Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry

Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry

Author: Lauro Amezcua-Patino, MD, FAPA

Publisher: Metropolitan Consulting Corporation

Published: 2023-06-03

Total Pages: 64

ISBN-13:

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"Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry, a Patient's Guide" is an in-depth resource that offers a comprehensive understanding of ketamine's history, its current use in psychiatry, and the potential it holds for the future, all presented in an accessible and patient-friendly manner. Starting with its origins, the book takes readers on a journey from ketamine's synthesis in the 1960s, its early use as an anesthetic, to its adoption as a psychedelic drug during the counterculture era. The narrative captures the nuances of this period, providing insight into how societal perceptions and misuse led to ketamine's marginalization. The guide then transitions to a transformative period in ketamine's history, where research illuminated its potent antidepressant effects. It carefully explains how these findings have spurred a 'Ketamine Renaissance' in the 21st century, resulting in its usage for treatment-resistant depression. The book provides patient-friendly explanations of how ketamine works in the brain, its administration methods, potential side effects, and the benefits it offers. Venturing into the future, the guide presents a look at the ongoing research and potential applications of ketamine beyond depression, such as for PTSD, anxiety disorders, and chronic pain. It also discusses the development of new ketamine derivatives and its possible role within the burgeoning field of psychedelic-assisted therapy. The book concludes with practical advice for patients considering ketamine treatment, including a list of questions to ask healthcare providers, strategies for managing potential side effects, and guidance on what to expect during and after treatment. "Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry, a Patient's Guide" demystifies ketamine's journey within the realm of psychiatry, offering a balanced portrayal of its potential benefits and associated risks. This guide is an invaluable resource for patients, their loved ones, and anyone interested in understanding the role of ketamine in modern mental health treatment.


Book Synopsis Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry by : Lauro Amezcua-Patino, MD, FAPA

Download or read book Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry written by Lauro Amezcua-Patino, MD, FAPA and published by Metropolitan Consulting Corporation. This book was released on 2023-06-03 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry, a Patient's Guide" is an in-depth resource that offers a comprehensive understanding of ketamine's history, its current use in psychiatry, and the potential it holds for the future, all presented in an accessible and patient-friendly manner. Starting with its origins, the book takes readers on a journey from ketamine's synthesis in the 1960s, its early use as an anesthetic, to its adoption as a psychedelic drug during the counterculture era. The narrative captures the nuances of this period, providing insight into how societal perceptions and misuse led to ketamine's marginalization. The guide then transitions to a transformative period in ketamine's history, where research illuminated its potent antidepressant effects. It carefully explains how these findings have spurred a 'Ketamine Renaissance' in the 21st century, resulting in its usage for treatment-resistant depression. The book provides patient-friendly explanations of how ketamine works in the brain, its administration methods, potential side effects, and the benefits it offers. Venturing into the future, the guide presents a look at the ongoing research and potential applications of ketamine beyond depression, such as for PTSD, anxiety disorders, and chronic pain. It also discusses the development of new ketamine derivatives and its possible role within the burgeoning field of psychedelic-assisted therapy. The book concludes with practical advice for patients considering ketamine treatment, including a list of questions to ask healthcare providers, strategies for managing potential side effects, and guidance on what to expect during and after treatment. "Journey Through Time: Unraveling Ketamine's Past, Present, and Future in Psychiatry, a Patient's Guide" demystifies ketamine's journey within the realm of psychiatry, offering a balanced portrayal of its potential benefits and associated risks. This guide is an invaluable resource for patients, their loved ones, and anyone interested in understanding the role of ketamine in modern mental health treatment.

Ketamine

Ketamine

Author: Karl Jansen

Publisher:

Published: 2001-01-01

Total Pages: 355

ISBN-13: 9780966001938

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Book Synopsis Ketamine by : Karl Jansen

Download or read book Ketamine written by Karl Jansen and published by . This book was released on 2001-01-01 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ketamine for Treatment-Resistant Depression

Ketamine for Treatment-Resistant Depression

Author: Sanjay J. Mathew

Publisher: Springer

Published: 2016-11-25

Total Pages: 155

ISBN-13: 3319429256

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This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.


Book Synopsis Ketamine for Treatment-Resistant Depression by : Sanjay J. Mathew

Download or read book Ketamine for Treatment-Resistant Depression written by Sanjay J. Mathew and published by Springer. This book was released on 2016-11-25 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.