Hibernation and the Hypothalamus

Hibernation and the Hypothalamus

Author: Nicholas Mrosovsky

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 296

ISBN-13: 1468471767

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Mammalian hibernation is commonly thought of as something completely out of the ordinary, a "unique and unorthodox state." The present book takes the opposite view. It argues that the physiological achievements of hibernators do not deEend on special mechanisms but on special use of ordinary mechanisms. It is precisely this that makes the hibernators important. If the hibernators de pend on some unique physiological principle their study is that of a biological curio. But if they are using basic mammalian systems in a quantitatively extreme way, then they are a naturally occurring preparation of enormous potential. Hibernation involves every aspect of the animal's biology from fat metabo lism to behavior, from thermoregulation to dental caries; every system in the body is affected in some way or other by hibernation. A comprehensive account of hibernation would be almost coextensive with an account of the whole of mammalian biology. The present book does not attempt to describe everything that has been discovered about hibernation. Excellent coverage for that already exists in the proceedings of three recent symposia and in the other major source materials listed on page 233. There is in fact an enormous amount of information already available. But there is a difference between information and understanding. Despite the increasing volume of research and growing interest in mammalian hibernation, there is little appreciation of the essential characteristics of the phenomena. The pieces of the puzzle lie scattered.


Book Synopsis Hibernation and the Hypothalamus by : Nicholas Mrosovsky

Download or read book Hibernation and the Hypothalamus written by Nicholas Mrosovsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian hibernation is commonly thought of as something completely out of the ordinary, a "unique and unorthodox state." The present book takes the opposite view. It argues that the physiological achievements of hibernators do not deEend on special mechanisms but on special use of ordinary mechanisms. It is precisely this that makes the hibernators important. If the hibernators de pend on some unique physiological principle their study is that of a biological curio. But if they are using basic mammalian systems in a quantitatively extreme way, then they are a naturally occurring preparation of enormous potential. Hibernation involves every aspect of the animal's biology from fat metabo lism to behavior, from thermoregulation to dental caries; every system in the body is affected in some way or other by hibernation. A comprehensive account of hibernation would be almost coextensive with an account of the whole of mammalian biology. The present book does not attempt to describe everything that has been discovered about hibernation. Excellent coverage for that already exists in the proceedings of three recent symposia and in the other major source materials listed on page 233. There is in fact an enormous amount of information already available. But there is a difference between information and understanding. Despite the increasing volume of research and growing interest in mammalian hibernation, there is little appreciation of the essential characteristics of the phenomena. The pieces of the puzzle lie scattered.


The Brain of Hibernating Animals

The Brain of Hibernating Animals

Author: Mark Borisovich Shtark

Publisher:

Published: 1972

Total Pages: 236

ISBN-13:

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Book Synopsis The Brain of Hibernating Animals by : Mark Borisovich Shtark

Download or read book The Brain of Hibernating Animals written by Mark Borisovich Shtark and published by . This book was released on 1972 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Hibernation and Torpor in Mammals and Birds

Hibernation and Torpor in Mammals and Birds

Author: Charles P Lyman

Publisher: Elsevier

Published: 2013-07-10

Total Pages: 332

ISBN-13: 0323138241

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Hibernation and Torpor in Mammals and Birds explores the physiological factors that control hibernation and torpor in birds and mammals. This text covers topics ranging from metabolism in hibernation to the role of endocrines, respiration and acid-base state in hibernation, and theories of hibernation. This book is comprised of 14 chapters and begins with an overview of some clear-cut definitions and why mammals and birds hibernate. The reader is then introduced to the variations from euthermia that have been observed among birds and mammals. To give some structure to this listing, the approach is phylogenetic, starting with the birds and proceeding through the primitive to the more advanced mammals. Subsequent chapters explains the process of entering hibernation and the hibernating state, itself; capability of a species in natural hibernation to arouse from that state using self-generated heat; physiological changes at the start of a spontaneous arousal; and physiological mechanisms underlying the ability of hibernators to rewarm. Consideration is also given to intermediary metabolism in hibernation, cold adaptation of metabolism in hibernators, and the response of hibernators to various extrinsic influences such as neoplastic growth, radiation injury, and parasitism and symbionts. This book will be of interest to students and researchers in fields ranging from zoology to physiology and biophysics.


Book Synopsis Hibernation and Torpor in Mammals and Birds by : Charles P Lyman

Download or read book Hibernation and Torpor in Mammals and Birds written by Charles P Lyman and published by Elsevier. This book was released on 2013-07-10 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hibernation and Torpor in Mammals and Birds explores the physiological factors that control hibernation and torpor in birds and mammals. This text covers topics ranging from metabolism in hibernation to the role of endocrines, respiration and acid-base state in hibernation, and theories of hibernation. This book is comprised of 14 chapters and begins with an overview of some clear-cut definitions and why mammals and birds hibernate. The reader is then introduced to the variations from euthermia that have been observed among birds and mammals. To give some structure to this listing, the approach is phylogenetic, starting with the birds and proceeding through the primitive to the more advanced mammals. Subsequent chapters explains the process of entering hibernation and the hibernating state, itself; capability of a species in natural hibernation to arouse from that state using self-generated heat; physiological changes at the start of a spontaneous arousal; and physiological mechanisms underlying the ability of hibernators to rewarm. Consideration is also given to intermediary metabolism in hibernation, cold adaptation of metabolism in hibernators, and the response of hibernators to various extrinsic influences such as neoplastic growth, radiation injury, and parasitism and symbionts. This book will be of interest to students and researchers in fields ranging from zoology to physiology and biophysics.


The Orexin System. Basic Science and Role in Sleep Pathology

The Orexin System. Basic Science and Role in Sleep Pathology

Author: M.A. Steiner

Publisher: Karger Medical and Scientific Publishers

Published: 2021-05-28

Total Pages: 165

ISBN-13: 3318068446

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The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.


Book Synopsis The Orexin System. Basic Science and Role in Sleep Pathology by : M.A. Steiner

Download or read book The Orexin System. Basic Science and Role in Sleep Pathology written by M.A. Steiner and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.


Hibernation and Hypothermia, Perspectives and Challenges

Hibernation and Hypothermia, Perspectives and Challenges

Author: University of Missouri. Space Sciences Research Center

Publisher:

Published: 1972

Total Pages: 778

ISBN-13:

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Book Synopsis Hibernation and Hypothermia, Perspectives and Challenges by : University of Missouri. Space Sciences Research Center

Download or read book Hibernation and Hypothermia, Perspectives and Challenges written by University of Missouri. Space Sciences Research Center and published by . This book was released on 1972 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Hunger, Thirst, Sex, and Sleep

Hunger, Thirst, Sex, and Sleep

Author: John K. Young

Publisher: Rowman & Littlefield Publishers

Published: 2012-08-09

Total Pages: 178

ISBN-13: 1442218258

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Sensations of hunger, thirst, sexual attraction, and love can dominate our thoughts to the exclusion of almost everything else, but until the last 10 years or so, the precise reasons why these passions arise have not been understood very well. We now know that these, and other drives like the urge to sleep, are controlled by a small portion of the brain called the hypothalamus. This book presents the latest information about how the brain controls our most basic drives. In a series of fascinating anecdotes, Young tells the tale of how scientists have discovered the role of the hypothalamus in our basic drives and in medical conditions in which these drives are drastically altered. Covering our need for food, water, sex, sleep, and other life essentials, he reveals the brain’s part in how we provide for each, and how in some cases, those needs can swing wildly out of control resulting in problems such as obesity, diabetes, insomnia, or narcolepsy. He shows how regulating body temperature can affect the lifespan, how the aging process affects sexual behavior, how empathy and love develop in relationships with family members or with love interests, and how all these functions and more can go awry. Like other science writers before him, Young illuminates even the complex inner workings of the brain in a way that anyone can understand, so that readers are treated to a tour of a tiny part of the brain that is responsible for so many fundamental aspects of life.


Book Synopsis Hunger, Thirst, Sex, and Sleep by : John K. Young

Download or read book Hunger, Thirst, Sex, and Sleep written by John K. Young and published by Rowman & Littlefield Publishers. This book was released on 2012-08-09 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensations of hunger, thirst, sexual attraction, and love can dominate our thoughts to the exclusion of almost everything else, but until the last 10 years or so, the precise reasons why these passions arise have not been understood very well. We now know that these, and other drives like the urge to sleep, are controlled by a small portion of the brain called the hypothalamus. This book presents the latest information about how the brain controls our most basic drives. In a series of fascinating anecdotes, Young tells the tale of how scientists have discovered the role of the hypothalamus in our basic drives and in medical conditions in which these drives are drastically altered. Covering our need for food, water, sex, sleep, and other life essentials, he reveals the brain’s part in how we provide for each, and how in some cases, those needs can swing wildly out of control resulting in problems such as obesity, diabetes, insomnia, or narcolepsy. He shows how regulating body temperature can affect the lifespan, how the aging process affects sexual behavior, how empathy and love develop in relationships with family members or with love interests, and how all these functions and more can go awry. Like other science writers before him, Young illuminates even the complex inner workings of the brain in a way that anyone can understand, so that readers are treated to a tour of a tiny part of the brain that is responsible for so many fundamental aspects of life.


Torpor and Hibernation: Metabolic and Physiological Paradigms

Torpor and Hibernation: Metabolic and Physiological Paradigms

Author: Sylvain Giroud

Publisher: Frontiers Media SA

Published: 2024-06-21

Total Pages: 138

ISBN-13: 2832550622

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Torpor or heterothermy corresponds to a state of depressed metabolism and is associated with specific metabolic, cellular and molecular adaptations that often occur on a seasonal basis. Yet the exact mechanisms and functioning of these changes are poorly understood. Interestingly, the potential of such extraordinary animal adaptation for human and animal health as well as other biomedical considerations has raised particular attention especially in the last decade. The strong metabolic and physiological adaptations of heterotherms can be of particular inspiration for current biomedical and pathological situations (e.g., obesity and related diseases, cardiovascular and metabolic dysfunctions, ischemia-reperfusion injuries, immune depression) and for the health and longevity of animal species, including humans.


Book Synopsis Torpor and Hibernation: Metabolic and Physiological Paradigms by : Sylvain Giroud

Download or read book Torpor and Hibernation: Metabolic and Physiological Paradigms written by Sylvain Giroud and published by Frontiers Media SA. This book was released on 2024-06-21 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Torpor or heterothermy corresponds to a state of depressed metabolism and is associated with specific metabolic, cellular and molecular adaptations that often occur on a seasonal basis. Yet the exact mechanisms and functioning of these changes are poorly understood. Interestingly, the potential of such extraordinary animal adaptation for human and animal health as well as other biomedical considerations has raised particular attention especially in the last decade. The strong metabolic and physiological adaptations of heterotherms can be of particular inspiration for current biomedical and pathological situations (e.g., obesity and related diseases, cardiovascular and metabolic dysfunctions, ischemia-reperfusion injuries, immune depression) and for the health and longevity of animal species, including humans.


Brain Hypothermia

Brain Hypothermia

Author: N. Hayashi

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 253

ISBN-13: 4431668829

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Rapid progress in technology and its application to diagnosis and monitoring of brain tissue temperature and metabolism have resulted in advances in the therapy for critically brain-injured patients and breakthroughs in understanding the pathophysiology of brain damage. The latest concept of brain hypothermia therapy clarifies targets such as brain thermal pooling, masking brain hypoxia associated with catecholamine surge, the metabolic shift from glucose to lipids, and selective radical damage of dopamine in the central nervous system. This volume explains the mechanism of brain injury and how brain hypothermia treatment differs from other hypothermia therapy in four major sections: Brain Injury Mechanism, Pathophysiology of Hypothermia, Basic Research of Hypothermia Treatment, and Clinical Studies of Brain Hypothermia. The book is a valuable source for practitioners and researchers in neurosurgery and neurology and in critical care and emergency medicine.


Book Synopsis Brain Hypothermia by : N. Hayashi

Download or read book Brain Hypothermia written by N. Hayashi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress in technology and its application to diagnosis and monitoring of brain tissue temperature and metabolism have resulted in advances in the therapy for critically brain-injured patients and breakthroughs in understanding the pathophysiology of brain damage. The latest concept of brain hypothermia therapy clarifies targets such as brain thermal pooling, masking brain hypoxia associated with catecholamine surge, the metabolic shift from glucose to lipids, and selective radical damage of dopamine in the central nervous system. This volume explains the mechanism of brain injury and how brain hypothermia treatment differs from other hypothermia therapy in four major sections: Brain Injury Mechanism, Pathophysiology of Hypothermia, Basic Research of Hypothermia Treatment, and Clinical Studies of Brain Hypothermia. The book is a valuable source for practitioners and researchers in neurosurgery and neurology and in critical care and emergency medicine.


Pituitary Adenylate Cyclase-Activating Polypeptide

Pituitary Adenylate Cyclase-Activating Polypeptide

Author: Hubert Vaudry

Publisher: Springer Science & Business Media

Published: 2003

Total Pages: 432

ISBN-13: 9781402073069

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Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.


Book Synopsis Pituitary Adenylate Cyclase-Activating Polypeptide by : Hubert Vaudry

Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.


Micro-, Meso- and Macro-Dynamics of the Brain

Micro-, Meso- and Macro-Dynamics of the Brain

Author: György Buzsáki

Publisher: Springer

Published: 2016-05-02

Total Pages: 181

ISBN-13: 3319288024

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This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.


Book Synopsis Micro-, Meso- and Macro-Dynamics of the Brain by : György Buzsáki

Download or read book Micro-, Meso- and Macro-Dynamics of the Brain written by György Buzsáki and published by Springer. This book was released on 2016-05-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.