High-Performance In-Memory Genome Data Analysis

High-Performance In-Memory Genome Data Analysis

Author: Hasso Plattner

Publisher: Springer Science & Business Media

Published: 2013-11-19

Total Pages: 239

ISBN-13: 3319030353

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Recent achievements in hardware and software developments have enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of data, such as diagnoses, therapies, and human genome data. This book shares the latest research results of applying in-memory data management to personalized medicine, changing it from computational possibility to clinical reality. The authors provide details on innovative approaches to enabling the processing, combination, and analysis of relevant data in real-time. The book bridges the gap between medical experts, such as physicians, clinicians, and biological researchers, and technology experts, such as software developers, database specialists, and statisticians. Topics covered in this book include - amongst others - modeling of genome data processing and analysis pipelines, high-throughput data processing, exchange of sensitive data and protection of intellectual property. Beyond that, it shares insights on research prototypes for the analysis of patient cohorts, topology analysis of biological pathways, and combined search in structured and unstructured medical data, and outlines completely new processes that have now become possible due to interactive data analyses.


Book Synopsis High-Performance In-Memory Genome Data Analysis by : Hasso Plattner

Download or read book High-Performance In-Memory Genome Data Analysis written by Hasso Plattner and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent achievements in hardware and software developments have enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of data, such as diagnoses, therapies, and human genome data. This book shares the latest research results of applying in-memory data management to personalized medicine, changing it from computational possibility to clinical reality. The authors provide details on innovative approaches to enabling the processing, combination, and analysis of relevant data in real-time. The book bridges the gap between medical experts, such as physicians, clinicians, and biological researchers, and technology experts, such as software developers, database specialists, and statisticians. Topics covered in this book include - amongst others - modeling of genome data processing and analysis pipelines, high-throughput data processing, exchange of sensitive data and protection of intellectual property. Beyond that, it shares insights on research prototypes for the analysis of patient cohorts, topology analysis of biological pathways, and combined search in structured and unstructured medical data, and outlines completely new processes that have now become possible due to interactive data analyses.

A Course in In-Memory Data Management

A Course in In-Memory Data Management

Author: Hasso Plattner

Publisher: Springer

Published: 2014-05-28

Total Pages: 315

ISBN-13: 3642552706

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Recent achievements in hardware and software development, such as multi-core CPUs and DRAM capacities of multiple terabytes per server, enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of enterprise data. Professor Hasso Plattner and his research group at the Hasso Plattner Institute in Potsdam, Germany, have been investigating and teaching the corresponding concepts and their adoption in the software industry for years. This book is based on an online course that was first launched in autumn 2012 with more than 13,000 enrolled students and marked the successful starting point of the openHPI e-learning platform. The course is mainly designed for students of computer science, software engineering, and IT related subjects, but addresses business experts, software developers, technology experts, and IT analysts alike. Plattner and his group focus on exploring the inner mechanics of a column-oriented dictionary-encoded in-memory database. Covered topics include - amongst others - physical data storage and access, basic database operators, compression mechanisms, and parallel join algorithms. Beyond that, implications for future enterprise applications and their development are discussed. Step by step, readers will understand the radical differences and advantages of the new technology over traditional row-oriented, disk-based databases. In this completely revised 2nd edition, we incorporate the feedback of thousands of course participants on openHPI and take into account latest advancements in hard- and software. Improved figures, explanations, and examples further ease the understanding of the concepts presented. We introduce advanced data management techniques such as transparent aggregate caches and provide new showcases that demonstrate the potential of in-memory databases for two diverse industries: retail and life sciences.


Book Synopsis A Course in In-Memory Data Management by : Hasso Plattner

Download or read book A Course in In-Memory Data Management written by Hasso Plattner and published by Springer. This book was released on 2014-05-28 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent achievements in hardware and software development, such as multi-core CPUs and DRAM capacities of multiple terabytes per server, enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of enterprise data. Professor Hasso Plattner and his research group at the Hasso Plattner Institute in Potsdam, Germany, have been investigating and teaching the corresponding concepts and their adoption in the software industry for years. This book is based on an online course that was first launched in autumn 2012 with more than 13,000 enrolled students and marked the successful starting point of the openHPI e-learning platform. The course is mainly designed for students of computer science, software engineering, and IT related subjects, but addresses business experts, software developers, technology experts, and IT analysts alike. Plattner and his group focus on exploring the inner mechanics of a column-oriented dictionary-encoded in-memory database. Covered topics include - amongst others - physical data storage and access, basic database operators, compression mechanisms, and parallel join algorithms. Beyond that, implications for future enterprise applications and their development are discussed. Step by step, readers will understand the radical differences and advantages of the new technology over traditional row-oriented, disk-based databases. In this completely revised 2nd edition, we incorporate the feedback of thousands of course participants on openHPI and take into account latest advancements in hard- and software. Improved figures, explanations, and examples further ease the understanding of the concepts presented. We introduce advanced data management techniques such as transparent aggregate caches and provide new showcases that demonstrate the potential of in-memory databases for two diverse industries: retail and life sciences.

Advanced Information Networking and Applications

Advanced Information Networking and Applications

Author: Leonard Barolli

Publisher: Springer Nature

Published: 2021-04-30

Total Pages: 753

ISBN-13: 3030750787

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This book covers the theory, design and applications of computer networks, distributed computing and information systems. Networks of today are going through a rapid evolution, and there are many emerging areas of information networking and their applications. Heterogeneous networking supported by recent technological advances in low-power wireless communications along with silicon integration of various functionalities such as sensing, communications, intelligence and actuations is emerging as a critically important disruptive computer class based on a new platform, networking structure and interface that enable novel, low-cost and high-volume applications. Several of such applications have been difficult to realize because of many interconnections problems. To fulfill their large range of applications, different kinds of networks need to collaborate, and wired and next-generation wireless systems should be integrated in order to develop high-performance computing solutions to problems arising from the complexities of these networks. The aim of the book “Advanced Information Networking and Applications” is to provide latest research findings, innovative research results, methods and development techniques from both theoretical and practical perspectives related to the emerging areas of information networking and applications.


Book Synopsis Advanced Information Networking and Applications by : Leonard Barolli

Download or read book Advanced Information Networking and Applications written by Leonard Barolli and published by Springer Nature. This book was released on 2021-04-30 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the theory, design and applications of computer networks, distributed computing and information systems. Networks of today are going through a rapid evolution, and there are many emerging areas of information networking and their applications. Heterogeneous networking supported by recent technological advances in low-power wireless communications along with silicon integration of various functionalities such as sensing, communications, intelligence and actuations is emerging as a critically important disruptive computer class based on a new platform, networking structure and interface that enable novel, low-cost and high-volume applications. Several of such applications have been difficult to realize because of many interconnections problems. To fulfill their large range of applications, different kinds of networks need to collaborate, and wired and next-generation wireless systems should be integrated in order to develop high-performance computing solutions to problems arising from the complexities of these networks. The aim of the book “Advanced Information Networking and Applications” is to provide latest research findings, innovative research results, methods and development techniques from both theoretical and practical perspectives related to the emerging areas of information networking and applications.

Real-Time Business Intelligence and Analytics

Real-Time Business Intelligence and Analytics

Author: Malu Castellanos

Publisher: Springer Nature

Published: 2019-10-10

Total Pages: 230

ISBN-13: 3030241246

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This book constitutes the thoroughly refereed conference proceedings of the BIRTE workshops listed below, which were held in in conjunction with VLDB, the International Conference on Very Large Data Bases: 9th International Workshop on Business Intelligence for the Real-Time Enterprise, BIRTE 2015, held in Kohala Coast, Hawaii, in August 2015, 10th International Workshop on Enabling Real-Time Business Intelligence, BIRTE 2016, held in New Delhi, India, in September 2016, 11th International Workshop on Real-Time Business Intelligence and Analytics, BIRTE 2017, held in Munich, Germany, in August 2017. The BIRTE workshop series provides a forum for the discussion and advancement of the science and engineering enabling real-time business intelligence and the novel applications that build on these foundational techniques. The book includes five selected papers from BIRTE 2015; five selected papers from BIRTE 2016; and three selected papers from BIRTE 2017.


Book Synopsis Real-Time Business Intelligence and Analytics by : Malu Castellanos

Download or read book Real-Time Business Intelligence and Analytics written by Malu Castellanos and published by Springer Nature. This book was released on 2019-10-10 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed conference proceedings of the BIRTE workshops listed below, which were held in in conjunction with VLDB, the International Conference on Very Large Data Bases: 9th International Workshop on Business Intelligence for the Real-Time Enterprise, BIRTE 2015, held in Kohala Coast, Hawaii, in August 2015, 10th International Workshop on Enabling Real-Time Business Intelligence, BIRTE 2016, held in New Delhi, India, in September 2016, 11th International Workshop on Real-Time Business Intelligence and Analytics, BIRTE 2017, held in Munich, Germany, in August 2017. The BIRTE workshop series provides a forum for the discussion and advancement of the science and engineering enabling real-time business intelligence and the novel applications that build on these foundational techniques. The book includes five selected papers from BIRTE 2015; five selected papers from BIRTE 2016; and three selected papers from BIRTE 2017.

Heterogeneous Data Management, Polystores, and Analytics for Healthcare

Heterogeneous Data Management, Polystores, and Analytics for Healthcare

Author: Vijay Gadepally

Publisher: Springer

Published: 2019-03-21

Total Pages: 175

ISBN-13: 3030141772

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This book constitutes the refereed post-conference proceedings of International Workshops: Polystores and other Systems for Heterogeneous Data, Poly 2018, and Data Management and Analytics for Medicine and Healthcare, DMAH 2018, in Rio de Janeiro, Brazil, in August 2018, held in conjunction with the 44th International Conference on Very Large Data Bases, VLDB 2018. The 11 regular papers presented together with 2 invited papers and 1 abstract of a keynote talk were carefully reviewed and selected from 16 initial submissions. The Poly 2018 Workshop focus on growing a larger and more diverse research agenda around data system solutions for heterogeneous data. The DMAH 2018 Workshop aims to foster exchange of information and discussions on innovative data management and analytics technologies.


Book Synopsis Heterogeneous Data Management, Polystores, and Analytics for Healthcare by : Vijay Gadepally

Download or read book Heterogeneous Data Management, Polystores, and Analytics for Healthcare written by Vijay Gadepally and published by Springer. This book was released on 2019-03-21 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed post-conference proceedings of International Workshops: Polystores and other Systems for Heterogeneous Data, Poly 2018, and Data Management and Analytics for Medicine and Healthcare, DMAH 2018, in Rio de Janeiro, Brazil, in August 2018, held in conjunction with the 44th International Conference on Very Large Data Bases, VLDB 2018. The 11 regular papers presented together with 2 invited papers and 1 abstract of a keynote talk were carefully reviewed and selected from 16 initial submissions. The Poly 2018 Workshop focus on growing a larger and more diverse research agenda around data system solutions for heterogeneous data. The DMAH 2018 Workshop aims to foster exchange of information and discussions on innovative data management and analytics technologies.

Data Analysis for the Life Sciences with R

Data Analysis for the Life Sciences with R

Author: Rafael A. Irizarry

Publisher: CRC Press

Published: 2016-10-04

Total Pages: 461

ISBN-13: 1498775861

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This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.


Book Synopsis Data Analysis for the Life Sciences with R by : Rafael A. Irizarry

Download or read book Data Analysis for the Life Sciences with R written by Rafael A. Irizarry and published by CRC Press. This book was released on 2016-10-04 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

The Digital Patient

The Digital Patient

Author: C. D. Combs

Publisher: John Wiley & Sons

Published: 2015-12-11

Total Pages: 336

ISBN-13: 1118952766

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A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.


Book Synopsis The Digital Patient by : C. D. Combs

Download or read book The Digital Patient written by C. D. Combs and published by John Wiley & Sons. This book was released on 2015-12-11 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.

High Performance Computing

High Performance Computing

Author: Ponnuswamy Sadayappan

Publisher: Springer Nature

Published: 2020-06-15

Total Pages: 564

ISBN-13: 3030507432

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This book constitutes the refereed proceedings of the 35th International Conference on High Performance Computing, ISC High Performance 2020, held in Frankfurt/Main, Germany, in June 2020.* The 27 revised full papers presented were carefully reviewed and selected from 87 submissions. The papers cover a broad range of topics such as architectures, networks & infrastructure; artificial intelligence and machine learning; data, storage & visualization; emerging technologies; HPC algorithms; HPC applications; performance modeling & measurement; programming models & systems software. *The conference was held virtually due to the COVID-19 pandemic. Chapters "Scalable Hierarchical Aggregation and Reduction Protocol (SHARP) Streaming-Aggregation Hardware Design and Evaluation", "Solving Acoustic Boundary Integral Equations Using High Performance Tile Low-Rank LU Factorization", "Scaling Genomics Data Processing with Memory-Driven Computing to Accelerate Computational Biology", "Footprint-Aware Power Capping for Hybrid Memory Based Systems", and "Pattern-Aware Staging for Hybrid Memory Systems" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.


Book Synopsis High Performance Computing by : Ponnuswamy Sadayappan

Download or read book High Performance Computing written by Ponnuswamy Sadayappan and published by Springer Nature. This book was released on 2020-06-15 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 35th International Conference on High Performance Computing, ISC High Performance 2020, held in Frankfurt/Main, Germany, in June 2020.* The 27 revised full papers presented were carefully reviewed and selected from 87 submissions. The papers cover a broad range of topics such as architectures, networks & infrastructure; artificial intelligence and machine learning; data, storage & visualization; emerging technologies; HPC algorithms; HPC applications; performance modeling & measurement; programming models & systems software. *The conference was held virtually due to the COVID-19 pandemic. Chapters "Scalable Hierarchical Aggregation and Reduction Protocol (SHARP) Streaming-Aggregation Hardware Design and Evaluation", "Solving Acoustic Boundary Integral Equations Using High Performance Tile Low-Rank LU Factorization", "Scaling Genomics Data Processing with Memory-Driven Computing to Accelerate Computational Biology", "Footprint-Aware Power Capping for Hybrid Memory Based Systems", and "Pattern-Aware Staging for Hybrid Memory Systems" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Big Data Management and Processing

Big Data Management and Processing

Author: Kuan-Ching Li

Publisher: CRC Press

Published: 2017-05-19

Total Pages: 489

ISBN-13: 1498768083

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From the Foreword: "Big Data Management and Processing is [a] state-of-the-art book that deals with a wide range of topical themes in the field of Big Data. The book, which probes many issues related to this exciting and rapidly growing field, covers processing, management, analytics, and applications... [It] is a very valuable addition to the literature. It will serve as a source of up-to-date research in this continuously developing area. The book also provides an opportunity for researchers to explore the use of advanced computing technologies and their impact on enhancing our capabilities to conduct more sophisticated studies." ---Sartaj Sahni, University of Florida, USA "Big Data Management and Processing covers the latest Big Data research results in processing, analytics, management and applications. Both fundamental insights and representative applications are provided. This book is a timely and valuable resource for students, researchers and seasoned practitioners in Big Data fields. --Hai Jin, Huazhong University of Science and Technology, China Big Data Management and Processing explores a range of big data related issues and their impact on the design of new computing systems. The twenty-one chapters were carefully selected and feature contributions from several outstanding researchers. The book endeavors to strike a balance between theoretical and practical coverage of innovative problem solving techniques for a range of platforms. It serves as a repository of paradigms, technologies, and applications that target different facets of big data computing systems. The first part of the book explores energy and resource management issues, as well as legal compliance and quality management for Big Data. It covers In-Memory computing and In-Memory data grids, as well as co-scheduling for high performance computing applications. The second part of the book includes comprehensive coverage of Hadoop and Spark, along with security, privacy, and trust challenges and solutions. The latter part of the book covers mining and clustering in Big Data, and includes applications in genomics, hospital big data processing, and vehicular cloud computing. The book also analyzes funding for Big Data projects.


Book Synopsis Big Data Management and Processing by : Kuan-Ching Li

Download or read book Big Data Management and Processing written by Kuan-Ching Li and published by CRC Press. This book was released on 2017-05-19 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Foreword: "Big Data Management and Processing is [a] state-of-the-art book that deals with a wide range of topical themes in the field of Big Data. The book, which probes many issues related to this exciting and rapidly growing field, covers processing, management, analytics, and applications... [It] is a very valuable addition to the literature. It will serve as a source of up-to-date research in this continuously developing area. The book also provides an opportunity for researchers to explore the use of advanced computing technologies and their impact on enhancing our capabilities to conduct more sophisticated studies." ---Sartaj Sahni, University of Florida, USA "Big Data Management and Processing covers the latest Big Data research results in processing, analytics, management and applications. Both fundamental insights and representative applications are provided. This book is a timely and valuable resource for students, researchers and seasoned practitioners in Big Data fields. --Hai Jin, Huazhong University of Science and Technology, China Big Data Management and Processing explores a range of big data related issues and their impact on the design of new computing systems. The twenty-one chapters were carefully selected and feature contributions from several outstanding researchers. The book endeavors to strike a balance between theoretical and practical coverage of innovative problem solving techniques for a range of platforms. It serves as a repository of paradigms, technologies, and applications that target different facets of big data computing systems. The first part of the book explores energy and resource management issues, as well as legal compliance and quality management for Big Data. It covers In-Memory computing and In-Memory data grids, as well as co-scheduling for high performance computing applications. The second part of the book includes comprehensive coverage of Hadoop and Spark, along with security, privacy, and trust challenges and solutions. The latter part of the book covers mining and clustering in Big Data, and includes applications in genomics, hospital big data processing, and vehicular cloud computing. The book also analyzes funding for Big Data projects.

Smart Maintenance for Human–Robot Interaction

Smart Maintenance for Human–Robot Interaction

Author: Bo Xing

Publisher: Springer

Published: 2017-09-08

Total Pages: 305

ISBN-13: 3319674803

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This self-contained book, written by active researchers, presents up-to-date information on smart maintenance strategies for human–robot interaction (HRI) and the associated applications of novel search algorithms in a single volume, eliminating the need to consult scattered resources. Unlike other books, it addresses maintaining a smart HRI from three dimensions, namely, hardware, cyberware, and hybrid-asset management, covering problems encountered in each through a wide variety of representative examples and elaborated illustrations. Further, the diverse mathematical models and intelligent systems constructions make the book highly practical. It enables readers interested in maintenance, robotics, and intelligent systems but perplexed by myriads of interrelated issues to grasp basic methodologies. At the same time, the referenced literature can be used as a roadmap for conducting deeper researches.


Book Synopsis Smart Maintenance for Human–Robot Interaction by : Bo Xing

Download or read book Smart Maintenance for Human–Robot Interaction written by Bo Xing and published by Springer. This book was released on 2017-09-08 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This self-contained book, written by active researchers, presents up-to-date information on smart maintenance strategies for human–robot interaction (HRI) and the associated applications of novel search algorithms in a single volume, eliminating the need to consult scattered resources. Unlike other books, it addresses maintaining a smart HRI from three dimensions, namely, hardware, cyberware, and hybrid-asset management, covering problems encountered in each through a wide variety of representative examples and elaborated illustrations. Further, the diverse mathematical models and intelligent systems constructions make the book highly practical. It enables readers interested in maintenance, robotics, and intelligent systems but perplexed by myriads of interrelated issues to grasp basic methodologies. At the same time, the referenced literature can be used as a roadmap for conducting deeper researches.