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Handbook of Anticancer Drugs from Marine Origin

Author: Se-Kwon Kim

Publisher: Springer

Published: 2014-11-27

Total Pages: 801

ISBN-13: 3319071459

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This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

Book Synopsis Handbook of Anticancer Drugs from Marine Origin by : Se-Kwon Kim

Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

Handbook of Anticancer Drug Development

Author: Daniel Budman

Publisher: Lippincott Raven

Published: 2003

Total Pages: 502

ISBN-13: 9780781740104

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Perhaps no area of pharmacology has progressed further or faster than that of anticancer drugs. With this concise and informative resource, you'll explore the full spectrum of anticancer drug evolution -- from research and development, through clinical trials, to licensure and utilization.

Book Synopsis Handbook of Anticancer Drug Development by : Daniel Budman

Download or read book Handbook of Anticancer Drug Development written by Daniel Budman and published by Lippincott Raven. This book was released on 2003 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perhaps no area of pharmacology has progressed further or faster than that of anticancer drugs. With this concise and informative resource, you'll explore the full spectrum of anticancer drug evolution -- from research and development, through clinical trials, to licensure and utilization.

Handbook of Anticancer Drug Discovery and Development

Author: Octavia Settle

Publisher: American Medical Publishers

Published: 2023-09-26

Total Pages: 0

ISBN-13: 9781639278800

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Anticancer drugs refer to drugs that are used for treating cancerous or malignant diseases. They are classified into several categories, including antimetabolites, hormones, alkylating agents and natural products. Preclinical research, clinical research and post-clinical research are the three primary steps in the development of a novel drug. Clinical trial evaluation, in vivo confirmation, and in vitro cytotoxicity on cancer cells are the major assessment methods used while creating an anticancer drug. The evaluation of cytotoxicity towards cancer cell lines is a popular method for discovering anticancer agents. New cancer drugs can be discovered in a variety of ways including testing of animals, plants and fungi, understanding the chemical structure of a drug target, unintentional discovery, developing drugs that are similar to existing drugs, and researching the biology of cancer cells. This book unravels the recent studies on anticancer drug discovery and development. Those in search of information to further their knowledge will be greatly assisted by it.

Book Synopsis Handbook of Anticancer Drug Discovery and Development by : Octavia Settle

Download or read book Handbook of Anticancer Drug Discovery and Development written by Octavia Settle and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anticancer drugs refer to drugs that are used for treating cancerous or malignant diseases. They are classified into several categories, including antimetabolites, hormones, alkylating agents and natural products. Preclinical research, clinical research and post-clinical research are the three primary steps in the development of a novel drug. Clinical trial evaluation, in vivo confirmation, and in vitro cytotoxicity on cancer cells are the major assessment methods used while creating an anticancer drug. The evaluation of cytotoxicity towards cancer cell lines is a popular method for discovering anticancer agents. New cancer drugs can be discovered in a variety of ways including testing of animals, plants and fungi, understanding the chemical structure of a drug target, unintentional discovery, developing drugs that are similar to existing drugs, and researching the biology of cancer cells. This book unravels the recent studies on anticancer drug discovery and development. Those in search of information to further their knowledge will be greatly assisted by it.

Marine Antioxidants

Author: Se-Kwon Kim

Publisher: Academic Press

Published: 2022-12-04

Total Pages: 534

ISBN-13: 0323950876

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Marine Antioxidants: Preparations, Syntheses, and Applications provides the most updated and comprehensive knowledge on utilizing marine-derived substances for cosmeceutical, pharmaceutical and nutraceutical developments. The book delivers the isolation procedures and biological activity of marine-derived antioxidant substances as discussed by international experts on antioxidant material from actinobacteria, crustaceans, diatoms, fish, microalgae, microbes, and mangrove-associated marine organisms and seagrasses. In addition, the book details marine-derived bioactive antioxidants substances in the form of proteins, peptides, polysaccharides and lipids. Finally, the book provides the latest information on the mechanistic pathways of antioxidant substances with various diseases and nutritional perspectives. This is an essential resource for marine biotechnologists and marine biologists who want to better understand isolation procedures and antioxidant applications. Researchers interested in pharmaceutical nutrients, polymer science, and cosmeceuticals industries scientists, as well as students and academics, will also benefit from this book. Explores under-utilized marine products for commercial applications Offers isolated information and biological applications of each identified marine antioxidant Discusses the latest approaches to treatments of diseases, such as diabetes, arthritis, and cancer using marine resources

Book Synopsis Marine Antioxidants by : Se-Kwon Kim

Download or read book Marine Antioxidants written by Se-Kwon Kim and published by Academic Press. This book was released on 2022-12-04 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine Antioxidants: Preparations, Syntheses, and Applications provides the most updated and comprehensive knowledge on utilizing marine-derived substances for cosmeceutical, pharmaceutical and nutraceutical developments. The book delivers the isolation procedures and biological activity of marine-derived antioxidant substances as discussed by international experts on antioxidant material from actinobacteria, crustaceans, diatoms, fish, microalgae, microbes, and mangrove-associated marine organisms and seagrasses. In addition, the book details marine-derived bioactive antioxidants substances in the form of proteins, peptides, polysaccharides and lipids. Finally, the book provides the latest information on the mechanistic pathways of antioxidant substances with various diseases and nutritional perspectives. This is an essential resource for marine biotechnologists and marine biologists who want to better understand isolation procedures and antioxidant applications. Researchers interested in pharmaceutical nutrients, polymer science, and cosmeceuticals industries scientists, as well as students and academics, will also benefit from this book. Explores under-utilized marine products for commercial applications Offers isolated information and biological applications of each identified marine antioxidant Discusses the latest approaches to treatments of diseases, such as diabetes, arthritis, and cancer using marine resources

Marine Glycobiology

Author: Se-Kwon Kim

Publisher: CRC Press

Published: 2016-10-14

Total Pages: 520

ISBN-13: 1498709621

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Marine glycobiology is an emerging and exciting area in the field of science and medicine. Glycobiology, the study of the structure and function of carbohydrates and carbohydrate-containing molecules, is fundamental to all biological systems and represents a developing field of science that has made huge advances in the last half-century. This book revolutionizes the concept of marine glycobiology, focusing on the latest principles and applications of marine glycobiology and their relationships.

Book Synopsis Marine Glycobiology by : Se-Kwon Kim

Download or read book Marine Glycobiology written by Se-Kwon Kim and published by CRC Press. This book was released on 2016-10-14 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine glycobiology is an emerging and exciting area in the field of science and medicine. Glycobiology, the study of the structure and function of carbohydrates and carbohydrate-containing molecules, is fundamental to all biological systems and represents a developing field of science that has made huge advances in the last half-century. This book revolutionizes the concept of marine glycobiology, focusing on the latest principles and applications of marine glycobiology and their relationships.

Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics

Author: Pandurangan, Ashok Kumar

Publisher: IGI Global

Published: 2022-03-18

Total Pages: 643

ISBN-13: 1799892603

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Many chemotherapeutic agents are available in today’s market that are highly effective against a variety of cancer types; however, the major drawbacks of these chemotherapeutic agents are the many side effects. As an alternative to these chemotherapeutic agents, there are a number of natural agents that are effective against cancer that have been tested in preclinical and clinical models over the years. These natural products must be documented and discussed in order to provide a thorough overview of all the options available for cancer treatment. The Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics emphasizes the list of natural agents against all types of cancers and discusses the current state of research in the fields of natural products and their derivatives against cancer in preclinical and clinical models. This book also provides insight into the applications of meditation and mindfulness-based interventions in clinical and non-clinical conditions. Covering topics such as cancer therapy, antioxidants, and flavonoids, it is ideal for students, research scholars, academicians, professors, scientists, oncologists, doctors, and medical practitioners.

Book Synopsis Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics by : Pandurangan, Ashok Kumar

Download or read book Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics written by Pandurangan, Ashok Kumar and published by IGI Global. This book was released on 2022-03-18 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many chemotherapeutic agents are available in today’s market that are highly effective against a variety of cancer types; however, the major drawbacks of these chemotherapeutic agents are the many side effects. As an alternative to these chemotherapeutic agents, there are a number of natural agents that are effective against cancer that have been tested in preclinical and clinical models over the years. These natural products must be documented and discussed in order to provide a thorough overview of all the options available for cancer treatment. The Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics emphasizes the list of natural agents against all types of cancers and discusses the current state of research in the fields of natural products and their derivatives against cancer in preclinical and clinical models. This book also provides insight into the applications of meditation and mindfulness-based interventions in clinical and non-clinical conditions. Covering topics such as cancer therapy, antioxidants, and flavonoids, it is ideal for students, research scholars, academicians, professors, scientists, oncologists, doctors, and medical practitioners.

Marine, Waterborne, and Water-Resistant Polymers

Author: Johannes Karl Fink

Publisher: John Wiley & Sons

Published: 2015-10-01

Total Pages: 234

ISBN-13: 1119185025

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This book focuses on the chemistry of marine polymers, waterborne polymers, and water-resistant polymers, as well as the special applications of these materials. After the chemistry of marine polymers and their types are discussed, the uses of these polymers are detailed, as well as various analytical and characterization testing methods. The book also emphasizes the polymers that are most environmentally-friendly along with their origin and industrial applications. The polymers from these 3 types serve a variety of industries including medical equipment and devices, outdoor coatings and corrosion protection, food packaging, saltwater and freshwater marine purposes such as marine ropes, boat coatings, pipeline protection, and marine well application, to name just a few.

Book Synopsis Marine, Waterborne, and Water-Resistant Polymers by : Johannes Karl Fink

Download or read book Marine, Waterborne, and Water-Resistant Polymers written by Johannes Karl Fink and published by John Wiley & Sons. This book was released on 2015-10-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the chemistry of marine polymers, waterborne polymers, and water-resistant polymers, as well as the special applications of these materials. After the chemistry of marine polymers and their types are discussed, the uses of these polymers are detailed, as well as various analytical and characterization testing methods. The book also emphasizes the polymers that are most environmentally-friendly along with their origin and industrial applications. The polymers from these 3 types serve a variety of industries including medical equipment and devices, outdoor coatings and corrosion protection, food packaging, saltwater and freshwater marine purposes such as marine ropes, boat coatings, pipeline protection, and marine well application, to name just a few.

Anticancer Agents from Natural Products, Second Edition

Author: Gordon M. Cragg

Publisher: CRC Press

Published: 2011-10-10

Total Pages: 786

ISBN-13: 1439813825

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The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the: History of each covered drug—a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery Important biosynthetic approaches to "unnatural" natural products Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis—enabled by historic advances in methodology—has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future. Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.

Book Synopsis Anticancer Agents from Natural Products, Second Edition by : Gordon M. Cragg

Download or read book Anticancer Agents from Natural Products, Second Edition written by Gordon M. Cragg and published by CRC Press. This book was released on 2011-10-10 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the: History of each covered drug—a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery Important biosynthetic approaches to "unnatural" natural products Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis—enabled by historic advances in methodology—has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future. Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.

Marine Glycosides

Author: Thomas E Adrian

Publisher: MDPI

Published: 2019-05-03

Total Pages: 264

ISBN-13: 3038979023

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In recent years, there has been a steady increase in the publication of papers on the chemistry, biology, and potential clinical uses of marine glycosides. Indeed, more than half of the papers published in this field are less than a decade old. Glycosides have been isolated from species as diverse as algae, fungi, anthozoans, and echinoderms. Even fish of the genus Pardachirus produce glycosides, which they use as shark repellents.The major interest in these compounds as potential drugs stems from their broad spectrum of biological effects. They have been shown to have antimicrobial, antifungal, anti-inflammatory, immune modulatory, and anticancer effects. The anticancer effects of marine glycosides include cell cycle suppression, the induction of apoptosis, and the inhibition of migration, invasion, and metastasis, as well as antiangiogenesis. Marine glycosides influence membrane permeability and have been shown to influence membrane transport at the molecular level through effects on transport carriers and pumps, as well as effects on ligand-gated and voltage-gated channels. Various marine glycosides have been shown to activate sphingomyelinase and ceramide synthesis, to inhibit topoisomerase activity, receptor tyrosine kinase activity, and multidrug resistance protein activity, and to antagonize eicosanoid receptors.This Special Issue covers the entire scope of marine organism-derived glycosides that are of potential value as pharmaceutical agents or leads. These include, but are not limited to, tetracyclic triterpene glycosides, other triterpene glycosides, steroid glycosides, and glycosides of non-isoprenoid aglycones.

Book Synopsis Marine Glycosides by : Thomas E Adrian

Download or read book Marine Glycosides written by Thomas E Adrian and published by MDPI. This book was released on 2019-05-03 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there has been a steady increase in the publication of papers on the chemistry, biology, and potential clinical uses of marine glycosides. Indeed, more than half of the papers published in this field are less than a decade old. Glycosides have been isolated from species as diverse as algae, fungi, anthozoans, and echinoderms. Even fish of the genus Pardachirus produce glycosides, which they use as shark repellents.The major interest in these compounds as potential drugs stems from their broad spectrum of biological effects. They have been shown to have antimicrobial, antifungal, anti-inflammatory, immune modulatory, and anticancer effects. The anticancer effects of marine glycosides include cell cycle suppression, the induction of apoptosis, and the inhibition of migration, invasion, and metastasis, as well as antiangiogenesis. Marine glycosides influence membrane permeability and have been shown to influence membrane transport at the molecular level through effects on transport carriers and pumps, as well as effects on ligand-gated and voltage-gated channels. Various marine glycosides have been shown to activate sphingomyelinase and ceramide synthesis, to inhibit topoisomerase activity, receptor tyrosine kinase activity, and multidrug resistance protein activity, and to antagonize eicosanoid receptors.This Special Issue covers the entire scope of marine organism-derived glycosides that are of potential value as pharmaceutical agents or leads. These include, but are not limited to, tetracyclic triterpene glycosides, other triterpene glycosides, steroid glycosides, and glycosides of non-isoprenoid aglycones.

A Guide to Intellectual Property Issues in Access and Benefit-sharing Agreements

Author: Maria Julia Oliva

Publisher: WIPO

Published: 2018-06-22

Total Pages: 91

ISBN-13: 9280529129

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An essential complement to the WIPO Database of Access and Benefit-sharing Agreements, this guide offers users and providers of genetic resources an accessible overview of intellectual property issues in access and benefit-sharing agreements.

Book Synopsis A Guide to Intellectual Property Issues in Access and Benefit-sharing Agreements by : Maria Julia Oliva

Download or read book A Guide to Intellectual Property Issues in Access and Benefit-sharing Agreements written by Maria Julia Oliva and published by WIPO. This book was released on 2018-06-22 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential complement to the WIPO Database of Access and Benefit-sharing Agreements, this guide offers users and providers of genetic resources an accessible overview of intellectual property issues in access and benefit-sharing agreements.