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This book has been written in response to the many physicians and scien tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.
Book Synopsis Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine by : Johnny Huard
Download or read book Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine written by Johnny Huard and published by Springer Science & Business Media. This book was released on 2013-03-11 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been written in response to the many physicians and scien tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.
This book has been written in response to the many physicians and scien- tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.
Book Synopsis Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine by : Johnny Huard
Download or read book Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine written by Johnny Huard and published by . This book was released on 2000 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been written in response to the many physicians and scien- tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.
This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.
Book Synopsis Orthobiologics by : Giuseppe Filardo
Download or read book Orthobiologics written by Giuseppe Filardo and published by Springer Nature. This book was released on 2021-12-02 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.
"Gene Therapy for Cartilage and Bone Tissue Engineering" outlines the tissue engineering and possible applications of gene therapy in the field of biomedical engineering as well as basic principles of gene therapy, vectors and gene delivery, specifically for cartilage and bone engineering. It is intended for tissue engineers, cell therapists, regenerative medicine scientists and engineers, gene therapist and virologists. Dr. Yu-Chen Hu is a Distinguished Professor at the Department of Chemical Engineering, National Tsing Hua University and has received the Outstanding Research Award (National Science Council), Asia Research Award (Society of Chemical Engineers, Japan) and Professor Tsai-Teh Lai Award (Taiwan Institute of Chemical Engineers). He is also a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and a member of the Tissue Engineering International & Regenerative Medicine Society (TERMIS)-Asia Pacific Council.
Book Synopsis Gene Therapy for Cartilage and Bone Tissue Engineering by : Yu-Chen Hu
Download or read book Gene Therapy for Cartilage and Bone Tissue Engineering written by Yu-Chen Hu and published by Springer Science & Business Media. This book was released on 2014-01-26 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Gene Therapy for Cartilage and Bone Tissue Engineering" outlines the tissue engineering and possible applications of gene therapy in the field of biomedical engineering as well as basic principles of gene therapy, vectors and gene delivery, specifically for cartilage and bone engineering. It is intended for tissue engineers, cell therapists, regenerative medicine scientists and engineers, gene therapist and virologists. Dr. Yu-Chen Hu is a Distinguished Professor at the Department of Chemical Engineering, National Tsing Hua University and has received the Outstanding Research Award (National Science Council), Asia Research Award (Society of Chemical Engineers, Japan) and Professor Tsai-Teh Lai Award (Taiwan Institute of Chemical Engineers). He is also a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and a member of the Tissue Engineering International & Regenerative Medicine Society (TERMIS)-Asia Pacific Council.
Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair
Book Synopsis Developmental Biology and Musculoskeletal Tissue Engineering by : Martin J. Stoddart
Download or read book Developmental Biology and Musculoskeletal Tissue Engineering written by Martin J. Stoddart and published by Academic Press. This book was released on 2018-04-24 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair
Football is probably the most widespread sport in the world: youngsters, adults, women, amateurs, beginners, professionals all make up a legion of practitioners. Lesions associated with football are on the increase and their typology has also changed over the years. Football, like many other sports, has undergone major changes: the increase in the intensity and speed of the game, the modern training methodologies, the technical and tactical innovations are all factors contributing to increased risks of traumatic injury. The footballers, the trainers, the sport's medical staff are asking for greater information and knowledge on the traumatic lesions associated with this sport. The primary role of those who are concerned with the health of footballers is to enforce preventive measures to reduce wherever possible the risks of trauma.
Book Synopsis Football Traumatology by : Piero Volpi
Download or read book Football Traumatology written by Piero Volpi and published by Springer Science & Business Media. This book was released on 2006-01-19 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Football is probably the most widespread sport in the world: youngsters, adults, women, amateurs, beginners, professionals all make up a legion of practitioners. Lesions associated with football are on the increase and their typology has also changed over the years. Football, like many other sports, has undergone major changes: the increase in the intensity and speed of the game, the modern training methodologies, the technical and tactical innovations are all factors contributing to increased risks of traumatic injury. The footballers, the trainers, the sport's medical staff are asking for greater information and knowledge on the traumatic lesions associated with this sport. The primary role of those who are concerned with the health of footballers is to enforce preventive measures to reduce wherever possible the risks of trauma.
With detailed descriptions of orthopedic surgeries, Rehabilitation for the Postsurgical Orthopedic Patient, 3rd Edition provides current, evidence-based guidelines to designing effective rehabilitation strategies. Coverage of each condition includes an overview of the orthopedic patient's entire course of treatment from pre- to post-surgery. For each phase of rehabilitation, this book describes the postoperative timeline, the goals, potential complications and precautions, and appropriate therapeutic procedures. New to this edition are a full-color design and new chapters on disc replacement, cartilage replacement, hallux valgus, and transitioning the running athlete. Edited by Lisa Maxey and Jim Magnusson, and with chapters written by both surgeons and physical therapists, Rehabilitation for the Postsurgical Orthopedic Patient provides valuable insights into the use of physical therapy in the rehabilitation process. Comprehensive, evidence-based coverage provides an overview of the orthopedic patient's entire course of treatment from pre- to post-surgery, including a detailed look at the surgical procedures and therapy guidelines that can be used to design the appropriate rehabilitation programs. Case study vignettes with critical thinking questions help you develop critical reasoning skills. Indications and considerations for surgery describe the mechanics of the injury and the repair process so you can plan an effective rehabilitation program. Therapy guidelines cover each phase of rehabilitation with specifics as to the expected time span and goals for each phase. Evidence-based coverage includes the latest clinical research to support treatment decisions. Overview of soft tissue and bone healing considerations after surgery helps you understand the rationale behind the timelines for the various physical therapy guidelines. A Troubleshooting section in each chapter details potential pitfalls in the recovery from each procedure. Over 300 photos and line drawings depict concepts, procedures, and rehabilitation. Detailed tables break down therapy guidelines and treatment options for quick reference. Expert contributors include surgeons describing the indications and considerations for surgery as well as the surgery itself, and physical or occupational therapists discussing therapy guidelines. New coverage of current orthopedic surgeries and rehabilitation includes topics such as disc replacement, cartilage replacement, hallux valgus, and transitioning the running athlete. New full-color design and illustrations visually reinforce the content. Updated Suggested Home Maintenance boxes in every chapter provide guidance for patients returning home. References linked to MEDLINE abstracts make it easy to access evidence-based information for better clinical decision-making.
Book Synopsis Rehabilitation for the Postsurgical Orthopedic Patient by : Lisa Maxey
Download or read book Rehabilitation for the Postsurgical Orthopedic Patient written by Lisa Maxey and published by Elsevier Health Sciences. This book was released on 2013-01-22 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: With detailed descriptions of orthopedic surgeries, Rehabilitation for the Postsurgical Orthopedic Patient, 3rd Edition provides current, evidence-based guidelines to designing effective rehabilitation strategies. Coverage of each condition includes an overview of the orthopedic patient's entire course of treatment from pre- to post-surgery. For each phase of rehabilitation, this book describes the postoperative timeline, the goals, potential complications and precautions, and appropriate therapeutic procedures. New to this edition are a full-color design and new chapters on disc replacement, cartilage replacement, hallux valgus, and transitioning the running athlete. Edited by Lisa Maxey and Jim Magnusson, and with chapters written by both surgeons and physical therapists, Rehabilitation for the Postsurgical Orthopedic Patient provides valuable insights into the use of physical therapy in the rehabilitation process. Comprehensive, evidence-based coverage provides an overview of the orthopedic patient's entire course of treatment from pre- to post-surgery, including a detailed look at the surgical procedures and therapy guidelines that can be used to design the appropriate rehabilitation programs. Case study vignettes with critical thinking questions help you develop critical reasoning skills. Indications and considerations for surgery describe the mechanics of the injury and the repair process so you can plan an effective rehabilitation program. Therapy guidelines cover each phase of rehabilitation with specifics as to the expected time span and goals for each phase. Evidence-based coverage includes the latest clinical research to support treatment decisions. Overview of soft tissue and bone healing considerations after surgery helps you understand the rationale behind the timelines for the various physical therapy guidelines. A Troubleshooting section in each chapter details potential pitfalls in the recovery from each procedure. Over 300 photos and line drawings depict concepts, procedures, and rehabilitation. Detailed tables break down therapy guidelines and treatment options for quick reference. Expert contributors include surgeons describing the indications and considerations for surgery as well as the surgery itself, and physical or occupational therapists discussing therapy guidelines. New coverage of current orthopedic surgeries and rehabilitation includes topics such as disc replacement, cartilage replacement, hallux valgus, and transitioning the running athlete. New full-color design and illustrations visually reinforce the content. Updated Suggested Home Maintenance boxes in every chapter provide guidance for patients returning home. References linked to MEDLINE abstracts make it easy to access evidence-based information for better clinical decision-making.
This uniquely interdisciplinary book is a practical resource on orthopedic MR imaging that bridges the backgrounds of radiologists and orthopedic surgeons. Radiologists learn why surgeons order imaging studies. They also learn terminology that will help them tailor reports to the specialty. Orthopedic surgeons gain insight on when to order an MRI, how MRI affects decision making, and how to interpret images. Case studies also depict key clinical and exam points, supplemented by MR images and illustrations. Shorter sections highlight other anatomical areas, and additional chapters address diagnostic accuracy and imaging pitfalls.
Book Synopsis Magnetic Resonance Imaging in Orthopedic Sports Medicine by : Robert Pedowitz
Download or read book Magnetic Resonance Imaging in Orthopedic Sports Medicine written by Robert Pedowitz and published by Springer Science & Business Media. This book was released on 2008-12-01 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This uniquely interdisciplinary book is a practical resource on orthopedic MR imaging that bridges the backgrounds of radiologists and orthopedic surgeons. Radiologists learn why surgeons order imaging studies. They also learn terminology that will help them tailor reports to the specialty. Orthopedic surgeons gain insight on when to order an MRI, how MRI affects decision making, and how to interpret images. Case studies also depict key clinical and exam points, supplemented by MR images and illustrations. Shorter sections highlight other anatomical areas, and additional chapters address diagnostic accuracy and imaging pitfalls.
The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.
Book Synopsis Scaffolding In Tissue Engineering by : Peter X. Ma
Download or read book Scaffolding In Tissue Engineering written by Peter X. Ma and published by CRC Press. This book was released on 2005-08-19 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.
This book explores the basic science and clinical concepts impacting bone tissue engineering; considers advances in gene therapy for enhancement of bone and cartilage repair; and presents the biomechanical factors affecting articular cartilage engineering.
Book Synopsis Orthopedic Tissue Engineering by : Victor M. Goldberg
Download or read book Orthopedic Tissue Engineering written by Victor M. Goldberg and published by CRC Press. This book was released on 2004-01-21 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the basic science and clinical concepts impacting bone tissue engineering; considers advances in gene therapy for enhancement of bone and cartilage repair; and presents the biomechanical factors affecting articular cartilage engineering.
