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Download or read book Idiotypes in Biology and Medicine written by and published by . This book was released on 1990 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Download or read book Idiotypes in Biology and Medicine written by and published by . This book was released on 1990 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Heinz Köhler
Publisher: Academic Press
Published: 2013-10-22
Total Pages: 469
ISBN-13: 1483269833
DOWNLOAD EBOOKIdiotypy in Biology and Medicine aims to serve the increasing interest and involvement in the practical aspects of idiotypy in biological systems. The concept of idiotypy has received wide recognition and interest far beyond the area of immunology. Experiments and interpretation of findings, reported here, clearly support the general nature of the idiotype concept in manipulating biological systems to correct pathological conditions or to improve the immune adaptation to environmental factors. The book is organized into three sections. Section 1 discusses original concepts of idiotypic manipulations. It reviews old and recent data important for the concept of an idiotype network and reports on attempts to deal with the T-cell receptor paradox; explains the immune system in terms of a circular idiotype network that can be demonstrated by sequential immunization; and emphasizes the need for restrictions in network interactions. Section 2 addresses the role and activity of idiotypic and antiidiotypic antibodies in the regulation of the immune system. Section 3 takes the issue of idiotype-antiidiotype out of the realm of the immune system and discusses it as a new principle to analyze and manipulate biological systems in general.
Download or read book Idiotypy in Biology and Medicine written by Heinz Köhler and published by Academic Press. This book was released on 2013-10-22 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Idiotypy in Biology and Medicine aims to serve the increasing interest and involvement in the practical aspects of idiotypy in biological systems. The concept of idiotypy has received wide recognition and interest far beyond the area of immunology. Experiments and interpretation of findings, reported here, clearly support the general nature of the idiotype concept in manipulating biological systems to correct pathological conditions or to improve the immune adaptation to environmental factors. The book is organized into three sections. Section 1 discusses original concepts of idiotypic manipulations. It reviews old and recent data important for the concept of an idiotype network and reports on attempts to deal with the T-cell receptor paradox; explains the immune system in terms of a circular idiotype network that can be demonstrated by sequential immunization; and emphasizes the need for restrictions in network interactions. Section 2 addresses the role and activity of idiotypic and antiidiotypic antibodies in the regulation of the immune system. Section 3 takes the issue of idiotype-antiidiotype out of the realm of the immune system and discusses it as a new principle to analyze and manipulate biological systems in general.
Author: Mark Greene
Publisher: Springer Science & Business Media
Published: 2013-11-11
Total Pages: 498
ISBN-13: 1468447394
DOWNLOAD EBOOKThe phenomenon of idiotypy was discovered almost thirty years ago, but it was only during the past decade that it attracted widespread interest and became the subject of numerous research investigations. From the outset, much of the interest in idiotypy was based on its implications with respect to the repertoire of antibodies. Kunkel showed, for example, that idiotypes associated with certain human myeloma or Bence-Jones proteins were present in normal human globulins at levels of less than one part per million. Also, Oudin's original definition of idiotypy implied that idiotypes could be uniquely associated with individual rabbits as well as with particular antigen-binding specificities. Such observations provided some of the earliest evidence for an extensive repertoire of immunoglobulin molecules. The implications of these findings have been amply confirmed by recent studies of protein struc ture and molecular genetics; many of these studies are reviewed in the present volume. It is known now that the diversity of antibodies is based on the presence of numerous V and L V H genes, on recombinatorial events involving D and] segments, on somatic mutations, and on processes involving deletion of DNA followed by repair with errors, including inser tions. Each of these parameters is capable of influencing the idiotype expressed by the final immunoglobulin product. Regulation of the immune response is another area in which idiotypy has significantly influenced modern immunology.
Download or read book The Biology of Idiotypes written by Mark Greene and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phenomenon of idiotypy was discovered almost thirty years ago, but it was only during the past decade that it attracted widespread interest and became the subject of numerous research investigations. From the outset, much of the interest in idiotypy was based on its implications with respect to the repertoire of antibodies. Kunkel showed, for example, that idiotypes associated with certain human myeloma or Bence-Jones proteins were present in normal human globulins at levels of less than one part per million. Also, Oudin's original definition of idiotypy implied that idiotypes could be uniquely associated with individual rabbits as well as with particular antigen-binding specificities. Such observations provided some of the earliest evidence for an extensive repertoire of immunoglobulin molecules. The implications of these findings have been amply confirmed by recent studies of protein struc ture and molecular genetics; many of these studies are reviewed in the present volume. It is known now that the diversity of antibodies is based on the presence of numerous V and L V H genes, on recombinatorial events involving D and] segments, on somatic mutations, and on processes involving deletion of DNA followed by repair with errors, including inser tions. Each of these parameters is capable of influencing the idiotype expressed by the final immunoglobulin product. Regulation of the immune response is another area in which idiotypy has significantly influenced modern immunology.
Download or read book Idiotypes in Biology and Medicine written by D.A. Carson and published by . This book was released on 1989 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Idiotype Networks in Biology and Medicine written by Albert Osterhaus and published by . This book was released on 1990 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunoglobulin Idiotypes written by Charles A. Janeway and published by . This book was released on 1981 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: D. Scott Linthicum
Publisher: Springer
Published: 2013-06-02
Total Pages: 322
ISBN-13: 9781461237358
DOWNLOAD EBOOKHere is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin action, thyroid cell function, the neurosciences, cardiology, virology, pharmacology, and reproduction.
Download or read book Anti-Idiotypes, Receptors, and Molecular Mimicry written by D. Scott Linthicum and published by Springer. This book was released on 2013-06-02 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin action, thyroid cell function, the neurosciences, cardiology, virology, pharmacology, and reproduction.
Author: Hilary Koprowski
Publisher:
Published: 1985-08-01
Total Pages: 156
ISBN-13: 9783642706769
DOWNLOAD EBOOKDownload or read book Images of Biologically Active Structures in the Immune System written by Hilary Koprowski and published by . This book was released on 1985-08-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author: Constantin A. Bona
Publisher: CRC Press
Published: 2018-01-18
Total Pages: 210
ISBN-13: 1351087134
DOWNLOAD EBOOKThe goal of this book is to present findings which are supportive of the concept that the words of the idiotype dictionary and likewise self-recognition are essential for communication between lymphocyte clones while some unfaithful (infidel) copies of the words contained in the idiotype dictionary perhaps play a role in the functional regulation of nonlymphoid cells.
Download or read book Biological Application of Anti-Idiotypes written by Constantin A. Bona and published by CRC Press. This book was released on 2018-01-18 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this book is to present findings which are supportive of the concept that the words of the idiotype dictionary and likewise self-recognition are essential for communication between lymphocyte clones while some unfaithful (infidel) copies of the words contained in the idiotype dictionary perhaps play a role in the functional regulation of nonlymphoid cells.
Author: Bruno Maresca
Publisher: Springer Science & Business Media
Published: 2013-06-29
Total Pages: 260
ISBN-13: 3642846254
DOWNLOAD EBOOKProceedings of the NATO Advanced Research Workshop on Molecular Biology and its Application to Medical Mycology, held at Taormina, Italy, January 6-8, 1992
Download or read book Molecular Biology and its Application to Medical Mycology written by Bruno Maresca and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop on Molecular Biology and its Application to Medical Mycology, held at Taormina, Italy, January 6-8, 1992