Impact of Polycystic Ovary, Metabolic Syndrome and Obesity on Women Health

Impact of Polycystic Ovary, Metabolic Syndrome and Obesity on Women Health

Author: Andrea R. Genazzani

Publisher: Springer Nature

Published: 2021-10-25

Total Pages: 227

ISBN-13: 303063650X

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This volume comprehensively focuses on polycystic ovary, metabolic syndrome and obesity and their impact on women’s health, reproduction and quality of life from adolescence to old age. PCOS is analyzed form the early origins - highlighting the importance of diagnosis, management and treatment starting from the high-risk period of adolescence - throughout infertility PCOS-related issues, pregnancy and menopause transition. All aspects of this syndrome are covered also in relation with endocrine and metabolic features that affects women’s health. This book is a very useful tool for gynecologists, endocrinologists, obstetricians, reproductive medicine and general practitioners and is an important resource for all physicians involved in women’s health.


Book Synopsis Impact of Polycystic Ovary, Metabolic Syndrome and Obesity on Women Health by : Andrea R. Genazzani

Download or read book Impact of Polycystic Ovary, Metabolic Syndrome and Obesity on Women Health written by Andrea R. Genazzani and published by Springer Nature. This book was released on 2021-10-25 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprehensively focuses on polycystic ovary, metabolic syndrome and obesity and their impact on women’s health, reproduction and quality of life from adolescence to old age. PCOS is analyzed form the early origins - highlighting the importance of diagnosis, management and treatment starting from the high-risk period of adolescence - throughout infertility PCOS-related issues, pregnancy and menopause transition. All aspects of this syndrome are covered also in relation with endocrine and metabolic features that affects women’s health. This book is a very useful tool for gynecologists, endocrinologists, obstetricians, reproductive medicine and general practitioners and is an important resource for all physicians involved in women’s health.


Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

Author: Andrea Dunaif

Publisher: Springer Science & Business Media

Published: 2008-01-12

Total Pages: 361

ISBN-13: 1597451088

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This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.


Book Synopsis Polycystic Ovary Syndrome by : Andrea Dunaif

Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.


Frontiers in Gynecological Endocrinology

Frontiers in Gynecological Endocrinology

Author: Andrea R. Genazzani

Publisher: Springer

Published: 2015-12-01

Total Pages: 207

ISBN-13: 3319238655

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This volume represents an up-to-date overview on ovarian functions and reproduction, providing the reader with the latest advances in gynecological endocrinology. It is published within the International Society of Gynecological Endocrinology (ISGE) Series, and is based on the 2015 International School of Gynecological and Reproductive Endocrinology Winter Course. The book covers a very wide range of topics with particular focus on ovulation and assisted reproduction, ovarian aging and fertility, and premature ovarian failure. The volume will be an invaluable tool for gynecologists, endocrinologists, obstetrician, and experts in women’s health.


Book Synopsis Frontiers in Gynecological Endocrinology by : Andrea R. Genazzani

Download or read book Frontiers in Gynecological Endocrinology written by Andrea R. Genazzani and published by Springer. This book was released on 2015-12-01 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents an up-to-date overview on ovarian functions and reproduction, providing the reader with the latest advances in gynecological endocrinology. It is published within the International Society of Gynecological Endocrinology (ISGE) Series, and is based on the 2015 International School of Gynecological and Reproductive Endocrinology Winter Course. The book covers a very wide range of topics with particular focus on ovulation and assisted reproduction, ovarian aging and fertility, and premature ovarian failure. The volume will be an invaluable tool for gynecologists, endocrinologists, obstetrician, and experts in women’s health.


Diagnosis and Management of Polycystic Ovary Syndrome

Diagnosis and Management of Polycystic Ovary Syndrome

Author: NADIR R. FARID

Publisher: Springer Science & Business Media

Published: 2009-02-27

Total Pages: 275

ISBN-13: 038709718X

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Diagnosis and Management of Polycystic Ovary Syndrome is a comprehensive clinical reference work for primary care physicians, internists, general endocrinologists, obstetricians, gynecologists and students. PCOS is a common but frequently misdiagnosed disease. Many symptoms can be alleviated by early intervention and effective management. Prominent endocrinologists are gathered to detail current research and treatment in this metabolic disorder, affecting a growing population. The chapters are comprehensive, providing cutting edge knowledge on pathogenesis, manifestations, diagnosis and treatment of PCOS. Each chapter will be concise concluding with cogent practice points. The variety of medical issues presenting in PCOS patients result in late referrals or in- appropriate advice. This title will be a tool in a further understanding of the metabolic and genetic basis of PCOS, while providing management strategies.


Book Synopsis Diagnosis and Management of Polycystic Ovary Syndrome by : NADIR R. FARID

Download or read book Diagnosis and Management of Polycystic Ovary Syndrome written by NADIR R. FARID and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Management of Polycystic Ovary Syndrome is a comprehensive clinical reference work for primary care physicians, internists, general endocrinologists, obstetricians, gynecologists and students. PCOS is a common but frequently misdiagnosed disease. Many symptoms can be alleviated by early intervention and effective management. Prominent endocrinologists are gathered to detail current research and treatment in this metabolic disorder, affecting a growing population. The chapters are comprehensive, providing cutting edge knowledge on pathogenesis, manifestations, diagnosis and treatment of PCOS. Each chapter will be concise concluding with cogent practice points. The variety of medical issues presenting in PCOS patients result in late referrals or in- appropriate advice. This title will be a tool in a further understanding of the metabolic and genetic basis of PCOS, while providing management strategies.


Obesity, Insulin Resistance and Polycystic Ovary Syndrome

Obesity, Insulin Resistance and Polycystic Ovary Syndrome

Author: Anju Elizabeth Joham

Publisher:

Published: 2014

Total Pages: 252

ISBN-13:

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Polycystic Ovary Syndrome (PCOS) affects 12 to 21% of Australian reproductive-aged women and is a major public health concern (1-5). Whilst reproductive features (anovulation, infertility) are prominent, PCOS also has major metabolic [obesity, metabolic syndrome, type 2 diabetes (T2DM), cardiovascular disease risk factors] and psychological features (6-8). Obesity is a major chronic disease, with rising prevalence and diverse health impacts. The interplay between PCOS and weight contributes to the long-term consequences of PCOS, but is not well understood. Women with PCOS demonstrate insulin resistance (IR), which leads to adverse health consequences, both independent of and exacerbated by obesity. Here, I explore the poorly understood interplay between PCOS, IR, metabolic complications and weight.My clinical research aims to assess prevalence and severity of IR in PCOS and explore novel markers of IR: Pigment Epithelium-Derived Factor (PEDF) and vitamin D. Women with PCOS were more insulin resistant than body mass index (BMI)-matched controls. IR was present in 75% of lean women with PCOS, 62% of overweight controls and 95% of overweight women with PCOS. IR was exacerbated by increased BMI. PEDF was not elevated in PCOS, was not associated with IR and was not reduced by exercise training, despite improved IR. It was mainly obesity related and is not a useful marker of IR. Despite similar adiposity, vitamin D levels were lower in overweight women with PCOS compared with overweight controls. Vitamin D was associated with IR in PCOS, but not in the non-PCOS group. PCOS is an insulin resistant state with intrinsic IR, exacerbated by lifestyle/obesity mediated extrinsic IR. Measurement of IR remains a challenge; novel simple markers of IR are needed. New interventions to manage IR, including potentially vitamin D, need to be studied.My epidemiological research examines the natural history of PCOS and the relationship between PCOS, weight and complications. Extensive data from the Australian Longitudinal Study on Women's Health (ALSWH) was analysed to explore the prevalence of PCOS, the impact of obesity and relationship to reproductive and metabolic complications. We found that weight, body mass index (BMI) and weight gain over 10 years was higher in women reporting PCOS compared to those not reporting PCOS. BMI was the key predictor of PCOS status. Women with PCOS reported less contraception use and higher rates of trying to conceive, higher rates of infertility and use of fertility treatment including ovulation induction, but not increased in-vitro fertilisation. Reported pregnancy loss was higher in PCOS (related to fertility treatment and BMI, but not PCOS per se). The number of children per woman was similar in PCOS and non-PCOS groups, albeit with higher rates of fertility treatment. After conception and delivery, high BMI was negatively correlated with breastfeeding, suggesting the need for greater lactation support for overweight women. PCOS alone does not appear to impact on breastfeeding. PCOS was associated with higher prevalence of gestational diabetes and T2DM, independent of BMI. This suggests that all women with PCOS should be screened pre-conception or early in pregnancy, during pregnancy and in non-pregnant states for gestational diabetes and T2DM. PCOS status was not associated with hypertension, however BMI was, highlighting the need for blood pressure monitoring in overweight and obese women.This thesis addresses key gaps in our understanding of the natural history of PCOS. It provides important insight into aetiology and natural history of PCOS and advances the area by providing greater understanding of the interplay between BMI and PCOS and related complications.


Book Synopsis Obesity, Insulin Resistance and Polycystic Ovary Syndrome by : Anju Elizabeth Joham

Download or read book Obesity, Insulin Resistance and Polycystic Ovary Syndrome written by Anju Elizabeth Joham and published by . This book was released on 2014 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polycystic Ovary Syndrome (PCOS) affects 12 to 21% of Australian reproductive-aged women and is a major public health concern (1-5). Whilst reproductive features (anovulation, infertility) are prominent, PCOS also has major metabolic [obesity, metabolic syndrome, type 2 diabetes (T2DM), cardiovascular disease risk factors] and psychological features (6-8). Obesity is a major chronic disease, with rising prevalence and diverse health impacts. The interplay between PCOS and weight contributes to the long-term consequences of PCOS, but is not well understood. Women with PCOS demonstrate insulin resistance (IR), which leads to adverse health consequences, both independent of and exacerbated by obesity. Here, I explore the poorly understood interplay between PCOS, IR, metabolic complications and weight.My clinical research aims to assess prevalence and severity of IR in PCOS and explore novel markers of IR: Pigment Epithelium-Derived Factor (PEDF) and vitamin D. Women with PCOS were more insulin resistant than body mass index (BMI)-matched controls. IR was present in 75% of lean women with PCOS, 62% of overweight controls and 95% of overweight women with PCOS. IR was exacerbated by increased BMI. PEDF was not elevated in PCOS, was not associated with IR and was not reduced by exercise training, despite improved IR. It was mainly obesity related and is not a useful marker of IR. Despite similar adiposity, vitamin D levels were lower in overweight women with PCOS compared with overweight controls. Vitamin D was associated with IR in PCOS, but not in the non-PCOS group. PCOS is an insulin resistant state with intrinsic IR, exacerbated by lifestyle/obesity mediated extrinsic IR. Measurement of IR remains a challenge; novel simple markers of IR are needed. New interventions to manage IR, including potentially vitamin D, need to be studied.My epidemiological research examines the natural history of PCOS and the relationship between PCOS, weight and complications. Extensive data from the Australian Longitudinal Study on Women's Health (ALSWH) was analysed to explore the prevalence of PCOS, the impact of obesity and relationship to reproductive and metabolic complications. We found that weight, body mass index (BMI) and weight gain over 10 years was higher in women reporting PCOS compared to those not reporting PCOS. BMI was the key predictor of PCOS status. Women with PCOS reported less contraception use and higher rates of trying to conceive, higher rates of infertility and use of fertility treatment including ovulation induction, but not increased in-vitro fertilisation. Reported pregnancy loss was higher in PCOS (related to fertility treatment and BMI, but not PCOS per se). The number of children per woman was similar in PCOS and non-PCOS groups, albeit with higher rates of fertility treatment. After conception and delivery, high BMI was negatively correlated with breastfeeding, suggesting the need for greater lactation support for overweight women. PCOS alone does not appear to impact on breastfeeding. PCOS was associated with higher prevalence of gestational diabetes and T2DM, independent of BMI. This suggests that all women with PCOS should be screened pre-conception or early in pregnancy, during pregnancy and in non-pregnant states for gestational diabetes and T2DM. PCOS status was not associated with hypertension, however BMI was, highlighting the need for blood pressure monitoring in overweight and obese women.This thesis addresses key gaps in our understanding of the natural history of PCOS. It provides important insight into aetiology and natural history of PCOS and advances the area by providing greater understanding of the interplay between BMI and PCOS and related complications.


Hyperandrogenism in Women

Hyperandrogenism in Women

Author: R. Pasquali

Publisher: Karger Medical and Scientific Publishers

Published: 2019-09-09

Total Pages: 201

ISBN-13: 3318064718

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Hyperandrogenism profoundly affects women’s lives from lowering self-esteem to changing cognition and affective motivation. The polycystic ovary syndrome (PCOS) is the most common androgen excess disorder worldwide. While it is not the focus of this book, some aspects are discussed. The aim of this book is to improve understanding of androgen excess and its impact on several conditions. Topics include development of adipose tissue in females, insulin sensitivity, congenital adrenal hyperplasia, and Cushing’s disease/syndrome. There is also a discussion of PCOS with emphasis on in utero origins and specific genetic and epigenetic factors. This book provides a wealth of relevant information for every endocrinologist and gynecologist who wants to broaden their knowledge of androgens in various conditions.


Book Synopsis Hyperandrogenism in Women by : R. Pasquali

Download or read book Hyperandrogenism in Women written by R. Pasquali and published by Karger Medical and Scientific Publishers. This book was released on 2019-09-09 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperandrogenism profoundly affects women’s lives from lowering self-esteem to changing cognition and affective motivation. The polycystic ovary syndrome (PCOS) is the most common androgen excess disorder worldwide. While it is not the focus of this book, some aspects are discussed. The aim of this book is to improve understanding of androgen excess and its impact on several conditions. Topics include development of adipose tissue in females, insulin sensitivity, congenital adrenal hyperplasia, and Cushing’s disease/syndrome. There is also a discussion of PCOS with emphasis on in utero origins and specific genetic and epigenetic factors. This book provides a wealth of relevant information for every endocrinologist and gynecologist who wants to broaden their knowledge of androgens in various conditions.


Contemporary Gynecologic Practice

Contemporary Gynecologic Practice

Author: Atef Darwish

Publisher: BoD – Books on Demand

Published: 2015-02-04

Total Pages: 246

ISBN-13: 953511736X

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Gynecology is frequently changing due to extensive implementation of high technology in both, the diagnosis and management of gynecologic problems. General gynecologists, gynecologic endocrinologists, infertility specialists, gynecologic endoscopists, and gynecologic oncologists will find attractive, new information in this book.


Book Synopsis Contemporary Gynecologic Practice by : Atef Darwish

Download or read book Contemporary Gynecologic Practice written by Atef Darwish and published by BoD – Books on Demand. This book was released on 2015-02-04 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gynecology is frequently changing due to extensive implementation of high technology in both, the diagnosis and management of gynecologic problems. General gynecologists, gynecologic endocrinologists, infertility specialists, gynecologic endoscopists, and gynecologic oncologists will find attractive, new information in this book.


Debatable Topics in PCOS Patients

Debatable Topics in PCOS Patients

Author: N.K. Agrawal

Publisher: BoD – Books on Demand

Published: 2018-02-14

Total Pages: 121

ISBN-13: 9535138111

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The book deliberates a wide range of the latest research issues on polycystic ovary syndrome (PCOS). The topics discussed include the diagnosis and management of PCOS, dwelling in more depth into the pathophysiology of the syndrome and its genetic and epigenetic basis. The book covers a contemplative discussion on the influence of changing lifestyle patterns on PCOS. The book also includes a number of chapters defining a detailed description of the associated morbidities of PCOS and its long-term sequelae. Since PCOS is quite prevalent globally, the book is also of great interest to the public. Providing detailed information suitable for patients and clinicians, it provides information about the various treatment regimens and screening recommendations for women having this condition.


Book Synopsis Debatable Topics in PCOS Patients by : N.K. Agrawal

Download or read book Debatable Topics in PCOS Patients written by N.K. Agrawal and published by BoD – Books on Demand. This book was released on 2018-02-14 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book deliberates a wide range of the latest research issues on polycystic ovary syndrome (PCOS). The topics discussed include the diagnosis and management of PCOS, dwelling in more depth into the pathophysiology of the syndrome and its genetic and epigenetic basis. The book covers a contemplative discussion on the influence of changing lifestyle patterns on PCOS. The book also includes a number of chapters defining a detailed description of the associated morbidities of PCOS and its long-term sequelae. Since PCOS is quite prevalent globally, the book is also of great interest to the public. Providing detailed information suitable for patients and clinicians, it provides information about the various treatment regimens and screening recommendations for women having this condition.


Leptin and Reproduction

Leptin and Reproduction

Author: Michael C. Henson

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 352

ISBN-13: 1461501571

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The isolation of leptin in 1994 and its characterization as a factor influencing appetite, energy balance, and adiposity, immediately thrust the polypeptide into the rapidly growing body of literature centered on the physiology of obesity. The growing clinical awareness of obesity as a major health risk in developed societies dovetailed perfectly with any of a number of roles that leptin might play in this abenant physiological condition. Almost unnoticed amidst the excitement generated by early leptin publications was the suggestion that the "fat hormone" might also regulate a wide range of systems and events important to reproduction, including pubertal development, gonadal endocrinology, fettility, and pregnancy. Recognizing this potential, a relatively small cadre of researchers began to examine leptin specifically as a reproductive hormone, thus creating a new and fertile field of investigation. Interest in this area has since gained momentum and an increased number of participants have now made significant contributions to our understanding of many leptin-related mechanisms that are relevant to reproductive biology. Leptin and Reproduction is the first major volume to specifically address leptin as a reproductive hormone and closely examines the advances made in the short time since this field of interest developed. Preeminent researchers ti'om many of the subdisciplines working within this area present a welcomed compendium of the wealth of related literature and voice novel interpretations of cun'ent advances.


Book Synopsis Leptin and Reproduction by : Michael C. Henson

Download or read book Leptin and Reproduction written by Michael C. Henson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The isolation of leptin in 1994 and its characterization as a factor influencing appetite, energy balance, and adiposity, immediately thrust the polypeptide into the rapidly growing body of literature centered on the physiology of obesity. The growing clinical awareness of obesity as a major health risk in developed societies dovetailed perfectly with any of a number of roles that leptin might play in this abenant physiological condition. Almost unnoticed amidst the excitement generated by early leptin publications was the suggestion that the "fat hormone" might also regulate a wide range of systems and events important to reproduction, including pubertal development, gonadal endocrinology, fettility, and pregnancy. Recognizing this potential, a relatively small cadre of researchers began to examine leptin specifically as a reproductive hormone, thus creating a new and fertile field of investigation. Interest in this area has since gained momentum and an increased number of participants have now made significant contributions to our understanding of many leptin-related mechanisms that are relevant to reproductive biology. Leptin and Reproduction is the first major volume to specifically address leptin as a reproductive hormone and closely examines the advances made in the short time since this field of interest developed. Preeminent researchers ti'om many of the subdisciplines working within this area present a welcomed compendium of the wealth of related literature and voice novel interpretations of cun'ent advances.


Clinical Gynecology

Clinical Gynecology

Author: Eric J. Bieber

Publisher: Cambridge University Press

Published: 2015-04-23

Total Pages: 1127

ISBN-13: 1107040396

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Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.


Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.