Gastrointestinal Pathology: Common Questions and Diagnostic Dilemmas, An Issue of Surgical Pathology Clinics, E-Book

Gastrointestinal Pathology: Common Questions and Diagnostic Dilemmas, An Issue of Surgical Pathology Clinics, E-Book

Author: Rhonda K. Yantiss

Publisher: Elsevier Health Sciences

Published: 2017-11-13

Total Pages:

ISBN-13: 0323553036

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This issue of Surgical Pathology Clinics, edited by Rhonda K. Yantiss, will focus on Gastrointestinal Pathology: Common Questions and Diagnostic Dilemmas. Topics in this issue include, but are not limited to: Other forms of esophagitis; Diagnosis and management of Barrett-related neoplasia in the modern era; Patterns of gastric injury; Practical approach to the flat duodenal biopsy specimen; Chronic colitis in biopsy samples; Mucosal biopsy following bone marrow transplantation; The many faces of medication-related injury in the GI tract; The differential diagnosis of acute colitis: Clues to a specific diagnosis; Problematic colorectal polyps; Persistent problems in colorectal cancer reporting; Emerging concepts in gastric neoplasia; Immunohistochemistry pitfalls; Molecular testing in the modern era, and Lymphoproliferative diseases of the gut.


Book Synopsis Gastrointestinal Pathology: Common Questions and Diagnostic Dilemmas, An Issue of Surgical Pathology Clinics, E-Book by : Rhonda K. Yantiss

Download or read book Gastrointestinal Pathology: Common Questions and Diagnostic Dilemmas, An Issue of Surgical Pathology Clinics, E-Book written by Rhonda K. Yantiss and published by Elsevier Health Sciences. This book was released on 2017-11-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Pathology Clinics, edited by Rhonda K. Yantiss, will focus on Gastrointestinal Pathology: Common Questions and Diagnostic Dilemmas. Topics in this issue include, but are not limited to: Other forms of esophagitis; Diagnosis and management of Barrett-related neoplasia in the modern era; Patterns of gastric injury; Practical approach to the flat duodenal biopsy specimen; Chronic colitis in biopsy samples; Mucosal biopsy following bone marrow transplantation; The many faces of medication-related injury in the GI tract; The differential diagnosis of acute colitis: Clues to a specific diagnosis; Problematic colorectal polyps; Persistent problems in colorectal cancer reporting; Emerging concepts in gastric neoplasia; Immunohistochemistry pitfalls; Molecular testing in the modern era, and Lymphoproliferative diseases of the gut.


Oncological Surgical Pathology

Oncological Surgical Pathology

Author: Cesar A. Moran

Publisher: Springer Nature

Published: 2020-01-29

Total Pages: 2209

ISBN-13: 3319966812

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This text provides the necessary tools and up-to-date information on the morphological approach and most current use of ancillary techniques in the diagnosis and treatment of malignant tumors. The work is divided by sub specialty areas so that the reader can easily obtain the information desired. Features of histopathological lesions are presented in each area, as well as an up-to-date use of the different immunohistochemical stains and molecular biology features, when applicable, which are commonly used to determine treatment modalities. All sub specialty sections are written by sub specialty pathologists with experience in tumor pathology and who work in a cancer center. Each chapter is richly illustrated and properly referenced. Oncological Surgical Pathology will be of use not only for pathologists (including pathology residents and fellows), but also for oncological surgeons, oncologists and interventional radiologists.


Book Synopsis Oncological Surgical Pathology by : Cesar A. Moran

Download or read book Oncological Surgical Pathology written by Cesar A. Moran and published by Springer Nature. This book was released on 2020-01-29 with total page 2209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides the necessary tools and up-to-date information on the morphological approach and most current use of ancillary techniques in the diagnosis and treatment of malignant tumors. The work is divided by sub specialty areas so that the reader can easily obtain the information desired. Features of histopathological lesions are presented in each area, as well as an up-to-date use of the different immunohistochemical stains and molecular biology features, when applicable, which are commonly used to determine treatment modalities. All sub specialty sections are written by sub specialty pathologists with experience in tumor pathology and who work in a cancer center. Each chapter is richly illustrated and properly referenced. Oncological Surgical Pathology will be of use not only for pathologists (including pathology residents and fellows), but also for oncological surgeons, oncologists and interventional radiologists.


Gastrointestinal Pathology, An Issue of Surgical Pathology Clinics, E-Book

Gastrointestinal Pathology, An Issue of Surgical Pathology Clinics, E-Book

Author: Rondell P. Graham

Publisher: Elsevier Health Sciences

Published: 2023-10-23

Total Pages: 292

ISBN-13: 0443183171

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In this issue of Surgical Pathology Clinics, guest editor Dr. Rondell P. Graham brings his considerable expertise to the topic of Gastrointestinal Pathology. The first half of this issue answers questions from the general pathologist about what new technologies and techniques can confidently be incorporated into daily practice. The second half addresses longstanding riddles and recurring tests, making this issue an excellent resource for practicing pathologists facing new and continuing challenges in GI pathology. Contains 11 practice-oriented topics including artificial intelligence-enabled gastric cancer interpretations: are we there yet?; non-conventional dysplasia in inflammatory bowel disease; a practical approach to small round blue cell tumors involving the GI tract and abdomen infectious disease pathology of the GI tract: diagnosing the challenging cases; and more. Provides in-depth clinical reviews on gastrointestinal pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Book Synopsis Gastrointestinal Pathology, An Issue of Surgical Pathology Clinics, E-Book by : Rondell P. Graham

Download or read book Gastrointestinal Pathology, An Issue of Surgical Pathology Clinics, E-Book written by Rondell P. Graham and published by Elsevier Health Sciences. This book was released on 2023-10-23 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Surgical Pathology Clinics, guest editor Dr. Rondell P. Graham brings his considerable expertise to the topic of Gastrointestinal Pathology. The first half of this issue answers questions from the general pathologist about what new technologies and techniques can confidently be incorporated into daily practice. The second half addresses longstanding riddles and recurring tests, making this issue an excellent resource for practicing pathologists facing new and continuing challenges in GI pathology. Contains 11 practice-oriented topics including artificial intelligence-enabled gastric cancer interpretations: are we there yet?; non-conventional dysplasia in inflammatory bowel disease; a practical approach to small round blue cell tumors involving the GI tract and abdomen infectious disease pathology of the GI tract: diagnosing the challenging cases; and more. Provides in-depth clinical reviews on gastrointestinal pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics: Volume 16-4

Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics: Volume 16-4

Author: Rondell P. Graham

Publisher: Clinics: Surgery

Published: 2023-12-28

Total Pages: 0

ISBN-13: 9780443183164

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In this issue of Surgical Pathology Clinics, guest editor Dr. Rondell P. Graham brings his considerable expertise to the topic of Gastrointestinal Pathology. The first half of this issue answers questions from the general pathologist about what new technologies and techniques can confidently be incorporated into daily practice. The second half addresses longstanding riddles and recurring tests, making this issue an excellent resource for practicing pathologists facing new and continuing challenges in GI pathology. Contains 11 practice-oriented topics including artificial intelligence-enabled gastric cancer interpretations: are we there yet?; non-conventional dysplasia in inflammatory bowel disease; a practical approach to small round blue cell tumors involving the GI tract and abdomen infectious disease pathology of the GI tract: diagnosing the challenging cases; and more. Provides in-depth clinical reviews on gastrointestinal pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Book Synopsis Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics: Volume 16-4 by : Rondell P. Graham

Download or read book Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics: Volume 16-4 written by Rondell P. Graham and published by Clinics: Surgery. This book was released on 2023-12-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Surgical Pathology Clinics, guest editor Dr. Rondell P. Graham brings his considerable expertise to the topic of Gastrointestinal Pathology. The first half of this issue answers questions from the general pathologist about what new technologies and techniques can confidently be incorporated into daily practice. The second half addresses longstanding riddles and recurring tests, making this issue an excellent resource for practicing pathologists facing new and continuing challenges in GI pathology. Contains 11 practice-oriented topics including artificial intelligence-enabled gastric cancer interpretations: are we there yet?; non-conventional dysplasia in inflammatory bowel disease; a practical approach to small round blue cell tumors involving the GI tract and abdomen infectious disease pathology of the GI tract: diagnosing the challenging cases; and more. Provides in-depth clinical reviews on gastrointestinal pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Practical Gastrointestinal Pathology

Practical Gastrointestinal Pathology

Author: Hanlin L. Wang

Publisher: Springer Nature

Published: 2020-12-05

Total Pages: 581

ISBN-13: 3030512681

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This book addresses practical issues that reflect the current landscape of GI pathology practice and is organized in such a way that fits the fast-pacing daily life of practicing pathologists. It contains more than 540 questions that address difficult, prevailing and controversial issues in GI pathology that are frequently encountered in daily practice and consult service. For most questions, answers are straightforward with ample literature support. However, true diagnostic controversies and clinical dilemma cannot be easily resolved with current knowledge and available information. To such challenges, an expert approach regarding how to synthesize complicated topics and clearly communicate the thinking process is valuable to readers and can help guide clinicians making optimal treatment plans for their patients. The latter types of answers are highly enriched throughout the book. Distinct from other existing GI pathology textbooks, this book is primarily organized according to disease entities and pathological processes instead of specific organs and anatomic locations. Guided by chapter titles and listed questions, readers should be able to look up a disease or a pathological feature and find the most important and relevant diagnostic criteria and pertinent differential diagnoses. Written by experts in the field, Practical Gastrointestinal Pathology provides easy and quick access to concise, evidence-based and up-to-date information to aid accurate diagnosis and serves as a useful resource for practicing pathologists, pathology trainees and GI clinicians as well as allied health professionals who frequently deal with GI pathology.


Book Synopsis Practical Gastrointestinal Pathology by : Hanlin L. Wang

Download or read book Practical Gastrointestinal Pathology written by Hanlin L. Wang and published by Springer Nature. This book was released on 2020-12-05 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses practical issues that reflect the current landscape of GI pathology practice and is organized in such a way that fits the fast-pacing daily life of practicing pathologists. It contains more than 540 questions that address difficult, prevailing and controversial issues in GI pathology that are frequently encountered in daily practice and consult service. For most questions, answers are straightforward with ample literature support. However, true diagnostic controversies and clinical dilemma cannot be easily resolved with current knowledge and available information. To such challenges, an expert approach regarding how to synthesize complicated topics and clearly communicate the thinking process is valuable to readers and can help guide clinicians making optimal treatment plans for their patients. The latter types of answers are highly enriched throughout the book. Distinct from other existing GI pathology textbooks, this book is primarily organized according to disease entities and pathological processes instead of specific organs and anatomic locations. Guided by chapter titles and listed questions, readers should be able to look up a disease or a pathological feature and find the most important and relevant diagnostic criteria and pertinent differential diagnoses. Written by experts in the field, Practical Gastrointestinal Pathology provides easy and quick access to concise, evidence-based and up-to-date information to aid accurate diagnosis and serves as a useful resource for practicing pathologists, pathology trainees and GI clinicians as well as allied health professionals who frequently deal with GI pathology.


Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics, Volume 13-3

Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics, Volume 13-3

Author: Raul S. Gonzalez

Publisher: Elsevier

Published: 2020-09-28

Total Pages: 240

ISBN-13: 9780323758802

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This issue of Surgical Pathology Clinics, guest edited by Dr. Raul Gonzalez, will cover key topics in Gastrointestinal Pathology. This issue is one of four selected each year by our series consulting editor, Dr. Jason L. Hornick. Topics discussed in this issue will include: Grossing of Gastrointestinal Specimens: Best Practices and Current Controversies, Subspecialty Signout and Interobserver Variability in Gastrointestinal Pathology, Diagnosis and Management of Gastrointestinal Neuroendocrine Neoplasms, Daily Dilemmas in Pediatric Gastrointestinal Pathology, Upper Gastrointestinal Tract Manifestations of Inflammatory Bowel Disease, Gastric Polyps, Approaches to Biopsy and Resection Specimens of the Ampulla, Updates in Appendix Pathology, HER2 in Colorectal Carcinoma, Histology of Colorectal Carcinoma: Proven and Purported Prognostic Factors, Diagnoses and Difficulties in Mesenteric Pathology, Advances and Annoyances in Anus Pathology, among others.


Book Synopsis Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics, Volume 13-3 by : Raul S. Gonzalez

Download or read book Gastrointestinal Pathology, an Issue of Surgical Pathology Clinics, Volume 13-3 written by Raul S. Gonzalez and published by Elsevier. This book was released on 2020-09-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Pathology Clinics, guest edited by Dr. Raul Gonzalez, will cover key topics in Gastrointestinal Pathology. This issue is one of four selected each year by our series consulting editor, Dr. Jason L. Hornick. Topics discussed in this issue will include: Grossing of Gastrointestinal Specimens: Best Practices and Current Controversies, Subspecialty Signout and Interobserver Variability in Gastrointestinal Pathology, Diagnosis and Management of Gastrointestinal Neuroendocrine Neoplasms, Daily Dilemmas in Pediatric Gastrointestinal Pathology, Upper Gastrointestinal Tract Manifestations of Inflammatory Bowel Disease, Gastric Polyps, Approaches to Biopsy and Resection Specimens of the Ampulla, Updates in Appendix Pathology, HER2 in Colorectal Carcinoma, Histology of Colorectal Carcinoma: Proven and Purported Prognostic Factors, Diagnoses and Difficulties in Mesenteric Pathology, Advances and Annoyances in Anus Pathology, among others.


Surgical Pathology of the Gastrointestinal System

Surgical Pathology of the Gastrointestinal System

Author: Prasenjit Das

Publisher: Springer Nature

Published: 2022-03-07

Total Pages: 1037

ISBN-13: 9811663955

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This two-volume textbook provides a comprehensive review of both adult and pediatric gastrointestinal, hepatobiliary and pancreatic pathology. The 1st volume is dedicated to gastrointestinal tract pathology. The second volume of this book covers liver, biliary system, and pancreatic pathology. This book covers each aspect of gastrointestinal tract pathology in detail, including clinical presentation, endoscopic appearance, disease pathogenesis, gross and microscopic details of each lesion. Ancillary diagnostic methods, molecular subtypes, and prognostic workup have been detailed adequately. The book also covers diseases relevant to South-East Asia, in addition to diseases prevalent worldwide. It contains 24 chapters, categorized into four sections. Section I covers the general aspects of gastrointestinal pathology including normal anatomy of the gastrointestinal tract, endoscopic details relevant for gastrointestinal pathologists and histopathologists, grossing techniques, utility of and details of ancillary tests needed; section II covers all benign diseases in different anatomical parts of the gastrointestinal tract; section III covers preneoplastic lesions and malignancies of the gastrointestinal tract, including a separate chapter on updated molecular classifications of gastrointestinal tract tumors arising from different segments; section IV includes a unique chapter on setting up a gastrointestinal pathology laboratory. This textbook has been written and edited by experts in the field with proven academic and research excellence and include curated contents to provide lucid and updated information to the readers. The book features more than 800 photographs, line diagrams, endoscopic and radiology pictures, gross and microscopic images. It includes 'Chapter Summary' at the end of each chapter and ‘Learning Tips’ summarized after each major segment that helps the readers to reinforce the knowledge gained from each chapter. Chapters also contain case studies and/ or multiple-choice questions to enable readers to self-assess and learn from the explanations added. The textbook includes many unique chapters. It also covers cytological details and techniques relevant to gastrointestinal pathology. This comprehensive review of gastrointestinal pathology is a valuable resource for the faculties, gastrointestinal pathologists, cytologists, histopathologists, practicing pathologists, gastroenterologists, gastrointestinal surgeons, pathology fellows, postgraduates, clinical gastrointestinal fellows, and researchers in related fields.


Book Synopsis Surgical Pathology of the Gastrointestinal System by : Prasenjit Das

Download or read book Surgical Pathology of the Gastrointestinal System written by Prasenjit Das and published by Springer Nature. This book was released on 2022-03-07 with total page 1037 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume textbook provides a comprehensive review of both adult and pediatric gastrointestinal, hepatobiliary and pancreatic pathology. The 1st volume is dedicated to gastrointestinal tract pathology. The second volume of this book covers liver, biliary system, and pancreatic pathology. This book covers each aspect of gastrointestinal tract pathology in detail, including clinical presentation, endoscopic appearance, disease pathogenesis, gross and microscopic details of each lesion. Ancillary diagnostic methods, molecular subtypes, and prognostic workup have been detailed adequately. The book also covers diseases relevant to South-East Asia, in addition to diseases prevalent worldwide. It contains 24 chapters, categorized into four sections. Section I covers the general aspects of gastrointestinal pathology including normal anatomy of the gastrointestinal tract, endoscopic details relevant for gastrointestinal pathologists and histopathologists, grossing techniques, utility of and details of ancillary tests needed; section II covers all benign diseases in different anatomical parts of the gastrointestinal tract; section III covers preneoplastic lesions and malignancies of the gastrointestinal tract, including a separate chapter on updated molecular classifications of gastrointestinal tract tumors arising from different segments; section IV includes a unique chapter on setting up a gastrointestinal pathology laboratory. This textbook has been written and edited by experts in the field with proven academic and research excellence and include curated contents to provide lucid and updated information to the readers. The book features more than 800 photographs, line diagrams, endoscopic and radiology pictures, gross and microscopic images. It includes 'Chapter Summary' at the end of each chapter and ‘Learning Tips’ summarized after each major segment that helps the readers to reinforce the knowledge gained from each chapter. Chapters also contain case studies and/ or multiple-choice questions to enable readers to self-assess and learn from the explanations added. The textbook includes many unique chapters. It also covers cytological details and techniques relevant to gastrointestinal pathology. This comprehensive review of gastrointestinal pathology is a valuable resource for the faculties, gastrointestinal pathologists, cytologists, histopathologists, practicing pathologists, gastroenterologists, gastrointestinal surgeons, pathology fellows, postgraduates, clinical gastrointestinal fellows, and researchers in related fields.


Ehlers-Danlos Syndrome: A Multidisciplinary Approach

Ehlers-Danlos Syndrome: A Multidisciplinary Approach

Author: J.W.G. Jacobs

Publisher: IOS Press

Published: 2018-08-14

Total Pages: 370

ISBN-13: 1614998787

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Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.


Book Synopsis Ehlers-Danlos Syndrome: A Multidisciplinary Approach by : J.W.G. Jacobs

Download or read book Ehlers-Danlos Syndrome: A Multidisciplinary Approach written by J.W.G. Jacobs and published by IOS Press. This book was released on 2018-08-14 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized hypermobility has been known since ancient times, and a clinical description of Ehlers-Danlos syndrome (EDS) is said to have first been recorded by Hippocrates in 400 BC. Hypermobility syndromes occur frequently, but the wide spectrum of possible symptoms, coupled with a relative lack of awareness and recognition, are the reason that they are frequently not recognized, or remain undiagnosed. This book is an international, multidisciplinary guide to hypermobility syndromes, and EDS in particular. It aims to create better awareness of hypermobility syndromes among health professionals, including medical specialists, and to be a guide to the management of such syndromes for patients and practitioners. It is intended for use in daily clinical practice rather than as a reference book for research or the latest developments, and has been written to be understandable for any healthcare worker or educated patient without compromise to the scientific content. The book is organized as follows: chapters on classifications and genetics are followed by chapters on individual types, organ (system) manifestations and complications, and finally ethics and therapeutic strategies, with an appendix on surgery and the precautions which should attend it. A special effort has been made to take account of the perspective of the patient; two of the editors have EDS. The book will be of interest to patients with hypermobility syndromes and their families, as well as to all those healthcare practitioners who may encounter such syndromes in the course of their work.


Fine Needle Aspiration Cytology

Fine Needle Aspiration Cytology

Author: Gabrijela Kocjan

Publisher: Springer Science & Business Media

Published: 2006-02-23

Total Pages: 243

ISBN-13: 3540314121

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Histopathologists all over the world have to report cytopathology during the course of their work and it is then that they find themselves facing diagnostic dilemmas. This practical, well-illustrated book, explicitly dedicated to this readership will serve their needs and meets their requirements in daily practice.


Book Synopsis Fine Needle Aspiration Cytology by : Gabrijela Kocjan

Download or read book Fine Needle Aspiration Cytology written by Gabrijela Kocjan and published by Springer Science & Business Media. This book was released on 2006-02-23 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histopathologists all over the world have to report cytopathology during the course of their work and it is then that they find themselves facing diagnostic dilemmas. This practical, well-illustrated book, explicitly dedicated to this readership will serve their needs and meets their requirements in daily practice.


Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-09-28

Total Pages: 483

ISBN-13: 0309459575

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Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.


Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.