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Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Nirali N. Shah

Publisher: Elsevier Health Sciences

Published: 2022-07-19

Total Pages: 273

ISBN-13: 0323987761

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In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Book Synopsis Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book by : Nirali N. Shah

Download or read book Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book written by Nirali N. Shah and published by Elsevier Health Sciences. This book was released on 2022-07-19 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America

Author: Sung-Yun Pai, MD

Publisher: Elsevier

Published: 2022-08-28

Total Pages: 240

ISBN-13: 9780323987752

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Book Synopsis Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America by : Sung-Yun Pai, MD

Download or read book Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America written by Sung-Yun Pai, MD and published by Elsevier. This book was released on 2022-08-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Daniel E. Bauer

Publisher: Elsevier Health Sciences

Published: 2017-09-27

Total Pages:

ISBN-13: 0323546692

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This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

Book Synopsis Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book by : Daniel E. Bauer

Download or read book Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book written by Daniel E. Bauer and published by Elsevier Health Sciences. This book was released on 2017-09-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America

Author: Rachael Grace

Publisher: Elsevier Health Sciences

Published: 2019-05-05

Total Pages:

ISBN-13: 0323673341

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This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.

Book Synopsis Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America by : Rachael Grace

Download or read book Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America written by Rachael Grace and published by Elsevier Health Sciences. This book was released on 2019-05-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.

An Update on Pediatric Oncology and Hematology , an Issue of Hematology/Oncology Clinics of North America

Author: Max J. Coppes

Publisher: Clinics: Internal Medicine

Published: 2010

Total Pages: 0

ISBN-13: 9781437722024

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This issue highlights some of the exciting new developments in pediatric oncology and hematology. Three articles are devoted to pediatric leukemia, which remains the most common form of pediatric cancer. Specifically, articles address ALL, AML, and leukemia in patients with Down syndrome. Other articles that address pediatric oncology include CNS tumors and neuroblastoma as well as advances in cancer immunotherapy. A very interesting article addresses the challenges experienced by adults who survived a childhood cancer. The hematology articles in this issue cover aspects that most clinicians see on a regular basis-sickle cell disease, thalassemia, and hemophilia, and ITP.

Book Synopsis An Update on Pediatric Oncology and Hematology , an Issue of Hematology/Oncology Clinics of North America by : Max J. Coppes

Download or read book An Update on Pediatric Oncology and Hematology , an Issue of Hematology/Oncology Clinics of North America written by Max J. Coppes and published by Clinics: Internal Medicine. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue highlights some of the exciting new developments in pediatric oncology and hematology. Three articles are devoted to pediatric leukemia, which remains the most common form of pediatric cancer. Specifically, articles address ALL, AML, and leukemia in patients with Down syndrome. Other articles that address pediatric oncology include CNS tumors and neuroblastoma as well as advances in cancer immunotherapy. A very interesting article addresses the challenges experienced by adults who survived a childhood cancer. The hematology articles in this issue cover aspects that most clinicians see on a regular basis-sickle cell disease, thalassemia, and hemophilia, and ITP.

Neutropenia, An Issue of Hematology/Oncology Clinics of North America

Author: Christoph Klein

Publisher: Elsevier Health Sciences

Published: 2013-02-28

Total Pages: 272

ISBN-13: 1455771872

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This issue of Hematology/Oncology Clinics is guest edited by Dr. Christoph Klein and focuses on the topic of Neutropenia. Article titles include: Homeostasis and migration of neutrophil granulocytes,Granulocyte-colony Stimulating Factor (G-CSF) receptor signaling,New Granulocyte-colony Stimulating Factor (G-CSF) Receptor Signaling Pathways ,Neutrophil elastase (ELANE) – Genetics and Pathophysiology,Autosomal recessive variants of Severe congenital neutropenia (SCN),Leukocyte Adhesion Deficiency (LAD), and Genotype-phenotype correlations in Severe congenital neutropenia (SCN).

Book Synopsis Neutropenia, An Issue of Hematology/Oncology Clinics of North America by : Christoph Klein

Download or read book Neutropenia, An Issue of Hematology/Oncology Clinics of North America written by Christoph Klein and published by Elsevier Health Sciences. This book was released on 2013-02-28 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics is guest edited by Dr. Christoph Klein and focuses on the topic of Neutropenia. Article titles include: Homeostasis and migration of neutrophil granulocytes,Granulocyte-colony Stimulating Factor (G-CSF) receptor signaling,New Granulocyte-colony Stimulating Factor (G-CSF) Receptor Signaling Pathways ,Neutrophil elastase (ELANE) – Genetics and Pathophysiology,Autosomal recessive variants of Severe congenital neutropenia (SCN),Leukocyte Adhesion Deficiency (LAD), and Genotype-phenotype correlations in Severe congenital neutropenia (SCN).

Blastic Plasmacytoid Dendritic Cell Neoplasm An Issue of Hematology/Oncology Clinics of North America

Author: Andrew A. Lane

Publisher: Elsevier Health Sciences

Published: 2020-06-02

Total Pages: 161

ISBN-13: 0323722652

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This issue of Hematology/Oncology Clinics, guest edited by Andrew A. Lane, will cover Blastic Plasmacytoid Dendritic Cell Neoplasm. This issue is one of six selected each year by our series consulting editors, Dr. George P. Canellos and Dr. Edward J. Benz. Topics discussed in this issue include: Clinical Presentation and Pathology, Molecular Features of Blastic Plasmacytoid Dendritic Cell Neoplasm: DNA mutations and epigenetics, Cytogenetics of Blastic Plasmacytoid Dendritic Cell Neoplasm, Blastic Plasmacytoid Dendritic Cell Neoplasm Chemotherapy, CD123 and Leukemia Stem Cells, Tagraxofusp for Blastic Plasmacytoid Dendritic Cell Neoplasm, Immune Therapies Targeting CD123 in Blastic Plasmacytoid Dendritic Cell Neoplasm, Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm, Blastic Plasmacytoid Dendritic Cell Neoplasm in Children, European Perspective, Stem Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm, and Social Media in Blastic Plasmacytoid Dendritic Cell Neoplasm and Other Rare Diseases.

Book Synopsis Blastic Plasmacytoid Dendritic Cell Neoplasm An Issue of Hematology/Oncology Clinics of North America by : Andrew A. Lane

Download or read book Blastic Plasmacytoid Dendritic Cell Neoplasm An Issue of Hematology/Oncology Clinics of North America written by Andrew A. Lane and published by Elsevier Health Sciences. This book was released on 2020-06-02 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, guest edited by Andrew A. Lane, will cover Blastic Plasmacytoid Dendritic Cell Neoplasm. This issue is one of six selected each year by our series consulting editors, Dr. George P. Canellos and Dr. Edward J. Benz. Topics discussed in this issue include: Clinical Presentation and Pathology, Molecular Features of Blastic Plasmacytoid Dendritic Cell Neoplasm: DNA mutations and epigenetics, Cytogenetics of Blastic Plasmacytoid Dendritic Cell Neoplasm, Blastic Plasmacytoid Dendritic Cell Neoplasm Chemotherapy, CD123 and Leukemia Stem Cells, Tagraxofusp for Blastic Plasmacytoid Dendritic Cell Neoplasm, Immune Therapies Targeting CD123 in Blastic Plasmacytoid Dendritic Cell Neoplasm, Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm, Blastic Plasmacytoid Dendritic Cell Neoplasm in Children, European Perspective, Stem Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm, and Social Media in Blastic Plasmacytoid Dendritic Cell Neoplasm and Other Rare Diseases.

Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Sophie Lanzkron

Publisher: Elsevier Health Sciences

Published: 2022-11-20

Total Pages: 289

ISBN-13: 0323986641

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In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Book Synopsis Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book by : Sophie Lanzkron

Download or read book Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book written by Sophie Lanzkron and published by Elsevier Health Sciences. This book was released on 2022-11-20 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Pediatric Hematology, An Issue of Pediatric Clinics

Author: Catherine S. Manno

Publisher: Elsevier Health Sciences

Published: 2013-12-28

Total Pages: 345

ISBN-13: 0323261191

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This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician’s understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients – resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.

Book Synopsis Pediatric Hematology, An Issue of Pediatric Clinics by : Catherine S. Manno

Download or read book Pediatric Hematology, An Issue of Pediatric Clinics written by Catherine S. Manno and published by Elsevier Health Sciences. This book was released on 2013-12-28 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician’s understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients – resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.

Colorectal Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Kimmie Ng

Publisher: Elsevier Health Sciences

Published: 2022-05-30

Total Pages: 249

ISBN-13: 0323850022

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In this issue of Hematology/Oncology Clinics, guest editors Drs. Kimmie Ng and Benjamin L. Schlechter bring their considerable expertise to the topic of Colorectal Cancer. Despite tremendous progress in the management of this disease, many questions and controversies remain regarding screening, adjuvant therapy for resected colon cancers, targeted therapies and immunotherapy for patients with advanced disease, surgical management, and more. In this issue, top experts in the field address provide clinicians with the tools to individualize management and optimize care for this growing patient population. Contains 13 relevant, practice-oriented topics including screening for colorectal cancer; hereditary colorectal cancer; disparities in colorectal cancer; microbiome in colorectal cancer; impact of diet and exercise on colorectal cancer; colorectal cancer in younger adults; and more. Provides in-depth clinical reviews on colorectal cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Book Synopsis Colorectal Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book by : Kimmie Ng

Download or read book Colorectal Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book written by Kimmie Ng and published by Elsevier Health Sciences. This book was released on 2022-05-30 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Kimmie Ng and Benjamin L. Schlechter bring their considerable expertise to the topic of Colorectal Cancer. Despite tremendous progress in the management of this disease, many questions and controversies remain regarding screening, adjuvant therapy for resected colon cancers, targeted therapies and immunotherapy for patients with advanced disease, surgical management, and more. In this issue, top experts in the field address provide clinicians with the tools to individualize management and optimize care for this growing patient population. Contains 13 relevant, practice-oriented topics including screening for colorectal cancer; hereditary colorectal cancer; disparities in colorectal cancer; microbiome in colorectal cancer; impact of diet and exercise on colorectal cancer; colorectal cancer in younger adults; and more. Provides in-depth clinical reviews on colorectal cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.