Author: William H. Horrocks

Publisher: Forgotten Books

Published: 2017-02-15

Total Pages: 160

ISBN-13: 9780243334285

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Excerpt from Journal of the Royal Army Medical Corps, Vol. 31: July, 1918 I was led to this inquiry by 'my previous work on the toxic action of Copper compounds of amino-acids and in particular copper-alanine on protozoa For, in the early part of last year, in some preliminary experiments, the Opportunity for which was kindly afforded me by Professor Hewlett in the Bacteriological Laboratory, King's College, a toxic action of copper-alanine (one part in of water) was found on the meningococcus also, on thirty minutes' exposure. In further experiments carried out in association with Lieutenant Colonel Mervyn Gordon ahd Major Hine, at the Central Cerebrospinal Laboratory, Royal Army Medical College, it was shown that the meningo coccus did not survive in concentrations of copper-alanine 1 in in sodium chloride solution, on twenty minutes' exposure, but in less con centration or in broth or serum, no toxic effect was observed in this time limit. Experiments were also made with the copper-alanine in Ringer Locke solution. A somewhat more toxic effect was witnessed, as in this case the meningococcus did not survive in 1 in copper-alanine on twenty minutes' exposure. No toxic effect was observed on five or ten minutes' exposure, and as for purposes of local treatment, intrathecal or naso-pharyngeal, a short time limit is obviously essential, the above results did not indicate any special advantage in the employment of copper alanine as a bactericide in the treatment of cerebrospinal meningitis. Nor could the solutions of 1 in in ringer-locke fluid be regarded as suitable for intrathecal use without fear of injury to the delicate tissues of the central nervous system. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Download or read book Journal of the Royal Army Medical Corps, Vol. 31 written by William H. Horrocks and published by Forgotten Books. This book was released on 2017-02-15 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from Journal of the Royal Army Medical Corps, Vol. 31: July, 1918 I was led to this inquiry by 'my previous work on the toxic action of Copper compounds of amino-acids and in particular copper-alanine on protozoa For, in the early part of last year, in some preliminary experiments, the Opportunity for which was kindly afforded me by Professor Hewlett in the Bacteriological Laboratory, King's College, a toxic action of copper-alanine (one part in of water) was found on the meningococcus also, on thirty minutes' exposure. In further experiments carried out in association with Lieutenant Colonel Mervyn Gordon ahd Major Hine, at the Central Cerebrospinal Laboratory, Royal Army Medical College, it was shown that the meningo coccus did not survive in concentrations of copper-alanine 1 in in sodium chloride solution, on twenty minutes' exposure, but in less con centration or in broth or serum, no toxic effect was observed in this time limit. Experiments were also made with the copper-alanine in Ringer Locke solution. A somewhat more toxic effect was witnessed, as in this case the meningococcus did not survive in 1 in copper-alanine on twenty minutes' exposure. No toxic effect was observed on five or ten minutes' exposure, and as for purposes of local treatment, intrathecal or naso-pharyngeal, a short time limit is obviously essential, the above results did not indicate any special advantage in the employment of copper alanine as a bactericide in the treatment of cerebrospinal meningitis. Nor could the solutions of 1 in in ringer-locke fluid be regarded as suitable for intrathecal use without fear of injury to the delicate tissues of the central nervous system. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.