Handbook of Therapeutic Antibodies

Handbook of Therapeutic Antibodies

Author: Stefan Dübel

Publisher: John Wiley & Sons

Published: 2014-12-03

Total Pages: 2538

ISBN-13: 3527329374

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Still the most comprehensive reference source on the development, production and therapeutic application of antibodies, this second edition is thoroughly updated and now has 30% more content. Volume 1 covers selection and engineering strategies for new antibodies, while the second volume presents novel therapeutic concepts and antibodies in clinical study, as well as their potential. Volumes 3 and 4 feature detailed and specific information about each antibody approved for therapeutic purposes, including clinical data. This unique handbook concludes with a compendium of marketed monoclonal antibodies and an extensive index. Beyond providing current knowledge, the authors discuss emerging technologies, future developments, and intellectual property issues, such that this handbook meets the needs of academic researchers, decision makers in industry and healthcare professionals in the clinic.


Book Synopsis Handbook of Therapeutic Antibodies by : Stefan Dübel

Download or read book Handbook of Therapeutic Antibodies written by Stefan Dübel and published by John Wiley & Sons. This book was released on 2014-12-03 with total page 2538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Still the most comprehensive reference source on the development, production and therapeutic application of antibodies, this second edition is thoroughly updated and now has 30% more content. Volume 1 covers selection and engineering strategies for new antibodies, while the second volume presents novel therapeutic concepts and antibodies in clinical study, as well as their potential. Volumes 3 and 4 feature detailed and specific information about each antibody approved for therapeutic purposes, including clinical data. This unique handbook concludes with a compendium of marketed monoclonal antibodies and an extensive index. Beyond providing current knowledge, the authors discuss emerging technologies, future developments, and intellectual property issues, such that this handbook meets the needs of academic researchers, decision makers in industry and healthcare professionals in the clinic.


Handbook of Therapeutic Antibodies, 3 Volume Set

Handbook of Therapeutic Antibodies, 3 Volume Set

Author: Stefan Dübel

Publisher: Wiley-Blackwell

Published: 2007-03-26

Total Pages: 0

ISBN-13: 9783527314539

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In this most comprehensive reference source for the development, production and therapeutic application of antibodies, Volume I contains general chapters presenting established technologies and clinical applications. Volume II provides a look at emerging technologies, new therapeutic concepts, and clinical studies. The third volume features detailed and specific information about each currently approved type of antibody, including the clinical data. A must-have resource for academic researchers, decision makers in industry and healthcare professionals in the clinic.


Book Synopsis Handbook of Therapeutic Antibodies, 3 Volume Set by : Stefan Dübel

Download or read book Handbook of Therapeutic Antibodies, 3 Volume Set written by Stefan Dübel and published by Wiley-Blackwell. This book was released on 2007-03-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this most comprehensive reference source for the development, production and therapeutic application of antibodies, Volume I contains general chapters presenting established technologies and clinical applications. Volume II provides a look at emerging technologies, new therapeutic concepts, and clinical studies. The third volume features detailed and specific information about each currently approved type of antibody, including the clinical data. A must-have resource for academic researchers, decision makers in industry and healthcare professionals in the clinic.


Handbook of Therapeutic Antibodies

Handbook of Therapeutic Antibodies

Author: Stefan Dübel

Publisher:

Published: 2007

Total Pages: 416

ISBN-13:

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Comprehensive reference source for the development, production and therapeutic application of antibodies. Volume I contains general chapters presenting established technologies and clinical applications. Volume II provides a look at emerging technologies, new therapeutic concepts, and clinical studies. Volume III features detailed and specific information about each currently approved type of antibody, including the clinical data.


Book Synopsis Handbook of Therapeutic Antibodies by : Stefan Dübel

Download or read book Handbook of Therapeutic Antibodies written by Stefan Dübel and published by . This book was released on 2007 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive reference source for the development, production and therapeutic application of antibodies. Volume I contains general chapters presenting established technologies and clinical applications. Volume II provides a look at emerging technologies, new therapeutic concepts, and clinical studies. Volume III features detailed and specific information about each currently approved type of antibody, including the clinical data.


Handbook of Therapeutic Antibodies

Handbook of Therapeutic Antibodies

Author: Stefan Dübel

Publisher: Wiley-Blackwell

Published: 2010-08-30

Total Pages: 0

ISBN-13: 9783527329021

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This most comprehensive reference source for the development, production and therapeutic application of antibodies is now available as a competitively priced softcover edition. It includes general chapters presenting established technologies and clinical applications, chapters on emerging technologies, new therapeutic concepts, and clinical studies and detailed and specific information about currently approved therapeutic antibodies, including clinical data. Nearly 100 international experts and researchers from academia, industry, and such regulating bodies as the FDA have contributed to this work. Includes are also information on intellectual property issues, hardly available elsewhere. A must-have resource for academic researchers, decision makers in industry and healthcare professionals in the clinic. From the foreword by Mark Glassy, Chairman & Professor, The Rajko Medenica Research Foundation, and Chief Executive Officer, Shantha West, Inc., San Diego, CA, USA: "After more than a century of intense analysis, antibodies continue to amaze and inspire. This Handbook of Therapeutic Antibodies is not just an assembly of articles but rather a state-of-the-art comprehensive compendium, which will appeal to all those interested in antibodies, whether from academia, industry, or the clinic. It is an unrivalled resource which shows how mature the antibody field has become and how precisely the antibody molecule can be manipulated and utilized." Stefan Dubel studied biology at the universities of Mainz and Heidelberg, initially concentrating on developmental biology. From 1989 onwards he carried out pioneering work on antibody phage display and antibody libraries with randomised CDRs. Further work focussed on antibody fusion proteins and improvements of antibody phage display. Currently he is Director of the Department of Biotechnology at the Technical University of Braunschweig and coordinator of the 'Antibody Factory' within the German National Genome Research Network. Stefan Dubel has co-authored a number of textbooks, about 90 publications and 15 patents in the field of recombinant antibodies and phage display.


Book Synopsis Handbook of Therapeutic Antibodies by : Stefan Dübel

Download or read book Handbook of Therapeutic Antibodies written by Stefan Dübel and published by Wiley-Blackwell. This book was released on 2010-08-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This most comprehensive reference source for the development, production and therapeutic application of antibodies is now available as a competitively priced softcover edition. It includes general chapters presenting established technologies and clinical applications, chapters on emerging technologies, new therapeutic concepts, and clinical studies and detailed and specific information about currently approved therapeutic antibodies, including clinical data. Nearly 100 international experts and researchers from academia, industry, and such regulating bodies as the FDA have contributed to this work. Includes are also information on intellectual property issues, hardly available elsewhere. A must-have resource for academic researchers, decision makers in industry and healthcare professionals in the clinic. From the foreword by Mark Glassy, Chairman & Professor, The Rajko Medenica Research Foundation, and Chief Executive Officer, Shantha West, Inc., San Diego, CA, USA: "After more than a century of intense analysis, antibodies continue to amaze and inspire. This Handbook of Therapeutic Antibodies is not just an assembly of articles but rather a state-of-the-art comprehensive compendium, which will appeal to all those interested in antibodies, whether from academia, industry, or the clinic. It is an unrivalled resource which shows how mature the antibody field has become and how precisely the antibody molecule can be manipulated and utilized." Stefan Dubel studied biology at the universities of Mainz and Heidelberg, initially concentrating on developmental biology. From 1989 onwards he carried out pioneering work on antibody phage display and antibody libraries with randomised CDRs. Further work focussed on antibody fusion proteins and improvements of antibody phage display. Currently he is Director of the Department of Biotechnology at the Technical University of Braunschweig and coordinator of the 'Antibody Factory' within the German National Genome Research Network. Stefan Dubel has co-authored a number of textbooks, about 90 publications and 15 patents in the field of recombinant antibodies and phage display.


Therapeutic Antibodies

Therapeutic Antibodies

Author: Yuti Chernajovsky

Publisher: Springer Science & Business Media

Published: 2007-12-11

Total Pages: 381

ISBN-13: 3540732594

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This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.


Book Synopsis Therapeutic Antibodies by : Yuti Chernajovsky

Download or read book Therapeutic Antibodies written by Yuti Chernajovsky and published by Springer Science & Business Media. This book was released on 2007-12-11 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.


Making and Using Antibodies

Making and Using Antibodies

Author: Gary C. Howard

Publisher: CRC Press

Published: 2006-12-13

Total Pages: 412

ISBN-13: 1420005197

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Antibodies are an indispensable tool in the study of biology and medicine. Making and Using Antibodies: A Practical Handbook presents techniques in a single, comprehensive source for the production and use of antibodies. It enables researchers to immediately access lab-tested, proven protocols. Written and edited by an elite team of scienti


Book Synopsis Making and Using Antibodies by : Gary C. Howard

Download or read book Making and Using Antibodies written by Gary C. Howard and published by CRC Press. This book was released on 2006-12-13 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibodies are an indispensable tool in the study of biology and medicine. Making and Using Antibodies: A Practical Handbook presents techniques in a single, comprehensive source for the production and use of antibodies. It enables researchers to immediately access lab-tested, proven protocols. Written and edited by an elite team of scienti


Biosimilars of Monoclonal Antibodies

Biosimilars of Monoclonal Antibodies

Author: Cheng Liu

Publisher: John Wiley & Sons

Published: 2016-12-19

Total Pages: 720

ISBN-13: 1118662318

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Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing. • Guides readers through the complex landscape involved with developing biosimilar versions of monoclonal antibody (mAb) drugs • Features flow charts, tables, and figures that clearly illustrate processes and makes the book comprehensible and accessible • Includes a review of FDA-approved mAb drugs as a quick reference to facts and useful information • Examines new technologies and strategies for improving biosimilar mAbs


Book Synopsis Biosimilars of Monoclonal Antibodies by : Cheng Liu

Download or read book Biosimilars of Monoclonal Antibodies written by Cheng Liu and published by John Wiley & Sons. This book was released on 2016-12-19 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing. • Guides readers through the complex landscape involved with developing biosimilar versions of monoclonal antibody (mAb) drugs • Features flow charts, tables, and figures that clearly illustrate processes and makes the book comprehensible and accessible • Includes a review of FDA-approved mAb drugs as a quick reference to facts and useful information • Examines new technologies and strategies for improving biosimilar mAbs


The Pharmacology of Monoclonal Antibodies

The Pharmacology of Monoclonal Antibodies

Author: Martin Rosenberg

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 414

ISBN-13: 3642784321

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A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents. Leading scientists from academia and industry present their own findings as well as short reviews of these research areas.


Book Synopsis The Pharmacology of Monoclonal Antibodies by : Martin Rosenberg

Download or read book The Pharmacology of Monoclonal Antibodies written by Martin Rosenberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents. Leading scientists from academia and industry present their own findings as well as short reviews of these research areas.


Therapeutic Antibodies

Therapeutic Antibodies

Author: Gunnar Houen

Publisher: Humana

Published: 2021-07-28

Total Pages: 347

ISBN-13: 9781071614495

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This detailed book covers methods for studying, producing, and analyzing therapeutic antibodies, measuring their concentration, developing neutralizing antibodies for them, and for predicting and monitoring their therapeutic efficacy and clinical effects. These biologics are the fastest growing pharmaceutical drug group and have had tremendous clinical and scientific impact in cancer, autoimmune diseases, infectious diseases, and other immune-related diseases, making the content of this volume essential. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible methods, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Therapeutic Antibodies: Methods and Protocols serves as an ideal guide for researchers working with the production of, research on, and development of therapeutic antibodies as well as for clinicians using therapeutic antibodies in daily work with patients.


Book Synopsis Therapeutic Antibodies by : Gunnar Houen

Download or read book Therapeutic Antibodies written by Gunnar Houen and published by Humana. This book was released on 2021-07-28 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book covers methods for studying, producing, and analyzing therapeutic antibodies, measuring their concentration, developing neutralizing antibodies for them, and for predicting and monitoring their therapeutic efficacy and clinical effects. These biologics are the fastest growing pharmaceutical drug group and have had tremendous clinical and scientific impact in cancer, autoimmune diseases, infectious diseases, and other immune-related diseases, making the content of this volume essential. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible methods, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Therapeutic Antibodies: Methods and Protocols serves as an ideal guide for researchers working with the production of, research on, and development of therapeutic antibodies as well as for clinicians using therapeutic antibodies in daily work with patients.


Making and Using Antibodies

Making and Using Antibodies

Author: Gary C. Howard

Publisher: CRC Press

Published: 2013-07-29

Total Pages: 462

ISBN-13: 1439869081

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Antibodies protect us from a wide range of infectious diseases and cancers and have become an indispensable tool in science—both for conventional immune response research as well as other areas related to protein identification analysis. This second edition of Making and Using Antibodies: A Practical Handbook provides clear guidance on all aspects of how to make and use antibodies for research along with their commercial and industrial applications. Keeping pace with new developments in this area, all chapters in this new edition have been revised, updated, or expanded. Along with discussions of current applications, new material in the book includes chapters on western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present clear descriptions of basic methods for making and using antibodies and supply detailed descriptions of basic laboratory techniques. Each chapter begins with introductory material, allowing for a better understanding of each concept, and practical examples are included to help readers grasp the real-world scenarios in which antibodies play a part. From the eradication of smallpox to combating cancer, antibodies present an attractive solution to a range of biomedical problems. They are relatively easy to make and use, have great flexibility in applications, and are cost effective for most labs. This volume will assist biomedical researchers and students and pave the way for future discovery of new methods for making and using antibodies for a host of applications.


Book Synopsis Making and Using Antibodies by : Gary C. Howard

Download or read book Making and Using Antibodies written by Gary C. Howard and published by CRC Press. This book was released on 2013-07-29 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibodies protect us from a wide range of infectious diseases and cancers and have become an indispensable tool in science—both for conventional immune response research as well as other areas related to protein identification analysis. This second edition of Making and Using Antibodies: A Practical Handbook provides clear guidance on all aspects of how to make and use antibodies for research along with their commercial and industrial applications. Keeping pace with new developments in this area, all chapters in this new edition have been revised, updated, or expanded. Along with discussions of current applications, new material in the book includes chapters on western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present clear descriptions of basic methods for making and using antibodies and supply detailed descriptions of basic laboratory techniques. Each chapter begins with introductory material, allowing for a better understanding of each concept, and practical examples are included to help readers grasp the real-world scenarios in which antibodies play a part. From the eradication of smallpox to combating cancer, antibodies present an attractive solution to a range of biomedical problems. They are relatively easy to make and use, have great flexibility in applications, and are cost effective for most labs. This volume will assist biomedical researchers and students and pave the way for future discovery of new methods for making and using antibodies for a host of applications.