HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design

HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design

Author: Marc H V Van Regenmortel

Publisher: Springer Nature

Published: 2019-11-26

Total Pages: 364

ISBN-13: 3030324591

DOWNLOAD EBOOK

This book gathers a series of pivotal papers on the development of an HIV/AIDS vaccine published in the last two decades. Accompanied by extensive comments putting the material into an up-to-date context, all three parts of the book offer a broad overview of the numerous unsuccessful attempts made in recent years to develop a preventive HIV vaccine. Providing a detailed review and analysis of studies published from 1998 to the present day, it examines the likely reasons for the failure to develop an HIV vaccine despite multi-million dollar investments.


Book Synopsis HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design by : Marc H V Van Regenmortel

Download or read book HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design written by Marc H V Van Regenmortel and published by Springer Nature. This book was released on 2019-11-26 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers a series of pivotal papers on the development of an HIV/AIDS vaccine published in the last two decades. Accompanied by extensive comments putting the material into an up-to-date context, all three parts of the book offer a broad overview of the numerous unsuccessful attempts made in recent years to develop a preventive HIV vaccine. Providing a detailed review and analysis of studies published from 1998 to the present day, it examines the likely reasons for the failure to develop an HIV vaccine despite multi-million dollar investments.


Reassessing HIV Vaccine Design and Approaches

Reassessing HIV Vaccine Design and Approaches

Author: Omar Bagasra

Publisher:

Published: 2013

Total Pages: 288

ISBN-13: 9781624175381

DOWNLOAD EBOOK

Why do we not have a vaccine for HIV? What are we doing wrong? Every HIV vaccine has failed so far, and public opinion is turning pessimistic against the scientific community. HIV vaccine efforts need a major shift in strategy. They require a better understanding of the immunological mechanisms that prevent African primates from getting AIDS. None of the 40 species of African primates, including chimpanzees and gorillas, get AIDS, even though all of them carry HIV-like viruses in their bodies. Why are they naturally vaccinated, while all of the man-made vaccines against HIV have failed miserably? This book offers intriguing new possibilities for the nature of human immunity, and the development of an effective AIDS vaccine. It is also a provocative treatise on the origin, evolution, and etiology of several forms of immune systems that is supported by a wealth of peer-reviewed scientific references. The compelling ideas presented in this study should have an important bearing on HIV vaccine development. It is a must read for anyone interested in the development of a safe AIDS vaccine, and for individuals interested in human immunity generally.


Book Synopsis Reassessing HIV Vaccine Design and Approaches by : Omar Bagasra

Download or read book Reassessing HIV Vaccine Design and Approaches written by Omar Bagasra and published by . This book was released on 2013 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do we not have a vaccine for HIV? What are we doing wrong? Every HIV vaccine has failed so far, and public opinion is turning pessimistic against the scientific community. HIV vaccine efforts need a major shift in strategy. They require a better understanding of the immunological mechanisms that prevent African primates from getting AIDS. None of the 40 species of African primates, including chimpanzees and gorillas, get AIDS, even though all of them carry HIV-like viruses in their bodies. Why are they naturally vaccinated, while all of the man-made vaccines against HIV have failed miserably? This book offers intriguing new possibilities for the nature of human immunity, and the development of an effective AIDS vaccine. It is also a provocative treatise on the origin, evolution, and etiology of several forms of immune systems that is supported by a wealth of peer-reviewed scientific references. The compelling ideas presented in this study should have an important bearing on HIV vaccine development. It is a must read for anyone interested in the development of a safe AIDS vaccine, and for individuals interested in human immunity generally.


Bioinformatics Tools and Big Data Analytics for Patient Care

Bioinformatics Tools and Big Data Analytics for Patient Care

Author: Rishabha Malviya

Publisher: CRC Press

Published: 2022-08-31

Total Pages: 357

ISBN-13: 1000638901

DOWNLOAD EBOOK

Nowadays, raw biological data can be easily stored as databases in computers but extracting the required information is the real challenge for researchers. For this reason, bioinformatics tools perform a vital role in extracting and analyzing information from databases. Bioinformatics Tools and Big Data Analytics for Patient describes the applications of bioinformatics, data management, and computational techniques in clinical studies and drug discovery for patient care. The book gives details about the recent developments in the fields of artificial intelligence, cloud computing, and data analytics. It highlights the advances in computational techniques used to perform intelligent medical tasks. Features: Presents recent developments in the fields of artificial intelligence, cloud computing, and data analytics for improved patient care. Describes the applications of bioinformatics, data management, and computational techniques in clinical studies and drug discovery. Summarizes several strategies, analyses, and optimization methods for patient healthcare. Focuses on drug discovery and development by cloud computing and data-driven research The targeted audience comprises academics, research scholars, healthcare professionals, hospital managers, pharmaceutical chemists, the biomedical industry, software engineers, and IT professionals.


Book Synopsis Bioinformatics Tools and Big Data Analytics for Patient Care by : Rishabha Malviya

Download or read book Bioinformatics Tools and Big Data Analytics for Patient Care written by Rishabha Malviya and published by CRC Press. This book was released on 2022-08-31 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, raw biological data can be easily stored as databases in computers but extracting the required information is the real challenge for researchers. For this reason, bioinformatics tools perform a vital role in extracting and analyzing information from databases. Bioinformatics Tools and Big Data Analytics for Patient describes the applications of bioinformatics, data management, and computational techniques in clinical studies and drug discovery for patient care. The book gives details about the recent developments in the fields of artificial intelligence, cloud computing, and data analytics. It highlights the advances in computational techniques used to perform intelligent medical tasks. Features: Presents recent developments in the fields of artificial intelligence, cloud computing, and data analytics for improved patient care. Describes the applications of bioinformatics, data management, and computational techniques in clinical studies and drug discovery. Summarizes several strategies, analyses, and optimization methods for patient healthcare. Focuses on drug discovery and development by cloud computing and data-driven research The targeted audience comprises academics, research scholars, healthcare professionals, hospital managers, pharmaceutical chemists, the biomedical industry, software engineers, and IT professionals.


System Vaccinology

System Vaccinology

Author: Vijay Kumar Prajapati

Publisher: Academic Press

Published: 2022-08-20

Total Pages: 438

ISBN-13: 032389786X

DOWNLOAD EBOOK

Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters. Provides in-depth knowledge of vaccine history Covers the development of system vaccinology and their applications revolutionize the vaccine discovery Gives insights to the development of new strategies to design efficacious and safe vaccine molecule Provides a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials Highlights the importance of differential miRNA expression, microbiome after vaccination for human health Serves the need of students and researcher for applying computational tools and quick designing of potential molecule which may be proposed for vaccine trial Take the decisions to perform the kind of experiments for assessment of vaccine immunogenicity Aims to understand disease pathogenesis and host responses to infection and vaccination Offers a seamless continuum of scientific discovery and vaccine invention


Book Synopsis System Vaccinology by : Vijay Kumar Prajapati

Download or read book System Vaccinology written by Vijay Kumar Prajapati and published by Academic Press. This book was released on 2022-08-20 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters. Provides in-depth knowledge of vaccine history Covers the development of system vaccinology and their applications revolutionize the vaccine discovery Gives insights to the development of new strategies to design efficacious and safe vaccine molecule Provides a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials Highlights the importance of differential miRNA expression, microbiome after vaccination for human health Serves the need of students and researcher for applying computational tools and quick designing of potential molecule which may be proposed for vaccine trial Take the decisions to perform the kind of experiments for assessment of vaccine immunogenicity Aims to understand disease pathogenesis and host responses to infection and vaccination Offers a seamless continuum of scientific discovery and vaccine invention


Separation Techniques Applied to Omics Sciences

Separation Techniques Applied to Omics Sciences

Author: Ana Valéria Colnaghi Simionato

Publisher: Springer Nature

Published: 2021-10-09

Total Pages: 277

ISBN-13: 3030772527

DOWNLOAD EBOOK

This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses and unique aspects in each case. This volume intends to offer wide ranging options available to researchers on omics sciences, and how to integrate them in order to achieve the comprehension of a biological system as a whole. Omic sciences have been of ultimate importance to comprehend the complex biochemical reactions and related events that occurs upon a biological system. The classical central dogma of molecular biology, which states that genetic information flows unidirectionally from DNA to RNA and then to proteins, has been gradually replaced by the systems biology approach. This book presents a multidisciplinary approach that explains the biological system as a whole, where the entire organism is influenced by a variety of internal events as well as by the environment, showing that each level of the biological information flux may influence the previous or the subsequent one.


Book Synopsis Separation Techniques Applied to Omics Sciences by : Ana Valéria Colnaghi Simionato

Download or read book Separation Techniques Applied to Omics Sciences written by Ana Valéria Colnaghi Simionato and published by Springer Nature. This book was released on 2021-10-09 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses and unique aspects in each case. This volume intends to offer wide ranging options available to researchers on omics sciences, and how to integrate them in order to achieve the comprehension of a biological system as a whole. Omic sciences have been of ultimate importance to comprehend the complex biochemical reactions and related events that occurs upon a biological system. The classical central dogma of molecular biology, which states that genetic information flows unidirectionally from DNA to RNA and then to proteins, has been gradually replaced by the systems biology approach. This book presents a multidisciplinary approach that explains the biological system as a whole, where the entire organism is influenced by a variety of internal events as well as by the environment, showing that each level of the biological information flux may influence the previous or the subsequent one.


Epitope mapped vaccines and diagnostics for emerging pathogens

Epitope mapped vaccines and diagnostics for emerging pathogens

Author: Tarek A. Ahmad

Publisher: Frontiers Media SA

Published: 2023-01-31

Total Pages: 277

ISBN-13: 2832513018

DOWNLOAD EBOOK


Book Synopsis Epitope mapped vaccines and diagnostics for emerging pathogens by : Tarek A. Ahmad

Download or read book Epitope mapped vaccines and diagnostics for emerging pathogens written by Tarek A. Ahmad and published by Frontiers Media SA. This book was released on 2023-01-31 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Bioinformatics Research and Applications

Bioinformatics Research and Applications

Author: Xuan Guo

Publisher: Springer Nature

Published: 2023-11-08

Total Pages: 567

ISBN-13: 9819970741

DOWNLOAD EBOOK

This book constitutes the refereed proceedings of the 19th International Symposium on Bioinformatics Research and Applications, ISBRA 2023, held in Wrocław, Poland, during October 9–12, 2023. The 28 full papers and 16 short papers included in this book were carefully reviewed and selected from 89 submissions. They were organized in topical sections as follows: reconciling inconsistent molecular structures from biochemical databases; radiology report generation via visual recalibration and context gating-aware; sequence-based nanobody-antigen binding prediction; and hist2Vec: kernel-based embeddings for biological sequence classification.


Book Synopsis Bioinformatics Research and Applications by : Xuan Guo

Download or read book Bioinformatics Research and Applications written by Xuan Guo and published by Springer Nature. This book was released on 2023-11-08 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 19th International Symposium on Bioinformatics Research and Applications, ISBRA 2023, held in Wrocław, Poland, during October 9–12, 2023. The 28 full papers and 16 short papers included in this book were carefully reviewed and selected from 89 submissions. They were organized in topical sections as follows: reconciling inconsistent molecular structures from biochemical databases; radiology report generation via visual recalibration and context gating-aware; sequence-based nanobody-antigen binding prediction; and hist2Vec: kernel-based embeddings for biological sequence classification.


Vaccine Design

Vaccine Design

Author: Rino Rappuoli

Publisher: Caister Academic Press Limited

Published: 2011

Total Pages: 0

ISBN-13: 9781904455745

DOWNLOAD EBOOK

In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies.


Book Synopsis Vaccine Design by : Rino Rappuoli

Download or read book Vaccine Design written by Rino Rappuoli and published by Caister Academic Press Limited. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies.


Immunopathogenesis of HIV Infection

Immunopathogenesis of HIV Infection

Author: Anthony S. Fauci

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 159

ISBN-13: 3642608671

DOWNLOAD EBOOK

During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies.


Book Synopsis Immunopathogenesis of HIV Infection by : Anthony S. Fauci

Download or read book Immunopathogenesis of HIV Infection written by Anthony S. Fauci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies.


Mucosal Vaccines

Mucosal Vaccines

Author: Hiroshi Kiyono

Publisher: Elsevier

Published: 1996-10-23

Total Pages: 501

ISBN-13: 0080537057

DOWNLOAD EBOOK

This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization


Book Synopsis Mucosal Vaccines by : Hiroshi Kiyono

Download or read book Mucosal Vaccines written by Hiroshi Kiyono and published by Elsevier. This book was released on 1996-10-23 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization