Influenza Vaccines for the Future

Influenza Vaccines for the Future

Author: Rino Rappuoli

Publisher: Springer Science & Business Media

Published: 2010-10-28

Total Pages: 447

ISBN-13: 3034602790

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The emergence of H5N1 avian influenza in 1997 and of the influenza A H1N1 of swine origin in 2009 calls for new, rapid and sustainable solutions for both seasonal and pandemic influenza viruses. During the last ten years, science and technology have made enormous progress, and we are now able to monitor in real time the genetics of viruses while they spread globally, to make more powerful vaccines using novel adjuvants, and to generate viruses in the laboratory using reverse genetics. This volume not only provides state-of-the-art information on the biology of influenza viruses and on influenza vaccines, but is also designed to be a resource to face the present H1N1 pandemic and to plan for long-term global and sustainable solutions.


Book Synopsis Influenza Vaccines for the Future by : Rino Rappuoli

Download or read book Influenza Vaccines for the Future written by Rino Rappuoli and published by Springer Science & Business Media. This book was released on 2010-10-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of H5N1 avian influenza in 1997 and of the influenza A H1N1 of swine origin in 2009 calls for new, rapid and sustainable solutions for both seasonal and pandemic influenza viruses. During the last ten years, science and technology have made enormous progress, and we are now able to monitor in real time the genetics of viruses while they spread globally, to make more powerful vaccines using novel adjuvants, and to generate viruses in the laboratory using reverse genetics. This volume not only provides state-of-the-art information on the biology of influenza viruses and on influenza vaccines, but is also designed to be a resource to face the present H1N1 pandemic and to plan for long-term global and sustainable solutions.


Influenza Vaccines for the Future

Influenza Vaccines for the Future

Author: Rino Rappuoli

Publisher: Birkhäuser

Published: 2009-08-29

Total Pages: 299

ISBN-13: 9783764394202

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The threat constituted by the multiple outbreaks of avian influenza during the last few years is urgently calling for the development of new influenza vaccines. Fortunately, a quantum leap in technology has revolutionized the study of influenza and the engineering of new vaccine strains by reverse genetics. This volume provides a historical background and state-of-the-art information about the recent advances in the biology of influenza and the design of new influenza vaccines.


Book Synopsis Influenza Vaccines for the Future by : Rino Rappuoli

Download or read book Influenza Vaccines for the Future written by Rino Rappuoli and published by Birkhäuser. This book was released on 2009-08-29 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: The threat constituted by the multiple outbreaks of avian influenza during the last few years is urgently calling for the development of new influenza vaccines. Fortunately, a quantum leap in technology has revolutionized the study of influenza and the engineering of new vaccine strains by reverse genetics. This volume provides a historical background and state-of-the-art information about the recent advances in the biology of influenza and the design of new influenza vaccines.


Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines

Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines

Author: National Academy of Medicine

Publisher: National Academies Press

Published: 2021-12-31

Total Pages:

ISBN-13: 9780309089159

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Influenza viruses, both seasonal and pandemic, have the potential to disrupt the health and well-being of populations around the world. The global response to the COVID-19 pandemic and prior public health emergencies of international concern illustrate the importance of global preparedness and coordination among governments, academia, scientists, policy makers, nongovernmental organizations, the private sector, and the public to address the threat of pandemic influenza. These health emergencies have revealed opportunities to enhance global vaccine infrastructure, manufacturing, distribution, and administration. Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines outlines key findings and recommendations to bolster vaccine distribution, manufacturing, and supply chains for future seasonal and pandemic influenza events. This report addresses the challenges of manufacturing and distributing vaccines for both seasonal and pandemic influenza, highlighting the critical components of vaccine manufacturing and distribution and offering recommendations that would address gaps in the current global vaccine infrastructure.


Book Synopsis Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines by : National Academy of Medicine

Download or read book Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines written by National Academy of Medicine and published by National Academies Press. This book was released on 2021-12-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Influenza viruses, both seasonal and pandemic, have the potential to disrupt the health and well-being of populations around the world. The global response to the COVID-19 pandemic and prior public health emergencies of international concern illustrate the importance of global preparedness and coordination among governments, academia, scientists, policy makers, nongovernmental organizations, the private sector, and the public to address the threat of pandemic influenza. These health emergencies have revealed opportunities to enhance global vaccine infrastructure, manufacturing, distribution, and administration. Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines outlines key findings and recommendations to bolster vaccine distribution, manufacturing, and supply chains for future seasonal and pandemic influenza events. This report addresses the challenges of manufacturing and distributing vaccines for both seasonal and pandemic influenza, highlighting the critical components of vaccine manufacturing and distribution and offering recommendations that would address gaps in the current global vaccine infrastructure.


Pandemic Influenza Vaccine Approaches: Current Status and Future Directions

Pandemic Influenza Vaccine Approaches: Current Status and Future Directions

Author: Rebecca Jane Cox

Publisher: Frontiers Media SA

Published: 2022-09-28

Total Pages: 156

ISBN-13: 2832501036

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Book Synopsis Pandemic Influenza Vaccine Approaches: Current Status and Future Directions by : Rebecca Jane Cox

Download or read book Pandemic Influenza Vaccine Approaches: Current Status and Future Directions written by Rebecca Jane Cox and published by Frontiers Media SA. This book was released on 2022-09-28 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The Vaccine Book

The Vaccine Book

Author: Barry R. Bloom

Publisher: Academic Press

Published: 2016-06-23

Total Pages: 664

ISBN-13: 012805400X

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The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy


Book Synopsis The Vaccine Book by : Barry R. Bloom

Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy


History of Vaccine Development

History of Vaccine Development

Author: Stanley A. Plotkin

Publisher: Springer Science & Business Media

Published: 2011-05-11

Total Pages: 352

ISBN-13: 1441913394

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Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.


Book Synopsis History of Vaccine Development by : Stanley A. Plotkin

Download or read book History of Vaccine Development written by Stanley A. Plotkin and published by Springer Science & Business Media. This book was released on 2011-05-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.


Vaccines for the 21st Century

Vaccines for the 21st Century

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-02-21

Total Pages: 472

ISBN-13: 0309174988

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Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.


Book Synopsis Vaccines for the 21st Century by : Institute of Medicine

Download or read book Vaccines for the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2001-02-21 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.


Adverse Effects of Vaccines

Adverse Effects of Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-04-26

Total Pages: 894

ISBN-13: 0309214351

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In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.


Book Synopsis Adverse Effects of Vaccines by : Institute of Medicine

Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.


Influenza and Public Health

Influenza and Public Health

Author: Jennifer Gunn

Publisher: Taylor & Francis

Published: 2010-09-23

Total Pages: 307

ISBN-13: 1136532080

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Major influenza pandemics pose a constant threat. As evidenced by recent H5N1 avian flu and novel H1N1, influenza outbreaks can come in close succession, yet differ in their transmission and impact. With accelerated levels of commercial and population mobility, new forms of flu virus can also spread across the globe with unprecedented speed. Responding quickly and adequately to each outbreak becomes imperative on the part of governments and global public health organizations, but the difficulties of doing so are legion. One tool for pandemic planning is analysis of responses to past pandemics that provide insight into productive ways forward. This book investigates past influenza pandemics in light of today's, so as to afford critical insights into possible transmission patterns, experiences, mistakes, and interventions. It explores several pandemics over the past century, from the infamous 1918 Spanish Influenza, the avian flu epidemic of 2003, and the novel H1N1 pandemic of 2009, to lesser-known outbreaks such as the 1889-90 influenza pandemic and the Hong Kong Flu of 1968. Contributors to the volume examine cases from a wide range of disciplines, including history, sociology, epidemiology, virology, geography, and public health, identifying patterns that cut across pandemics in order to guide contemporary responses to infectious outbreaks.


Book Synopsis Influenza and Public Health by : Jennifer Gunn

Download or read book Influenza and Public Health written by Jennifer Gunn and published by Taylor & Francis. This book was released on 2010-09-23 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major influenza pandemics pose a constant threat. As evidenced by recent H5N1 avian flu and novel H1N1, influenza outbreaks can come in close succession, yet differ in their transmission and impact. With accelerated levels of commercial and population mobility, new forms of flu virus can also spread across the globe with unprecedented speed. Responding quickly and adequately to each outbreak becomes imperative on the part of governments and global public health organizations, but the difficulties of doing so are legion. One tool for pandemic planning is analysis of responses to past pandemics that provide insight into productive ways forward. This book investigates past influenza pandemics in light of today's, so as to afford critical insights into possible transmission patterns, experiences, mistakes, and interventions. It explores several pandemics over the past century, from the infamous 1918 Spanish Influenza, the avian flu epidemic of 2003, and the novel H1N1 pandemic of 2009, to lesser-known outbreaks such as the 1889-90 influenza pandemic and the Hong Kong Flu of 1968. Contributors to the volume examine cases from a wide range of disciplines, including history, sociology, epidemiology, virology, geography, and public health, identifying patterns that cut across pandemics in order to guide contemporary responses to infectious outbreaks.


The 2009 H1N1 Influenza Vaccination Campaign

The 2009 H1N1 Influenza Vaccination Campaign

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2011-01-22

Total Pages: 140

ISBN-13: 0309160219

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The 2009 H1N1 vaccination campaign was one of the largest public health campaigns in U.S. history, vaccinating one-quarter of the population in the first three months. The Institute of Medicine held three workshops in Raleigh, NC; Austin, TX; and Seattle, WA to learn from participants' experiences during the campaign and improve future emergency vaccination programs.


Book Synopsis The 2009 H1N1 Influenza Vaccination Campaign by : Institute of Medicine

Download or read book The 2009 H1N1 Influenza Vaccination Campaign written by Institute of Medicine and published by National Academies Press. This book was released on 2011-01-22 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2009 H1N1 vaccination campaign was one of the largest public health campaigns in U.S. history, vaccinating one-quarter of the population in the first three months. The Institute of Medicine held three workshops in Raleigh, NC; Austin, TX; and Seattle, WA to learn from participants' experiences during the campaign and improve future emergency vaccination programs.