonging to the GIRCG (Italian Research Group for Gastric Cancer) and will offer an excellent guide for oncological surgeons in their daily practice of caring for patients affected by gastric cancer.

Gastric Cancer Research Trends

Gastric Cancer Research Trends

Author: Marilyn B. Tompkins

Publisher: Nova Publishers

Published: 2007

Total Pages: 344

ISBN-13: 9781600217258

DOWNLOAD EBOOK

Stomach cancer (also called gastric cancer) is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2 percent (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables.Infection with H. pylori is the main risk factor in about 80 percent or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90 percent of individuals with stomach cancer, with a five year survival rate of 75 percent in those diagnosed in early stages and less than 30 percent of those diagnosed in late stages. This book presents new and important research from around the world.


Book Synopsis Gastric Cancer Research Trends by : Marilyn B. Tompkins

Download or read book Gastric Cancer Research Trends written by Marilyn B. Tompkins and published by Nova Publishers. This book was released on 2007 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stomach cancer (also called gastric cancer) is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2 percent (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables.Infection with H. pylori is the main risk factor in about 80 percent or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90 percent of individuals with stomach cancer, with a five year survival rate of 75 percent in those diagnosed in early stages and less than 30 percent of those diagnosed in late stages. This book presents new and important research from around the world.

Gastric Cancer

Gastric Cancer

Author: Dongfeng Tan

Publisher: Lippincott Williams & Wilkins

Published: 2011

Total Pages: 369

ISBN-13: 1608316173

DOWNLOAD EBOOK

Advances in Surgical Pathology: Gastric Cancer provides a concise, updated review of the pathological characteristics of gastric cancer, with an emphasis on exploring practical issues and recent developments. The book features current and emerging concepts in the field of gastric cancer, a disease whose management requires a multidisciplinary approach in which pathology plays a key role. Its six sections cover the essential histopathology of gastric cancer as well as related topics such as imaging evaluation, molecular diagnosis, and personalized treatment, among other areas of interest. Individual chapters written by international experts in the fields of pathology, gastrointestinal medical oncology, cancer epidemiology, and gastrointestinal radiology, address the fundamental issues surrounding gastric cancer, including its epidemiology, basic diagnostic features, differential diagnoses, pitfalls and complications, and treatments. Endoscopic evaluation and histology correlation are emphasized. The screening, clinical management, and treatment of gastric cancer are summarized in related book sections. Recent findings regarding the roles of immunohistochemistry and molecular testing in the diagnosis, prognosis, and personalized treatment of gastric cancer are also reviewed. The book also includes current knowledge regarding the molecular alteration of gastric cancer carcinogenesis and its impact on patient care.


Book Synopsis Gastric Cancer by : Dongfeng Tan

Download or read book Gastric Cancer written by Dongfeng Tan and published by Lippincott Williams & Wilkins. This book was released on 2011 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Surgical Pathology: Gastric Cancer provides a concise, updated review of the pathological characteristics of gastric cancer, with an emphasis on exploring practical issues and recent developments. The book features current and emerging concepts in the field of gastric cancer, a disease whose management requires a multidisciplinary approach in which pathology plays a key role. Its six sections cover the essential histopathology of gastric cancer as well as related topics such as imaging evaluation, molecular diagnosis, and personalized treatment, among other areas of interest. Individual chapters written by international experts in the fields of pathology, gastrointestinal medical oncology, cancer epidemiology, and gastrointestinal radiology, address the fundamental issues surrounding gastric cancer, including its epidemiology, basic diagnostic features, differential diagnoses, pitfalls and complications, and treatments. Endoscopic evaluation and histology correlation are emphasized. The screening, clinical management, and treatment of gastric cancer are summarized in related book sections. Recent findings regarding the roles of immunohistochemistry and molecular testing in the diagnosis, prognosis, and personalized treatment of gastric cancer are also reviewed. The book also includes current knowledge regarding the molecular alteration of gastric cancer carcinogenesis and its impact on patient care.

Research Focus on Gastric Cancer

Research Focus on Gastric Cancer

Author: Dorothy C. Cardinni

Publisher: Nova Publishers

Published: 2008

Total Pages: 314

ISBN-13: 9781600217265

DOWNLOAD EBOOK

This book presents important leading-edge research on stomach cancer. Stomach cancer (also called "gastric cancer") is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2% (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables. Infection with H. pylori is the main risk factor in about 80% or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90% of individuals with stomach cancer, with a five year survival rate of 75% in those diagnosed in early stages and less than 30% of those diagnosed in late stages.


Book Synopsis Research Focus on Gastric Cancer by : Dorothy C. Cardinni

Download or read book Research Focus on Gastric Cancer written by Dorothy C. Cardinni and published by Nova Publishers. This book was released on 2008 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents important leading-edge research on stomach cancer. Stomach cancer (also called "gastric cancer") is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2% (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables. Infection with H. pylori is the main risk factor in about 80% or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90% of individuals with stomach cancer, with a five year survival rate of 75% in those diagnosed in early stages and less than 30% of those diagnosed in late stages.

The Biology of Gastric Cancers

The Biology of Gastric Cancers

Author: Timothy Wang

Publisher: Springer Science & Business Media

Published: 2009-02-25

Total Pages: 654

ISBN-13: 0387691820

DOWNLOAD EBOOK

As someone who has spent nearly half his life wondering about the relationship between Helicobacter and gastric cancer, I find this textbook on the subject exciting and timely. In fact, I am not aware of any other volume that has been able to distil so much new knowledge into such a comprehensive account of a poorly understood field. Taking my own view, as a scientist placed in the middle of the spectrum between basic science and clinical medicine, I can see that the editors, Jim Fox, Andy Giraud, and Timothy Wang, provide a broad mix of expertise, which ensures that the subject is treated with the right balance. From clinicopathologic observations in humans, to epidemiology, through animal models, to molecular and cell biology, this team has hit the mark for most readers. Fox is a well-known leader in animal models with broad expertise. He pioneered the field with observations on Helicobacter species in animals, from the time when only one spiral gastric bac- rium was known, “Campylobacter pyloridis. ” Fox partners with Wang, whose team recently announced a dramatic advance in the field of carcinogenesis—the obser- tion that bone marrow–derived stem cells participate in the changes that become cancer. To this nice mix has been added Andy Giraud from my own country, who brings to the table some remarkable genetic models of gastric cancer based on alterations in the gp130/stat3-signaling pathway.


Book Synopsis The Biology of Gastric Cancers by : Timothy Wang

Download or read book The Biology of Gastric Cancers written by Timothy Wang and published by Springer Science & Business Media. This book was released on 2009-02-25 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: As someone who has spent nearly half his life wondering about the relationship between Helicobacter and gastric cancer, I find this textbook on the subject exciting and timely. In fact, I am not aware of any other volume that has been able to distil so much new knowledge into such a comprehensive account of a poorly understood field. Taking my own view, as a scientist placed in the middle of the spectrum between basic science and clinical medicine, I can see that the editors, Jim Fox, Andy Giraud, and Timothy Wang, provide a broad mix of expertise, which ensures that the subject is treated with the right balance. From clinicopathologic observations in humans, to epidemiology, through animal models, to molecular and cell biology, this team has hit the mark for most readers. Fox is a well-known leader in animal models with broad expertise. He pioneered the field with observations on Helicobacter species in animals, from the time when only one spiral gastric bac- rium was known, “Campylobacter pyloridis. ” Fox partners with Wang, whose team recently announced a dramatic advance in the field of carcinogenesis—the obser- tion that bone marrow–derived stem cells participate in the changes that become cancer. To this nice mix has been added Andy Giraud from my own country, who brings to the table some remarkable genetic models of gastric cancer based on alterations in the gp130/stat3-signaling pathway.

Gastric Cancer

Gastric Cancer

Author: Harold O. Douglass

Publisher:

Published: 1988

Total Pages: 272

ISBN-13:

DOWNLOAD EBOOK


Book Synopsis Gastric Cancer by : Harold O. Douglass

Download or read book Gastric Cancer written by Harold O. Douglass and published by . This book was released on 1988 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hereditary Gastric and Breast Cancer Syndrome

Hereditary Gastric and Breast Cancer Syndrome

Author: Giovanni Corso

Publisher: Springer Nature

Published: 2023-03-17

Total Pages: 412

ISBN-13: 3031213173

DOWNLOAD EBOOK

In this book the editors and authors provide a comprehensive overview on basic research and clinical aspects of hereditary breast and gastric tumors. In particular, this updated editorial work aims to suggest guidelines for the clinical management of patients with hereditary diffuse gastric and lobular breast cancer. Special attention is given to E-cadherin (CDH1 gene) germline mutations, genetic screening approaches, the underlying molecular mechanisms and pathological and microscopic features. In addition, the book aims to define clinical criteria for genetic screening, and highlights current surgical treatment and clinical approaches for asymptomatic mutation carriers. Other inherited predispositions involving gastric and breast carcinoma are discussed as well. Divided into eight sections, the book starts by providing an epidemiological overview of gastric and breast cancers, followed by a section dealing with new descriptions of genetic pathways in hereditary cancer predispositions. The third section focuses on pathological features of the diseases, in an effort to bridge the gap between discovery and cancer therapy development. Subsequent sections of the book are dedicated to endoscopy and breast imaging, as well as risk-reducing surgeries to curb the risk of developing cancer. The sixth section focuses on the generation of ideas for the identification of targets and novel treatment strategies. Finally, in the seventh section the authors share the story of two patients and their experiences with the diagnosis and treatment of hereditary cancer. This multidisciplinary book brings together multiple disciplines in science and technology; specifically, medicine, surgery and biology. The majority of authors are members of the International Gastric Cancer Linkage Consortium (IGCLC) and of the European Cancer Prevention Organization (EJCPO), with relevant experience in this context. Offering in-depth insights into hereditary cancers, this book represents essential reading for students, researchers, and specialists who want to extend their knowledge on hereditary gastric and breast cancers.


Book Synopsis Hereditary Gastric and Breast Cancer Syndrome by : Giovanni Corso

Download or read book Hereditary Gastric and Breast Cancer Syndrome written by Giovanni Corso and published by Springer Nature. This book was released on 2023-03-17 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the editors and authors provide a comprehensive overview on basic research and clinical aspects of hereditary breast and gastric tumors. In particular, this updated editorial work aims to suggest guidelines for the clinical management of patients with hereditary diffuse gastric and lobular breast cancer. Special attention is given to E-cadherin (CDH1 gene) germline mutations, genetic screening approaches, the underlying molecular mechanisms and pathological and microscopic features. In addition, the book aims to define clinical criteria for genetic screening, and highlights current surgical treatment and clinical approaches for asymptomatic mutation carriers. Other inherited predispositions involving gastric and breast carcinoma are discussed as well. Divided into eight sections, the book starts by providing an epidemiological overview of gastric and breast cancers, followed by a section dealing with new descriptions of genetic pathways in hereditary cancer predispositions. The third section focuses on pathological features of the diseases, in an effort to bridge the gap between discovery and cancer therapy development. Subsequent sections of the book are dedicated to endoscopy and breast imaging, as well as risk-reducing surgeries to curb the risk of developing cancer. The sixth section focuses on the generation of ideas for the identification of targets and novel treatment strategies. Finally, in the seventh section the authors share the story of two patients and their experiences with the diagnosis and treatment of hereditary cancer. This multidisciplinary book brings together multiple disciplines in science and technology; specifically, medicine, surgery and biology. The majority of authors are members of the International Gastric Cancer Linkage Consortium (IGCLC) and of the European Cancer Prevention Organization (EJCPO), with relevant experience in this context. Offering in-depth insights into hereditary cancers, this book represents essential reading for students, researchers, and specialists who want to extend their knowledge on hereditary gastric and breast cancers.

Management of Gastric Cancer

Management of Gastric Cancer

Author: Paul H. Sugarbaker

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 405

ISBN-13: 1461538823

DOWNLOAD EBOOK

Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.


Book Synopsis Management of Gastric Cancer by : Paul H. Sugarbaker

Download or read book Management of Gastric Cancer written by Paul H. Sugarbaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.

Staging Laparoscopy

Staging Laparoscopy

Author: P. Hohenberger

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 206

ISBN-13: 3642562906

DOWNLOAD EBOOK

Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.


Book Synopsis Staging Laparoscopy by : P. Hohenberger

Download or read book Staging Laparoscopy written by P. Hohenberger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

Laparoscopic Gastrectomy for Gastric Cancer

Laparoscopic Gastrectomy for Gastric Cancer

Author: Chang-Ming Huang

Publisher: Springer

Published: 2015-05-05

Total Pages: 357

ISBN-13: 9401798737

DOWNLOAD EBOOK

This book presents surgical techniques and detailed illustrations of laparoscopic gastrectomy for gastric cancer, focusing on effective, concise steps and techniques. It describes in detail the perigastric anatomy, and the incidences of each anatomical structure are analyzed statistically. It also discusses lessons learned and best practices in the management of gastric cancer patients, and includes video captures of precise operational techniques -essential resources for gastrointestinal laparoscopic surgeons. Given its close connection to clinical practice, it offers a valuable reference work for general surgeons and residents.​


Book Synopsis Laparoscopic Gastrectomy for Gastric Cancer by : Chang-Ming Huang

Download or read book Laparoscopic Gastrectomy for Gastric Cancer written by Chang-Ming Huang and published by Springer. This book was released on 2015-05-05 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents surgical techniques and detailed illustrations of laparoscopic gastrectomy for gastric cancer, focusing on effective, concise steps and techniques. It describes in detail the perigastric anatomy, and the incidences of each anatomical structure are analyzed statistically. It also discusses lessons learned and best practices in the management of gastric cancer patients, and includes video captures of precise operational techniques -essential resources for gastrointestinal laparoscopic surgeons. Given its close connection to clinical practice, it offers a valuable reference work for general surgeons and residents.​