Hyperbranched Polydendrons

Hyperbranched Polydendrons

Author: Fiona L. Hatton

Publisher: Springer

Published: 2015-05-18

Total Pages: 279

ISBN-13: 3319187538

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This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to combine the benefits of dendrimers with the simplicity of conventional polymerisation. There is no other available literature on these remarkable materials, dubbed hyperbranched polydendrons, due to their novelty. The new materials were shown to have very high molecular weights (>1,000,000 g/mol), exceptional self-assembly and encapsulation behaviour and unparalleled functionalisation capabilities, and were studied pharmacologically to determine their potential as oral nanomedicine candidates. The detailed investigation of the chemical variables involved in synthesising hyperbranched polydendrons has shown that their self-assembly and pharmacological behaviour can be turned on and off and fine-tuned by altering the composition of the materials. The permeation of the self-assembled particles through model gut epithelium suggests the potential for oral dosing of drug loaded nanomedicines that result in circulating nanoparticles – a research goal that is currently being pursued by several groups around the globe.


Book Synopsis Hyperbranched Polydendrons by : Fiona L. Hatton

Download or read book Hyperbranched Polydendrons written by Fiona L. Hatton and published by Springer. This book was released on 2015-05-18 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to combine the benefits of dendrimers with the simplicity of conventional polymerisation. There is no other available literature on these remarkable materials, dubbed hyperbranched polydendrons, due to their novelty. The new materials were shown to have very high molecular weights (>1,000,000 g/mol), exceptional self-assembly and encapsulation behaviour and unparalleled functionalisation capabilities, and were studied pharmacologically to determine their potential as oral nanomedicine candidates. The detailed investigation of the chemical variables involved in synthesising hyperbranched polydendrons has shown that their self-assembly and pharmacological behaviour can be turned on and off and fine-tuned by altering the composition of the materials. The permeation of the self-assembled particles through model gut epithelium suggests the potential for oral dosing of drug loaded nanomedicines that result in circulating nanoparticles – a research goal that is currently being pursued by several groups around the globe.

Hyperbranched Polydendrons

Hyperbranched Polydendrons

Author: Fiona L. Hatton

Publisher:

Published: 2015

Total Pages:

ISBN-13: 9783319187549

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This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to combine the benefits of dendrimers with the simplicity of conventional polymerisation. There is no other available literature on these remarkable materials, dubbed hyperbranched polydendrons, due to their novelty. The new materials were shown to have very high molecular weights (>1,000,000 g/mol), exceptional self-assembly and encapsulation behaviour and unparalleled functionalisation capabilities, and were studied pharmacologically to determine their potential as oral nanomedicine candidates. The detailed investigation of the chemical variables involved in synthesising hyperbranched polydendrons has shown that their self-assembly and pharmacological behaviour can be turned on and off and fine-tuned by altering the composition of the materials. The permeation of the self-assembled particles through model gut epithelium suggests the potential for oral dosing of drug loaded nanomedicines that result in circulating nanoparticles - a research goal that is currently being pursued by several groups around the globe.


Book Synopsis Hyperbranched Polydendrons by : Fiona L. Hatton

Download or read book Hyperbranched Polydendrons written by Fiona L. Hatton and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis outlines the first synthesis of a new complex branched polymer architecture that aims to combine the benefits of dendrimers with the simplicity of conventional polymerisation. There is no other available literature on these remarkable materials, dubbed hyperbranched polydendrons, due to their novelty. The new materials were shown to have very high molecular weights (>1,000,000 g/mol), exceptional self-assembly and encapsulation behaviour and unparalleled functionalisation capabilities, and were studied pharmacologically to determine their potential as oral nanomedicine candidates. The detailed investigation of the chemical variables involved in synthesising hyperbranched polydendrons has shown that their self-assembly and pharmacological behaviour can be turned on and off and fine-tuned by altering the composition of the materials. The permeation of the self-assembled particles through model gut epithelium suggests the potential for oral dosing of drug loaded nanomedicines that result in circulating nanoparticles - a research goal that is currently being pursued by several groups around the globe.

Star and Hyperbranched Polymers

Star and Hyperbranched Polymers

Author: Munmaya Mishra

Publisher: CRC Press

Published: 1999-05-25

Total Pages: 368

ISBN-13: 9780824719869

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Synthesizing the raw data needed for a wide variety of industrial applications, this work supplies up-to-date advanced in research on star, hyperbranched and dendritic polymers. It provides detailed descriptions of the size and shape of the molecules that make up these polymers, as well as their biological advances, low viscosity in solution and substrate-holding properties.


Book Synopsis Star and Hyperbranched Polymers by : Munmaya Mishra

Download or read book Star and Hyperbranched Polymers written by Munmaya Mishra and published by CRC Press. This book was released on 1999-05-25 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizing the raw data needed for a wide variety of industrial applications, this work supplies up-to-date advanced in research on star, hyperbranched and dendritic polymers. It provides detailed descriptions of the size and shape of the molecules that make up these polymers, as well as their biological advances, low viscosity in solution and substrate-holding properties.

Dendrimer Chemistry

Dendrimer Chemistry

Author: Michael Malkoch

Publisher: Royal Society of Chemistry

Published: 2020

Total Pages: 327

ISBN-13: 1788011325

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An overview of the latest advances in the synthesis, characterization and applications of dendrimers and other complex dendritic architectures.


Book Synopsis Dendrimer Chemistry by : Michael Malkoch

Download or read book Dendrimer Chemistry written by Michael Malkoch and published by Royal Society of Chemistry. This book was released on 2020 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the latest advances in the synthesis, characterization and applications of dendrimers and other complex dendritic architectures.

Nanostructures for Novel Therapy

Nanostructures for Novel Therapy

Author: Denisa Ficai

Publisher: Elsevier

Published: 2017-02-25

Total Pages: 908

ISBN-13: 0323461484

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Nanostructures for Novel Therapy: Synthesis, Characterization and Applications focuses on the fabrication and characterization of therapeutic nanostructures, in particular, synthesis, design, and in vitro and in vivo therapeutic evaluation. The chapters provide a cogent overview of recent therapeutic applications of nanostructured materials that includes applications of nanostructured materials for wound healing in plastic surgery and stem cell therapy. The book explores the promise for more effective therapy through the use of nanostructured materials, while also assessing the challenges their use might pose from both an economic and medicinal point of view. This innovative look at how nanostructured materials are used in therapeutics will be of great benefit to researchers, providing a greater understanding of the different ways nanomaterials could improve medical treatment, along with a discussion of the obstacles that need to be overcome in order to guarantee widespread availability. Outlines how the characteristics of nanostructures made from different materials gives particular properties that can be successfully used in therapeutics Compares the properties of different nanostructures, allowing medicinal chemists and engineers to select which are most appropriate for their needs Highlights new uses of nanostructures within the therapeutic field, enabling the discovery of new, more effective drugs


Book Synopsis Nanostructures for Novel Therapy by : Denisa Ficai

Download or read book Nanostructures for Novel Therapy written by Denisa Ficai and published by Elsevier. This book was released on 2017-02-25 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Novel Therapy: Synthesis, Characterization and Applications focuses on the fabrication and characterization of therapeutic nanostructures, in particular, synthesis, design, and in vitro and in vivo therapeutic evaluation. The chapters provide a cogent overview of recent therapeutic applications of nanostructured materials that includes applications of nanostructured materials for wound healing in plastic surgery and stem cell therapy. The book explores the promise for more effective therapy through the use of nanostructured materials, while also assessing the challenges their use might pose from both an economic and medicinal point of view. This innovative look at how nanostructured materials are used in therapeutics will be of great benefit to researchers, providing a greater understanding of the different ways nanomaterials could improve medical treatment, along with a discussion of the obstacles that need to be overcome in order to guarantee widespread availability. Outlines how the characteristics of nanostructures made from different materials gives particular properties that can be successfully used in therapeutics Compares the properties of different nanostructures, allowing medicinal chemists and engineers to select which are most appropriate for their needs Highlights new uses of nanostructures within the therapeutic field, enabling the discovery of new, more effective drugs

Synthesis of Amphiphilic Hyperbranched Glyco-polydendrons for Potential Applications in Nanomedicine

Synthesis of Amphiphilic Hyperbranched Glyco-polydendrons for Potential Applications in Nanomedicine

Author: A. B. Dwyer

Publisher:

Published: 2016

Total Pages:

ISBN-13:

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Book Synopsis Synthesis of Amphiphilic Hyperbranched Glyco-polydendrons for Potential Applications in Nanomedicine by : A. B. Dwyer

Download or read book Synthesis of Amphiphilic Hyperbranched Glyco-polydendrons for Potential Applications in Nanomedicine written by A. B. Dwyer and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exploring Hyperbranched-polydendron Chemistry and Architecture for Nanomedicine Applications

Exploring Hyperbranched-polydendron Chemistry and Architecture for Nanomedicine Applications

Author: H. E. Rogers

Publisher:

Published: 2016

Total Pages:

ISBN-13:

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Book Synopsis Exploring Hyperbranched-polydendron Chemistry and Architecture for Nanomedicine Applications by : H. E. Rogers

Download or read book Exploring Hyperbranched-polydendron Chemistry and Architecture for Nanomedicine Applications written by H. E. Rogers and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dendrimer-Based Drug Delivery Systems

Dendrimer-Based Drug Delivery Systems

Author: Yiyun Cheng

Publisher: John Wiley & Sons

Published: 2012-05-23

Total Pages: 542

ISBN-13: 1118275225

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The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.


Book Synopsis Dendrimer-Based Drug Delivery Systems by : Yiyun Cheng

Download or read book Dendrimer-Based Drug Delivery Systems written by Yiyun Cheng and published by John Wiley & Sons. This book was released on 2012-05-23 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.

SPSJ ... Annual Meeting

SPSJ ... Annual Meeting

Author: Kōbunshi Gakkai (Japan)

Publisher:

Published: 2000

Total Pages: 832

ISBN-13:

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Book Synopsis SPSJ ... Annual Meeting by : Kōbunshi Gakkai (Japan)

Download or read book SPSJ ... Annual Meeting written by Kōbunshi Gakkai (Japan) and published by . This book was released on 2000 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polymer Preprints, Japan

Polymer Preprints, Japan

Author:

Publisher:

Published: 2000

Total Pages: 828

ISBN-13:

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Book Synopsis Polymer Preprints, Japan by :

Download or read book Polymer Preprints, Japan written by and published by . This book was released on 2000 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: