Inhaled Steroids in Asthma

Inhaled Steroids in Asthma

Author: Robert P. Schleimer

Publisher: CRC Press

Published: 2001-11-21

Total Pages: 760

ISBN-13: 0203908538

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This book sums up the mechanistic basis, current status, and future prospects of steroid inhalation as the cornerstone of prophylactic asthma therapy, identifying its kinetic basis-especially the essential airway selectivity-and including a historical account of inhaled glucocorticoid development. Makes connections among the underlying pharmacol


Book Synopsis Inhaled Steroids in Asthma by : Robert P. Schleimer

Download or read book Inhaled Steroids in Asthma written by Robert P. Schleimer and published by CRC Press. This book was released on 2001-11-21 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sums up the mechanistic basis, current status, and future prospects of steroid inhalation as the cornerstone of prophylactic asthma therapy, identifying its kinetic basis-especially the essential airway selectivity-and including a historical account of inhaled glucocorticoid development. Makes connections among the underlying pharmacol


New Drugs and Targets for Asthma and COPD

New Drugs and Targets for Asthma and COPD

Author: T.T. Hansel

Publisher: Karger Medical and Scientific Publishers

Published: 2010-08-31

Total Pages: 326

ISBN-13: 3805595670

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Asthma, allergy and chronic obstructive lung disease are common throughout the world and are increasing in incidence, particularly in the developing world. This volume provides a state-of-the-art account of the identification of new targets and the development of new therapies for these conditions. Some 40 chapters by clinical academics and senior members of the pharmaceutical industry detail the latest breakthroughs in research and development. In asthma, a promising approach is the use of therapy directed against specific Th2 responses through biological antagonists of IL-5, IL-4 and IL-13. There have also been major advances in our understanding of innate immune responses to pathogen-associated molecular patterns, and in the area of Toll-like receptors. Up to date and comprehensive, this book will be of particular relevance to those working in the pharmaceutical industry (in preclinical research and clinical development), to academic researchers in the field of respiratory medicine, and to respiratory health care specialists.


Book Synopsis New Drugs and Targets for Asthma and COPD by : T.T. Hansel

Download or read book New Drugs and Targets for Asthma and COPD written by T.T. Hansel and published by Karger Medical and Scientific Publishers. This book was released on 2010-08-31 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma, allergy and chronic obstructive lung disease are common throughout the world and are increasing in incidence, particularly in the developing world. This volume provides a state-of-the-art account of the identification of new targets and the development of new therapies for these conditions. Some 40 chapters by clinical academics and senior members of the pharmaceutical industry detail the latest breakthroughs in research and development. In asthma, a promising approach is the use of therapy directed against specific Th2 responses through biological antagonists of IL-5, IL-4 and IL-13. There have also been major advances in our understanding of innate immune responses to pathogen-associated molecular patterns, and in the area of Toll-like receptors. Up to date and comprehensive, this book will be of particular relevance to those working in the pharmaceutical industry (in preclinical research and clinical development), to academic researchers in the field of respiratory medicine, and to respiratory health care specialists.


Severe Asthma

Severe Asthma

Author: Kian Fan Chung

Publisher: European Respiratory Society

Published: 2019-06-01

Total Pages: 360

ISBN-13: 1849841047

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Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.


Book Synopsis Severe Asthma by : Kian Fan Chung

Download or read book Severe Asthma written by Kian Fan Chung and published by European Respiratory Society. This book was released on 2019-06-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.


Chronic Obstructive Pulmonary Disease Exacerbations

Chronic Obstructive Pulmonary Disease Exacerbations

Author: Jadwiga A. Wedzicha

Publisher: CRC Press

Published: 2008-09-22

Total Pages: 476

ISBN-13: 1420070878

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Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbat


Book Synopsis Chronic Obstructive Pulmonary Disease Exacerbations by : Jadwiga A. Wedzicha

Download or read book Chronic Obstructive Pulmonary Disease Exacerbations written by Jadwiga A. Wedzicha and published by CRC Press. This book was released on 2008-09-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbat


Inhaled Steroids in Asthma

Inhaled Steroids in Asthma

Author: Robert P. Schleimer

Publisher: CRC Press

Published: 2001-11-21

Total Pages: 760

ISBN-13: 9780824705855

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This book sums up the mechanistic basis, current status, and future prospects of steroid inhalation as the cornerstone of prophylactic asthma therapy, identifying its kinetic basis-especially the essential airway selectivity-and including a historical account of inhaled glucocorticoid development. Makes connections among the underlying pharmacology, impact of new simulation models, newly recognized molecular targets, and therapeutic outcomes of short- and long-term steroid inhalation therapy! Containing more than 1600 works cited, drawings, tables, equations, and micrographs, Inhaled Steroids in Asthma describes the developmental history of inhaled steroids and provides general models for lung selectivity considers the best way to select inhaled steroids clarifies local metabolism, airway and lung uptake and retention, and other determinants of once-daily usage addresses variations in lung deposition and total bioavailability among available steroids and formulations surveys the dynamics of receptor gene-mediated processes analyzes the role of chemokines in airway allergic inflammatory diseases discusses the effects of inhaled steroids in vivo on cell progenitors in asthma and rhinitis details measuring airway inflammation as a guide for treatment decisions outlines the clinical relevancy of exhaled nitric oxide in asthma covers optimal trial design for judging antiasthmatic potency and efficacy evaluates the safety of inhaled steroids Written by more than 40 of the world's leading authorities and investigators, Inhaled Steroids in Asthma is an authoritative reference for pulmonologists and pulmonary disease specialists; physiologists; allergists; immunologists; molecular, cell, and lung biologists; pediatricians; pharmaceutical scientists and pharmacologists; and medical school and upper-level undergraduate, graduate, and medical school students in these disciplines.


Book Synopsis Inhaled Steroids in Asthma by : Robert P. Schleimer

Download or read book Inhaled Steroids in Asthma written by Robert P. Schleimer and published by CRC Press. This book was released on 2001-11-21 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sums up the mechanistic basis, current status, and future prospects of steroid inhalation as the cornerstone of prophylactic asthma therapy, identifying its kinetic basis-especially the essential airway selectivity-and including a historical account of inhaled glucocorticoid development. Makes connections among the underlying pharmacology, impact of new simulation models, newly recognized molecular targets, and therapeutic outcomes of short- and long-term steroid inhalation therapy! Containing more than 1600 works cited, drawings, tables, equations, and micrographs, Inhaled Steroids in Asthma describes the developmental history of inhaled steroids and provides general models for lung selectivity considers the best way to select inhaled steroids clarifies local metabolism, airway and lung uptake and retention, and other determinants of once-daily usage addresses variations in lung deposition and total bioavailability among available steroids and formulations surveys the dynamics of receptor gene-mediated processes analyzes the role of chemokines in airway allergic inflammatory diseases discusses the effects of inhaled steroids in vivo on cell progenitors in asthma and rhinitis details measuring airway inflammation as a guide for treatment decisions outlines the clinical relevancy of exhaled nitric oxide in asthma covers optimal trial design for judging antiasthmatic potency and efficacy evaluates the safety of inhaled steroids Written by more than 40 of the world's leading authorities and investigators, Inhaled Steroids in Asthma is an authoritative reference for pulmonologists and pulmonary disease specialists; physiologists; allergists; immunologists; molecular, cell, and lung biologists; pediatricians; pharmaceutical scientists and pharmacologists; and medical school and upper-level undergraduate, graduate, and medical school students in these disciplines.


Childhood Asthma

Childhood Asthma

Author: Stanley J Szefler

Publisher: CRC Press

Published: 2005-09-26

Total Pages: 740

ISBN-13: 084935224X

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This reference collects the latest studies on the development, diagnosis, and treatment of childhood asthma and offers current perspectives on new technologies that will shape the management of pediatric asthma in the forthcoming decade-illustrating how advances in pulmonary function measurement, inflammatory markers, imaging, and pharmacogenetics


Book Synopsis Childhood Asthma by : Stanley J Szefler

Download or read book Childhood Asthma written by Stanley J Szefler and published by CRC Press. This book was released on 2005-09-26 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference collects the latest studies on the development, diagnosis, and treatment of childhood asthma and offers current perspectives on new technologies that will shape the management of pediatric asthma in the forthcoming decade-illustrating how advances in pulmonary function measurement, inflammatory markers, imaging, and pharmacogenetics


Steroids in Asthma

Steroids in Asthma

Author: Timothy John Hayes Clark

Publisher: Adis International, Limited

Published: 1983

Total Pages: 256

ISBN-13:

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Book Synopsis Steroids in Asthma by : Timothy John Hayes Clark

Download or read book Steroids in Asthma written by Timothy John Hayes Clark and published by Adis International, Limited. This book was released on 1983 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:


History of Allergy

History of Allergy

Author: K.-C. Bergmann

Publisher: Karger Medical and Scientific Publishers

Published: 2014-05-27

Total Pages: 445

ISBN-13: 3318021954

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The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading.


Book Synopsis History of Allergy by : K.-C. Bergmann

Download or read book History of Allergy written by K.-C. Bergmann and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-27 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading.


Expert Panel Report 2

Expert Panel Report 2

Author: National Asthma Education and Prevention Program (National Heart, Lung, and Blood Institute). Second Expert Panel on the Management of Asthma

Publisher:

Published: 1998

Total Pages: 164

ISBN-13:

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Book Synopsis Expert Panel Report 2 by : National Asthma Education and Prevention Program (National Heart, Lung, and Blood Institute). Second Expert Panel on the Management of Asthma

Download or read book Expert Panel Report 2 written by National Asthma Education and Prevention Program (National Heart, Lung, and Blood Institute). Second Expert Panel on the Management of Asthma and published by . This book was released on 1998 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:


The role of inhaled steroids in asthma

The role of inhaled steroids in asthma

Author: Gavin Boyd

Publisher:

Published: 1986

Total Pages: 66

ISBN-13: 9780950536798

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Book Synopsis The role of inhaled steroids in asthma by : Gavin Boyd

Download or read book The role of inhaled steroids in asthma written by Gavin Boyd and published by . This book was released on 1986 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: